MANINIL: MA ANALOGI A RUSSIAN NDI AKUNJA, MTENGO, CHINSINSI KU LATIN

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Maninil ndi mankhwala omwe ali ndi vuto la hypoglycemic, lomwe limapangidwira kukonzekera pakamwa ngati akudwala matenda osokoneza bongo omwe amadalira insulin (mtundu 2).

Ndiwe woyimira m'badwo wachiwiri wa sulfonylurea (PSM).

Monga mankhwala ena ambiri a hypoglycemic, Maninil ali ndi fanizo ku Russia ndi kunja - otsika mtengo komanso okwera mtengo, motero.

Feature

Kuchita ngati woyang'anira kagayidwe kazakudwala, Manin, atamwetsa, kumawonjezera chidwi cha insulin-receptors, kumalimbikitsa kutulutsa kwa insulin ndi insulin.

Kuphatikiza apo, imachepetsa gluconeogeneis wa hepatic ndi glycogenolysis, imalepheretsa kuchuluka kwa gluolose, komanso kuchepetsa magazi. Kutalika kwa hypoglycemic zotsatira zopangidwa ndi mankhwala 2 mawola pambuyo makonzedwe ali pafupifupi maola 12.

Mapiritsi Glibenclamide Maninyl 3.5 mg

Gawo lothandiza kuchepetsa shuga la Maninil - glibenclamide, yowonetsedwa mwa mawonekedwe owoneka ndi maso, limakhwimitsa thupi, chifukwa limalowa mwachangu m'mimba ndi 48-84%. Mutatha kumwa mankhwalawa, kutulutsidwa kwathunthu kwa glibenclamide kumachitika mkati mwa mphindi 5. Yogwira pophika imaphwanyidwamo m'chiwindi ndikupukusidwa ndi impso ndi bile.

Mankhwala amapangidwa piritsi ndi osiyana ndende ya yogwira piritsi 1:

1.75 mg;
3.5 mg;
5 mg

Mapiritsiwo ndi amtali-cylindrical mawonekedwe, ndi chamfer ndi chizindikiro chomwe chimayikidwa pakumaso kwina, mtundu wake ndi wapinki.

Wopanga mankhwalawa ndi FC Berlin-Chemie, m'masitolo amagulitsidwe kokha ndi mankhwala. Mankhwalawa amadzaza m'mabotolo agalasi loyera, ma PC 120 aliyense. Iliyonse, mabotolo omwewo amadzaza pamakatoni. Chinsinsi cha Latin ku Maninil ndi ichi: Maninil.

Malinga ndi kafukufuku, kutsatira nthawi yokwanira pakumwa mankhwala mosiyanasiyana kumachepetsa mwayi wokhala ndi mtima ndi zovuta zina zomwe zimayambitsidwa ndi matenda osakhudzana ndi insulin, kuphatikizapo kupha anthu omwe amayambitsidwa ndi matendawa.

Zizindikiro zogwiritsidwa ntchito

Manilin akuwonetsedwa kuti apeza mtundu wa insulin yodziyimira payekha ya matenda a shuga a mellitus (amtundu wachiwiri). Itha kutumikiridwa ngati mlingo woyima pawokha kapena kuphatikiza ndi mankhwala ena a hypoglycemic. Chosiyana ndi makina olumikizana ndi ma glinides ndi zotumphukira za sulfonylurea.

Mawonekedwe a Mlingo ndi makonzedwe

Kulowetsedwa kwa Maninil kumalimbikitsidwa musanadye, kutsukidwa osafwidwa.

Mlingo watsiku ndi tsiku umatsimikiziridwa ndi endocrinologist payekhapayekha:

ngati sichidutsa mapiritsi 2 patsiku, ndiye kuti mankhwalawo ayenera kumwedwa kamodzi, makamaka m'mawa - asanadye chakudya cham'mawa;
mukamapereka mankhwala okwanira, kugwiritsa ntchito mankhwalawa kumapangidwira mu 2 Mlingo - m'mawa - musanadye chakudya chamadzulo komanso madzulo - musanadye chakudya chamadzulo.

Zomwe zimafunikira posankha chithandizo cha mankhwalawa ndi kuchuluka kwa zaka, kuuma kwa matendawa, komanso kuchuluka kwa shuga m'magazi pamimba yopanda kanthu ndikatha kudya pambuyo pa maola awiri.

Pankhani yotsika mtengo wa mankhwala omwe dokotala angagwiritse ntchito, angasankhe kuiwonjezera. Njira yowonjezerera mlingo mpaka mulingo woyenera imachitika pang'onopang'ono - kuyambira masiku awiri mpaka asanu ndi awiri, nthawi zonse moyang'aniridwa ndi dokotala.

Pankhani yosinthira ku Maninil kuchokera kukonzekera kwina kwa mankhwala ndi hypoglycemic effect, kayendetsedwe kake kamayikidwa muyezo woyambirira, ngati kuli koyenera, kumawonjezeka, kumachitika mosamala komanso moyang'aniridwa ndi achipatala.

Mlingo Woyamba wa Maninil:

yokhala ndi 1.75 mg yogwira pophika - ndi mapiritsi 1-2 kamodzi patsiku. Pazipita mlingo salinso mapiritsi 6 patsiku;
yokhala ndi 3.5 mg yogwira ntchito - Piritsi limodzi / 2-1 kamodzi patsiku. Mlingo waukulu ndi mapiritsi atatu patsiku;
yokhala ndi 5 mg yogwira pophika - ndi piritsi 1 time nthawi imodzi patsiku. Mlingo woyenera wololera tsiku lonse ndi mapiritsi atatu.

Okalamba (wazaka zopitilira 70), omwe amatsatira malamulo oletsa kudya, komanso omwe ali ndi vuto lochepa kwambiri laimpso kapena chiwindi, tikulimbikitsidwa kugwiritsa ntchito kuchuluka kwa mankhwalawa chifukwa choopseza hypoglycemia.

Mukaphonya mlingo umodzi, mankhwalawa Maninil amapangidwa muyezo (wopanda kuchuluka) pa nthawi yanthawi zonse.

Zotsatira zoyipa

Maonekedwe akusokoneza ma kayendedwe ka makina ena pomwe akutenga Maninil samawonedwa kawirikawiri. Mawonetsero awo apang'ono amatha.

kuchokera m'mimba - mu mawonekedwe a mseru, malamba, kumva kupsinjika m'mimba, mawonekedwe a mawonekedwe achitsulo mkamwa, m'mimba;
kuchokera ku chiwindi - mu mawonekedwe a chiwindi michere, kukula kwa intrahepatic cholestasis kapena hepatitis;
kuchokera kumbali ya kagayidwe - mu mawonekedwe a kuwonda kapena hypoglycemia yokhala ndi zizindikiro zake - kunjenjemera, kutuluka thukuta, kusokonezeka kwa tulo, nkhawa, migraine, masomphenya kapena kuyankhula;
pa chitetezo chokwanira - mu mawonekedwe osiyanasiyana a thupi lawo siligwirizana pakhungu - petechiae, kuyabwa, hyperthermia, photosensitivity ndi ena;
kuchokera ku hematopoietic dongosolo - mu mawonekedwe a thrombocytopenia, hemolytic anemia, erythrocytopenia;
pa mbali ya ziwalo zowoneka - mwanjira yophwanya malo okhala.

Mfundo yofunika mukamamwa Maninil ndikusunga kwambiri malangizo a kuchipatala okhudzana ndi kadyedwe komanso plasma glucose wokha. Pankhani ya bongo, hypoglycemia yokhala ndi zizindikiritso ndizotheka.

Pakuwonetsedwa pang'ono kwa mankhwala osokoneza bongo, tikulimbikitsidwa kudya shuga pang'ono kapena zakudya zokhala ndi zophatikizika mosavuta zamagetsi. Pazokhudza mitundu yoopsa ya bongo, iv jekeseni wa shuga yakhazikitsidwa. M'malo mwa shuga, IM kapena subcutaneous jakisoni wa glucagon ndizovomerezeka.

Chiwopsezo cha hypoglycemia chimawonjezeka ngati:

kumwa mowa;
kusowa kwa chakudya chamagulu;
yopuma yayitali pakati pa chakudya;
kusanza kapena kudzimbidwa;
kulimbitsa thupi kwambiri.

Zizindikiro za hypoglycemia zitha kuphimbidwa ndikumamwa Maninyl ndi mankhwala omwe amakhudza dongosolo lamanjenje kapena amachepetsa kuthamanga kwa magazi.

Zotsatira za Maninil zitha kuchepetsedwa pomwe zimagwiritsidwa ntchito ndi barbiturates, njira zolerera komanso mankhwala ena okhala ndi mahomoni. Komanso, kugwiritsa ntchito nthawi imodzimodziyi kwa ma anticoagulants, reserpine, tetracyclines, anabolic steroids amatha kupititsa patsogolo ntchito zake.

Zolepheretsa ndi zotsutsana

Pochita ndi Maninil, tikulimbikitsidwa kupewa kutalikirana ndi dzuwa nthawi yayitali, komanso kusamala poyendetsa galimoto, kuchita zina zomwe zimafunikira chidwi, chidwi, komanso kugwira ntchito mwachangu.

Mankhwala a hypoglycemic amapatsirana chifukwa cha kukhalapo:

shuga wodalira insulin;
kulephera kwa chiwindi;
matumbo kutsekeka;
matenda ashuga ketoacidosis;
odwala matenda ashuga kapena precoma;
paresis am'mimba;
leukopenia;
lactose tsankho ndi kusowa kwa lactase;
kuchuluka kwa ntchito yogwira - glibenclamide kapena zigawo zina zomwe zimaphatikizidwa ndi mankhwala;
hypersensitivity ku PSM, komanso sulfonamides ndi okodzetsa okhala ndi zotumphukira za gulu la sulfonamide;
kuchotsedwa kwa kapamba.

Kulekedwa kwa Maninil ndi kulowetsedwa ndi insulin kupangidwa ngati:

matenda opatsirana omwe amakhala ndi ziwonetsero zoopsa;
zolowerera zowononga;
kuwotcha kwakukulu;
kuvulala
pakati kapena kufunika yoyamwitsa.

Mosamala, mankhwalawa amayenera kumwedwa pamaso pa kukanika kwa chithokomiro, adrenal cortex, kuledzera kwamphamvu chifukwa cha mowa.

Mankhwala a hypoglycemic amaphatikizidwa mwa ana.

Momwe mungasinthire Maninil: ma analogi ndi mtengo

Monga mankhwala ambiri, Maninil ali ndi mawu ofanana. Mofananamo muli mankhwala ambiri ochepetsa shuga, omwe amagwira ntchito omwe ali ndi glibenclamide.

Maninyl 3,5 analogu ali ndi izi:

Glibomet - kuchokera ku ruble 339;
Glibenclamide - kuchokera ma ruble 46;
Maninil 5 - kuchokera ku ruble 125.

Mapiritsi Glybomet

Odwala okhudzana ndi analogues ali ndi mafunso angapo, mwachitsanzo, ndibwino - Maninil kapena Glibenclamide? Pankhaniyi, zonse ndizosavuta. Glibenclamide ndi Maninil. Chachiwiri chokha ndi mtundu waukadaulo wapamwamba kwambiri woyamba.

Ndipo chiti ndibwino - Maninil kapena Glidiab? Pankhaniyi, palibe yankho lenileni, chifukwa zambiri zimatengera umunthu wa wodwalayo.

Mndandanda wa Maninil wa mtundu wachiwiri wa shuga ndi mankhwala:

Amaril - kuchokera ku ma ruble a 350;
Vazoton - kuchokera ma ruble 246;
Arfazetin - kuchokera ma ruble 55;
Glucophage - kuchokera ku ma ruble 127;
Mndandanda - kuchokera ku ruble 860;
Diabeteson - kuchokera ma ruble 278;
Xenical - kuchokera 800 ma ruble;
ndi ena.

Posankha analogue ya Maninil, akatswiri amalimbikitsa kupatsa chidwi ndi mankhwala omwe amapangidwa ndi makampani opanga mankhwala aku Japan, America ndi Western Europe: Gideon Richter, Krka, Zentiv, Hexal ndi ena.

Migwirizano ndi magwiritsidwe akusungidwa

Mankhwala a hypoglycemic Maninil amatha kukhalabe ndi machiritso kwa zaka zitatu, pokhapokha ngati amawasunga kutentha, m'malo otetezedwa ku kuwala ndi ana.