Liptonorm ndi mankhwala ochepetsa mphamvu ya lipid omwe ali m'gulu la ma seins. Kuchita kwa mankhwalawa ndikulepheretsa zochitika za HMG-CoA reductase, enzyme yomwe imapangitsa kutembenuka kwa HMG-CoA kukhala mevalonic acid. Enzyme imathandizira gawo loyambirira la cholesterol kupanga.
Gawo lalikulu limalepheretsa kupanga cholesterol, chifukwa chomwe receptor reacaction ya LDL (low density lipoproteins) imachulukana.
Izi zimachitika mu minyewa yowonjezera komanso mwachindunji mkati mwa chiwindi. Chifukwa chake, cholesterol m'mwazi imachepetsedwa ndikumangirira ndikuwuchotsa ku plasma.
Komanso, mapiritsi amatha kukhala ndi anti-atherosulinotic.
Zigawo za mankhwala zimatha kukhala ndi zotsatirazi mthupi:
- linalake ndipo tikulephera ntchito ya isoprenoids ndi kaphatikizidwe;
- amalimbikitsa vasodilation;
- amachepetsa cholesterol, triglycerides, apoliproteins B, LDL;
- imachulukitsa kuchuluka kwa apoliprotein A ndi "opindulitsa" cholesterol.
Miyezi makumi asanu atatha kuyamba kwa chithandizo chamankhwala, mutha kuwona zomwe zikuchitika panthawi ya matendawa. Kuti mukwaniritse kwambiri, mokhazikika pamachitika mwezi uliwonse mwezi uliwonse. Maphunzirowa amathandizira kuchepetsa thupi mwakuchepetsa cholesterol "yoyipa".
Mankhwalawa amamwetsedwa bwino, kuchuluka kwake kwa mankhwalawa kumawonedwa pambuyo pa maola 2 mutatha kugwiritsa ntchito. Mwa akazi, kuchuluka kwa mankhwalawa nthawi zambiri kumakhala kokwanira kuposa 20% kuposa amuna.
Thupi limapukusidwa mu nthawi ya chiwindi kagayidwe kachakudya. Kuchoka kumachitika mkati mwa maola 14, ndipo zotsatira za mankhwalawa zimawonedwa kwatha maola 20 pambuyo pa kuperekedwa. Pa hemodialysis, yogwira pophika sachotsedwa m'thupi. Mkodzo wa wodwalayo sungapulumutse kupitirira 2% ya mlingo womwe umamwa.
Monga mankhwala onse, Liptonorm ili ndi malingaliro ake ogwiritsira ntchito.
Ndi dokotala yekhayo amene angakupatseni mankhwala, potengera mawonekedwe ake komanso momwe zinthu zilili m'thupi.
Kugwiritsa ntchito mankhwalawa pakudzipatsa nokha mankhwala ndizoletsedwa.
Mapiritsi amalembedwa:
- Homozygous ndi heterozygous lipocholesterolemia. Mankhwalawa nthawi zambiri amathandizidwa ndi mankhwala othandizira.
- Hyperlipidemia wosakanikirana.
- Hyperlipidemia yoyamba.
Zolemba za mankhwalawa zimatha kusokoneza thanzi pamaso pazinthu zina. Zikatero, simungatenge.
Zopanda malire kwathunthu zimaphatikizapo:
- kulephera kwa chiwindi;
- matenda enaake a chiwindi oyambira osiyanasiyana;
- matenda owopsa a chiwindi, komanso mitundu ya matenda a chiwindi;
- kukhalapo kwa kuchuluka kwa ntchito kwa hepatic transaminase yachidziwitso osadziwika;
- odwala osakwana zaka 18;
- nthawi yobereka mwana ndi yoyamwitsa;
- kusalolera kwa thupi la zigawo zikuluzikulu za mankhwala.
Nthawi zina, kugwiritsa ntchito mankhwalawa kumatheka pokhapokha kuyang'aniridwa ndi dokotala.
Contraindative zokhudzana ndi izi:
- Kukhalapo kwa matenda a chiwindi.
- Electrolyte kusalinganika.
- Zovuta za endocrine dongosolo ndi kagayidwe kachakudya njira.
- Njira yodalira yakumwa.
- Kukhalapo kwa matenda oyambitsidwa ndi matenda.
- Kumachitika kwa kulanda kosalamulirika.
- Kukhalapo kwa ovulala kwambiri.
- Opaleshoni.
Chithandizo cha mankhwala ngati ichi chimasankhidwa ndi katswiri woyenera yekha yemwe amadziwa bwino momwe wodwalayo alili.
Chogulacho chimapezeka ngati mapiritsi mu chipolopolo. Piritsi lililonse limakhala ndi yogwira, calcium atorvastatin. Mapiritsi amapezeka mu 20, kapena 10 mg. Mapaketi amatha kukhala ndi mbale 1 mpaka 4, iliyonse ya mapiritsi 7, 14 ndi 10.
Asanapereke mankhwala amenewo, wodwalayo amasinthidwa kuti azidya zakudya zabwino, zomwe zimapangitsa kuchepa kwa milingo ya lipid. Zakudya zotere ziyenera kuchitika nthawi yonse ya chithandizo.
Malinga ndi malangizo, muyenera kumwa mapiritsi kamodzi patsiku, kugwiritsa ntchito mankhwalawa sikudalira chakudya. Muyenera kumwa tsiku lililonse nthawi yomweyo.
Choyamba, adokotala amakhazikitsa mlingo - 10 mg. Kupitilira apo, mulingo woyenera kwambiri umaganizira za munthu payekha - zomwe zili mu LDL m'magazi ndi matendawo. Komanso, mlingo umatsimikiziridwa potengera mphamvu ya mankhwalawa.
Mlingo wapamwamba ndi 80 mg. Katswiri woyenera amayenera kupereka mlingo, ndizoletsedwa kugwiritsa ntchito mankhwalawa pakudzipaka nokha.
Mu phukusi lililonse la mankhwala Liptonorm pali malangizo ogwiritsira ntchito. Mtengo wa mankhwala umasiyanasiyana pang'ono kutengera gawo lomwe wagulitsa mankhwalawo. Nthawi zambiri, ndemanga zabwino zimapezeka pamankhwala awa.
Mtengo wa mankhwalawa ku Russian Federation uli mu 275-319 rubles. Kugula mankhwala kungachitike ndi mankhwala.
Zotsatira zoyipa za mankhwalawa
Mankhwala amtunduwu sioyenera aliyense. Chifukwa cha mphamvu yake, ili ndi zovuta zingapo.
Zotsatira zoyipa za mankhwalawa zimadziwonetsera payokha.
Kuchokera kumbali yamanjenje yapakati, kusokonezeka kwa tulo ndi chizungulire nthawi zambiri kumatha kuwonedwa, kuchepa kwambiri, kulimbitsa thupi, kupweteka mutu, kusazindikira, kupsinjika, kuiwala kukumbukira, kufooka kwamitsempha yama nkhope, kuchepa kwa mitsempha komanso kufooka kwa magawo azinthu.
Kumbali yamitsempha yamagazi, kupweteka pachifuwa, migraines, kuthamanga kwa magazi, arrhythmia, angina pectoris, phlebitis ndi palpitations a mtima nthawi zambiri zimawonedwa.
Kumbali yamalingaliro am'maganizo, kuphwanya kwamphamvu kwa kukoma ndi kununkhira kumapezeka, kupezeka pang'ono kapena kusamva kwathunthu, ndipo nthawi zina matenda a shuga, magazi ammaso ndi amblyopia amakula.
Pa gawo la chakudya cham'mimba, pakamwa pouma, stomatitis, komanso kutulutsa magazi m'magazi. Zilonda zam'minyewa zamkamwa, kupweteka pafupipafupi, kusefukira, kukhumudwa, nseru, kusokonezeka, kusanza, esophagitis, melena, zilonda, kapamba, chiwindi, jaundice ndi hepatitis.
Ziwalo zopumira - bronchitis ndi rhinitis nthawi zambiri zimawonedwa. Chomwe chimakonda kwambiri kukha magazi kuchokera pamphuno, mphumu ya bronchial ndi chibayo.
Musculoskeletal system - nyamakazi imakonda kuoneka, kukokana kawirikawiri, myositis, minofu hypertonicity ndi myalgia.
Kuchokera pa hematopoietic dongosolo, kukulitsa kwa lymphadenopathy, thrombocytopenia ndi kuchepa kwa magazi m'thupi la shuga kumatheka.
Genitourinary dongosolo - pafupipafupi mawonetseredwe a matenda a urogenital ndi zotumphukira edema. Zocheperako, zotsatira zoyipa zimawonetsedwa mu nephrourolithiasis, dysuria, hemorrhage, kusabala, kuchepa kwa kugonana, nephritis, kukomoka kwa chiwindi ndi metrorrhagia.
Thupi lawo silitha kuwoneka ngati zotupa pakhungu, kuyabwa kwambiri ndi dermatitis. Zochepa zomwe zimachitika ndi anaphylaxis, kutupa kwa nkhope, urticaria, matenda a Stevens-Johnson.
Mawonekedwe a dermatological nthawi zambiri amakhala mu mawonekedwe a alopecia, thukuta kwambiri, eczema, xeroderma, petechiae.
Kulemera kungawonedwe, kapena mosinthanitsa, wodwalayo amatha kuchepa thupi, matenda a gynecomastia komanso kufalikira kwa gout angayambike ngati wodwala ali nako.
Ngakhale zili ndi zovuta zake, mapiritsiwa ndi othandiza komanso osawunika kamodzi.
Ndi bongo wambiri, mawonetsero ena angapo ndi otheka. Pakati pawo, mutha kuwona zofanana ndi zovuta, zomwe zimangotchulidwa.
Wodwala kwambiri ayenera:
- pewani kuyamwa kwa mankhwala ena, potenga makala ndi kutsuka m'mimba;
- thandizirani ntchito za ziwalo zofunika pamoyo;
- kuthetsa malingaliro owonetsera.
Kusakwanira kwa hemodialysis pankhaniyi kumatsimikiziridwa.
Pa mankhwala, wodwala amafunikira kuyang'aniridwa nthawi zonse. Ndikofunikira kuwongolera ntchito ya ziwalo ndi zothandizira zamankhwala. Ngati pali kusintha kwachilengedwe, siyani kapena muchepetse mlingo wa mankhwalawo.
Pa gawo loyambirira la kumwa mankhwalawa komanso munthawi yowonjezera Mlingo, muyenera kuyang'anira ntchito ya chiwindi ikuyang'aniridwa. M'miyezi itatu yoyamba kumwa mankhwalawa, pali kusokonezeka pang'ono kwa ntchito ya thupi. Ngati pali kuphwanya kwakukulu kwazonse, njira yochiritsira iyenera kusiyidwa.
Ngati wodwala wayambitsa matenda a myalgia kapena kufooka kwa minofu, mankhwalawo ayenera kusiyidwa.
Pankhani yakuphwanya chiwindi, muyenera kusamala kuti mutenge.
Kumwa mankhwala ali contraindicated matenda otere:
- matenda a chiwindi;
- yogwira nthawi ya matenda a chiwindi;
- kulephera kwa chiwindi.
Pa mankhwala, muyenera kusiya kugwiritsa ntchito madzi a mphesa, zimathandizira kuwonjezera kuchuluka kwa atorvastatin m'magazi.
Ngati Liptonorm imatengedwa limodzi ndi cyclosporine, Erythromycin, ndi immunosuppressants, kuchuluka kwa magazi a atorvastatin kumatha kuwonjezeka, zomwe zimapangitsa kuti myopathy ipezekenso. Kuvomerezedwa kwa maantacidus kumachepetsa kuchuluka kwa mankhwalawo ndi 35 peresenti.
Mankhwala omwe amatha kusintha m'malo mwa Liptonorm ali ndi zotsutsana zomwezo, zikuwonetsa komanso mavuto. Amasiyana pamtengo. Mapiritsi amatha kusintha:
- Atorvastatin - mtengo ku Russia ndi wochokera pa ma ruble 126.
- Anvistatom - mtengo ku Russia - kuchokera 210 rubles.
- Atoris - mtengo ku Russia - kuchokera 426 rubles.
- Liprimar ndi analogue yotsika mtengo komanso mtengo ku Russia kuchokera ku 2500 rubles.
- Torvakard - mtengo ku Russia uchokera ku 499 rubles.
Mankhwala aliwonse amathanso kuikidwa ndi katswiri woyenera, popeza zinthuzo zimakhala ndi mphamvu kwambiri mthupi ndipo ngati zalembedwa molakwika, zingayambitse zovuta zambiri.
Momwe mungachepetse cholesterol yamagazi ikufotokozedwa mu kanema m'nkhaniyi.
