Telzap nthawi zambiri imagwiritsidwa ntchito pochiza matenda oopsa. Kuphatikiza apo, adapangidwira kusintha momwe alili odwala omwe ali ndi matenda osokoneza bongo komanso myocardial infarction.
Dzinalo Losayenerana
INN ya mankhwalawa ndi Telmisartan.
Mankhwala Telzap amalembedwa kuti athetse vuto la odwala omwe ali ndi matenda osokoneza bongo komanso myocardial infarction.
ATX
Gulu la ATX: Telmisartan - C09CA07.
Kutulutsa mafomu ndi kapangidwe kake
Mankhwalawa ali ngati mapiritsi. 1 piritsi (40 mg) ili ndi:
- yogwira pophika (telmisartan) - 40 mg;
- zosakaniza zina: sodium hydroxide (3.4 mg), sorbitol (16 mg), meglumine (12 mg), magnesium stearate (2.4 mg), povidone (25 mpaka 40 mg).
Mapiritsi a 80 mg, mawonekedwe ake ndi ofanana, koma kuchuluka kwa zinthu zothandizira komanso zogwira ntchito ndikofunikira.
Zotsatira za pharmacological
Mankhwala amachepetsa mulingo wa aldosterone m'magazi am'magazi, samalepheretsa magwiridwe antchito a ion, kininase II ndipo samathandizira kuletsa kwa renin. Chifukwa cha izi, palibe zotsatira zoyipa zokhudzana ndi zovuta za bradykinin. Mwa anthu omwe ali ndi thanzi labwinobwino, mankhwalawa amachepetsa mphamvu ya II-angiotensin zolandilira. Izi zimatenga maola opitilira 24 ndipo zimatha mpaka maola 50.
Mphamvu ya antihypertensive ya mankhwalawa imayamba patatha maola atatu itatha. Ndi ochepa matenda oopsa, mankhwalawa amachepetsa kuthamanga kwa magazi, onse a diastolic ndi systolic, osakhudza kugunda kwa mtima. Ndi kusiyidwa kwakanema kwa mapiritsi ndi mapiritsi awa, kuthamanga kwa magazi pang'onopang'ono kumabwezeretsa. Wodwala samakumana ndi matenda achire.
Pharmacokinetics
Wotsutsa wa receptor amatengedwa mwachangu kuchokera m'mimba thirakiti pambuyo pakamwa. Kwambiri ndende ya madzi am`magazi amafikira pambuyo 30-90 mphindi pambuyo makonzedwe.
Mankhwalawa amachotseredwa m'matumbo (pafupifupi 97%) ndi impso (2-3%).
Kuthetsa theka-moyo woposa maola 21.
Zizindikiro zogwiritsidwa ntchito
Mankhwala osokoneza bongo amalimbikitsidwa pazinthu zotere:
- ndi zofunika komanso mitundu ina ya matenda oopsa;
- Kuchepetsa zochitika za matenda amtima dongosolo, atherothrombotic chiyambi ndi kufa kwa odwala matenda a shuga mellitus (mitundu iwiri).
Mankhwala tikulimbikitsidwa kuchepetsa matenda a mtima.
Contraindication
Zoletsa kumwa mapiritsi:
- kuphatikiza ndi aliskiren mu kwambiri kuwonongeka kwa impso ndi mitundu yosiyanasiyana ya shuga;
- kuphatikiza ndi ACE zoletsa mu diabetes mtundu wa nephropathy;
- mitundu yolepheretsa yamatenda oyamba;
- Hypersensitivity kuti fructose;
- ntchito yayikulu pakugwira chiwindi
- mkaka wa m'mawere (yoyamwitsa) ndi pakati;
- wodwala zaka zosakwana 18;
- tsankho la munthu lomwe limapezeka mu kapangidwe kamankhwala.
Ndi chisamaliro
Mankhwala amathandizidwa mosamala kuti apangidwe ndi ma pathologies ndi zina:
- stenosis yamitsempha yama impso;
- mitundu yochepa / yofatsa ya kukanika kwa chiwindi;
- zoletsa kugwiritsa ntchito mchere (gome);
- hyponatremia;
- kwambiri ochepa hypotension;
- kusanza ndi kutsegula m'mimba;
- cardiomyopathy (hypertrophic mawonekedwe).
- pachimake mawonekedwe a mtima kulephera;
- mitral / aortic valve stenosis.
Kuphatikiza apo, mankhwalawa amalembedwa mosamala kwa hemodialysis ndi odwala omwe ali mu liwiro la Negroid.
Momwe mungatenge telzap
Mankhwalawa amatengedwa pakamwa (kamodzi patsiku) kamodzi patsiku, mosasamala nthawi yakudya. Mapiritsi ayenera kutsukidwa ndi kapu yamadzi.
Odwala ochepa matenda oopsa, mlingo woyambirira ndi 40 mg / tsiku. Odwala ena amapatsidwa mankhwala 20 mg. Mutha kukwaniritsa izi pomatula mapiritsi pakati. Ngati achire sangathe, ndiye kuti mankhwalawa amayamba kuchuluka. Mlingo wapamwamba ndi 80 mg / tsiku.
Kuchepetsa kugunda kwa mtima, mankhwalawa amayenera kumwedwa 80 mg.
Pankhaniyi, wodwala amafunikira kuwunika mosamala zizindikiro za matenda.
Chithandizo cha matenda ashuga
Odwala omwe ali ndi matenda osokoneza bongo a mellitus ndi CVD pathology, mukamagwiritsa ntchito mankhwalawa, chiopsezo cha kufa mwadzidzidzi kapena kupezeka kwa kulowerera kwa myocardial kumawonjezeka. Chifukwa chake, mankhwalawa amayenera kumwedwa moyang'aniridwa ndi achipatala. Kuphatikiza apo, odwalawa amapimanso mayeso ena, malinga ndi zotsatira za nthawi yomwe mankhwalawo amathandizidwa komanso kuchuluka kwa mankhwalawa amasankhidwa.
Mankhwala amachepetsa kuchuluka kwa shuga m'magazi, motero ndi matenda a shuga, muyenera kumayang'anitsitsa shuga. Zikatero, zimafunikira kusintha kuchuluka kwa insulin.
Zotsatira zoyipa
Mukamagwiritsa ntchito mankhwalawa, mutha kukumana ndi mawonekedwe amtundu wina.
Matumbo
- kutsekula m'mimba / kudzimbidwa;
- kusanza
- kufalikira ndi kuchuluka kwanyumba;
- kulakwira;
- kamwa yowuma.
Hematopoietic ziwalo
- eosinophilia (kawirikawiri);
- kuchepa magazi (m'malo osowa kwambiri);
- thrombocytopenia.
Pakati mantha dongosolo
- kugona kosagona;
- Kuda nkhawa
- mutu
- kugona
- kukomoka.
Kuchokera kwamikodzo
- kulakwitsa kwa impso (kuphatikizapo pachimake mawonekedwe a kulephera kwaimpso).
Kuchokera ku kupuma
- kutsokomola
- zilonda zapakhosi;
- kupuma movutikira.
Pa khungu
- zotupa ndi kuyabwa;
- Edema ya Quincke;
- urticaria;
- erythema ndi eczema;
- poizoni komanso mankhwala osokoneza bongo.
Kuchokera ku genitourinary system
- kusabala
- yafupika libido.
Kuchokera pamtima
- kutchulidwa kuchepa kwa kuthamanga kwa magazi;
- bradycardia;
- tachycardia;
- hypotension wa orthostatic mtundu.
Dongosolo la Endocrine
- hypoglycemia;
- Hyperkalemia
- kusowa kwa mahomoni;
- chiopsezo chotenga matenda chikuwonjezeka.
Mutatha kutenga Telzap, kusowa kwa mahomoni kumatha kuchitika.
Pa mbali ya chiwindi ndi biliary thirakiti
- zotupa ndi chiwindi ntchito.
Matupi omaliza
- mawonekedwe a anaphylactic;
- Hypersensitivity.
Malangizo apadera
Musanagwiritse ntchito mapiritsi, adokotala amamuwuza kuti ayambe kuphunzira, omwe amadziwa kuchuluka kwa potaziyamu ya madzi a m'magazi. Ngati chizindikiro ichi chikuwonjezereka, ndiye kuti kuletsa kwathunthu kumakhazikitsidwa pakugwiritsa ntchito mankhwala a antihypertensive.
Kuyenderana ndi mowa
Zida zomwe zili ndi zakumwa zoledzeretsa zimakhudza kwambiri mitsempha yamagazi. Kuphatikizidwa kwa mankhwalawa ndi zinthu zotere kumatha kuyambitsa zotsatira zosakonzekera, chifukwa chake siziyenera kuphatikizidwa ndi mowa.
Zokhudza mphamvu pakuwongolera njira
Sungani zida zamagetsi zamagetsi ndi magalimoto mukamamwa mankhwalawa mosamala momwe mungathere, chifukwa nthawi imeneyi mutha kukumana ndi kugona komanso chizungulire.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Sizoletsedwa kugwiritsa ntchito mankhwalawa panthawi yapakati. Pa mkaka wa m`mawere, ntchito mankhwalawa, kuyamwitsa kuyenera kuyimitsidwa.
Kukhazikitsidwa kwa Telzap kwa ana
Ndi zoletsedwa kugwiritsa ntchito mankhwalawa kwa odwala ochepera zaka 18.
Gwiritsani ntchito mu ukalamba
Odwala okalamba safuna kusintha kwa mlingo.
The ntchito aimpso kuwonongeka
Odwala omwe ali ndi vuto lowoneka bwino komanso aimpso safuna kusintha kwa Mlingo. Pazovuta zazikulu, mankhwala amatsutsana. Poterepa, wodwalayo ayenera kuwongolera kuchuluka kwa CC m'madzi a m'magazi.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Ndi koletsedwa kumwa mapiritsi pamaso pa matenda opatsirana a m'mimba. Kuphatikiza apo, mankhwalawo amaletsedwa kugwiritsidwa ntchito ndi anthu omwe ali ndi vuto lalikulu la chiwindi komanso zolakwika zina za chiwindi.
Bongo
Zizindikiro za kupitirira muyeso wa mankhwalawa zikusonyeza tachycardia ndi kuchepa kwa magazi. Kizungulire ndi bradycardia kumachitikanso. Mankhwalawa ndi chizindikiro.
Pakachitika zovuta, siyani kumwa mapiritsi ndi kukaonana ndi dokotala.
Kuchita ndi mankhwala ena
Mukaphatikiza mankhwala ndi mankhwala ena, mawonekedwe osiyanasiyana amawonedwa.
Kuphatikiza kophatikizidwa
Sizoletsedwa kuphatikiza mankhwalawo ndi ACE inhibitors mwa odwala omwe ali ndi matenda ashuga. Kuphatikiza apo, ndizoletsedwa kuphatikiza ndi aliskiren.
Mukaphatikiza mankhwala ndi mankhwala ena, mawonekedwe osiyanasiyana amawonedwa.
Osavomerezeka kuphatikiza
Ndiosafunika kuphatikiza mapiritsi ndi thiazide diuretic (hydrochlorothiazide ndi furosemide), chifukwa kuphatikiza koteroko kumatha kudzetsa hypovolemia.
Kuphatikiza komwe kumafunikira kusamala
Ndi munthawi yomweyo kugwiritsa ntchito mankhwala omwe ali ndi kukonzekera kwa lithiamu, kuyang'anira kuchuluka kwa lifiyamu m'madzi amwazi kumafunika. Zomwezi zimagwiranso ntchito ndi potaziyamu mankhwala, ndiye kuti, akaphatikizidwa ndi mankhwala omwe amafunsidwa, wodwalayo ayenera kuwongolera zomwe zili mu plasma yamagazi. Izi zimachitika makamaka kwa odwala omwe ali ndi vuto la chiwindi.
Analogi
Mawu ofananira kwambiri ndi mankhwala:
- Telzap Plus;
- Losartan;
- Nortian;
- Valz;
- Lozap;
- Naviten;
- Telmista;
- Mikardis.
Kupita kwina mankhwala
Mankhwalawa sapezeka.
Kodi ndingagule popanda kulandira mankhwala?
Mankhwalawa amamasulidwa pokhapokha ngati wodwala wamupatsa mankhwala.
Zambiri bwanji za Telzap
Mtengo wa mankhwala umayambira ku ruble 313 pachikwama chimodzi ndi mapiritsi 30.
Zosungidwa zamankhwala
Mankhwalawa ayenera kusungidwa kuti nyama ndi ana ang'ono sangazipeze. Kutentha kwakanthawi - osaposa + 25 ° C.
Tsiku lotha ntchito
Kufikira zaka 2 kuyambira tsiku lopangidwa.
Wopanga
Kampani yaku Turkey "Zentiva" ("ZENTIVA SAGLIK URUNLERI SANAYI VE TICARET").
Ofesi yoyimira Russia ndi kampani yopanga mankhwala Sanofi.
Ndemanga za Telzap
About mankhwalawa amayankha. Izi ndichifukwa chake ntchito yake ndikupezeka kwake.
Madokotala
Sergey Klimov (wamtima wazaka), wazaka 43, Severodvinsk
Ndimalemba mankhwala awa kwa odwala omwe ali ndi matenda oopsa. Amaona momwe telmisartan imathandizira (yogwira mankhwala) komanso mtengo wotsika mtengo. Posachedwa, adalangizanso amayi ake kuti azigwiritsa ntchito mankhwalawa. Kuphatikiza apo, ndidatenga zakudya zake zabwino zopatsa thanzi, chifukwa iye ndi wodwala matenda ashuga.
Anna Kruglova (wochiritsa), wazaka 50, Ryazhsk
Tengani mankhwalawa ndikosavuta - 1 nthawi patsiku. Izi ndizokwanira kuti magazi akhale ochepa momwe magazi amathandizira. Zotsatira zoyipa, odwala amafotokozera kugona, chifukwa chake mukamagwiritsa ntchito mankhwalawa tikulimbikitsidwa kuti musagwire ntchito yoopsa yomwe imafuna kuti anthu azikhudzidwa kwambiri.
Odwala
Dmitry Nebrosov, wazaka 55, Moscow
Ndili ndi matenda oopsa, motero ndayamba kugogoda m'makachisi anga. Chifukwa cha vutoli, silinkagwira ntchito, matumba anawonekera pansi pa maso. Adotolo apereka mapiritsi awa. Thanzi langa linasintha kwenikweni pakatha sabata limodzi ndikumwa. Tsopano ndimakhala ndi ine nthawi zonse, chifukwa izi ndi njira zabwino zopewera.
Igor Kondratov, wazaka 45, Karaganda
Mankhwalawa adathandizira wachibale wanga kuchira matenda obisika. Tsopano ali ndi maonekedwe abwino.
