Mankhwala Clopidogrel C3: malangizo ntchito

Clopidogrel C3 ndi mankhwala antitrobocytic kanthu. Amagwiritsidwa ntchito pochiza matenda a mtima, omwe amadziwika ndi kupanga magazi.

Dzinalo Losayenerana

Clopidrogel.

Clopidogrel C3 - amagwiritsidwa ntchito pochiza matenda amitsempha yama mtima, omwe amadziwika ndi kupanga magazi kuundana.

ATX

B01AC04.

Kutulutsa mafomu ndi kapangidwe kake

Mapiritsi oyera ndi tint wachikasu, wokutira. Chofunikira chachikulu ndi clopidrogel bisulfate. Piritsi limodzi lili ndi 75 mg ya chinthu chachikulu. Zowonjezera: wowuma chimanga, lactose monohydrate, calcium stearate, titanium dioxide, cellcrystalline cellulose.

Bokosi 1 la makatoni amakhala ndi mapiritsi 1 kapena 2 a mapiritsi 10.

Zotsatira za pharmacological

Metabolite yogwira ya clopidogrel imalepheretsa kuphatikiza kwa maselo ambiri (kuthira limodzi maselo angapo am'magazi, zomwe zimatsogolera ku mapangidwe a thrombus), kuyimitsa. Ili ndi kuchepa kwa magazi m'magazi, zomwe zikutanthauza kukula kwa mitsempha yamagazi, potero kusintha magazi.

Clopidogrel C3 imakhala ndi mphamvu ya kuchepa m'magazi, zomwe zikutanthauza kukula kwa mitsempha yamagazi, yomwe imapangitsa magazi kuyenda bwino.

Pharmacokinetics

Mankhwala amatengedwa mwachangu ndi mucous nembanemba am'mimba. Kagayidwe ka zigawo zikuluzikulu za mankhwala kumachitika mu minofu ya chiwindi. Kuchoka kumachitika ndi 50% kudzera mu impso, pafupifupi 46% imatulutsidwa m'matumbo ndi ndowe.

Zizindikiro zogwiritsidwa ntchito

Monga prophylactic popewa zovuta zotsatirazi:

• myocardial infarction;
• ischemic stroke;
• zotumphukira mtsempha wamagazi;
• coronary syndrome;
• angina pectoris.

Mankhwalawa amaperekedwa kwa odwala omwe ali ndi fibrillation ya atgency, pamaso pa chiwopsezo cha kuundana kwa magazi. Kutengera ndi kuopsa kwachipatala, imagwiritsidwa ntchito ngati mankhwala odziimira pawokha kapena palimodzi ndi acetylsalicylic acid.

Ischemic stroke - chizindikiro cha kugwiritsa ntchito mankhwala Clopidogrel C3.

Coronary syndrome - chisonyezo chogwiritsa ntchito clopidogrel C3.

Mankhwala amathandizira kupewa mavuto a myocardial infarction.

Clopidogrel C3 ndikulimbikitsidwa kwa angina pectoris.

Mankhwalawa saloledwa kumwa ndi kukha magazi kwa intracranial.

Mankhwala Clopidogrel C3 amaletsedwa kuti azigwiritsidwa ntchito pakugwinya kwambiri kwa chiwindi.

Mankhwalawa amaletsedwa kutenga ndi zilonda zomwe zimayenderana ndi kupezeka kwa magazi mkati.

Contraindication

Sizoletsedwa kutenga zochitika zotere:

• tsankho kwa munthu zigawo zikuluzikulu za mankhwala;
• kulephera kwambiri kwa chiwindi;
• chilonda, limodzi ndi kutuluka kwa magazi mkati;
• intracranial hemorrhage.

Malire ali ndi zaka 18. Mankhwalawa ali ndi lactose. Ngati wodwala ali ndi vutoli lactose tsankho, ndizoletsedwa kumwa mankhwalawa (chifukwa choopsa kwambiri chokhala ndi vuto lakumaso).

Ndi chisamaliro

Kuwunikira pafupipafupi mkhalidwe waumoyo kumafunikira (kuchita mayeso pafupipafupi ndikuwunika magawo a labotale) pochiza ndi clopidogrel C3 mwa odwala omwe ali ndi zotsatirazi:

• kufatsa komanso kufatsa kwamphamvu kwa chiwindi;
• kusamutsa ntchito;
• kuwonongeka kwamakina, kuvulala kwa ziwalo zamkati;
• matenda omwe ali ndi chiopsezo chotaya magazi.

Momwe mungatenge clopidogrel C3?

Malangizowo akupereka lingaliro labwino pokhudzana ndi kuchuluka kwa mankhwalawa. Kwa odwala akuluakulu - 75 mg 1 nthawi patsiku. Mankhwalawa atha kumwa mosasamala chakudya.

Mankhwalawa atha kumwa mosasamala chakudya.

Chithandizo cha coronary syndrome, angina osakhazikika ndi kugunda kwa mtima ziyenera kuyambitsidwa ndi mlingo umodzi waukulu wa 300 mg wa clopidogrel. Patsiku lachiwiri komanso lotsatira la mankhwala, mlingo ndi 75 mg.

Ndi makonzedwe apakati pa Aspirin, mulingo wa acetylsalicylic acid ndi 100 mg. Mlingo wapamwamba wa Aspirin ungayambitse magazi.

Pachimake myocardial infaration: koyamba mlingo - kukweza 300 mg, ndiye 75 mg. Njira ya mankhwala osachepera mwezi umodzi.

Ndi matenda ashuga

Kusintha kwa Mlingo sikofunikira. Mlingo ndi 75 mg patsiku, njira ya mankhwalawa imapitiliza ndi chiopsezo chachikulu cha thrombophlebitis.

Zotsatira zoyipa za clopidogrel C3

Zotsatira zake zoyipa zimaphatikizapo: kupweteka pachifuwa, zizindikiro zofanana ndi chimfine. Osati: bronchospasm, kukula kwa anaphylactic zimachitika.

Pa mbali ya gawo la masomphenyawo

Nthawi zambiri: ocular hemorrhage, kukula kwa conjunctivitis.

Zotsatira zoyipa za clopidogrel C3 zimaphatikizapo kupweteka pachifuwa.

Mankhwala amatha kuyambitsa conjunctivitis.

Pambuyo kugwiritsa ntchito clopidogrel C3, zizindikilo zofanana ndi fuluwenza zimatha kuchitika.

Potengera momwe mankhwalawo amagwiritsidwira ntchito, bronchospasm ingachitike.

Nthawi zina, mutatha kumwa mapiritsi, mseru komanso kusanza kumatha kuchitika.

Kusakwanira kwenikweni kwa mankhwalawa kumatha kuwonetsa ngati nyamakazi.

Kugwiritsa ntchito mankhwalawa kumatha limodzi ndi kutulutsa magazi.

Kuchokera minofu ndi mafupa

Myalgia, nyamakazi, kukoka kwa minofu, arthralgia.

Matumbo

Kutuluka kwamkati m'mimba, kusokonezeka kwa chopondapo - kutsegula m'mimba, kupweteka pamimba. Zocheperako: Kukula kwa zilonda zam'mimbazi ndi gastritis, kusanza pang'ono komanso kusanza, kutulutsa. Osowa kwambiri: magazi owopsa okhala ndi chiopsezo chachikulu cha kufa, mawonekedwe a kapamba, zilonda zam'mimba kapena zam'mimba.

Hematopoietic ziwalo

Leukopenia, thrombocytopenia, gawo lovuta kwambiri la neutropenia.

Pakati mantha dongosolo

Si kawirikawiri: magazi amkati, omwe amatha kupha. Mutu wam'mutu nthawi, chizungulire, kusintha kwamitundu.

Mukamagwiritsa ntchito mankhwalawa, mutha kumva chizungulire.

Mukatha kugwiritsa ntchito mankhwalawa, mutu umagwa nthawi zambiri, komwe ndi chizindikiro cha zotsatira zoyipa.

Kumbali ya kupuma, mutatha kugwiritsa ntchito mankhwalawa, magazi amatuluka m'mphuno.

Pambuyo kumwa mankhwalawa, hematuria imatha kuchitika.

Mankhwala angayambitse kukula kwa leukopenia.

Glomerulonephritis ndi zotsatira zoyipa za clopidogrel C3.

Kuchokera kwamikodzo

Kukula kwa hematuria, glomerulonephritis, kuchuluka kwa ndende ya creatinine.

Kuchokera ku kupuma

Nthawi zambiri pamakhala magazi ammphuno, nthawi zina - bronchospasm, pneumonitis, magazi m'mapapo, kuoneka magazi m'magazi.

Pa khungu

Nthawi zambiri zoyipa pakhungu: zotupa pansi pa khungu. Pafupipafupi: totupa pakhungu, kuyabwa, mawonekedwe a phenura. Osowa kwambiri: angioedema mtundu edema, mawonekedwe a urticaria ndi zidzolo zotupa, erythema ya mawonekedwe a multiform. Milandu yocheperako: kukulira kwa Stevens-Johnson syndrome, necrolysis yonyansa, mtundu wofiira.

Kuchokera ku genitourinary system

Si kawirikawiri: hematuria. Osowa kwambiri: mawonekedwe a hypercreatininemia kapena glomerulonephritis.

Kuchokera pamtima

Maonekedwe a hematomas, osowa kwenikweni: magazi otupa, kupezeka kwa magazi nthawi yayitali pochita opaleshoni, kutsitsa magazi.

Mukamagwiritsa ntchito mankhwala Clopidogrel C3, mutha kukumana ndi mawonekedwe osayenera ngati kuchepa kwa magazi.

Pali zovuta zomwe zimachitika mutagwiritsa ntchito mankhwalawa ndizotupa pakhungu, kuyabwa.

Momwe thupi limasokoneza mankhwalawa limawonetsedwa ndi edema ya Quincke.

Kumwa mankhwala sikulepheretsa kuyendetsa galimoto.

Matupi omaliza

Kutupa pakhungu, edema ya Quincke, mawonekedwe amtundu wa hematological, mwachitsanzo, mawonekedwe a neutropenia ndi thrombocytopenia.

Zokhudza mphamvu pakuwongolera njira

Mankhwalawa samakhudza chidwi ndi kuthamanga kwa zochita, kapena izi ndi zopanda tanthauzo. Chifukwa chake, kumwa mankhwala sikulepheretsa kuyendetsa magalimoto ndikugwiritsa ntchito njira zovuta.

Malangizo apadera

Ngati ndi kotheka, chitani opaleshoni yomwe mukukonzekera, kutenga Clopidogrel C3 iyenera kuchotsedwa sabata 1 ntchito isanakonzekere. Wodwala akapatsidwa mankhwala aliwonse, ayenera kudziwitsa adotolo kuti akumwa clopidogrel.

Dokotala, popereka mankhwalawa, ayenera kufotokozera wodwalayo kuti magazi aliwonse ataya nthawi yayitali, chifukwa chake, pakuboweka kulikonse kwa magazi, wodwalayo ayenera kulumikizana ndi kuchipatala.

Munthawi yonse ya chithandizo ndi clopidogrel C3, ndikofunikira kuwongolera kuchuluka kwa mapulateleti.

Odwala omwe ali ndi matenda a chiwindi omwe amatha kugwiritsa ntchito nthawi yayitali ya clopidogrel C3, pamakhala chiwopsezo chokhala ndi hemorrhagic mtundu diathesis.

Mankhwalawa ali osavomerezeka kuti agwiritsidwe ntchito ndi odwala omwe masiku opitilira 7 atadutsa kale. Nthawi zina, koma thrombocytopenic purpura imawoneka. Chizindikiro cham'mbali chimatha kuchitika ngati mukugwiritsidwa ntchito kwa nthawi yayitali ngati mukumwa mankhwalawo, komanso mukalandira chithandizo kwakanthawi kochepa.

Pazifukwa zachitetezo, mankhwalawa samaperekedwa kwa anthu osakwana zaka 18.

Clopidogrel C3 sinafotokozeredwe kwa amayi panthawi yapakati komanso panthawi yoyamwitsa.

Mukamagwiritsa ntchito mankhwalawa mukalamba, kusintha kwa mankhwalawa sikofunikira.

Wodwala akaphonya mlingo wotsatira, ndipo maola osakwana 12 atadutsa kuti mankhwalawo sanatenge, mlingo womwe umasowa umatengedwa, kumwa kwinaku kumamwa. Ngati maola opitilira 12 adatha, mankhwalawa amatengedwa nthawi yofananira, mlingo sawonjezeredwa.

Gwiritsani ntchito mu ukalamba

Kusintha kwa Mlingo sikofunikira. Mu kulowetsedwa pachimake kwa myocardial, ndikofunika kusiya mankhwalawa oyamba a 300 mg ndi kumwa mankhwalawa nthawi yomweyo muyezo wa 75 mg tsiku lililonse.

Kupangira Clopidogrel C3 kwa ana

Kafukufuku wazachipatala wonena za chitetezo cha mankhwala mwa ana sanachitike. Pazifukwa zachitetezo, poganiza kuti ndiwovuta kwambiri, mankhwalawa saikidwa kwa anthu osakwana zaka 18.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Zambiri pazakudya za Clopidogrel C3 azimayi omwe ali ndi pakati komanso poyamwitsa sizipezeka. Pankhani imeneyi, mankhwalawa sanatchulidwe pamagulu awa a odwala.

Gwiritsani ntchito ntchito yolakwika ya chiwindi

Kusintha kwa munthu payekha sikufunika.

Pamene aspirin ikaphatikizidwa ndi clopidogrel C3, pamakhala chiopsezo chotaya magazi.

The munthawi yomweyo kuperekedwa kwa clopidogrel C ndi warfarin kumawonjezera magazi nthawi ndi mphamvu yake.

Heparin ndi clopidogrel imatha kutengedwa, koma mosamala chifukwa choopsa chotsegulira magazi ambiri.

Mankhwala osokoneza bongo a clopidogrel C3

Zizindikiro: Kutaya magazi kwa nthawi yayitali ndi chitukuko cha zovuta. Mankhwalawa alibe mankhwala enaake. Kuchiza kumakhala ndi njira zochizira kuti magazi asiye kutuluka. Kuyimitsa zizindikiro za bongo ndi kusintha zomwe zimachitika wodwalayo, misa yam'magazi amathira.

Kuchita ndi mankhwala ena

Kuphatikiza kwina kumafunikira chisamaliro chowonjezera:

1. Kugwiritsa ntchito limodzi ndi Warfarin kumawonjezera nthawi yotaya magazi komanso mphamvu yake.
2. Aspirin: Pali chiopsezo chachikulu chotaya magazi ngati asidi acetylsalicylic atengedwa muyezo waukulu ngati antipyretic.
3. Heparin ndi clopidogrel imatha kutengedwa, koma mosamala chifukwa choopsa chotsegulira magazi ambiri.
4. Kukonzekera kuchokera ku gulu la thrombolytics: pafupipafupi magazi otseguka amafanana ndi omwe amawona odwala omwe ali ndi mlingo umodzi wa clopidogrel.
5. Mankhwala osagwirizana ndi ma antisteroidal: Kafukufuku wa zamankhwala awonetsa kuti kugwiritsa ntchito nthawi yomweyo Clopidogrel ndi NSAIDs kumawonjezera chiopsezo cha kuchepa kwa magazi m'ziwalo zam'mimba. Sizikudziwika ngati kutaya magazi m'matumbo a thupi kumachitika. Mankhwala osagwirizana ndi antioperoidal omwe amaphatikiza ndi clopidogrel amatengedwa mosamala kwambiri.

Kuphatikiza kotetezedwa ndi Clopidogrel Nifedipine, Atenolol, Cimetidine, Phenobarbital, Digoxin, Phenytoin, gulu la calcium channel blockers.

Kuyenderana ndi mowa

Ndi zoletsedwa kumwa zakumwa zochizira pakumwa mankhwalawa ndi clopidogrel.

Analogi

Mankhwala omwe alowa m'malo ndi awa: Plavix, Zilt, Trombo ACC, Atherocard, Float, Lopigrol, Klopilet.

Mutha kusintha mankhwalawa ndi mankhwala monga Thrombo ACC.

Mmalo mwake atha kukhala Zilt.

Monga njira ina, mutha kusankha Plavix.

Klopilet ndi analogue of clopidogrel C3.

Ngati ndi kotheka, mankhwalawa amatha kusintha ndi Aterocard.

Chipangidwe chofananachi ndi Lopigrol.

Kodi pali kusiyana kotani pakati pa clopidogrel C3 ndi clopidogrel?

Palibe kusiyana pakati pa mankhwalawa. Awa ndi mankhwala awiri omwe ali ndi mawonekedwe ofanana komanso mawonekedwe owoneka, opangidwa ndi makampani osiyanasiyana azamankhwala.

Kupita kwina mankhwala

Mankhwala.

Kodi ndingagule popanda kulandira mankhwala?

Ayi.

Mtengo wa clopidogrel C3

Mtengo (Russia) umachokera ku ma ruble 400.

Zosungidwa zamankhwala

Ulamuliro wa kutentha sukwera kuposa 25 ° C. Pamalo pomwe kulibe dzuwa.

Tsiku lotha ntchito

Zaka 2

Wopanga

Russia, Northern Star, CJSC.

Ndemanga za clopidogrel C3

Ksenia, wazaka 32, Tyumen: "Ichi ndi mankhwala abwino. Maphunzirowa a Clopidogrel C3 adayikidwa ndi dokotala kwa agogo anga atadwala matenda a ischemic. Mankhwalawa amawoneka ngati Aspirin pakuwoneka bwino kwake - amapangitsa magazi kukhala ochepa magazi, omwe amachepetsa chiopsezo cha magazi."

Andrey, wazaka 42, Astana: "Ndakhala ndikuchiza matenda a C3 kwa zaka 3. Ndili ndi matenda ashuga, motero kungatheke chifukwa cha thrombosis ndilabwino. Ndiwothandiza. Nditha kunena kuti zimakhudza thupi lonse, ndikupanga magazi. miyezi, ndiye ndimapuma pang'ono ndikuyambiranso. Zaka ziwiri zapitazi kuyambira nditayamba kumwa mankhwalawa zidapita mosavuta pankhani zathanzi komanso thanzi. "

Angela, wazaka 48, Kerch: "Tidatuma Clopidogrel C3 pambuyo poti magazi atapezeka mgazi lamanzere mu mtsempha wakufa. Mwendo wanga udandipweteka pafupipafupi. Mankhwalawa adangondipulumutsa. Sikuti ululu udachoka mwachangu, komanso patapita nthawi magazi Ndidatsimikiza mtima, ndipo ndidaganiza kuti opaleshoni yokha ndi yomwe ingathandize kuthana ndi vutoli. Njira yokhayo, njira yake yokhayo ndikuti simungagule popanda mankhwala a dotolo, ndipo izi sizili bwino nthawi zonse, chifukwa chake ndimayenera kuzigula mtsogolo. "