Anti-wodziwikiratu maantibayotiki akugwira ntchito motsutsana ndi ma pathogenic angapo, kuphatikiza mabakiteriya osokoneza gramu komanso gramu. Mu mawonekedwe ake 2 omwe amagwira ntchito, wopangayo anawonjezera zina zothandizira. Kugwiritsa ntchito mankhwalawa kumachitika ndi chilolezo cha katswiri yemwe amasankha payekha mlingo ndi njira yoyendetsera. Amadzipatula nokha. Ali ndi zophwanya, kuphatikiza ndi achibale, chifukwa chomwe chofunikira chilandira chimafunikira moyang'aniridwa ndi katswiri.
Ndi chisamaliro
Kusamala ndikofunikira kwa anthu omwe ali ndi mbiri yakutupa kwamatumbo akulu. Contraindication wachibale imaphatikizanso kwambiri aimpso pathologies, chiwindi kulephera, oyamba omaliza a fetal mapangidwe ndi kuyamwitsa.
Anti-wodziwikiratu maantibayotiki akugwira ntchito motsutsana ndi ma pathogenic angapo, kuphatikiza mabakiteriya osokoneza gramu komanso gramu.
ATX
Mankhwala apatsidwa nambala ya ATX - J01CR02.
Kutulutsa mafomu ndi kapangidwe kake
Mankhwalawa amapezeka mu mawonekedwe a piritsi ndi mawonekedwe a ufa pokonzekera kuyimitsidwa. Mitundu yonse ya Mlingo imakhala ndi zinthu zofananira zosiyanasiyana zamagawo osiyanasiyana. Zowonjezera zina zimasiyana.
Mapiritsi
Piritsi lamapiritsi la antioxotic momwe limapangidwira limakhala ndi zida zazikulu komanso zothandiza. Zinthu zomwe zimagwira ndi monga mchere wa clavulan potaziyamu (125 mg) ndi amoxicillin trihydrate (500 mg). Zowonjezera:
- polysorb;
- polyvinylpyrrolidone insoluble;
- E468;
- E572;
- E460 (MCC).
Piritsi lililonse limakhala lofanana ndi filimu ya enteric. Kanema wachimake mu kapangidwe kake kali ndi:
- hypromellose;
- mapangidwe a ethyl cellulose;
- talc;
- triethyl citrate.
Amoxicillin motsogozedwa ndi asidi amayamba kugonjetsedwa ndi β-lactamases.
Mapiritsi a Biconvex oyera (ochepa zonona) amawaika m'matumba (5-7 ma PC.) Ndi mabotolo agalasi (ma 15-21 pcs.). Chiwerengero cha matuza mu kabokosi katoni - 2-4 ma PC. Phukusi limakhala ndi zofunikira (chidziwitso cha wopanga, chiwerengero cha batch, moyo wa alumali).
Ufa
Zomwe zikuluzikulu za fomu ya Mlingo ndizofanana ndi piritsi. Masewera a amoxicillin (500-1000 mg) ndi clavulan (100-200 mg) amatha kusiyanasiyana. Lyophilisate ndi zinthu zoyera za ufa, zokutira m'mabotolo amgalasi oyera. Khosi lazitsulo limasindikizidwa ndi cholembera ndikukutira ndi zojambulazo.
Mbale za ufa zimayikidwa m'mabokosi amakatoni, kumbuyo komwe zimapangidwira, kutentha ndi nthawi yosungirako zimawonetsedwa. Mu phukusi - zosaposa 5 thovu. Malangizo ogwiritsira ntchito amapezeka m'bokosi lililonse.
Zotsatira za pharmacological
Maantibayotiki momwe amapangira amakhala ndi semisynthetic penicillin ndi clavulanic acid. Wotsirizirayi ali ndi udindo wopatsa zovuta kukhazikika ma beta-lactamases omwe amapanga tizilombo tating'onoting'ono. Amoxicillin motsogozedwa ndi asidi amayamba kugonjetsedwa ndi β-lactamases.
Clavulan, monga mankhwala a beta-lactam, ali ndi mphamvu yoletsa thupi. Mankhwalawa amagwira ntchito motsutsana ndi angapo othandizira tizilombo, kuphatikizapo gramu, gram-negative, anaerobic tizilombo. Mitundu yoyipa:
- Gardnerella vaginalis;
- Streptococcus pneumoniae;
- Enterococcus faecalis;
- Streptococcus pyogene ndi beta hemolytic streptococci;
- Streptococcus viridans.
Zovuta zopanda gram:
- Eikenella corrodens;
- Moraxella catarrhalis;
- Capnocyptophaga spp;
- Pasteurella multocida;
- Haemophilus fuluwenza.
Pambuyo polowa m'mimba, zinthu zazikulu za mapiritsi zimayamwa mwachangu m'magazi ndikunyamulidwa m'thupi lonse.
Mabakiteriya a Anaerobic:
- Fusobacterium nucleatum;
- Bacteroides fragilis;
- Prevotella spp.
Tizilombo toyambitsa matenda:
- Enterobacter sp;
- Morganella morganii;
- Citrobacter freundii;
- Stenotrophomonas maltophilia;
- Acinetobacter sp;
- Serratia sp;
- Providencia spp.
Nthawi zambiri, kukana kwa tizilombo tina timene timapeza chifukwa cha kugwiritsidwa ntchito kwa nthawi yayitali kwa mankhwala othandizira.
Pharmacokinetics
Njira zowola za zinthu zonse zogwira ntchito ndizofanana. Pambuyo polowa m'mimba, zinthu zazikulu za mapiritsi zimayamwa mwachangu m'magazi ndikunyamulidwa m'thupi lonse. Ma jakisoni a intravenous (kawirikawiri intramuscular) amathanso kuyamwa mwachangu kuchokera kumalo opangira jakisoni.
Kuzindikira kwakukulu m'magazi kumadziwika maminiti 60 pambuyo pa mlingo woyamba. Zigawo zonsezi zimagawidwanso m'zigawo zofewa ndi madzi. M'malingaliro ang'onoang'ono, amoxicillin amapezeka m'mimba, m'chiberekero, m'mapapo, chiwindi, mosiyanasiyana, tinthu tating'onoting'ono, zotupa ndi minofu.
Zinthu zomwe zimagwira ntchito sizitha kuthana ndi BBB, koma zimapezeka mkaka wa m'mawere ndi placenta. Pafupifupi sikugwirizana ndi mapuloteni. Part metabolism, chimbudzi chimachitika ndi impso ndi matumbo mu maola 1.5-2.
Kugwiritsa ntchito maantibayotiki pakuchiritsa ndi prophylactic zolinga ndikololedwa ngati wodwala wapezeka ndi matenda a etiology.
Zizindikiro zogwiritsidwa ntchito
Kugwiritsa ntchito maantibayotiki pakuchizira ndi prophylactic zolinga zimaloledwa ngati wodwala wapezeka ndi matenda a etiology opatsirana omwe amayambitsidwa ndi tizilombo tating'onoting'ono tomwe timayang'ana pazinthu zomwe zimagwira popanga mankhwalawa. Izi zikuphatikiza:
- chapamwamba kupuma thirakiti matenda (sinusitis, otitis media, pharyngitis, tonsillitis);
- matenda ochepa kupuma thirakiti (bronchitis, chibayo);
- matenda a genitourinary dongosolo (cystitis, vaginosis);
- matenda a pakhungu, kuphatikiza kulumidwa ndi tizirombo ndi zotupa pa maliseche akunja a akazi;
- zotupa zamafupa;
- Matenda a biliary thirakiti la matenda achilengedwe (cholangitis).
Kugwiritsa ntchito maantibayotiki ndikotheka ndikupanga matenda a odontogenic.
Contraindication
Mankhwala ali ndi zingapo zotsutsana. Izi zikuphatikiza:
- mbiri ya jaundice wa cholestatic;
- matenda akulu a chiwindi;
- mononucleosis ya etiology yopatsirana;
- zaka za ana (mpaka zaka 12);
- Hypersensitivity kwa zigawo zikuluzikulu za mankhwala;
- tsankho limodzi la cephalosporins ndi penicillins gulu.
Ndi kulephera kwa aimpso, kugwiritsira ntchito mosamala mtundu uliwonse wa mlingo uyenera.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Akatswiri salimbikitsa kugwiritsa ntchito mankhwala othandizira prophylactic komanso achire panthawi yoyembekezera komanso yoyamwitsa. Mu malangizo ogwiritsa ntchito, nthawizi zimawonetsedwa ngati zotsutsana. Kutenga mawonekedwe pakamwa ndikotheka ngati pali choopsa pamoyo wa mayi. Mu magawo amtsogolo, simungathe kulowa mankhwalawo mu / m kapena / mu.
Momwe mungatenge Amoxiclav 2?
Mankhwala osokoneza bongo amatha kuchitika kunyumba. Mlingo ndi maphunziridwe ake audindo amasankhidwa payekha, kutengera mtundu wa wodwala komanso kuchuluka kwa matendawo.
Akuluakulu
The lyophilisate sitimadzipereka ndi madzi jakisoni. Ndikofunikira kuyang'anira mtundu wamadzi: njira yodzala ndi mitambo ndiyofunika kutayidwa. Mankhwalawa achire a mankhwalawa sayenera kupitirira 30 ml. Kuti zitheke, imayendetsedwa pang'onopang'ono, katatu patsiku. Sikulimbikitsidwa kuyendetsa zoposa 10 ml (1 botolo la 500 mg / 100 mg). Njira yotsirizirayi imalowetsedwa pang'ono m'semtsempha.
Odwala omwe adapezeka kuti ali ndi matenda a shuga angafunike kusintha njira.
Mapiritsi a mankhwalawa amatengedwa kwathunthu, makamaka kumayambiriro kwa chakudyacho, kuyamwa koyenera komanso kupewa kuyipa kwa m'mimba. Zowonjezera za tsiku ndi tsiku sizoposa mapiritsi atatu. Njira yovomerezeka ndi masiku 10 mpaka 14. Itha kuwonjezeredwa ndi chilolezo cha dokotala popezeka kuti alibe.
Mlingo wa ana
Ana amapatsidwa mawonekedwe a piritsi. Chizolowezi achire zimatengera thupi la mwana. Achinyamata omwe kulemera kwawo kupitilira 40 makilogalamu amapatsidwa 10 mg / kg ya clavulanic acid, amoxicillin - osapitirira 45 mg / kg.
Kumwa mankhwala a shuga
Odwala omwe adapezeka kuti ali ndi matenda a shuga angafunike kusintha njira. Kulandila ndibwino kuyamba ndi theka Mlingo.
Zotsatira zoyipa
Amoxiclav 2, ngati itagwiritsidwa ntchito molakwika, imatha kuyambitsa zovuta zoyipa.
Matumbo
Kuchokera pamimba, kupukusa m'mimba kumawonedwa, kuphatikiza ululu wa epigastric, dyspepsia, kutsegula m'mimba, ntchito yowonjezera ya AST ndi ALT.
Amoxiclav 2, ngati imagwiritsidwa ntchito molakwika, imatha kuyambitsa matenda otsegula m'mimba.
Hematopoietic ziwalo
Kuchokera kuzungulira kwa dongosolo, thrombocytopenia, leukopenia, hemolytic anemia ndi pancytopenia amasiyanitsidwa.
Pakati mantha dongosolo
Chizungulire, migraine, kusokonezeka kwa tulo (kusowa tulo, kugona), kuda nkhawa, kusokonezeka kwa malingaliro am'mbuyo kumachitika chifukwa cha zovuta zoyambira pakati.
Kuchokera kwamikodzo
Kuchokera kwamkodzo dongosolo, makristasi ndi njira zotupa mu impso amapatula (kawirikawiri).
Matupi omaliza
Nthawi zambiri, ziwonetsero zimawonekera mu mawonekedwe a totupa pakhungu, urticaria, kuyabwa ndi khungu. Pafupipafupi - kuwopsa kwa anaphylactic ndi edema ya Quincke.
Malangizo apadera
Pogwiritsa ntchito nthawi yayitali, ndikofunikira kuti mupitirize kuyesa magazi ndi mkodzo pafupipafupi. Izi zitha kukhala zabodza chifukwa chogwiritsa ntchito njira ya Feling. Kugwiritsa ntchito piritsi lamankhwala piritsi limodzi nthawi yomweyo monga chakudya kumachepetsa chiopsezo cha dyspepsia.
Pogwiritsa ntchito nthawi yayitali, ndikofunikira kuti mupitirize kuyesa magazi ndi mkodzo pafupipafupi.
Kuyenderana ndi mowa
Kumwa mowa panthawi ya mankhwala ochepetsa mphamvu ya kachilombo ka mankhwala ndi zoletsedwa. Ethanol pamodzi ndi amoxicillin amakhumudwitsa kukula kwa kuledzera.
Zokhudza mphamvu pakuwongolera njira
Ngati wodwalayo alibe zotsatirapo za kugona, ndiye kuti kuyendetsa ndi magalimoto ena kumaloledwa.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Matenda a chiwindi ndi otsutsana. Kusintha kwa magazi kungafunike.
The ntchito aimpso kuwonongeka
Ndi pathologies a impso, mankhwalawa aledzera maola 24 aliwonse. Zomwe zimachitika tsiku ndi tsiku sizopitirira 1 piritsi. Mukamagwiritsa ntchito, kuyang'anira chilolezo cha creatinine ndikofunikira.
Bongo
Palibe chidziwitso chodalirika cha zotsatira zakupha ndi mankhwala osokoneza bongo. Matenda a wodwalayo amachepa kwambiri ndipo zizindikilo zake zimakhala, monga:
- kusanza kosasamala;
- kupweteka pachifuwa;
- Chizungulire
- kukokana
- kusowa tulo
Zizindikiro zoyambirira za malaise zikaonekera, muyenera kulankhulana ndi achipatala msanga. Kuchiza ndi mankhwala. Thandizo loyamba limakhala kutsuka m'mimba ndikumatenga enterosorbent (makala ophatikizidwa). Palibe mankhwala.
Kuchita ndi mankhwala ena
Zigawo za Chondroitin, aminoglycoside, antacid, laxatives zimatha kuchepetsa kuyamwa. Ascorbic acid imawonjezera kuyamwa kwa zinthu zomwe zimagwiritsidwa ntchito popanga mankhwala. Mankhwala omwe amalepheretsa kupanga calcium (NSAIDs, diuretics, phenylbutazone) amatha kuwonjezera kuchuluka kwa zinthu zomwe zimagwira.
Nthawi yomweyo kayendedwe ka anticoagulant ndi mankhwala ayenera kuyang'aniridwa ndi katswiri. Pankhani ya kusatsatira malamulo azachipatala, kuchuluka kwa prothrombin kumawonedwa. Maantibayotiki atha kuwonjezera kuchuluka kwa antimetabolite. Allopurinol ndi mankhwala akumwa mankhwala kumawonjezera mwayi wokhala ndi exanthema. Disulfiram sagwirizana ndi mankhwalawa.
Analogi
Mankhwala ochepetsa mphamvu ya penicillin ali ndi zoloweza mmalo zingapo zomwe zimachitikanso chimodzimodzi. Izi zikuphatikiza:
- Zosangalatsa. Macrolide antiotic ndi azalide yokhala ndi zochita zingapo. Amapezeka mu mawonekedwe a ufa, kuchokera komwe kuyimitsidwa kumakonzedwa. Chofunikira kwambiri ndi azithromycin dihydrate. Ili ndi katundu wotchedwa antimicrobial. Yogwira motsutsana ndi staphylococci ndi streptococci. Mtengo m'mafakitale amachokera ku ma ruble 215.
- Flemoklav. Analogue yaumbidwe yokhala ndi mawonekedwe ofanana ndi oyambirirawo. Udindo wazinthu zogwira ntchito ndi amoxicillin ndi clavulan. Amapezeka mu mawonekedwe a mapiritsi okhala ndi mitundu yosiyanasiyana ya zinthu zomwe zimagwira. Mtengo muma pharmacies ndikuchokera ku ruble 300.
- Flemoxin. Maantibayotiki omwe ali mgulu la penicillin ndi analog ya ampicillin. Amapezeka piritsi. Mphamvu ya antibacterial ilipo. Mtengo wa mawonekedwe a mankhwalawa m'masitolo amakanema ndi ma ruble 230.
Analogue iliyonse imapezeka pa mankhwala. Contraindication ndi zotheka zoyipa zimayikidwa mu malangizo.
Kupita kwina mankhwala
Kutulutsa kwina kulikonse kwamankhwala kumafunikira kuti mupatsidwe mankhwala.
Kodi ndingagule popanda kulandira mankhwala?
Ndizosatheka kugula maantibayotiki popanda mankhwala.
Zosungidwa zamankhwala
Mankhwalawa akuphatikizidwa pamndandanda B. Sungani pamawonekedwe osapitirira + 25 ° C pamalo odera, ozizira, otetezeka.
Tsiku lotha ntchito
Sungani miyezi yopitilira 24.
Ndemanga pa Amoxiclav 2
Ndemanga za mankhwalawa zalembedwa pansipa.
Madokotala
Kirill Andreev, katswiri wofalitsa matenda, Voronezh.
Ndimapereka mankhwala nthawi zambiri odwala, amakhutira ndi zotsatirapo zake. Ndikofunikira kutsatira malangizo onse a adokotala, imwani mapiritsi molingana ndi mtundu wa mankhwala. Ngati mukumva kusowa bwino, ndikulimbikitsa kuti ndisiye chithandizo.
Svetlana Zavyalova, dermatologist, Samara.
Mankhwalawa ndi othandizira, koma odwala nthawi zambiri amadandaula za zotsatira zoyipa kuchokera ku Amoxiclav. Nthawi zambiri, mavuto ang'onoang'ono ang'onoang'ono amawonekera ngati mawonekedwe totupa pamtondo wapamwamba wa dermis. Amatha kuchiritsidwa ndi mafuta a antihistamine, omwe allergist angakuthandizeni kusankha.
Odwala
Evgenia Baratyntseva, wazaka 47, Rostov-on-Don.
Matenda a shuga amachepetsa chitetezo cha mthupi, matenda a bronchitis adapezeka. Panthawi yochulukirachulukira, sizimatheka kugona komanso kupuma. Ndinavutika masiku 4, ndinapita kwa adotolo. Adalemba mankhwala, adagula ndi mankhwala. Mankhwalawa adathandizira, sindimamva zowawa zilizonse.
Anatoly Verd, wazaka 72, Ekaterinburg.
Ndakhala ndikuvutika ndi matenda ashuga kwa zaka 34. Matenda opatsirana am'mapapo amapezeka nthawi zambiri. Kusuta kwayamba ndi mankhwala “opepuka”, asiya kuthandiza. Amalemba mankhwala amphamvu. Kuthandizidwa mwachangu. Patsiku loyamba, ndinamva kugona, komwe kudutsa tsiku lotsatira.
Mtengo wa Amoxiclav 2
Mtengo wa mankhwala pama pharmacies, kutengera mtundu wa kumasulidwa ndi mlingo, umayamba kuchokera ku ma ruble 94.
