Espa-Lipon 600 ndi mankhwala omwe amapezeka mwanjira ya mapiritsi kapena jakisoni. Limagwirira ntchito ndi katundu zimadalira mphamvu ya alpha-lipoic acid, amene ali gawo la mankhwala. Mankhwalawa amagwiritsidwa ntchito ngati gawo limodzi la mankhwala ochizira matenda a shuga kapena mowa mwauchidakwa. Thioctic acid sinafotokozedwenso kwa ana kapena amayi apakati, chifukwa palibe umboni wazomwe zimapangitsa kuti thupi lizikula.
Dzinalo Losayenerana
Thioctic acid.
Dzina losakhala la dziko lonse Espa-Lipon ndi Thioctic acid.
ATX
A05BA.
Kutulutsa mafomu ndi kapangidwe kake
Wogwiritsa ntchito wa metabolic amapangidwa mu mawonekedwe a yankho la jakisoni ndi mawonekedwe a piritsi. M'mawu omaliza, zigawo za kukonzekera zimakutidwa ndi filimu yopyapyala yopangidwa ndi hypromellose, macrogol 6000, titanium dioxide ndi talc. Pakatikati pa piritsi pali 600 mg ya yogwira - alpha-lipoic kapena thioctic acid. Pofuna kukonza mayamwidwe a chinthucho ndikuthandizira kuwonongeka kwamatumbo, mawonekedwe a piritsi amathandizidwa ndi zinthu zothandizira, monga:
- microcrystalline cellulose ufa;
- povidone;
- shuga mkaka;
- silicon dioxide colloidal wopanda madzi;
- sodium carboxymethyl wowuma;
- magnesium wakuba.
Mapiritsi olimbitsa ali ndi mawonekedwe a biconvex. Utoto wamtunduwu ndi wachikaso zachikaso chifukwa cha utoto wa quinoline wa mthunzi womwe umagwirizana.
Espa-Lipon yankho la jakisoni ali m'magalasi ophatikizira galasi, omwe ali ndi 600 mg ya ethylene bis salt ya alpha lipoic acid.
Njira yothetsera jakisoni ili mgulu la magalasi, omwe ali ndi 600 mg ya ethylene bis salt ya alpha lipoic acid. Madzi osalala amagwiritsidwa ntchito ngati chosungunulira.
Zotsatira za pharmacological
Alpha lipoic acid imasintha kagayidwe. Gawo lolimbikira limalimbikitsa kagayidwe kazakudya mthupi chifukwa cha kukoka kwa okosijeni a asidi a pyruvic acid ndi alpha-keto acid. Mwa magawo a biochemical, thioctic acid ndi ofanana ndi mavitamini a B.
The yogwira mankhwala ndi amkati antioxidants. Zimatenga gawo mu mafuta ndi chakudya cha metabolism. Alpha-lipoic acid ali ndi lipid-kuchepetsa, amachepetsa cholesterol ya plasma, amasintha ntchito ya chiwindi komanso amalimbikitsa kuthana ndi poizoni m'thupi. Mankhwala amakhala ngati maselo amitsempha yama trophic.
Pharmacokinetics
Mukamwa pakamwa, alpha lipoic acid imatengedwa mwachangu m'matumbo. Kugwiritsa limodzi mapiritsi ndi chakudya kumachepetsa kuyamwa kwa thioctic acid. Bioavailability ndi 30-60%. Kuyamwa kochepa kwa chinthu yogwira ntchito kumachitika chifukwa cha gawo loyambirira la mankhwalawa kudzera mu hepatocytes, pomwe mankhwala amapanga masinthidwe.
Gawo lomwe limagwira limafikira kuchuluka kwambiri kwa seramu m'magazi pambuyo pa mphindi 25-60. Kutha kwa theka la moyo kumapangitsa mphindi 20-50. Alpha-lipoic acid imachoka m'thupi kudzera mu kwamikodzo ndi 80-90%.
Gawo lolimbikira la Espa-Lipon limafikira kwambiri m'magazi pambuyo pa mphindi 25-60.
Zizindikiro zogwiritsidwa ntchito
Mankhwalawa amagwiritsidwa ntchito popita kuchipatala kuti amuchotsetse mowa ndi matenda a shuga. Jakisoni wamkati amatha kugwiritsidwa ntchito pochiza matenda amchiwindi: matenda a chiwindi, kutupa (hepatitis), kuledzera kapena mankhwala osokoneza bongo a hepatocytes. Alpha-lipoic acid imatha kuchepetsa mkhalidwe wa wodwalayo ndikuthandizira kuchotsa zinthu zapoizoni poizoni ndi mchere wamphamvu, bowa kapena mankhwala.
Nthawi zina, Espa-Lipon amagwiritsidwa ntchito ngati mankhwala ochepetsa lipid motsutsana ndi maziko a mtima wamatenda komanso kutsitsa cholesterol. Zotsirizazo ndizomwe zimapangira mapangidwe a atherosselotic plaques pamitsempha ya mtima ya mitsempha yayikulu komanso yotumphuka.
Contraindication
Mankhwala ndi contraindicated pamaso pa hypersensitivity kwa kapangidwe zinthu za Espa-Lipon, ndi lactose tsankho.
Ndi chisamaliro
Mankhwala ayenera kuikidwa mosamala vuto la chiwindi ndi impso.
Espa-Lipon 600 ayenera kutumikiridwa mosamala ngati vuto la chiwindi likulephera.
Momwe mungatenge Espa-Lipon 600
Kukonzekera kwamlomo wamankhwala kumachitika kamodzi patsiku, kumwa piritsi limodzi (600 mg) pamimba yopanda kanthu. Sitikulimbikitsidwa kugwiritsa ntchito piritsi yowonongeka, chifukwa kuphwanya kwamakina kwa enteric kolimba kumachepetsa kuyamwa ndi kuchiritsa kwa alpha lipoic acid. Mapiritsi amagwiritsidwa ntchito ngati njira yolepheretsa kapena pambuyo pa kutha kwa makulitsidwe a makolo, njira yomwe idatenga milungu 2-4.
Mankhwala okhala ndi mapiritsi salinso miyezi itatu. Mwapadera, kuwonjezeka kwa nthawi yonse ya chithandizo ndikotheka. Kutalika kwa mankhwalawa kumatsimikiziridwa ndi katswiri wazachipatala malinga ndi kuchuluka kwa minofu komanso kusintha kwa chithunzi cha matenda.
Intravenous makonzedwe ikuchitika mu mawonekedwe a infusions. Wotsitsa amayikidwa 1 nthawi patsiku wopanda kanthu. The concentrate kapena yankho limatsitsidwa mu 0,9% saline sodium chloride solution. Mu polyneuropathy yovuta, 24 ml ya Espa-Lipon imadzipaka 250 ml ya sodium chloride 0,9%. Wotsitsa amaikidwa kwa mphindi 50.
Kumwa mankhwala a shuga
Odwala omwe ali ndi matenda ashuga amafunika kuwongolera shuga m'magazi pogwiritsa ntchito muyezo wa Espa-Lipon.
Zotsatira zoyipa
Kugwiritsa ntchito moyenera mankhwalawa malinga ndi malangizo ogwiritsira ntchito, ngozi ya mavuto amachepetsa. Nthawi zambiri, zotsatirazi zotsatirazi zidachitika:
- kutsika kwa plasma shuga ndende;
- thupi lawo siligwirizana kuwonekera pakhungu mawonekedwe a eczema kapena urticaria;
- thukuta;
- kukula kwa anaphylactic kugwedezeka komanso mawonekedwe a hematomas.
Ndi chiwopsezo chachikulu cha mankhwala, minyewa kukokana, diplopia, kupweteka kwa mutu, kulemera m'makachisi, kupuma kovuta kumachitika.
Nthawi zambiri, mavuto amayamba okha.
Zokhudza mphamvu pakuwongolera njira
Mankhwala alibe inhibitory pa zinchito zake chapakati ndi zotumphukira mantha dongosolo. Poona zomwe zingachitike mutakumana ndi zovuta (zopweteka, chizungulire), chisamaliro chikuyenera kuchitika mukamayendetsa zida zovuta ndi galimoto, chifukwa ntchito yotere imafuna kuyankhidwa mwachangu komanso mosamala.
Malangizo apadera
Ndikofunikira kudziwitsa wodwalayo za zomwe zingachitike paresthesia - zovuta zamaganizidwe. Njira yakanthawi yochepa yamatsenga ikukula motsutsana ndi maziko amakonzanso minyewa yamitsempha mankhwalawa polimbana ndi polyneuropathy ndi alpha lipoic acid. Wodwalayo amatha kumva kuti ndi "goosebumps."
Odwala omwe amayamba chifukwa cha anaphylactoid zimachitika amayenera kupatsidwa mayesero owopsa asanayambe kukonzekera. Mwa kuyambitsa 2 ml ya mankhwala pansi pa khungu, kulolera kwa mankhwalawo ku thupi kumatha kupezeka. Pankhani ya kuyabwa, nseru komanso kusapeza bwino, chithandizo chamankhwala chiyenera kuyimitsidwa nthawi yomweyo. Ngati angioedema ndi anaphylactic mantha amachitika, glucocorticosteroids ndi ofunika.
Ngakhale mukutenga Espa-Lipon 600, kuyamwitsa sikulimbikitsidwa.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Mankhwala amatchulidwa pa nthawi yoyembekezera pokhapokha ngati zotsatira zoyipa za alpha lipoic acid pamthupi la mayi zimaposa chiopsezo cha matenda obwera chifukwa cha mluza. Kuwerengera kotereku ndikofunikira chifukwa palibe chidziwitso chazachipatala pazokhudzana ndi thioctic acid kuti mulowetse chotchinga cha hematoplacental.
Munthawi ya mankhwala, mankhwalawa ali osavomerezeka.
Chithandizo cha Espa-Lipon cha Ana 600
Kafukufuku wachipatala wazokhudza mphamvu ya mankhwalawa pakukula ndi kukula kwa thupi muubwana ndi unyamata sizinachitike. Monga njira yachitetezo, kayendetsedwe kapena kayendetsedwe ka alpha lipoic acid sikulimbikitsidwa mpaka zaka 18.
Gwiritsani ntchito mu ukalamba
Mwa anthu azaka zopitilira 50, mapiritsi a pharmacokinetic a thioctic acid sanaoneke akamamwa mapiritsi, kotero okalamba safunika kusintha mwatsatanetsatane. Intravenous makonzedwe amachitika pokhapokha moyang'aniridwa ndi dokotala.
Bongo
Mukamwa 10-25 g ya mankhwalawa, kutulutsa magazi kutchulidwa kumachitika, kukomoka kwa hypoglycemic kumayamba, ndipo mulingo wa asidi m'mthupi umasokonekera. Kuledzera kwambiri kumayamba. Wovutitsidwayo amafunikira kuchipatala mwachangu.
Wovutitsidwayo amafunikira kuchipatala msanga ngati Espa-Lipon wambiri.
Kuchita ndi mankhwala ena
Mu maphunziro oyamba komanso otsatsa malonda ndikugwiritsa ntchito kwa Espa-Lipon ndi mankhwala ena, zochitika zotsatirazi zidawululidwa:
- Mankhwala amachepetsa mphamvu ya cisplatin.
- Ndikofunikira kuyang'anira kuchuluka kwa shuga wamagazi ndi kuphatikiza kwa alpha-lipoic acid ndi insulin kapena mankhwala ena a hypoglycemic. Espa-Lipon amatha kukulitsa chidwi cha zotumphukira zimakhala ndi mahomoni a beta cell a kapamba. Kutengera mphamvu zomwe mwapeza, ndikulimbikitsidwa kusintha kuchuluka kwa ndalama zofunika kukwaniritsa chiwongolero cha glycemic.
- Thioctic acid imatha kuyanjana ndi ma ionic zitsulo zovuta ndi mawonekedwe a maselidesides a saccharides, kuphatikizapo levulose, kuti apange ma tata. Chifukwa chake, kugwiritsidwa ntchito kofananako kwa mankhwalawo ndi zowonjezera zakudya, zakudya zamkaka (chifukwa cha kukhalapo kwa calcium ion) kapena othandizira okhala ndi mchere wa chitsulo ndi magnesium ndizoletsedwa. Pa mankhwala othandizira, tikulimbikitsidwa kuti muzisunga pakatikati pa kutenga Espa-Lipon ndi chakudya kwa maola 2-4.
- Kusagwirizana kwa mankhwala kumawonedwa ndikumapukusa thioctic acid mu mawonekedwe a yankho mu 5% dextrose, yankho la Ringer.
Mankhwala amatha kuwonjezera mphamvu ya anti-yotupa ya glucocorticosteroids.
Kuyenderana ndi mowa
Pa mankhwala, kugwiritsa ntchito zakumwa, mankhwala osokoneza bongo ndi zakudya zomwe zimakhala ndi ethyl mowa ndizoletsedwa. Ndi mowa womwewo komanso Espa-Lipon, kufooka kwa njira zochizira kumawonedwa.
Pa kumwa kwa Espa-Lipon 600, kugwiritsa ntchito zakumwa zoledzeretsa ndizoletsedwa.
Mowa wa Ethyl ndi mankhwala ake a metabolic angayambitse kubadwa kwa polyneuropathy mobwerezabwereza mutatenga Espa-Lipon ngati prophylactic.
Analogi
Mankhwala otsatirawa ndi amodzi ofanana ndi omwe ali ndi mawonekedwe ofanana ndi a Espa-Lipon:
- Oktolipen;
- Thioctacid BV;
- Berlition 600;
- Thiogamm;
- Thiolipone;
- Lipoic acid;
- Neuroleipone.
Kubwezera mankhwala sikumayendera limodzi ndi kuchepa kwapang'onopang'ono kwa sabata limodzi, chifukwa Espa-Lipon samayambitsa zizindikiro zosiya.
Miyezo ya tchuthi Espa Lipona 600 kuchokera ku pharmacy
Mankhwala amagulitsidwa ku pharmacies ndi mankhwala.
Kodi ndingagule popanda kulandira mankhwala?
Ndi mtundu wolakwika wa mankhwalawo, zotsatira zoyipa zimayamba, kotero kugulitsa kwaulere kwa mankhwalawa popanda zowonetsera zachipatala kumakhala kochepa.
Mtengo wa espa lipon 600
Mtengo wapakati wamankhwala mumalo ogulitsa otsimikizika amasiyana 656 mpaka 787 rubles.
Zosungidwa zamankhwala
Mapiritsi ndi yankho la jakisoni amaloledwa kusungidwa kutentha kwa + 15 ... + 25 ° C. Pofuna kusamalira mitundu ya Mlingo, zinthu zofunikira chinyezi komanso kusowa kwa dzuwa ndikofunikira.
Tsiku lotha ntchito
Zaka 2
Wopanga Espa Lipona 600
Siegfried Hamelin GmbH, Germany.
Mapiritsi a Espa-Lipon ndi yankho la jakisoni amaloledwa kuti asungidwe kutentha kwa + 15 ... + 25 ° C.
Ndemanga pa Espa Lipone 600
Kuchotsa kwathunthu kwa odwala matenda ashuga kapena mowa mwauchidakwa, Espa-Lipon monotherapy sikokwanira, chifukwa mabungwe ochezera pa intaneti odwala amawona achire.
Madokotala
Olga Iskorostinskova, endocrinologist, Rostov-on-Don
Ndikuganiza kuti Espa-Lipon ndi mankhwala apamwamba kwambiri okhala ndi thioctic acid. Ndimagwiritsa ntchito mankhwala othandizira kulowa mu mtsempha, kenako ndikusintha mapiritsi. Ndimawona lipotropic kwambiri muzochita zamankhwala. Mankhwala amathandiza kuchepetsa kuledzera kwa thupi. Chokhacho chomwe chimabweza ndi mtengo wokwanira pamagululi komanso mapiritsi. Mankhwala amapatsidwa odwala ngati antioxidant mankhwala a matenda a shuga a polyneuropathies.
Elena Mayatnikova, katswiri wa zamitsempha, St.
Espa-Lipon ndi njira yothandizira yokhazikika pazochitika za thioctic acid, mankhwala apakhomo. Ndimagwiritsa ntchito mankhwala ochizira polyneuropathy a matenda ashuga kapena uchidakwa, komanso kuwonongeka kwa zotumphukira zamitsempha motsutsana ndi maziko a tunnel syndromes. Anthu omwe ali ndi matenda ashuga amafunika kumwa alpha-lipoic acid ngati mapiritsi 2 kawiri pachaka, kuti muchepetse kuchitika kwa polyneuropathy. Mwa odwala ambiri, mankhwalawa amalekeredwa bwino, ndipo sanaonepo zoyipa zilizonse machitidwe ake.
Odwala
Malvina Terentyeva, wazaka 23, Vladivostok
Ndine wokhutira ndi zotsatira zake nditatha kulandira chithandizo ndi Espa-Lipon. Dotolo adayikira mapiritsi chifukwa cha kukhalapo kwa zizindikilo za kusintha kwa msana. Njira ya pathological idawonetsedwa mu mawonekedwe a osteochondrosis a digiri yoyamba. Thupi linalandira bwino mankhwalawo, thanzi labwinolo, ndipo mankhwalawo sanayambitse zotsatirapo zake. Mukapereka magazi kuti muwoneke, zidapezeka kuti cholesterol yatsika: inali 7.5 mmol, inadzakhala 6. Tsitsi lathanzi labwino lidawonekera.
Evgenia Knyazeva, wazaka 27, Tomsk
Ndimagwiritsa ntchito mankhwalawa pongofuna kupewa. Mankhwala a polyneuropathy, momwe mankhwalawa amathandizira pakhungu ndi kugwiritsa ntchito mapiritsi, sizinadziwike. Espa-Lipon sanakwanitse kukonza chithunzithunzi. Madokotala adakulitsa vutoli ndi mankhwala ena, pambuyo pake adayika Espa-Lipon ngati njira yothandizira. Ndikhulupirira kuti zabwino zili pamtengo wotsika mtengo.
