Mankhwala Finlepsin Retard amathandizanso kuti athetse matenda a khunyu, amathetsa ululu, ndi mavuto ena osagwirizana ndi matenda amanjenje. Zimakhudza kayendedwe ka zinthu zingapo m'thupi, chifukwa chake, mankhwalawa ayenera kugwiritsidwa ntchito moyang'aniridwa ndi katswiri. Zabwino zimaphatikizapo mtengo wotsika.
Dzinalo Losayenerana
Carbamazepine. Dzinalo Lachilatini ndi Carbamazepine.
Mankhwala Finlepsin Retard amathandizanso kuti athetse matenda a khunyu, amathetsa ululu, ndi mavuto ena osagwirizana ndi matenda amanjenje.
ATX
N03AF01 Carbamazepine
Kutulutsa mafomu ndi kapangidwe kake
Mutha kugula mankhwalawa mwa mtundu wa mapiritsi. Kusiyana kwa Finlepsin Retard ndi kukhalapo kwa chipolopolo chomwe chimadziwika ndi katundu wapadera. Imakhala ndi nthawi yayitali ya mankhwalawa. Izi zikutanthauza kuti chinthu chogwira ntchito chimamasulidwa pang'onopang'ono. Mankhwala ndi chinthu chimodzi. Chofunikira ndi carbamazepine. Kuchuluka kwake pakupanga piritsi limodzi: 200 ndi 400 mg. Zinthu zina:
- kopolymer wa ethyl acrylate, trimethylammonioethyl methacrylate, methyl methacrylate;
- triacetin;
- Copolymer wa methaconic acid ndi ethyl acrylate;
- talc;
- crospovidone;
- ma cellcose a microcrystalline;
- magnesium wakuba;
- silicon dioxide colloidal.
Mutha kugula mankhwalawa mumapaketi okhala ndi matuza atatu, 4 kapena 5 (chilichonse chili ndi mapiritsi 10).
Zimagwira bwanji?
Zopambana:
- antiepileptic;
- painkiller;
- antidiuretic;
- antipsychotic.
Zotsatira zamapangidwe amothandizirana ndi othandizirawa zimadalira njira zotchinga sodium. Mphamvu yofunikayo imatha kupezeka pokhapokha ngati amadalira magetsi. Zotsatira zake, kuchotsedwa kwa kuwonjezeka kwa mitsempha kumadziwika, zomwe zimachitika chifukwa cha kukhazikika kwa zimagwira. Komanso, mothandizidwa ndi mankhwalawa, mphamvu ya synaptic conduction ya impulses imachepa.
Maziko a antiepileptic mankhwala ndiwowonjezera malire otsika otsimikiza.
Pali kuchepa kwakukulu kwa kupanga kwa glutamate - amino acid omwe amathandizira kuwonjezera kukondwerera kwa ma neurotransmitters. Chifukwa cha malo awa, mwayi wokhala ndi khunyu umachepa. Gawo lalikulu limaphatikizidwa ndi kayendedwe ka potaziyamu, calcium ion.
Ngati trigeminal neuralgia ikukula, chifukwa cha Finlepsin Retard, zovuta zowawa zammbuyo zimachepa.
Mankhwalawa amagwira ntchito ndipo amachepetsa kukula kwa zizindikiro zosayenera ngati anthu ena akumenyedwa. Panthawi ya odwala omwe ali ndi matenda a khunyu, pamakhala kusintha kwa matenda monga nkhawa, kukhumudwa, kukwiya, kusakwiya.
Mphamvu ya antipsychotic imachitika chifukwa cha kuletsa kwa kagayidwe kazinthu ka norepinephrine, dopamine. Ndi poyizoni wa mowa, kuchuluka kwa kakulidwe kake kamachepetsa. Izi zikuchitika chifukwa cha kuwonjezeka kwa malire otsika a kukhudzika kosavuta. Ngati trigeminal neuralgia ikukula, chifukwa cha Finlepsin Retard, zovuta zowawa zammbuyo zimachepa. Kuphatikiza apo, kulandira chithandizo munthawi yake ndi mankhwalawa kumathandiza kupewa kuyambika kwa kupweteka ndi matenda.
Pharmacokinetics
Nthawi yotulutsidwa kwachangu ndi maola 12. Pakutha kwa nthawi imeneyi, kuwonjezereka kwa mulingo wogwira ntchito bwino mpaka kufika pamlingo kumadziwika. Mankhwala amatengeka kwathunthu ndi makoma am'mimba.
Zomwe zimagwira zimagwira mapuloteni a plasma omwe ali ndi mphamvu zosiyanasiyana: mpaka 60% mwa ana, 70-80% mwa odwala akuluakulu.
Njira ya kagayidwe ka carbamazepine imachitika m'chiwindi, chifukwa, 1 yogwira 1 ndi gawo limodzi losagwira limamasulidwa. Njirayi imazindikira ndi kutenga nawo gawo kwa CYP3A4 isoenzyme.
Ambiri mwa carbamazepine mu mawonekedwe osinthika amachotsedwera pokodza, gawo lochepa lomwe limakhala ndi ndowe panthawi yachinyengo. Mwa kuchuluka kumeneku, 2% yokha ya zinthu zomwe zimagwiritsidwa ntchito ndizomwe zimachotsedwa osasinthika. Mu ana, kagayidwe ka carbamazepine mofulumira. Pazifukwa izi, imagwiritsidwa ntchito pamitengo yapamwamba.
Nthawi yotulutsidwa kwachangu ndi maola 12.
Zomwe zimayikidwa
Malo ofunikira kwambiri ndi khunyu. Kuphatikiza apo, mankhwalawa amagwira ntchito mu mawonekedwe ndi zikhalidwe zina:
- khunyu ya chikhalidwe chosiyana: pang'ono,
- mitundu yosakanikirana ya khunyu;
- neuralgia yamtundu wina: mitsempha ya trigeminal, idiopathic glossopharyngeal neuralgia;
- ululu matenda ophatikizika ndi zotumphukira neuritis, zomwe zitha kukhala chifukwa cha matenda ashuga;
- zinthu zopweteka zomwe zimachitika ndi ma spasms a minofu yosalala, ma sclerosis angapo;
- kuyankhula, kusayenda bwino (matenda amisempha);
- kupweteka kwapakati ndi kupsinjika kwa dongosolo la ziwonetsero zamagetsi;
- poyizoni wa mowa;
- zovuta zama psychotic.
Contraindication
Mankhwala alibe malamulo ogwiritsira ntchito, pakati pawo dziwani:
- kuphwanya kwa hematopoietic dongosolo, lomwe limayendera limodzi ndi zochitika monga leukopenia, kuchepa magazi;
- Chipika cha AV
- matenda amtundu wa porphyria, limodzi ndi kuphwanya kagayidwe kachakudya;
- zoyipa zimachitika munthu kapena hypersensitivity.
Zambiri za pathological zimadziwika momwe kuwongolera kwa carbamazepine mu plasma ndikofunikira:
- kuphwanya mafupa hematopoiesis;
- neoplasms mu Prostate;
- kuchuluka kwapakati pa intraocular;
- kulephera kwa mtima;
- hyponatremia;
- uchidakwa.
Momwe mungatengere Finlepsin Retard
Mankhwala nawonso amagwira ntchito musanadye chakudya kapena pambuyo pake. Piritsi sangathe kutafuna, koma kusungunuka chilichonse. Chiwembuchi chimasiyana malinga ndi mtundu wa matenda. Nthawi zambiri zotchulidwa zosaposa 1200 mg wa thunthu patsiku. Mlingo umagawidwa mu 2 Mlingo, koma mutha kugwiritsa ntchito mankhwalawo kamodzi. Chiwerengero chovomerezeka tsiku lililonse ndi 1600 mg. Malangizo ogwiritsira ntchito zosiyanasiyana ma pathologies:
- khunyu: kuchuluka koyamba kwa mankhwalawa kumasiyana pakati pa 0-0-0.4 g patsiku, ndiye kuti umakulitsidwa mpaka 0,8-1.2 g;
- trigeminal neuralgia: yambani njira yochizira kuyambira 0,2-0.4 g patsiku, pang'onopang'ono mlingo umawonjezeka mpaka 0,4-0.8 g;
- poyizoni wa zakumwa zoledzeretsa: 0,2 ga m'mawa, 0,4 ga madzulo, muzovuta kwambiri, muyeso umakulitsidwa mpaka 1.2 g patsiku ndikugawidwa mu 2 waukulu;
- mankhwalawa psychotic matenda, nthawi yogwira mu angapo sclerosis: 0-0-0.4 g 2 pa tsiku.
Mankhwala nawonso amagwira ntchito musanadye chakudya kapena pambuyo pake.
Ululu wa matenda ashuga a m'mimba
Malamulo wamba: 0,2 g wa zinthu m'mawa komanso kawiri mlingo wa 0.4 g madzulo. Mwapadera, 0,6 ga amatchulidwa 2 pa tsiku.
Zimatenga nthawi yayitali bwanji
Chiwopsezo cha kugwirira ntchito chimawonedwa patadutsa maola 4-12 atayamba chithandizo.
Patulani
Sizoletsedwa kuti tingochoka mwadzidzidzi, chifukwa izi zimatha kuyambitsa vuto. Ndikulimbikitsidwa kuchepetsa mlingo pang'onopang'ono - miyezi isanu ndi umodzi. Ngati pakufunika kuletsa Finlepsin Retard, chithandizo chamankhwala choyenera chimachitika. Izi zimachepetsa mwayi wazotsatira zoyipa.
Zotsatira zoyipa za Finlepsin Retard
The vuto la mankhwalawa ali pachiwopsezo chachikulu chotengera zochita za mtundu wina poyankha mankhwala. Izi ndichifukwa choti zinthu zomwe zimapangidwa pakapangidwe kazake zimakhudzana ndi zochita za thupi. Amazindikira kuopsa kwa chizungulire, kugona, kufooka kwamphamvu kwa minofu, mutu. Kuyenda kwazomwe zimachitika, ma nystagmus, kuyerekezera zinthu m'maganizo, kukhumudwa ndi zovuta zina zamaganizidwe sizimachitika.
Matumbo
Maonekedwe auma pamlomo wamkamwa amadziwika, kulakalaka kumatha. Pali mseru, ndipo itatha - kusanza, kusintha kwa chopondapo, kupweteka pamimba. Zinthu zoterezi zimachitika: stomatitis, colitis, gingivitis, kapamba, etc.
Hematopoietic ziwalo
Anemia, leukopenia, thrombocytopenia, agranulocytosis, porphyria wa chikhalidwe china.
Kuchokera kwamikodzo
Kulephera kwamkati, nephritis, matenda osiyanasiyana a m'mitsempha amakwiya chifukwa chophwanya kwamikodzo (kusungidwa kwamadzi, kusakhazikika).
Kuchokera pamtima
Kusintha kwa intracardiac conduction, hypotension, pathological zinthu chifukwa cha kuchuluka kwa magazi m'maso komanso kuwonjezeka kwa kupatsidwa zinthu za m'magazi, zovuta za matenda a mtima, kusokonekera kwa mtima.
Kuchokera ku endocrine dongosolo ndi kagayidwe
Kunenepa kwambiri, kutupa, komwe kumalumikizidwa ndi kusungunuka kwa madzi mu minofu, momwe zotsatira za kuyesedwa kwa magazi, kusintha kwa kagayidwe ka mafupa, komwe kumayambitsa matenda a minofu.
Matupi omaliza
Urticaria. Erythroderma imayamba.
Zokhudza mphamvu pakuwongolera njira
Mankhwalawa ali ndi zovuta pa ntchito ya ziwalo zambiri ndi machitidwe, zimayambitsa zizindikiro zowopsa: chikumbumtima chofooka, kuyerekezera zinthu zina, chizungulire, etc. Pachifukwa ichi, muyenera kusamala mukamayendetsa magalimoto. Ndikofunika kusiya kusiya kuyendetsa galimoto kwakanthawi.
Malangizo apadera
Yambirani chithandizo chamankhwala ochepa. Pang'onopang'ono, kuchuluka kwa tsiku ndi tsiku kwa chinthu chachikulucho kumakula. Ndikofunikira kuwongolera kuchuluka kwa carbamazepine m'magazi.
Tiyenera kudziwa kuti chithandizo cha antiepileptic chimayambitsa maonekedwe ofuna kudzipha, chifukwa chake, wodwalayo ayenera kuyang'aniridwa mpaka njira yamankhwala ithe.
Asanayambe chithandizo, mkhalidwe wa chiwindi ndi impso umayesedwa. Ndikofunikira kuti muyesedwe magazi, mkodzo mayeso, electroencephalogram.
Gwiritsani ntchito mu ukalamba
Amaloledwa kugwiritsa ntchito mankhwalawa kwa odwala azaka zopitilira 65. Komabe, mlingo woyenera ndi 0,2 ga patsiku kamodzi.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Mankhwala amatha kulowa mu placenta kupita mkaka wa m'mawere, ndipo kuchuluka kwa carbamazepine pamenepa ndi 40-60% ya kuchuluka konse komwe kumakhala m'magazi. Pa nthawi ya bere, pamakhala chiopsezo chotenga ma pathologies mu fetus ndikumwa mankhwala omwe mukufunsidwa. Komabe, imaloledwa kugwiritsa ntchito mankhwalawa, koma iyenera kuchitidwa pokhapokha ngati zikuwonetsedwa mwamphamvu, ngati zotsatira zabwino za chithandizo zipitilira kuvulaza.
Kupangira Finlepsin Kubwerera kwa Ana
Analoleza kulandira chithandizo kwa odwala azaka 6. Mulingo woyenera ndi 0,2 ga patsiku. Kenako imakulitsidwa ndi 0.1 g mpaka zotsatira zomwe mukufuna.
The ntchito aimpso kuwonongeka
Mankhwala amavomerezeka kuti agwiritsidwe ntchito pa pathologies a chiwalo ichi, komabe, ndikofunikira kuyang'anira momwe wodwalayo alili.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Amaloledwa kupereka mankhwala pankhaniyi. Ngati vuto la chiwindi likulephera, muyenera kusokoneza maphunzirowo.
Kugwiritsa ntchito mankhwalawa kumaloledwa ngati chiwindi chayamba kugwira ntchito.
Zoyenera kuchita ndi bongo wa Finlepsin retard
Zowonetsa zingapo zoyipa zimadziwika kuti zimachitika ndi kuwonjezeka pafupipafupi komanso kwakukulu kwa kuchuluka kololedwa kwa carbamazepine:
- chikomokere
- kuphwanya kwamanjenje: kuchepa, kugona, kusasunthika, kuwonongeka kwa mawonekedwe;
- hypotension;
- kusokonezeka kwa mtima;
- kuletsa kwa ntchito ya kupuma;
- kusanza ndi mseru;
- kusintha zotsatira za mayeso a labotale.
Chitani chithandizo chofuna kuthetsa zotsatirapo zake. Nthawi yomweyo, amawunika ntchito zamtima, amawongolera kutentha kwa thupi. Kuwongolera kwa kusowa kwa madzi m'magetsi kumachitika. Mlingo wa yogwira mankhwala m'mwazi umatsimikiza. Kupukusa kwa m'mimba kumachitika. Muzimvera. M'malo mochita kukonzanso kaboni, wothandizira aliyense wa gululo angayikidwe: Smecta, Enterosgel, etc.
Kuchita ndi mankhwala ena
Musanayambe chithandizo, dziwani za zovuta zomwe zingachitike chifukwa cha kugwiritsa ntchito mankhwala ena.
Ndi chisamaliro
Mankhwala otsatirawa amalimbikitsa kuchuluka kwa zigawo zikuluzikulu za m'magazi: Verapamil, Felodipine, Nicotinamide, Viloxazine, Diltiazem, Fluvoxamine, Cimetidine, Danazole, Acetazolamide, Desipramine komanso mankhwala angapo a macrolide. Pazifukwa izi, kusintha kwa mankhwalawa kumachitika kuti matenda a carbamazepine akhale osavuta.
Pali kuwonjezeka kwa mphamvu ya folic acid, praziquantel. Kuphatikiza apo, kuchotsedwa kwa mahomoni a chithokomiro kumalimbikitsidwa.
Pali kuwonjezeka kwa mphamvu ya Finlepsin Retard mukaphatikizidwa ndi Depakine.
Kuphatikiza sikofunikira
Kukhazikitsidwa kwa Finlepsin Retard, limodzi ndi mankhwala ena oletsa CYP3A4 kumayambitsa chitukuko cha zotsatira zoyipa. Momwemonso, CYP3A4 inducers amathandizira kuyendetsa kagayidwe kazinthu kagayidwe kachakudya ndi kameneka, komwe kamayambitsa kuchepa kwamphamvu kwa mankhwalawa.
Kuyenderana ndi mowa
Sizoletsedwa kumwa zakumwa zoledzeretsa zam'kati pochita mankhwala ndi Finlepsin. Zinthu zimachitika motsatira mfundo zotsutsana, pomwe pakuchepa mphamvu ya mankhwalawa.Kuphatikiza apo, mowa umakulitsa katundu pa chiwindi.
Analogi
M'malo mogwira mtima:
- Carbamazepine;
- Finlepsin;
- Tegretol;
- Tegretol CO.
Kupita kwina mankhwala
Kupezeka kokha ndi mankhwala.
Kodi ndingagule popanda kulandira mankhwala?
Ayi.
Mtengo Wogulitsa Finlepsin
Mtengo wapakati umasiyana ndi ma ruble a 195-310.
Zosungidwa zamankhwala
Kutentha kwa mpweya sikuyenera kupitirira + 30 ° С.
Tsiku lotha ntchito
Pambuyo pazaka 3 kuyambira tsiku lopanga, simungathe kugwiritsa ntchito mankhwalawa.
Wopanga
Ntchito za Teva Poland, Poland.
Ndemanga pa Finlepsin Retard
Marina, wazaka 36, Omsk
Mankhwalawa adalangizidwa kwa mwamuna wake pambuyo poti amenyedwa. Kubwezeretsa kudachitika popanda zovuta, mwachangu mokwanira. Mwamuna adamwa mankhwalawa patatha chaka chimodzi. Panalibe mavuto.
Veronika, wazaka 29, Nizhny Novgorod
Ndili ndi nkhawa (osati ya khunyu). Pambuyo pake ndidayamba kumwa mankhwalawo. Koma sakuyenererana: mkhalidwe wagona ndipo pali kubweza komwe kumachitika.
