Ndi mankhwala ozikidwa ndi insulin yaumunthu. Kugwiritsidwa ntchito ndi odwala omwe ali ndi matenda a shuga.
Dzinalo Losayenerana
Mankhwala a Monoinsulin ndi anthu, m'Chilatini - Insulin Human.
Monoinsulin ndi mankhwala ozikidwa ndi insulin ya anthu.
ATX
A.10.A.B.01 - Insulin (munthu).
Kutulutsa mafomu ndi kapangidwe kake
Imapezeka mu mawonekedwe a jakisoni wopanda mtundu, wowoneka bwino, wobayira m'mabotolo agalasi (10 ml), omwe amaikidwa m'bokosi lamkatoni (1 pc.).
Njira yothetsera vutoli ili ndi chigawo chogwira ntchito - ma genetic mwanjira yaumunthu insulin (100 IU / ML). Glycerol, madzi a jakisoni, metacresol ndi zina zowonjezera zamankhwala.
Zotsatira za pharmacological
Mankhwalawa ndiwofupikitsa anthu omwe amapanga insulin. Zimathandizira kutulutsa matenda a shuga, zimawonetsa zotsatira za anabolic. Kulowa minofu minofu, imathandizira kayendedwe ka amino acid ndi glucose pama cellular; protein anabolism imayamba kutchulidwa.
Mankhwalawa amathandizira glycogenogeneis, lipogenesis, amachepetsa kuchuluka kwa shuga ndi chiwindi, komanso amathandizira kukonza kwa glucose owonjezera m'mafuta.
Monoinsulin amathandizanso kuti kagayidwe kazigawo azigwiritsa ntchito.
Pharmacokinetics
Mafuta ndi mawonekedwe a yogwira ntchito zimatengera zinthu zingapo:
- njira yolowera thupi - kudzera m'mitsempha kapena mozungulira, kudzera m'mitsempha;
- kuchuluka kwa jakisoni;
- madera, malo oyambitsa thupi - matako, ntchafu, phewa kapena pamimba.
Pamene p / mu ntchito ya mankhwala kumachitika pafupifupi 20-30 Mphindi; mphamvu pazipita zimawonedwa mkati 1-3 maola. Kutalika kwa kuchitapo kumatenga pafupifupi maola 8-10. Kugawa mu minofu sikofanana.
Chithandizo chogwiritsa ntchito sichilowa mkaka wa mayi woyamwitsa ndipo sichidutsa mwa placenta.
Kuwonongeka kwa mankhwalawa kumachitika mchikakamizo cha insulinase mu impso, chiwindi. Hafu ya moyo ndiyifupi, imatenga mphindi 5 mpaka 10; excretion wa impso ndi 30-80%.
Zizindikiro zogwiritsidwa ntchito
Amalembera odwala matenda a shuga kuti wodwala azitha kulandira mankhwala a insulin, komanso odwala matenda ashuga apezeka. Chizindikiro chogwiritsira ntchito ndi osachiritsika omwe amadalira shuga II panthawi yapakati.
Contraindication
Mwa zomwe akuphwanya mankhwala, dziwani:
- kusalolera kwa aliyense kwa chigawo chimodzi ndi insulin;
- hypoglycemia.
Makamaka chidwi chake chimayenera kuperekedwa kwa azimayi omwe ali ndi trimester yoyamba, kufunika kwa insulin kumachepetsedwa.
Kodi kumwa monoinsulin?
Zimayambitsidwa m'thupi m'mafuta, s / c, in / in; Mlingo umatengera shuga m'magazi. Anthu omwe amadya tsiku lililonse ndi 0,5-1 IU / kg kulemera kwa munthu, potengera mawonekedwe amunthu.
Inayambitsidwa musanadye (chakudya) kwa theka la ola. Onetsetsani kuti yankho la jakisoni liyenera kukhala kutentha kwambiri. Njira yofananira yoperekera mankhwalawa ndiyosamveka m'dera la khomo lakumaso. Izi zimathandizira kuyamwa mwachangu kwa mankhwalawa.
Ngati jekeseni wayikidwa m'khola la khungu, chiopsezo chovulala minofu chichepe.
Ndi kugwiritsa ntchito mankhwalawa pafupipafupi, malo omwe amayikidwapo amayenera kusintha kuti aletse lipodystrophy. Jakisoni wamkati ndi intramuscular ndi insulin imaperekedwa ndi wothandizira zaumoyo.
Zotsatira zoyipa za monoinsulin
Hypoglycemia ndi imodzi mwazinthu zosasangalatsa zomwe zimachitika nthawi ya insulin. Zizindikiro zimawonekera ndikukula msanga:
- blanching, nthawi zina cyanosis wa pakhungu;
- thukuta;
- Kuda nkhawa
- kunjenjemera, mantha, chisokonezo;
- kutopa;
- kumverera kwanjala yayikulu;
- chizungulire pafupipafupi;
- hyperemia;
- kulumikizidwa kolakwika, kuyang'ana m'malo;
- tachycardia.
Hypoglycemia yayikulu imatsatiridwa ndi kusazindikira, nthawi zina machitidwe osasintha amasintha mu ubongo, imfa imachitika.
Monoinsulin imatha kuyambitsa ziwengo zakomweko momwe zimayambira ndikusokosera.
Mankhwalawa atha kuyambitsa chifuwa cham'deralo m'njira yotupa, redness, kuyabwa m'dera la jakisoni wangwiro, yemwe amadutsa palokha.
Zimakhala zovuta kwa odwala kuti azilimbana ndi mavuto ambiri am'mimba komanso kusokonezeka kwam'mimba, kupuma movutikira, kukwiya kwambiri, matenda pamalo a jekeseni, ochepa hypotension, tachycardia, angioedema. Pankhaniyi, chithandizo chapadera chikusonyezedwa, kusintha kwa mankhwala kwa yogwira.
Zokhudza mphamvu pakuwongolera njira
Hypoglycemia, hyperglycemia imatha kuyambitsa chidwi champhamvu, chomwe, chimakhala chowopsa kwa amene akuyendetsa galimoto, maginito akuluakulu ndi misonkhano yayikulu.
Anthu omwe amamwa mankhwalawa amayenera kupewa kuyendetsa galimoto ngati zingatheke.
Malangizo apadera
Ndi kugwiritsidwa ntchito kosalekeza kwa yankho la insulin, shuga wa m'magazi amayang'aniridwa. Nthawi zina, ndikusokonekera kwambiri pakukhudzika ndi kusowa kwa thandizo, matenda ashuga a ketoacidosis amatha kuchitika pambuyo pake.
Ngati chithokomiro cha chithokomiro, impso kapena chiwindi chimasokonekera, matenda a Addison amadziwika, Mlingo wa mankhwalawa umasinthidwa. Ndi matenda opatsirana ofanana, zovuta za thupi, thupi liyenera kuwonjezera kuchuluka kwa insulini yoyendetsedwa. Mlingo womwe ungatheke umasintha ndikusinthanso kwa chakudya, kuchuluka kwa mphamvu zolimbitsa thupi.
Gwiritsani ntchito mu ukalamba
Kwa odwala atatha zaka 65, mlingo wa insulin yothetsera umachepetsedwa - zonse zimatengera zizindikiro za glucose, zomwe zimayenera kuyang'aniridwa pafupipafupi.
Monoinsulin imaloledwa panthawi yomwe ali ndi pakati, sizowopseza moyo ndi thanzi la mwana wosabadwayo.
Kupatsa ana
Zotheka kumwa mankhwalawa kwa ana, achinyamata sanaphunzire.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Mankhwala sangathe kudutsa chotchinga. Chifukwa chake, kuvomereza kwake panthawi yomwe ali ndi pakati kumaloledwa, sizikuwopseza moyo ndi thanzi la mwana wosabadwayo.
Palibe chowopsa kwa mwana, monga chogwira ntchito sichilowa mkaka wa m'mawere. Munthawi imeneyi, kuyang'aniridwa kosalekeza kwama glucose kunawonetsedwa. Pambuyo pobereka, mtundu wa 1 wa matenda a shuga umachitika motsatira ndondomeko, ngati thanzi silikuipa komanso kusinthanso kwa mlingo sayenera.
The ntchito aimpso kuwonongeka
Ngati kulephera kwa impso kwapezeka, kufunikira kwa mankhwalawa kumatha kuchepa kwambiri, motero, mlingo wake wokhazikika umachepetsedwa.
Kulephera kwa chiwindi nthawi zambiri kumayambitsa kuchepa kwa mlingo wa Monoinsulin.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Kulephera kwa chiwindi nthawi zambiri kumayambitsa kuchepa kwa mankhwala.
Monoinsulin Overdose
Ngati mulingo wovomerezeka wa insulin utaperekedwa, hypoglycemia ndiyotheka kukulira. Ndi mtundu wofatsa wa matenda, munthu amadzilimbitsa yekha pakudya zakudya zamafuta ambiri, shuga. Pazifukwa izi, odwala matenda ashuga nthawi zonse amakhala nawo ndimadziti okoma, maswiti.
Ngati kwambiri hypoglycemia, wodwalayo amapatsidwa mwachangu iv solution ya shuga (40%) kapena glucagon mwanjira iliyonse yosavuta - iv, s / c, v / m. Mkhalidwe wabwinobwino ukakhala wabwinobwino, munthu ayenera kudya zakudya zopatsa mphamvu kwambiri, zomwe zimathandiza kuti asayambenso kudwala.
Kuchita ndi mankhwala ena
Mphamvu ya hypoglycemic imakhala yochepa kwambiri ikaphatikizidwa ndi corticosteroids, kulera kwapakamwa, ma tridclic antidepressants, mahomoni a chithokomiro, ndi thiazolidinediones.
Mphamvu ya hypoglycemic imapangidwira ndi sulfonamides, salicylates (salicylic acid, mwachitsanzo), Mao inhibitors, ndi othandizira a hypoglycemic pokonzekera pakamwa.
Zizindikiro za hypoglycemia zimaphimbidwa ndipo zimawoneka pang'onopang'ono pankhani ya mgwirizano wa clonidine, beta-blockers, reserpine.
Kuyenderana ndi mowa
Kugwiritsidwa ntchito kwa ethanol (mankhwala okhala ndi ethanol) omwe ali ndi insulin kumawonjezera zotsatira za hypoglycemic.
Analogi
Insuman Rapid GT, Actrapid, Humulin Regular, Gensulin R.
Kupita kwina mankhwala
Mankhwala amagulitsidwa mosamala ndi mankhwala.
Kodi ndingagule popanda kulandira mankhwala?
Palibenso mwayi wotsatsa wogula mankhwala othandizira odwala matenda ashuga.
Mtengo
Mtengo wa mankhwala omwe amapangidwa ku Belarus ku Russia ndi pafupifupi ma ruble 250.
Zosungidwa zamankhwala
Mankhwalawa amayenera kusungidwa pamalo amdima pofotokozera chizindikiro cha + 2 ... + 8 ° C; kuzizira kwa yankho sikuvomerezeka.
Tsiku lotha ntchito
Zaka 2,5.
Wopanga
RUE Belmedpreparaty (Republic of Belarus).
Actrapid ndi analogue ya Monoinsulin.
Ndemanga za akatswiri azachipatala
Elena, endocrinologist, wazaka 41, Moscow
Mankhwala awa ndi analogue a insulin ya anthu. Pewani hypoglycemia kumangowonjezera kudya kolondola kwa mankhwalawo, kutsatira kwambiri mankhwala ndi zakudya.
Victoria, dokotala wazaka wazaka 32, Ilyinka
Type 1 shuga mellitus ndikugwiritsa ntchito insulini nthawi zonse zimakhudza kusamba kwa msambo (zovuta zake, kusakhalapo kwathunthu) zitha kuonedwa. Ngati mukufuna kukhala ndi pakati podziwitsa za matendawa, muyenera kufunsa dokotala wazachipatala yemwe angakuthandizeni kuthetsa vutoli.
Ndemanga za Odwala
Ekaterina, wa zaka 38, Perm
Abambo anga ali ndi matenda ashuga odziwa zambiri. Tsopano ndinayamba kumwa insulin ya ku Belarusi. Mwina chifukwa cha kusintha kwokhudzana ndi zaka, kapena chifukwa cha mawonekedwe a mankhwalawo, koma adotolo adamuchepetsa.
Natalia, wazaka 42, Rostov-on-Don
Ndinazindikira kuti ndinayamba kudwala matenda ashuga mwadzidzidzi, pomwe ndinadwala kwambiri kuchipatala. Ma jakisoni a Monoinsulin mu mlingo wocheperako adafotokozera. Ndakhala ndikugwiritsa ntchito kwa nthawi yoposa chaka, poyamba ndimachita mantha ndi zovuta, koma zonse zili bwino, ndikumva bwino.
Irina, wazaka 34, Ivanovsk
Kwa ine, vuto lalikulu ndikugula mankhwala nthawi zonse mtawuni yaying'ono. Ndinayesa kufananiza kupanga zoweta, koma sizinayenere, thanzi langa limakulirakulira.
