Pakukakamizidwa kwambiri, Lisinopril ndi Indapamide amagwiritsidwa ntchito pophatikiza. Mankhwalawa amagwirizana bwino, ndipo momwe amamwe amamwera kwambiri. Pakangopita maola 24, kupanikizika kumachepa, ndipo ntchito ya minofu ya mtima imayamba kuyenda bwino. Kutupa kwa madzi kuchokera mthupi kumachulukanso, zotengera zimakula, ndipo mkhalidwe wamthupi umakhala bwino. Kuphatikiza mankhwala kumathandizira kuchepetsa chiopsezo cha zovuta zamtima.
Chikhalidwe cha Lisinopril
Mankhwala ndi a gulu la zoletsa zoletsa za ACE. Zomwe zimagwiritsidwa ntchito ndi lisinopril dihydrate mu kuchuluka kwa 5.4 mg, 10,9 mg kapena 21.8 mg. Mankhwala amaletsa mapangidwe a angiotensin octapeptide, omwe amathandiza kuwonjezera magazi. Pambuyo pakukonzekera, mitsempha imakulitsidwa, kuthamanga kwa magazi kumachepa, ndipo katundu pa minofu yamtima imachepa.
Pakukakamizidwa kwambiri, Lisinopril ndi Indapamide amagwiritsidwa ntchito pophatikiza.
Ndi vuto la mtima, thupi limazolowera kuchita zolimbitsa thupi. Mankhwalawa ali ndi mphamvu ya antihypertensive, amalepheretsa kuwonjezeka kopweteka kwa myocardium ndikuchepetsa chiopsezo cha zotsatira zoyipa m'mitsempha yamagazi ndi mtima. Amachotseredwa mwachangu komanso mokwanira pamimba. Wothandizirayo amayamba kuchita pambuyo pa ola limodzi. Pakadutsa maola 24, zotsatira zake zimachuluka, ndipo mkhalidwe wa wodwalayo umayamba kukhala wabwinobwino.
Kodi Indapamide
Chida ichi chimatanthauzira ma diuretics. Kapangidwe kake kamakhala ndi dzina lofanana ndi 1.5 kapena 2,5 mg. Mankhwalawa amachotsa sodium, calcium, chlorine ndi magnesium m'thupi. Mukatha kugwiritsa ntchito, diuresis imakonda kupezeka pafupipafupi, ndipo khoma lamitsempha limayamba kugonja machitidwe a angiotensin 2, kotero kupanikizika kumachepa.
Mankhwala amalepheretsa mapangidwe aulere mthupi, amachepetsa madzi mu minofu, ndikuchepetsa mitsempha ya magazi. Zisakhudze kuchuluka kwa cholesterol, glucose kapena triglycerides m'mwazi. Amamamwa kuchokera mu chakudya cham'mimba ndi 25%. Pakangotha mlingo umodzi, kupanikizika kumakhalitsa masana. Vutoli limayenda bwino pakadutsa masabata awiri likugwiritsidwa ntchito pafupipafupi.
Kuphatikizika kwa lisinopril ndi indapamide
Mankhwala onse awiriwa amathandizira kuchepetsa kufinya komanso kogwira mtima. Mothandizidwa ndi indapamide, kuchepa kwamadzi kumachitika ndipo zotengera zimapumira. Lisinopril dihydrate imalimbikitsanso kupuma kwamitsempha yamagazi ndikulepheretsa kuchulukana mobwerezabwereza. Kuchiza kovuta kumakhala ndi tanthauzo lambiri.
Lisinopril ndi Indapamide amathandizira pakuchepetsa kuthamanga kwazomwe zimachitika.
Zizindikiro zogwiritsidwa ntchito munthawi yomweyo
Kuphatikizika kwa ntchito kumasonyezedwa ndi kukhathamira kwa magazi kwa nthawi yayitali. Indapamide imachotsanso edema osagwirizana ndi mtima kulephera.
Contraindations ku Lisinopril ndi Indapamide
Sikuloledwa nthawi zonse kuvomereza ndalamazi nthawi imodzi. Kuphatikiza kwa mankhwala kumapangidwa mu matenda ndi zikhalidwe zina:
- mimba
- ukalamba;
- ziwengo zamankhwala;
- mbiri ya angioedema;
- kulephera kwaimpso;
- creatinine mulingo wochepera 30 mmol / l;
- otsika a plasma potaziyamu;
- kulephera kuyamwa lactose;
- kuphwanya kutembenuka kwa galactose kukhala glucose;
- nthawi yoyamwitsa;
- ana ochepera zaka 18;
- matenda a shuga;
- ochepa matenda oopsa.
Sizoletsedwa kutenga nthawi yomweyo ndalama zokhala ndi Aliskiren. Chenjezo liyenera kuchitidwa ndi kuchuluka kwa uric acid m'magazi, matenda a mtima, kuchepa magazi, matenda a mtima komanso matenda a impso. Odwala omwe ali ndi vuto limodzi lamanjenje, ofooka kwambiri, komanso osakhazikika m'magazi amafunika kuchepetsa kudya. Simungayambe chithandizo pamodzi ndi opareshoni, kugwiritsa ntchito mankhwala oletsa kupha, kukonzekera kwa potaziyamu ndi membrane wamatumbo oyenda kwambiri.
Momwe mungatengere Lisinopril ndi Indapamide
Kulandila kumachitika mosasamala kanthu kakudya ka chakudya. Mlingo wa mankhwala zimatengera momwe wodwalayo alili komanso momwe angayankhire pochiza mankhwala osakanikirana.
Musanayambe chithandizo, muyenera kukaonana ndi dokotala komanso kukayezetsa.
Kuchokera pamavuto
Mlingo wovomerezeka tsiku lililonse wa kuthamanga kwa magazi ndi 1.5 mg ya indapamide ndi 5.4 mg wa lisinopril dihydrate. Ndi kulekerera kwabwino, mlingo umatha kuchulukitsidwa pang'onopang'ono. Kutalika kwa mankhwala osachepera milungu iwiri. Zotsatira zimachitika mkati mwa milungu 2-4 ya mankhwala.
M'mawa kapena madzulo
Mapiritsi amatengedwa bwino kamodzi m'mawa.
Zotsatira zoyipa
Panthawi ya makonzedwe, zovuta zina zimachitika:
- chifuwa
- Chizungulire
- kutsokomola
- mutu
- kugwedezeka
- kukomoka
- kukoka kwamtima;
- kamwa yowuma
- kuvutika kupuma
- kuchuluka kwa chiwindi michere;
- Edema ya Quincke;
- kuchuluka kwa shuga m'magazi;
- kuchepa kwa ndende ya chloride m'magazi;
- kugona
- aimpso ndi chiwindi ntchito.
Ngati zizindikiro zomwe zili pamwambazi zikuwoneka, muyenera kusiya kulandira.
Malingaliro a madotolo
Elena Igorevna, katswiri wa zamtima
Kuphatikiza kopambana kwa diuretic ndi ACE inhibitor. Ndiwotetezeka komanso wogwira ntchito kwambiri kuposa fanizo. Kupanikizika kumachepera mkati mwa masabata 2-4.
Valentin Petrovich, katswiri wamtima
Chiwopsezo chochepa cha zotsatira zoyipa. Koma ubwana, kuphatikiza sikumawonetsedwa, ndipo odwala okalamba ndi anthu omwe ali ndi vuto la chiwindi kapena impso angafunikire kusintha kwa mlingo.
Ndemanga za Odwala
Elena, wazaka 42
Ndinayamba kumwa mankhwala a 2 ndi kuchuluka kwa mankhwalawa nthawi yomweyo ndi matenda oopsa - 10 mg ya lisinopril ndi 2,5 mg ya indapamide. Ndinkamwa mapiritsi m'mawa, ndipo mpaka madzulo ndimamva bwino. Kenako kupanikizika kunakwera kwambiri mpaka 140/95 mm. Hg Ndinafunika kuchepetsa mlingo. Malangizowo amalembanso za zotsatira zoyipa kutsokomola ndi mseru. Zizindikiro zimawoneka ngati zikugwiritsidwa ntchito kwa nthawi yayitali.
Wachiroma, wazaka 37
Ndimamwa mankhwala a 2 pakukakamiza. Palibe mavuto. Nthawi zina mumamva chizungulire, choncho muyenera kuyendetsa bwino galimoto.
