Mpaka pano, mapiritsi a Formetin adzipanga okha ngati njira yothandiza kwambiri polimbana ndi matenda osokoneza bongo a fomu yodziyimira payekha. Chifukwa chogwira ntchito komanso mtengo wotsika mtengo, mankhwalawa akufunika kwambiri pakati pa odwala matenda ashuga.
Metformin yogwira ntchito (mnn) ndi gawo lamankhwala ambiri ochepetsa shuga, kuphatikiza mapiritsi a Formetin. Ndi gawo lothandizika kuchokera ku gulu la Biguanides a m'badwo wachitatu ndipo limathandizira kuchepetsa milingo yamagazi.
Forometine imakonda kutumikiridwa kwa odwala omwe ali ndi matenda a shuga 2, makamaka ngati matendawa amapezeka ndi kunenepa kwam'mimba.
Wothandizira antidiabetesic amalepheretsa ntchito ya gluconeogenesis, kayendedwe ka ma elekitironi a ma kupuma ma mitochondria. Glycolysis imakhudzidwa, maselo amayamba kuyamwa bwino, ndipo mayamwidwe ake ndi makoma am'mimba amachepa.
Chimodzi mwazabwino za mankhwala a formmetin ndikuti siziwonjezera kutsika kwa shuga. Izi ndichifukwa choti metformin hydrochloride, ngati gawo logwira ntchito, sichinthu chosangalatsa popanga chinsinsi cha insulin.
Zabwino za piritsi kukonzekera
Zizindikiro zazikulu pakugwiritsa ntchito mankhwalawa ndi motere:
- kukhalapo kwa metabolic syndrome kapena mawonekedwe a insulin kukana;
- Monga lamulo, pamaso pa insulin kukana, kunenepa kwambiri kumakula mwa odwala, chifukwa cha zotsatira za metformin komanso kuyang'anira zakudya zapadera zamagulu, kuchepa thupi pang'onopang'ono kumatheka;
- ngati pali kuphwanya kwa kulolerana kwa shuga;
- Matenda a ovopolycystic ovary matenda;
- matenda a shuga a insulin-odziimira okha ngati monotherapy kapena gawo limodzi la chithandizo chokwanira;
- mawonekedwe a shuga omwe amadalira insulin molumikizana ndi jakisoni wa insulin.
Ngati tingayerekeze mankhwala Fomepeni ndi mankhwala ena ochepetsa shuga, zotsatirazi zazikuluzikulu za metformin ziyenera kufotokozeredwa:
- Zake pakuchepetsa kukana kwa insulin mwa wodwala. Metformin hydrochloride imatha kuwonjezera kukhudzika kwa maselo ndi minyewa ku glucose wopangidwa ndi kapamba.
- Kutenga mankhwalawo kumayendetsedwa ndi mayamwidwe ake ndi ziwalo zam'mimba. Chifukwa chake, kuchepetsa kuchepa kwa shuga ndi m'matumbo kumatheka.
- Amathandizira poletsa chiwopsezo cha chiwindi, chomwe chimatchedwa kuperekera shuga.
- Zimathandizira kuchepetsa kulakalaka, komwe ndikofunikira kwambiri kwa odwala matenda ashuga onenepa kwambiri.
- Zimakhala ndi phindu pa cholesterol, kuchepetsa zoyipa ndikuwonjeza zabwino.
Kuphatikiza apo, mankhwalawa amathandizira kuti magawo azikhala ochepa.
Malangizo ogwiritsira ntchito mapiritsi
Formetin imakhala ndi malangizo ogwiritsa ntchito ponena kuti mankhwalawa amapezeka piritsi la mawonekedwe a biconvex oyera mapiritsi.
Kuphatikizika kwa mankhwalawa kumaphatikizapo ntchito yogwira ntchito ya Metformin hydrochloride ndi zigawo zina zothandizira mu mawonekedwe a magnesium stearate, povidone ndi croscarmellose sodium.
Mlingo wotsatira wa mankhwalawa amaperekedwa pamsika wa pharmacological - 0,5 g, 0,85 g ndi 1 g yogwira ntchito. Kutengera ndi kuopsa kwa hyperglycemia, dokotala amapereka mankhwala omwe amafunikira. Mapiritsi onse a formin angagulidwe m'makatoni a zidutswa 30, 60 kapena 120. Kugwiritsa ntchito kwawo kumatheka pokhapokha ngati adokotala adanenanso (masiku ano azimayi ambiri amagwiritsa ntchito njira yochepetsera thupi).
Njira yoyendetsera ndi kumwa Mlingo wakhazikitsidwa kwa wodwala aliyense payekhapayekha, kutengera magawo ake:
- kuopsa kwa matenda komanso kuchuluka kwa kutsekemera kwa shuga m'magaziꓼ
- gulu la odwala ndi odwala and
- kukhalapo kwa matenda oyanjana.
Musanayambe chithandizo, ndikulimbikitsidwa kuyezetsa magazi ndikuyesa kuti mupeze zoopsa zomwe zingachitike ndikugwiritsa ntchito mankhwalawa.
Mankhwala Formetin, monga lamulo, amatengedwa molingana ndi malingaliro otsatirawa:
- Pakamwa pambuyo chakudya, kumwa madzi ambiri.
- Mankhwala oyambira ayenera kuyamba ndi kuchuluka kwa ntchito yogwira ndipo akhale ma milligram mazana asanu patsiku.
- Pakumapeto kwa nthawi (nthawi zambiri pakadutsa milungu iwiri), adotolo, kutengera zotsatira za mayeso ndi kuchuluka kwa shuga m'magazi, amapanga lingaliro pakusintha kuchuluka kwa mankhwalawa. Tiyenera kukumbukira kuti pafupifupi tsiku lililonse mlingo wa 500 mpaka 1000 mg wa yogwira metformin hydrochloride.
- Kuchuluka kwa mankhwala osokoneza bongo omwe amapezeka patsiku sikuyenera kupitirira 3000 mg ya mankhwala othandizira, kwa anthu achikulire chiwerengerochi ndi 1000 mg.
Mutha kumwa formin kamodzi kapena kangapo patsiku, kutengera mtundu womwe wakhazikitsidwa.
Ngati wodwala akufunika Mlingo wambiri wa mankhwalawa, ndibwino kumawagawaniza kangapo patsiku.
Mawonekedwe olakwika a mankhwala
Mankhwala amatha kusokoneza thupi, kuwonetsa zochita zake zoipa.
Kuti muchepetse chiwopsezo cha kupezeka kwawo, ndikofunikira kutsatira malangizo onse a akatswiri azachipatala.
Ndikulimbikitsidwanso kuti muzolowere zomwe mukudziwa zomwe zimapezeka piritsi.
Zotsatira zazikulu zoyipa zomwe zimachitika chifukwa chotenga mapiritsi a Formetin, mosaganizira mlingo,
- kupezeka kwa mavuto osiyanasiyana ndi m'mimba thirakiti. Izi ndi, zoyambirira, monga kuphwanya msambo ndi kusanza, kutsegula m'mimba, kutuphuka ndi kukomoka pamimba.
- mankhwala kumawonjezera chiopsezo cha anorexiaꓼ
- Kusintha kwa kulawa ndikotheka, komwe kumawonekera pakagwa chitsulo chosemphana ndi chitsulo chamkamwa
- kutsika kwa kuchuluka kwa vitamini B, kumakukakamizani kuti mumwe mankhwala ena owonjezera omwe ali ndi zina zowonjezera za mankhwala osowa
- chiwonetsero cha kuchepa magazi
- ndi bongo wambiri, pamakhala chiwopsezo cha hypoglycemiaꓼ
- mavuto ndi khungu, ngati pali kuwonetseredwa kwa thupi lawo siligwirizana.
Odwala ena amakhulupirira kuti formin ndi antiotic. M'malo mwake, mankhwala sakhala m'gulu la mankhwala otere. Nthawi yomweyo, kwa ana, kugwiritsa ntchito mankhwala kuti athetse hyperglycemia ndi koletsedwa.
Zotsatira zoyipa zimathanso kuchitika chifukwa chamankhwala osayenera kapena podzilanga nokha. Kuphatikiza Fomu ndi zida zina zamankhwala (mwanjira ya mapiritsi, kuyimitsidwa, mayankho a jekeseni amakalasi osiyanasiyana ndi magulu) ndizotheka kokha mwa chilolezo cha katswiri wazachipatala.
Kodi zoletsa ntchito ngati mankhwala ndi ziti?
Kuphatikizana kwa formethine kukuwonetsedwa patsamba lolemba.
Wopangayo amafotokozera anthu onse omwe angakhale ogwiritsa ntchito mwatsatanetsatane za milandu yomwe sikovomerezeka kugwiritsa ntchito mankhwalawa.
Kuphatikiza apo, malangizowa amaperekanso chidziwitso chomwe mankhwala ndi zinthu Formetin zimagwirizana.
Sizoletsedwa kumwa mankhwala ngati zotsatirazi zadziwika:
- Acidosis mu mitundu kapena pachimake.
- Atsikana pa nthawi yobereka mwana kapena yoyamwitsa.
- Odwala a zaka zopuma pantchito, makamaka atatha zaka makumi asanu ndi limodzi ndi zisanu.
- Kusagwirizana ndi gawo la mankhwalawa, chifukwa kuyambitsidwa kwa ziwengo zovuta ndikotheka.
- Ngati wodwala wapezeka ndi vuto la mtima.
- Ndi vuto lapamtima lakale ndi matenda ashuga.
- Ngati hypoxia imachitika.
- Pakusowa kwamadzi, komwe kumayambanso chifukwa cha matenda osiyanasiyana opatsirana.
- Kugwira ntchito kwambiri.
- Matenda am'mimba, kuphatikizapo kukhalapo kwa zilonda.
- Kulephera kwa chiwindi.
Kuphatikiza apo, kuphatikiza kwa chithandizo chamankhwala ndi mowa (mowa pakuwonetsedwa kulikonse) sikovomerezeka.
Ngati wodwala ali ndi ntchito ya impso, chiopsezo chokhala ndi lactic acidosis chitha kuchuluka, popeza kuchuluka kwa lactic acid mthupi kumayamba kudziunjikira.
Ndemanga za akatswiri azachipatala ndi odwala ndi ma analogu
Malongosoledwe amapangidwe a mapiritsi a Foromu ndi kuwunika kambiri kwa ogula akuwonetsa ntchito yake kwambiri.
Kuphatikiza apo, odwala ambiri amawonetsa kulera kosavuta kwa mankhwalawa komanso kusapezeka kwa zovuta zosiyanasiyana.
Formmetin ili ndi mtengo m'mafakitala a ma ruble zana ndipo zimatengera zinthu zingapo.
Zomwe zimakhudza mtengo wa mankhwalawa ndi izi:
- kuchuluka kwa mapiritsi pa paketi iliyonse
- Mlingo wa yogwira mankhwala
- mzinda wogulitsa ndi mankhwala.
Mtengo wa formin ndi dongosolo la kutsika kwambiri kuposa mankhwala ena omwe ali ndi mankhwala othandizira a metformin hydrochloride. Ichi ndichifukwa chake, akatswiri ambiri azachipatala amalimbikitsa kugwiritsa ntchito chida ichi kuti matenda a matenda ashuga asinthe. Ndemanga za madotolo zokhudza kuthamanga kwa shuga m'magazi, kusalolera pachitukuko cha kukana insulini, titilole kunena kuti Formetin ndi njira yosankhira bajeti yomwe imabweretsa zotsatira zabwino.
Mitundu ya formimetin pamsika wama pharmacological imayimilidwa zambiri. Izi zikuphatikiza mankhwala osokoneza bongo omwe ali ndi mankhwala enaake, omwe amatha kukhala osiyana, koma ali ndi vuto lofananalo. Mukafuna cholowa m'malo, muyenera kupeza upangiri wa dokotala yemwe angakupatseni mwayi woyenera.
Mankhwala otsatirawa akuphatikizidwa ndi kuchuluka kwa amafomu amodzi a Fomu:
- Bagomet.
- Glyminfor.
- Glycon.
- Glucophage.
- Langerine.
- Metfogamma.
- Sofamet.
- Metformin.
- NovoFormin.
Mankhwala onse omwe ali pamwambawa ndi ena mwa mapiritsi ochepetsa shuga omwe ali ndi vuto la hypoglycemic. Chofunikira chachikulu ndi metformin hydrochloride. Mankhwalawa sikuti amasiyana ndi Foromu. Kusiyanaku kungakhale mu kuchuluka kwa zoyipa kapena contraindication zomwe zikuwonetsedwa, komanso mtengo wa mankhwalawo.
Nthawi zina, formin imafotokozedwa ngati mankhwala ophatikizika pogwiritsa ntchito mankhwala monga atorvastatin kapena glycine.
Zomwe ndimankhwala opatsirana a shuga zomwe zingathandize kuphatikiza shuga m'magazi, katswiri adzanena mu kanema munkhaniyi.
