Matenda a 2 a shuga amatengedwa ngati matenda a metabolism omwe amadziwika ndi kukula kwa hyperglycemia chifukwa cha kusokonekera kwa maselo amthupi ndi insulin.
Kuti achepetse kuchuluka kwa glucose omwe ali m'magazi, odwala ena, kuphatikizapo zakudya zamagulu ena, amafunikira mankhwala ena.
Chimodzi mwazo mankhwalawa ndi glurenorm.
Zambiri, kapangidwe ndi mawonekedwe ake amasulidwe
Glurenorm ndi nthumwi ya sulfonylureas. Ndalamazi zimapangidwa kuti muchepetse magazi.
Mankhwalawa amalimbikitsa katemera wa yogwira insulin ndi maselo a kapamba, omwe amathandiza kuyamwa shuga wambiri.
Mankhwala amathandizidwa ndi odwala omwe amadya zakudya osapatsa mphamvu, ndipo njira zina zimafunikira kuti zikhale zovuta kuzindikiritsa magazi.
Mapiritsiwo ndi oyera pamtundu, ali ndi zolemba "57C" ndi logo yogwirizana ndi wopanga.
Zopangidwa:
- Glycvidone - gawo lalikulu yogwira - 30 mg;
- wowuma chimanga (wouma ndi sungunuka) - 75 mg;
- lactose (134.6 mg);
- magnesium stearate (0.4 mg).
Phukusi la mankhwala limatha kukhala ndi mapiritsi 30, 60, kapena 120.
Pharmacology ndi pharmacokinetics
Kumwa mankhwalawa kumayambitsa zotsatirazi kagayidwe kachakudya mthupi:
- m'maselo a beta cholumikizira kukwiya ndi shuga amachepetsa, zomwe zimapangitsa kupanga kwa insulin kwambiri;
- kudziwa kwa zotumphukira maselo kwa mahomoni ukuwonjezeka;
- katundu wa insulin amawonjezera kuchititsa mayamwidwe a chiwindi ndi glucose;
- lipolysis yomwe imachitika minofu ya adipose imachedwa;
- kuchuluka kwa glucagon m'magazi kumachepa.
Pharmacokinetics:
- Kuchita kwa zigawo zikuluzikulu za wothandizirazi kumayamba patatha pafupifupi ola limodzi ndi 1.5 kuchokera nthawi yomwe munthu wakumwa. Zochitika zochuluka za zinthu zomwe zimaphatikizidwa pokonzekera zimatha maola atatu, ndipo maola ena 12 atsalira.
- Kagayidwe ka zigawo zikuluzikulu za mankhwala kumachitika makamaka mu chiwindi.
- Kuchotsa zigawo zikuluzikulu za mankhwalawa kumachitika kudzera m'matumbo ndi impso. Hafu ya moyo ili pafupifupi maola awiri.
Magawo a kinetic a mankhwalawa sasintha akagwiritsidwa ntchito ndi okalamba, komanso odwala omwe ali ndi vuto la matenda a impso.
Zizindikiro ndi contraindication
Glurenorm imagwiritsidwa ntchito ngati mankhwala oyenera omwe amagwiritsidwa ntchito pochiza matenda a shuga a 2. Nthawi zambiri, mankhwalawa amaperekedwa kwa odwala akafika zaka zapakati kapena zokhala ndi zaka zapakati, pamene glycemia sangakhale yofanana ndi chithandizo cha mankhwala.
Zoyipa:
- kukhalapo kwa matenda a shuga 1;
- kuchira pambuyo pambuyo pancreatic resection;
- kulephera kwaimpso;
- zosokoneza mu chiwindi;
- acidosis yomwe idapangidwa poyambira shuga;
- ketoacidosis;
- chikomokere (choyambitsidwa ndi matenda ashuga);
- galactosemia;
- lactose tsankho;
- matenda opatsirana omwe amapezeka m'thupi;
- othandizira opaleshoni;
- mimba
- ana ochepera zaka zambiri;
- tsankho ku zigawo zikuluzikulu za mankhwala;
- nthawi yoyamwitsa;
- matenda a chithokomiro;
- uchidakwa;
- pachimake porphyria.
Malangizo ogwiritsira ntchito
Glurenorm imatengedwa pakamwa. Mlingo wa mankhwalawa umakhazikitsidwa ndi adokotala atatha kuwunika momwe wodwalayo alili, kupezeka kwa matenda olimba ndi njira zotupa.
Panthawi yomwe mumamwa mapiritsi, muyenera kutsatira zakudya zopatsa mphamvu zomwe zimaperekedwa ndi endocrinologist ndi regimen yokhazikitsidwa.
Muyenera kuyamba kulandira chithandizo chochepa ndi mapiritsi a 0,5. Mankhwala oyamba amatengedwa nthawi ya chakudya cham'mawa.
Ngati palibe phindu kuchokera pakumwa theka la piritsi, muyenera kufunsa dokotala, monga momwe kuchuluka kungafunikire kungafunike. Palibe mapiritsi oposa 2 omwe amaloledwa patsiku. Pakuchitika kwa hypoglycemic, odwala sayenera kuwonjezera mlingo wa Glyurenorm, koma tengani Metformin pambuyo povomerezana ndi adokotala.
Malangizo apadera
Mankhwala othandizira odwala matenda ashuga ayenera kuchitika kokha moyang'aniridwa ndi dokotala.
Odwala sayenera kusintha kuchuluka kwa mankhwalawa, komanso kusiya kulandira mankhwalawo kapena kusinthira ku kutenga mankhwala ena a hypoglycemic popanda kuvomerezedwa ndi endocrinologist.
Malamulo apadera ovomerezeka omwe akuyenera kusungidwa:
- kuwongolera thupi;
- osadumpha chakudya;
- kumwa mapiritsi pokhapokha pa kadzutsa, osati pamimba yopanda kanthu;
- konzekerani zolimbitsa thupi;
- kupatula kugwiritsa ntchito mapiritsi okhala ndi vuto la shuga-6-phosphate dehydrogenase;
- lingalirani machitidwe a zopsinjika pazovuta za glucose, komanso mowa.
Odwala omwe ali ndi vuto la impso komanso matenda a chiwindi ayenera kuyang'aniridwa ndi akatswiri panthawi yamankhwala. Mitundu yovuta kwambiri ya kukanika kwa chiwindi imawonedwa ngati kuphwanya kugwiritsidwa ntchito kwa Glyurenorm chifukwa chakuti zigawo zake zimapangidwira mu chiwalochi.
Kutsatira malangizowa kumathandizira wodwala kupewa kukula kwa hypoglycemia. Maonekedwe amtunduwu amaonedwa ngati owopsa kwambiri panthawi yomwe mukuyendetsa, pamene ndizovuta kuchitapo kanthu kuti muchepetse zizindikirazo. Odwala omwe amagwiritsa ntchito Glurenorm ayenera kuyesa kupewa kuyendetsa, komanso njira zosiyanasiyana.
Pa nthawi yoyembekezera, komanso yoyamwitsa, amayi ayenera kusiya kugwiritsa ntchito mankhwala osokoneza bongo. Izi ndichifukwa chakusowa kwazofunikira pakuwongolera zomwe zimagwira pakukonzekera kwa mwana. Ngati ndi kotheka, kufunikira kwa mankhwala ochepetsa shuga kwa amayi oyembekezera kapena oyembekezera akuyenera kusinthira ku insulin.
Zotsatira zoyipa ndi bongo
Kumwa mankhwalawa kumadzetsa zotsatirazi zina mwa odwala ena:
- za hematopoietic dongosolo - leukopenia, thrombocytopenia, agranulocytosis;
- hypoglycemia;
- kupweteka mutu, kutopa, kugona, chizungulire;
- kuwonongeka kwamawonekedwe;
- angina pectoris, hypotension ndi extrasystole;
- Kuchokera m'mimba dongosolo - nseru, kusanza, kukhumudwa, cholestasis, kusowa chilolezo;
- Stevens-Johnson syndrome;
- urticaria, zotupa, kuyabwa;
- kupweteka kumamveka m'chifuwa.
Mankhwala osokoneza bongo amatsogolera ku hypoglycemia.
Pankhaniyi, wodwalayo amamva chizindikiro cha mkhalidwe:
- kumverera kwa njala;
- tachycardia;
- kusowa tulo
- thukuta;
- kugwedezeka
- kusokonekera kwa mawu.
Mutha kuyimitsa chiwonetsero cha hypoglycemia potenga zakudya zopatsa mphamvu mkati. Ngati munthu sakhudzidwa pakadali pano, ndiye kuti kuchira kwake kumafunika shuga mkati. Pofuna kupewa kubwereza kwa hypoglycemia, wodwalayo ayenera kukhala ndi zina zowonjezera pambuyo pobayidwa.
Kuyanjana Ndi Mankhwala Ndi Analogi
Mphamvu ya hypoglycemic ya Glenrenorm imatheka chifukwa chogwiritsika ntchito munthawi yomweyo ngati mankhwalawa:
- Glycidone;
- Allopurinol;
- ACE zoletsa;
- analgesics;
- othandizira antifungal;
- Clofibrate;
- Clarithromycin;
- heparins;
- Sulfonamides;
- insulin;
- othandizira pakamwa ndi hypoglycemic.
Mankhwala otsatirawa amathandizira kuchepa kwa mphamvu ya Glyurenorm:
- Aminoglutethimide;
- sympathomimetics;
- mahomoni a chithokomiro;
- Glucagon;
- kulera kwamlomo;
- zinthu zomwe zimakhala ndi nikotini acid.
Glurenorm ndi amodzi mwa mankhwala omwe amadziwika kuti asinthe matenda a glycemia mwa anthu omwe ali ndi matenda a shuga a mtundu wachiwiri.
Kuphatikiza pa mankhwalawa, madokotala amatha kulimbikitsa kufananiza kwake:
- Glairie
- Konza;
- Glianov;
- Gliklada;
- Glibetic.
Tiyenera kukumbukira kuti kusintha kwa mlingo ndi kusintha kwa mankhwala kuyenera kuchitika kokha ndi dokotala.
Makanema okhudzana ndi matenda a shuga ndi njira zosungitsira shuga m'magazi:
Maganizo a odwala
Kuchokera pa ndemanga za odwala omwe akutenga Glurenorm, titha kunena kuti mankhwalawa amachepetsa shuga, koma adanenanso zoyipa zomwe zimakakamiza ambiri kuti asinthane ndi mankhwala a analog.
Ndakhala ndikuvutika ndi matenda ashuga a 2 kwa zaka zingapo. Miyezi ingapo yapitayo, dokotala wanga adandiyikira Glyurenorm, popeza Diabeteson sanali pamndandanda wa mankhwala aulere omwe amapezeka. Ndinatenga mwezi umodzi wokha, koma ndazindikira kuti ndibwerera ku mankhwala omwe ndidalandira kale. Glurenorm, ngakhale imathandizira kukhala ndi shuga wabwinobwino, koma imayambitsa mavuto ambiri (pakamwa lowuma, kudzimbidwa komanso kusowa kwa chilakolako chofuna kudya). Pambuyo pobwerera ku mankhwala am'mbuyomu, zizindikiro zosasangalatsa zidasowa.
Konstantin, wazaka 52
Nditapezeka ndi matenda a shuga, nthawi yomweyo adapereka mankhwala a Glyurenorm. Ndimakonda momwe mankhwalawo amathandizira. Shuga wanga amakhala ngati wabwinobwino, makamaka ngati simuphwanya zakudya. Sindidandaula za mankhwalawa.
Anna, wazaka 48
Ndili ndi matenda ashuga kwa zaka 1.5. Poyamba, kunalibe mankhwala; shuga anali wabwinobwino. Koma kenako adazindikira kuti pamimba yopanda chizindikiro zizindikiro zimachulukirachulukira. Dotolo adayala mapiritsi a Glurenorm. Nditayamba kumwa, nthawi yomweyo ndidamva. Shuga m'mawa adabweranso pazikhalidwe zabwino. Ndinkakonda mankhwalawo.
Vera, wazaka 61
Mtengo wa mapiritsi 60 a Glenrenorm ndi ma ruble pafupifupi 450.