Mankhwalawa ndi a gulu la mankhwala a he hetaticatic, kugwiritsa ntchito kwake komwe kumapangitsa prophylactic ndi achire chifukwa cha kukhalapo kwa antihemorrhagic. Mphamvu ya mankhwalawa imachitika chifukwa cha luso lotha kutsimikiza mtima wamagazi. Mankhwala ali ndi zotsutsana. Kulandila kwa mtundu wina wa mulingo uyenera kuchitika malinga ndi malangizo ogwiritsira ntchito.
ATX
B02BX01.
Kutulutsa mafomu ndi kapangidwe kake
Wopanga amapereka mitundu iwiri yayikulu yomasulira mankhwala: mapiritsi ndi yankho.
Ethamsylate ndi m'gulu la mankhwala omwe amakhazikika.
Chofunikira chachikulu mu mitundu yonseyi ndi ethamylate (mu Chilatini - Etamsylate). Zomwe zili pazinthuzo mu yankho (2 ml) sizidutsa 125 mg, piritsi - osapitirira 250 mg. Zothandiza pazomwe zimapangidwira mawonekedwe aliwonse azikhala ngati olimbitsa.
Zomwe mapiritsiwo amaphatikizira ndi izi:
- polima wosungunuka;
- wowuma masamba (chimanga);
- stearic acid;
- utoto wa chakudya (kutengera wopanga);
- shuga mkaka (lactose).
Yankho lili:
- sodium bicarbonate (bicarbonate);
- sodium pyrosulfite;
- madzi oyeretsedwa.
Zomwe zimagwiritsidwa ntchito mu yankho siziposa 125 mg.
Mapiritsi a mawonekedwe olondola ozungulira, oyera kapena amtundu wapinki komanso ochepa. Chamfer ndi chiwopsezo zilipo. Ndi gawo lalitali la piritsi, kupindika koyera koyera kumawoneka bwino. Filimu yophimba mtundu wa Mlingo ulipo. Mapiritsi ali m'miyeso 10-mesh cell. m'modzi aliyense.
Yankho la jakisoni limathiridwa mu ma ampoules a galasi omveka bwino. Pali zikwangwani za buluu pachidebe pamalo oyambapo. Jekeseni wa ma ampoules amalowetsedwa m'mapulasitiki apulogalamu ya 5 ma PC. Mitundu yonse ya Mlingo imapitilira kugulitsa makatoni. Malangizo ogwiritsira ntchito - amapezeka.
Njira yamachitidwe
Limagwirira a zochita za mankhwalawa amatengera mphamvu ya mankhwalawa.
Ndi mankhwala pafupipafupi, kupezeka kwamitsempha kwamtundu wa makina kumapangidwira, kuphatikiza kuphatikizika kwa capillary. Kuchulukitsa kwamwazi kumabwezeretseka.
Ndi nthawi yochulukirapo, mankhwalawa amachepetsa kuchuluka kwa mitsempha. Mankhwala amatha kuyambitsa mapangidwe a thromboplastin. Mothandizidwa ndi mankhwalawa, kuchuluka kwa magazi a magazi kumawonjezeka, monganso momwe zimagwirira maselo ambiri. Mankhwala amalepheretsa kukula kwa thrombosis ndi mapangidwe wamagazi. Hypercoagulant katundu wa mankhwala kulibe.
Mothandizidwa ndi mankhwala, kuchuluka kwa magazi a magazi kumawonjezeka.
Pharmacokinetics
Mukamamwa pakamwa, kufalikira kwa mtundu wa milingo kumachitika m'mimba. Mankhwalawa amayamba kugwira ntchito mphindi 20-30 atatha kugwiritsa ntchito. Kuzindikira kwakukulu m'magazi kumafika pambuyo pa mphindi 60. The pharmacological zotsatira kumatenga maola 6-7. Kutha kwa theka-moyo kumatenga maola 1,5-2.
Njira yothetsera jakisoni wa intramuscular imafalikira mofulumira kupita ku minofu yofewa mwachindunji kuchokera pamalo a jekeseni. The achire zotsatira amapezeka 15-30 mphindi. Mankhwalawa amaphatikizidwa m'chiwindi, ngakhale atamasulidwa bwanji. Ma metabolites omwe amagwira ntchito kulibe. Kuchulukitsa kumachitika ndi impso; zosaposa 2% ndizopanda zosasinthika.
Zomwe zimayikidwa
Kugwiritsa ntchito mankhwalawa pochiritsa anthu kumachitika ndi ma pathologies omwe angayambitse magazi. Izi zikuphatikizapo matenda ashuga angiopathy ndi hemorrhagic diathesis. Mankhwalawa amagwiritsidwa ntchito kwambiri pochita opaleshoni m'malo a ophthalmic, mano, urological, gynecological and otolaryngic.
Mankhwalawa amagwiritsidwa ntchito kwambiri pakuthandizira opaleshoni m'malo a ophthalmic.
Mankhwalawa amagwiritsidwa ntchito msambo kuti magazi asatayike kwambiri. Kugwiritsa ntchito zovuta za hemorrhagic kumaloledwa pazifukwa zaumoyo, kuphatikiza kugwiritsa ntchito mwadzidzidzi kukha magazi kwa m'mapapo ndi m'mimba.
Contraindication
Kugwiritsa ntchito mankhwalawa monga gawo la monotherapy yamatumbo omwe amakwiya chifukwa chogwiritsa ntchito anticoagulants ndi zoletsedwa.
Main contraindication ndi:
- thrombosis
- thromboembolism.
Odwala a Hypersensitive amalangizidwa kuti asamwe mankhwalawo.
Momwe angatenge
Mankhwala ayenera kumwedwa mosasamala mtundu wa kumasulidwa malinga ndi mtundu wa mankhwalawa. Mankhwalawa amatengedwa pakamwa (mapiritsi), kutumikiridwa intramuscularly, retrobulbarly, intravenously (solution) komanso kunja. Kulowetsedwa (kulowetsedwa) jakisoni kumachitika mu chipatala chapadera. Mlingowo umatsimikiziridwa ndi katswiri kutengera mkhalidwe wa wodwala.
Njira imodzi yovomerezeka yothetsera vutoli ndi 150-250 ml katatu patsiku. Chiwerengero cha tsiku lililonse cha mapiritsi a odwala akuluakulu sayenera kupitirira mapiritsi 6 patsiku. Malinga ndi malangizo, mapiritsiwa saloledwa kumwa pamimba yopanda kanthu. Mapiritsi ayenera kuledzera nthawi yakudya kapena itatha.
Kugwiritsa ntchito kunja kumachitika pogwiritsa ntchito bandeji yophika yokhazikika mu yankho la mankhwala mwachindunji pachilonda.
Masiku angati
Kugwiritsa ntchito mankhwalawa kumachitika m'maphunziro. Kutalika kwa maphunzirowa ndi masiku 10 mpaka 14. Pakati pa maphunziro, muyenera kuchita yopuma masiku 7-10.
Ndi matenda a shuga 1
Pochiza matenda ashuga, muyezo wa mankhwala omwe katswiri adawunika ayenera kuonedwa. Mlingo woyenera wa mapiritsi ndi 250-500 mg katatu patsiku kwa masiku 10.
Pochiza matenda ashuga, muyezo wa mankhwala omwe katswiri adawunika ayenera kuonedwa.
Kubweretsa yankho kumachitika mu / m kapena / kuchuluka kwa 2-4 ml kawiri pa tsiku kwa masiku 14. Ndikofunikira kugwiritsa ntchito ma syringe ndi singano zazifupi.
Zotsatira zoyipa
Mlingo wosankhidwa molakwika umatha kukulitsa zovuta zingapo zoyipa.
Matumbo
Kuchokera pamimba, m'mimba, kupweteka mseru, kusanza, ndi kupweteka kwa epigastric kumawonedwa.
Hematopoietic ziwalo
Kumbali ya ziwalo za hemopoietic, kukula kwa tachycardia, kudumpha kuthamanga kwa magazi, kupweteka pamtima kumawonedwa.
Kumwa mankhwalawa kumatha kusokoneza magazi, chifukwa khungu limasanduka cyanotic.
Pakati mantha dongosolo
Kuchokera kumbali yamanjenje yapakati, chizungulire, kusokonezeka kwa kugona (kugona kapena kugona tulo), kunjenjemera kwa malekezero ena kumawonekera.
Zotsatira zoyipa za kumwa mwa mankhwalawa zimaphatikizanso kugona tulo.
Kuchokera kwamikodzo
Nthawi zina, kuphwanya mkodzo kumatuluka.
Matupi omaliza
Mankhwalawa samachititsa kuti thupi lizigwirizana.
Malangizo apadera
Kugwiritsa ntchito mankhwala kwa ana kungafunike kusintha kwa mankhwalawa. Ana akuletsedwa mwamphamvu kupereka zoposa mapiritsi a 2-3 patsiku; Mlingo uliwonse umawerengeredwa potengera kulemera kwa mwana (mpaka 15 mg / kg).
Kuyenderana ndi mowa
Mankhwalawa sagwirizana ndi mowa. Ethanol osakanikirana ndi yogwira pophika muyezo wa mankhwalawa amachititsa kuledzera kwamthupi ndikupangitsa kuti chiwindi chiwonjezeke.
Mankhwalawa sagwirizana ndi mowa.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Kugwiritsa ntchito mankhwalawa poyerekeza ndi amayi apakati (ine trimester) kumachitika moyang'aniridwa ndi adokotala komanso pazifukwa zaumoyo. Palibe chidziwitso chazomwe zingavulaze mwana wosabadwayo.
Bongo
Wopanga sanapereke zambiri zolaula.
Kuchita ndi mankhwala ena
Palibe chidziwitso pakuyenderana kwa mankhwala a antihemorrhagic ndi mankhwala ena.
Analogi
Pali ma analogues akuluakulu angapo (malinga ndi ATX) ndi ma genics.
Zomwe zikuluzikulu ndi izi:
- Eskom. Imapezeka ngati yankho la jakisoni. Chosakaniza chachikulu chogwira ntchito ndichofanana ndi choyambirira. Imaletsa magazi a ma etiology osiyanasiyana, imalimbitsa makoma amitsempha yamagazi. Mtengo woyenerera - ma ruble 90-120.
- Dicinon. Hemostatic, mwachindunji kapangidwe ka analogue (kapangidwe kake) koyambirira. Amapezeka mu mawonekedwe a yankho ndi mapiritsi. Amamwa mwachangu komanso kugawa. Pali zotsutsana. Mtengo muma pharmacies umachokera ku ma ruble 130.
Zambiri zimaphatikizapo:
- Tranexam. Mankhwala osokoneza bongo omwe amakhala ngati oletsa matenda a fibrinolysis. Imathandizira mapangidwe a plasmin. Amapezeka piritsi. Imalepheretsa kukula kwa magazi, kuphatikizapo uterine, matumbo ndi m'mapapo. Mtengo - kuchokera ku ma ruble 80.
- Vikasol. Mankhwala a antihemorrhagic, omwe ali analogue a Vitamini K. Njira yotulutsira ndi njira yothetsera jakisoni. Chizindikiro chachikulu chogwiritsa ntchito ndi hemorrhagic syndrome. Mtengo - kuchokera ku ma ruble 120.
Pafupifupi ma analogu onse amafunikira kuti apatsidwe mankhwala kuchokera kuma pharmacies. Kudzisankhira pawokha sikuphatikizidwa.
Kupita kwina mankhwala
Mtundu uliwonse wamasulidwe ukupezeka pamankhwala.
Mtengo wa Etamsilat
Mtengo wamankhwala (kutengera mtundu wa kumasulidwa) umayamba kuchokera ku ma ruble 120.
Kusunga mankhwala Ethamsylate
Mankhwalawa amayenera kusungidwa pamalo apadera komanso ozizira. Kuwonetsedwa ndi dzuwa kuyenera kupewedwa. Ndi zoletsedwa konse kuloleza ana ndi ziweto zawo kumalo osungira mankhwalawo.
Tsiku lotha ntchito
Sizoletsedwa kusunga mankhwalawa (mosasamala mtundu wa mlingo) kwa miyezi yopitilira 36.
Ndemanga za Ethamsilate
Vladimir Starovoitov, dokotala wa opaleshoni, Nizhny Novgorod
Ndimaona kuti mankhwalawa ndi othandiza. Pochita, ndimalembetsa kwa nthawi yayitali. Mtengo wa mankhwalawo ndi wocheperako, womwe umathandizira kupeza mawonekedwe a mtundu uliwonse ndikupangitsa kuti mankhwalawo akhale okwera magawo onse a anthu. Nthawi zambiri ndimaphatikizanso hemostatic pakukonzanso monga njira yolepheretsa kutaya magazi pambuyo pakuchita opaleshoni.
Ndikupangira kuti odwala anga azitha kumwa osachepera maola 1.5-2 maola asanachitike. Munthawi imeneyi, mankhwalawa atamwa kwathunthu, amayamba kuchita theka la ola mukatha kugwiritsa ntchito. Mankhwala amachepetsa ngozi ya capillary ndi venous magazi. Imagwira makamaka ngati gawo la zovuta mankhwala.
Madandaulo okhudzana ndi zovuta kuchokera kwa odwala ndi ochepa. Cholinga chachikulu chomwe chitha kuchitika ndikuwonjezereka mosaloleka kwa mlingo womwe dokotala wakhazikitsa. Zotsatira zoyipa nthawi zambiri zimadalira pakatha masiku awiri ndi atatu.
Larisa, wazaka 31, Magnitogorsk
Mwana wosabadwayo amayamba kuyamwa patatha milungu 16. Pambuyo poyeretsa, magazi anatseguka. Pambuyo pa kufufuza, adokotala adalandira jakisoni wa mankhwala ena a antihemorrhagic. 1 jakisoni sizinathandize, ndinayenera kubaya maphunzirowa. Kutulutsa magazi kunayimitsidwa, mankhwalawo adalowetsedwa kunyumba masiku ena asanu. Pambuyo pa opareshoni, kusamba kwa msambo kunasokonekera. Kutulutsa kumakhala kochulukirapo, panthawi yomwe akusamba adayamba kumva kuti ali ndi chizungu komanso kufooka. Apanso ndinapita kwa azachipatala. Dotoloyo adati kuchepa kwa magazi ndikulimba, ndikofunikira kuti magazi azithamanga mofulumira.
Anatenga mankhwala oledzera monga mapiritsi. Kumayambiriro kwa mankhwalawa, amamwa piritsi limodzi katatu patsiku, ndikukulitsa pang'onopang'ono mapiritsi 2 kamodzi. Dokotalayo anachenjeza kuti ndizosatheka kusiya kudya mwachangu, ndikofunikira kuti muchepetse pang'onopang'ono. Zotsatira zoyipa zinaonekera patsiku lachiwiri la chithandizo. M'mawa nditamwa mapilitsi, ndinamva kugunda kwambiri.
Pa nkhomaliro, phwando linaganiza kuti asaphonye, ndinamwa piritsi nditatha kudya. Panalibe mseru, koma panali kupweteka pang'ono, komwe kunapita patapita maola ochepa. Masiku oyamba sakanatha kugona kwa nthawi yayitali, ndiye kuti kugona kumakhala kwachibadwa.
Maxim, wazaka 43, Astrakhan
Hemophilia wadwala kwanthawi yayitali. Kuti mukhale ndi thanzi labwino, amakakamizidwa kumwa mankhwala a anti-hemorrhagic pafupipafupi. M'mbuyomu, adapewa mankhwala azikhalidwe, adayesetsa kudzipulumutsa pogwiritsa ntchito wowerengeka, koma zidangokulira. Pambuyo pa kupangana kotsatira, adotolo adalangiza kuti atenge mankhwala okwera mtengo okhala ndi hemolytic. Chifukwa chokhala ndi mavuto azachuma, ndimangomwa mankhwala amodzi okha. Adokotala andifunsa kuti ndisankhe chida chotsika mtengo kwambiri.
Chisankhochi chidayimitsidwa pamtengo wotsika mtengo womwe umapangidwanso monga mankhwala okwera mtengo. Ndinagula mankhwalawo ku pharmacy ndi mankhwala. Choyamba ndimatenga piritsi limodzi 2 kawiri patsiku, ndiye, mwachilolezo kwa adotolo, ndidakulitsa pang'ono. Ndikufuna kudziwa kuti mphamvu ya hemolytic ya mankhwalawa ikupitilira. Mwa zaka zonse zogwiritsidwa ntchito, zoyipa zimachitika nthawi 1 chifukwa cha kayendetsedwe kosayenera. Mankhwalawa sayenera kuledzera pamimba yopanda kanthu: nseru ikuwoneka. Ndimamwa mapiritsi a masabata awiri ndikupumula kwa masiku 6-7. Kukhutitsidwa ndi zotsatira zake.
