Kugwiritsa ntchito kwa Telsartan, komanso mankhwala ena omwe amatsutsana ndi maphikidwe a angiotensin a 2, akuwonetsedwa pazinthu zingapo zamatenda zomwe zimatsagana ndi kuwonjezeka kwa kuthamanga kwa magazi. Chida ichi chimakhala ndi nthawi yayitali. Zotsatira zake pambuyo pake zimagwiritsa ntchito kwa maola 48. Chida ichi chikuyenera kugwiritsidwa ntchito pokhapokha ngati dokotala akufotokozera komanso muyezo osapitilira zomwe zafotokozedwazi.
Dzinalo Losayenerana
Mankhwala a INN - Telmisartan.
ATX
M'magulu apadziko lonse a ATX, mankhwalawo ali ndi code C09CA07.
Kugwiritsa ntchito telsartan kumawonetsedwa pazikhalidwe zingapo zamatenda, limodzi ndi kuwonjezeka kwa kuthamanga kwa magazi.
Kutulutsa mafomu ndi kapangidwe kake
Chofunikira chachikulu cha mankhwalawa ndi telmisartan. Zomwe zimathandizira ku Telsartan zimaphatikizapo polysorbate, magnesium stearate, meglumine, sodium hydroxide, mannitol, povidone. Pali mitundu yosiyanasiyana ya mankhwalawa. Mankhwala Telsartan N, kuwonjezera telmisartan, akuphatikiza hydrochlorothiazide.
Mankhwala amapezeka piritsi. Kutengera ndi muyezo, 40 kapena 80 mg yogwira ntchito ingagwiritsidwe ntchito piritsi limodzi. Mapiritsi ali ndi mawonekedwe obisika okhala ndi chiopsezo chogawaniza komanso kuchuluka. Ndi zoyera. Chotumphukacho chimatha kukhala ndi mapiritsi 7 kapena 10. Pa mtolo wa makatoni, matuza 2, 3 kapena 4 atha kukhalapo. Kapangidwe ka mankhwala Telsartan AM, kuwonjezera pa telsimartan, palinso amlodipine.
Zotsatira za pharmacological
Kuchita kwa Telsartan, komwe ndi antigotin a mtundu wa 2 angiotensin, kutengera kuti chinthu ichi chojambula chimafanana kwambiri ndi mtundu uwu wa receptor. Chidacho chikugwirira ntchito mosankha. Ikhoza kuthana ndi angiotensin kuchokera kumangiriza ku AT1 receptors.
Mankhwala amapezeka piritsi.
Poterepa, mankhwala omwe agwiritsidwa ntchito mankhwalawa alibe kufanana ndi ma subtypes ena a AT receptors. Chifukwa chake, mutatenga 80 mg ya mankhwalawa, kuchuluka kwa magazi a yogwira ndikokwanira kutsekeka koopsa kwa mtundu 2 angiotensin.
Pankhaniyi, mankhwalawa samaletsa retin ndipo sasokoneza magwiridwe antchito a ion. Kuphatikiza apo, chida ichi chimachepetsa kuchuluka kwa aldosterone. Zomwe zimagwiritsidwa ntchito ndi mankhwalawa siziletsa ACE, chifukwa chake, pogwiritsa ntchito Telsartan, palibe zoyipa zomwe zimachitika chifukwa cha ntchito ya bradykinin. Zomwe zimagwiritsidwa ntchito ndi mankhwalawa sizikukhudza kugunda kwa mtima. Kugwiritsa ntchito mankhwalawa kumachepetsa chiopsezo cha kufa kwa odwala.
Pharmacokinetics
Mukamamwa mankhwalawo, chinthu chake chogwira ntchito chimayamba kugwira. Bioavailability ukufika 50%. Pazipita kuchuluka kwa mankhwala m'magazi amuna ndi akazi zimatheka pambuyo 3 mawola. Mankhwalawa amamangidwa ndi mapuloteni a plasma. Kagayidwe ka mankhwala kumachitika ndi kutenga nawo glucuronic acid. Ma metabolabol amamuchotsa ndowe mkati mwa maola 20.
Zizindikiro zogwiritsidwa ntchito
Kugwiritsidwa ntchito kwa Telsartan imafotokozedwa ngati chisonyezo chothandizira matenda osiyanasiyana a mtima, limodzi ndi kuwonjezeka kwa kuthamanga kwa magazi. Mankhwalawa amatha kugwiritsidwa ntchito pochiza anthu omwe ali ndi zizindikiro za thrombosis. Imathandizika pochiza odwala omwe ali ndi ischemic myocardial kuwonongeka.
Kugwiritsidwa ntchito kwa Telsartan imafotokozedwa ngati chisonyezo chothandizira matenda osiyanasiyana a mtima, limodzi ndi kuwonjezeka kwa kuthamanga kwa magazi.
Chidachi chimathandizira kuthana ndi matenda oopsa omwe abwera chifukwa chakumenyedwa. Mwa zina, wothandizira nthawi zambiri amapatsidwa mankhwala ochizira matenda oopsa kwa odwala omwe ali ndi vuto la mitsempha ya mitsempha. Ngati ndi kotheka, mankhwalawa angagwiritsidwe ntchito pochiza odwala omwe ali ndi matenda a shuga a 2.
Contraindication
Mankhwalawa sayenera kugwiritsidwa ntchito pamaso pa hypersensitivity kwa zigawo za Telsartan. Kuphatikiza apo, simungagwiritse ntchito mankhwalawa kuchiza odwala omwe ali ndi matenda amtundu wa 1 omwe amapweteka jakisoni nthawi zonse. Kuphatikiza apo, kugwiritsa ntchito mankhwala othandizira odwala omwe ali ndi matenda ashuga nephropathy akutenga ACE inhibitors sikulimbikitsidwa.
Simungagwiritse ntchito mankhwalawa kuchiza odwala omwe ali ndi matenda amtundu woyamba 1 omwe amaba jakisoni nthawi zonse.
Ndi chisamaliro
Chithandizo cha telsartan chimafuna kusamala kwambiri mu aimpso. Kuphatikiza apo, odwala omwe ali ndi mitral ndi aortic valve stenosis panthawi ya mankhwala a Telsartan amafunikira chisamaliro chapadera kuchokera kwa akatswiri azachipatala. Kusamalidwa kwapadera kuyenera kumwedwa ndi hypokalemia ndi hyponatremia. Ndizotheka kugwiritsa ntchito mankhwalawa pokhapokha moyang'aniridwa ndi madokotala ndipo ngati wodwala ali ndi mbiri yokhudza kupatsirana kwa impso.
Kodi kutenga telsartan?
Chogwiritsidwacho chikuyenera kutengedwa nthawi imodzi patsiku, bwino kwambiri m'mawa. Kudya sizikhudzana ndi mayamwa a yogwira mankhwala. Kuti athetse kuthamanga kwa magazi, mlingo woyambirira wa 20 mg umapangidwa tsiku lililonse. M'tsogolomu, mlingo umatha kuwonjezeka mpaka 40 kapena 80 mg.
Ndi matenda ashuga
Kwa odwala omwe ali ndi matenda a shuga a mtundu wachiwiri, mankhwalawa adapangidwa muyezo wa 20 mg. M'tsogolomu, mlingo wa tsiku ndi tsiku ukhoza kuwonjezeka mpaka 40 mg.
Kudya sizikhudzana ndi mayamwa a yogwira mankhwala.
Zotsatira zoyipa za Telsartan
Kugwiritsa ntchito telsartan kumalumikizidwa ndi chiopsezo cha zovuta zingapo. Odwala nthawi zambiri amakhala ndi vertigo, kufooka, kupweteka pachifuwa, komanso matenda ofanana ndi chimfine.
Matumbo
Kugwiritsidwa ntchito kwa Telsartan nthawi zambiri kumabweretsa kuwoneka kwa ululu wam'mimba komanso vuto la dyspeptic.
Kuchokera kumbali ya kagayidwe ndi zakudya
Odwala omwe ali ndi matenda a shuga, kugwiritsa ntchito telsartan kumatha kupangitsa hypoglycemia ndi hyperkalemia.
Pakati mantha dongosolo
Chipangizocho chimatha kuyambitsa kugona. Kutha kukomoka.
Kuchokera kumbali ya dongosolo lamkati lamanjenje, zoyipa zamkati mwa mawonekedwe akukomoka ndizotheka.
Kuchokera kwamikodzo
Kutenga Telsartan kungayambitse kupweteka kwambiri kwaimpso.
Kuchokera ku kupuma
Mankhwala a Telsartan amatha kuyambitsa kutsokomola komanso kupuma movutikira. Matenda am'mapapo amatha. Chifukwa cha kuchepa kwa chitetezo chokwanira pakumwa mankhwalawa, matenda opatsirana m'mapapo amatha kuyamba.
Pa khungu
Pa mankhwala ndi Telsartan, kukula kwa hyperhidrosis nthawi zambiri kumawonedwa mwa odwala.
Kuchokera ku genitourinary system
Odwala ena amakhala ndi cystitis. Nthawi zina, chifukwa cha matenda oopsa a genitourinary system, sepsis imatha kuchitika.
Odwala ena amakhala ndi cystitis.
Kuchokera pamtima
Ndi mankhwala a Telsartan, kugunda kwa mtima kumatha kuchuluka. Pali mwayi wokhala ndi bradycardia ndikuchepetsa kuthamanga kwa magazi. Kuphatikiza apo, kuchepa kwa magazi m'thupi kumatha.
Kuchokera musculoskeletal system ndi minofu yolumikizana
Pochiza ndi Telsartan, ululu wammbuyo komanso kukokana kwa minofu kumatha kuchitika. Kuphatikiza apo, kuchitika kwa myalgia ndi arthralgia kumatha kuchitika.
Pa mbali ya chiwindi ndi biliary thirakiti
Ndizachilendo kwambiri pochiza Telsartan kuti pali kuphwanya chiwindi ndi ma biliary.
Ndi kawirikawiri kwambiri pochiza Telsartan kuti pali kuphwanya chiwindi.
Matupi omaliza
Ngati wodwala ali ndi hypersensitivity, thupi lawo siligwirizana, limatchulidwa ngati zotupa pakhungu komanso kuyabwa, komanso edema ya Quincke.
Zokhudza mphamvu pakuwongolera njira
Popeza mphamvu ya mankhwalawa imayambitsa kugona komanso chizungulire, chisamaliro chiyenera kutengedwa mukamayendetsa.
Malangizo apadera
Mankhwalawa sayenera kumwa ndi amayi omwe akukonzekera kutenga pakati posachedwa. Gawo lolimbikira la chinthu limayipitsa chonde. Kuphatikiza apo, kusamala kuyenera kugwiritsidwa ntchito mwa anthu omwe ali ndi chitetezo chokwanira.
Gwiritsani ntchito panthawi yoyembekezera komanso mkaka wa m`mawere
Chithandizo cha Telsartan cha amayi mu trimesters onse am'mimba sichiri chovomerezeka. Sikulimbikitsidwa kugwiritsa ntchito mankhwalawa poyamwitsa.
Chithandizo cha Telsartan cha amayi mu trimesters onse am'mimba sichiri chovomerezeka.
Kupangira Telsartan kwa Ana
Popeza kuti chitetezo cha Telsartan cha ana ndi achinyamata sichinaphunzire, sikulimbikitsidwa kugwiritsa ntchito mankhwalawa pochiza odwala otere.
Gwiritsani ntchito mu ukalamba
Mankhwalawa amatha kugwiritsidwa ntchito pochiza okalamba. Pankhaniyi, kusintha kwa mlingo sikofunikira.
The ntchito aimpso kuwonongeka
Kugwiritsa ntchito telsartan ndikuloledwa kwa odwala omwe ali ndi vuto laimpso. Pali umboni wa kugwiritsa ntchito bwino kwa mankhwalawa pochiza anthu omwe amakhala akutsutsana ndi hemodialysis. Izi zimafunikira kusanthula kwathunthu kwamwazi wa potaziyamu m'magazi.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Mankhwalawa sangathe kugwiritsidwa ntchito pochiza anthu omwe ali ndi matenda a chiwindi, limodzi ndi kutsekeka kwa machitidwe a biliary ndi cholestasis.
Mankhwalawa sangathe kugwiritsidwa ntchito pochiza anthu omwe ali ndi matenda a chiwindi, limodzi ndi kutsekeka kwa machitidwe a biliary ndi cholestasis.
Mankhwala osokoneza bongo a Telsartan
Pa mlingo umodzi waukulu kwambiri wa mankhwalawa, bradycardia ndi tachycardia amatha kuoneka. Nthawi zina, magazi amachepa. Pankhani ya bongo, chithandizo cha mankhwala amayatsidwa.
Kuchita ndi mankhwala ena
Mukamamwa Telsartan nthawi yomweyo ndi mankhwala a immunosuppression, COX-2 inhibitors, heparin, komanso okodzetsa, chiopsezo chokhala ndi hyperkalemia chikuwonjezeka. Kugwiritsa ntchito molumikizana ndi mankhwala osapweteka a antiidal omwe amachepetsa mphamvu ya antihypertensive ya Telsartan.
Kuphatikiza apo, kuphatikiza kwa antihypertensive mankhwala okhala ndi maimolowedwe oboola thupi, kuphatikiza Furasemide ndi hydrochlorothiazide, zimawonjezera chiopsezo chodzetsa chisokonezo pamlingo wamagetsi wamagetsi komanso kuchepa kwakukulu kwa kuthamanga kwa magazi. Kugwiritsa ntchito telsartan kuphatikiza ndi lithiamu kumawonjezera poizoni wa womaliza. Ndi kugwiritsa ntchito pamodzi kwa Telsartan ndi systemic corticosteroids, kuchepa kwa mphamvu ya antihypertensive kumawonedwa.
Kuyenderana ndi mowa
Muyenera kukana kumwa mowa panthawi ya Telsartan.
Muyenera kukana kumwa mowa panthawi ya Telsartan.
Analogi
Masinthidwe a Telsartan omwe ali ndi zofanana ndi achire zotsatira amaphatikizapo:
- Mikardis.
- Izi.
- Telmitarsan.
- Wotsogolera.
- Irbesartan.
- Nortian.
- Makandulo.
- Kosaaar.
- Muziyamwa.
- Telpres.
Kupita kwina mankhwala
Mankhwala angagulidwe ku pharmacy ndi mankhwala.
Mtengo wa telsartan
Mtengo wa Telsartan m'masitolo azachipatala kuchokera pa 220 mpaka 260 rubles.
Zosungidwa zamankhwala
Sungani mankhwalawo kutentha.
Sungani mankhwalawo kutentha.
Tsiku lotha ntchito
Mutha kugwiritsa ntchito mankhwalawa kwa zaka ziwiri kuyambira tsiku lopangidwa.
Wopanga
Telsartan imapangidwa ndi Dr. Reddy's Laboratories Ltd., India.
Umboni wochokera kwa madokotala ndi odwala za Telsartan
Margarita, wazaka 42, Krasnodar
Pogwira ntchito monga mtima wamtima, nthawi zambiri ndimakumana ndi odwala omwe ali ndi madandaulo a kuthamanga kwa magazi. Makamaka nthawi zambiri, vuto limodzimodzilo limapezeka mwa anthu opitilira zaka 40, kuwonjezeka kwa kuthamanga kwa magazi kumabweretsa kuwonongeka kolemekezeka komanso kumapangitsa zofunikira kuti ziwoneke bwino, kuphatikizapo kugunda kwa mtima. Zikatero, ndimakonda kulemba Telsartan kwa odwala. Mankhwalawa amaloledwa ndi thupi ndipo nthawi zambiri amakhumudwitsani mawonekedwe. Pankhaniyi, mankhwalawa ali ndi tanthauzo lodziwika bwino.
Igor, wazaka 38, Orenburg
Nthawi zambiri ndimapereka Telsartan kwa odwala omwe ali ndi madandaulo a kuthamanga kwa magazi. Mankhwala ali ndi wofatsa antihypertensive. Pankhaniyi, mankhwalawa atha kuphatikizidwa ndi zovuta mankhwala. Mankhwala angagwiritsidwe ntchito kupewa matenda a mtima. Mankhwalawa sakulitsa mkhalidwe wa odwala omwe ali ndi atherosulinosis ya ziwiya zotumphukira.
Vladimir, wazaka 43, Rostov-on-Don
Kugwiritsa ntchito Telsartan nthawi zambiri kumalimbikitsidwa kwa odwala omwe ali ndi kuthamanga kwa magazi omwe ali ndi mbiri ya matenda a shuga a 2. Kugwiritsidwa ntchito kwa Telsartan mwa odwala kotereku sikupangitsa kuti ziwonongeke kwambiri komanso nthawi yomweyo zimachepetsa kuthamanga kwa magazi. Mankhwala mu odwala amachepetsa chiopsezo cha matenda a mtima.
Marina, wazaka 47, Moscow
Vuto la kudumphadumpha kwa magazi komwe ndidakhala nako zaka 10 zapitazo. Munthawi imeneyi ndinayesa mankhwala ambiri. Pafupifupi zaka ziwiri zapitazo, monga adokotala adalembera, adayamba kumwa Telsartan. Mankhwalawo anali chipulumutso changa. Piritsi limodzi patsiku ndilokwanira kusunga kukakamiza konse tsiku lonse. Komanso, ngakhale nditha kuiwala kumwa mankhwalawo, sindinawonepo kuwonjezeka kowopsa kwa kuthamanga kwa magazi tsiku lonse. Ndine wokhutira ndi momwe ogwiritsira ntchito Telsartan. Sindinawonepo zodetsa zilizonse.
Dmitry, wazaka 45, St. Petersburg
Kulandiridwa kwa Telsartan kunayamba potsatira kuvomerezedwa ndi mtima. Kwa ine, mankhwalawa ndi oyenera. Ngati, ndikugwiritsa ntchito mankhwala ena, magazi anga atadumpha kwambiri, zomwe zidakhudza thanzi langa, ndiye nditatha kutenga Telsartan ndidaiwala za vuto la kuthamanga kwa magazi. Sindinawone zotsatira zoyipa kuchokera pakugwiritsa ntchito mankhwalawa kwa nthawi yoposa chaka chimodzi chogwiritsa ntchito mankhwalawa.
Tatyana, wazaka 51, Murmansk
Kuthamanga kwa magazi kwakhala kukundivutitsa kwazaka zopitilira 15. Ndinagwiritsa ntchito mankhwala osiyanasiyana komanso kuphatikiza kwawo monga momwe madokotala amafotokozera, koma zotsatira zake zinali zakanthawi. Pafupifupi zaka 1.5 zapitazo, dokotala wa mtima adalemba Telsartan. Ndikumwa mankhwalawa tsiku lililonse mpaka pano. Zotsatira zake zimakhala zokwanira. Kupanikizika kwakhazikika, palibe ma surges. Palibe mavuto omwe adawonedwa.
