Lipantil ndi mankhwala omwe odwala amatha kuchotsa zovuta zoterezi pakugwira ntchito kwa thupi monga hypercholesterolemia.
Dzinalo Losayenerana
Fenofibrate.
Mankhwalawa amathandizira kuchotsa zovuta zotere pakugwira ntchito kwa thupi monga hypercholesterolemia.
ATX
C10AB05.
Kutulutsa mafomu ndi kapangidwe kake
Mutha kugula mankhwalawa mu mtundu umodzi wokha. Awa ndi makapisozi, chilichonse chili ndi 200 mg ya fenofibrate yoyeserera.
Zotsatira za pharmacological
Mankhwala ndi a othandizira okhala ndi lipid-kuchepetsa. Chithandizo chogwira ntchito chimapangitsanso lipolysis komanso kuchotsa lipotrotein ya atherogenic pamadzi am'magazi, omwe amakhala ndi triglycerides yambiri.
Fenofibrate imachepetsa kuchuluka kwa lipids m'thupi la wodwalayo. Chifukwa cha kugwiritsa ntchito mankhwalawa, kuchuluka kwa cholesterol ndi triglycerides kumachepetsedwa.
Odwala omwe apezeka ndi dyslipidemia ndi hyperuricemia angawone momwe mankhwalawo amapezeka mu uric acid m'magazi. Gawo limatsitsidwa ndi pafupifupi 25%. Chifukwa chogwiritsa ntchito mankhwalawa, kuchuluka kwa lipoproteins ochepa kumachepetsedwa. Izi ndizofunikira kwambiri kwa odwala omwe apezeka ndi matenda a mtima (ndi manambala a LDL achulukitsidwa). Kuchuluka kwa cholesterol ya HDL (kachulukidwe kakakulu) kukukulira.
Mankhwala ndi a othandizira okhala ndi lipid-kuchepetsa.
Pharmacokinetics
Kupezeka kwa fenofibrate koyambirira sikumakhazikika mu plasma ya wodwalayo. Fenofibroic acid ndiye metabolite yayikulu yomwe imapangidwa chifukwa cha kuwonongeka. Amamangidwa ku albumin 99%.
Pazitali kwambiri ya mankhwalawa m'magazi amadziwika kuti anali ndi maola 4-5 atatha kumwa. Mlingo wogwira ntchito m'madzi a m'magazi amakhalabe wokhazikika ngakhale atakhala nthawi yayitali. Mukamamwa mankhwalawo ndi chakudya, kuchuluka kwa mayamwidwe kumawonjezeka.
Hafu ya moyo wa mankhwalawa ikuyandikira maola 20. Chidacho chimapukusidwa ndi impso. Ndi hemodialysis, samachotsedwa m'thupi.
Zizindikiro zogwiritsidwa ntchito
Ndikofunikira kuchita mankhwala ndi mankhwala ngati munthu ali ndi hypercholesterolemia ndi hypertriglyceridemia, momwe zakudya, ukhondo komanso masewera olimbitsa thupi alibe zotsatira zake.
Contraindication
Pali nthawi zina pamene sizingatheke kuchitira mankhwalawa. Izi zikuphatikiza milandu iyi:
- matenda a ndulu;
- Phototoxicity kapena photosensitization mankhwalawa a ketoprofen kapena ma fibrate, omwe amapezeka m'mbuyomu wodwala;
- kobadwa nako galactosemia;
- Hypersensitivity yogwira mankhwala.
Simungathe kumwa mankhwalawo ndi ma pathologies a gallbladder.
Ndi chisamaliro
Pathologies a minofu ulusi mu mbiri ya banja, hypothyroidism ndi uchidakwa.
Momwe mungatenge Lipantil
Pokhapokha, adotolo amakupatsani kapu imodzi ya mankhwalawa kamodzi patsiku ndi chakudya. Kutalika kwa chithandizo kumatengera zambiri zoyambirira pa matendawo ndi momwe wodwalayo alili.
Nthawi zambiri, mankhwala aatali amafunika. Potere, wodwalayo sayenera kuyiwala za kufunika kotsatira zakudya zomwe zimatsatiridwa asanalandire chithandizo. Ndikofunikira kukumbukira zolimbitsa thupi.
Pokhapokha pakuyenda bwino kwa mankhwalawa pambuyo pa miyezi itatu kuyambira pomwe munayamba, muyenera kufunsa dokotala kuti akupatseni mankhwala ochepetsa kapena mankhwala ena.
Wodwala mwiniyo ayenera kuwerenga malangizo asanamwe makapu.
Pokhapokha pakuyenda bwino kwa mankhwalawa pambuyo pa miyezi itatu kuyambira pomwe munayamba, muyenera kufunsa dokotala kuti akupatseni mankhwala ochepetsa kapena mankhwala ena.
Ndi matenda ashuga
Ndikofunikira kufunsa dokotala za njira yanji yomwe ingakhale yoyenera kwambiri panjira iliyonse. Dokotala aziganizira zaka za wodwalayo, mbiri yake ya zamankhwala ndi zina.
Zotsatira zoyipa za Lipantil
Mukakhudza mtima wamtima, venous thromboembolism imatha kuonekera. Ngati chimbudzi chikamadwala, chomwe sichachilendo, chimadziwoneka ngati ululu wam'mimba, kutsegula m'mimba, kusanza, kusanza ndi mseru, kapamba, chiwindi ndi ndulu.
Rhabdomyolysis (necrosis ya minofu yolimba), kufooka ndi minyewa kukokana sichiwoneka, zomwe zikuwonetsa kusokonekera kwa minofu ndi mafupa. Rhabdomyolysis ndiyowopsa kwambiri ndipo imafunika kuti madokotala azilowa. Zizindikiro zoyipa zomwe zingakhalepo ndizokhala khola, zotupa pakhungu ndi ming'oma (vuto la khungu), chibayo ndi mutu.
Mwa abambo ndi amayi, zogonana zimatha kukhala zovuta, chifukwa chamankhwala omwe angagwiritsidwe ntchito mu urology ndi gynecology angafunike. Pazaka za 45 ndi kupitirira, njira yapadera yodwala imakhala yofunikira.
Pali chidziwitso pakuwoneka kwa kusintha kwa magawo a zasayansi mwa wodwala, zomwe zimaphatikizapo kuwonjezeka kwa kuchuluka kwa hepatic transaminases, urea ndi creatinine mu seramu yamagazi.
Zokhudza mphamvu pakuwongolera njira
Zotsatira zoyipa zitha kutha kuchitika chifukwa chakuti wodwalayo amakonda kupweteka mutu akamamwa mankhwalawo.
Malangizo apadera
Gwiritsani ntchito mu ukalamba
Palibe zambiri zokhudzana ndi kufunika kosintha kwa mlingo.
Kumwa mankhwala okalamba odwala sikutanthauza kusintha kwa mlingo.
Kupatsa ana
Popeza chidziwitso chokhudzana ndi chitetezo ndi ntchito ya mankhwalawa pochiza ana osakonzekera sichinaperekedwe, madokotala samapereka mankhwala kuti apewe mavuto.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Popeza palibe umboni wokwanira wotsimikizira chitetezo, mankhwalawa sayenera kutumikiridwa pakhungu ndi poyamwitsa.
Mankhwala ochulukirapo a Lipantil
Katemera wa mankhwalawa sanapezekepo. Ngati mankhwala osokoneza bongo amakayikiridwa, chithandizo chamankhwala chimapangidwira ndipo chithandizo chamankhwala chimachitika. Hemodialysis siyothandiza.
Kuchita ndi mankhwala ena
Chithandizo chogwira ntchito cha mankhwalawa chimatha kuyambitsa magazi ngati mumamwa ndi ma anticoagulants.
Mankhwala a cyclosporine, impso ya wodwalayo imatha kusokonekera.
Popanga mankhwala othandizira limodzi ndi HMG-CoA reductase inhibitors, zotsatira zoyipa za minofu zimatha kuperekedwa.
Kuyenderana ndi mowa
Kukana mowa panthawi yothandizira ndikofunikira.
Analogi
Tricor, Fenofibrat Canon ndi zakudya zowonjezera pazakudya.
Kupita kwina mankhwala
Kodi ndingagule popanda kulandira mankhwala?
Popanda mankhwala, mutha kupeza mankhwala.
Mtengo wa Lipantil
Mtengo wa mankhwalawo ndi pafupifupi ma ruble 1000.
Zosungidwa zamankhwala
Kutentha kwanyumba.
Tsiku lotha ntchito
Zaka zitatu
Wopanga
Reciphon Fontaine, Rue de Pre Pothe, 21121, Fontaine le Dijon, France.
Mankhwala amaperekedwa pokhapokha ngati amupatsa mankhwala.
Ndemanga za Lipantil
V.N. Chernysheva, endocrinologist, Kirov: "Mankhwalawa amagwira bwino ntchito polimbana ndi cholesterol yayikulu m'magazi. Izi zimachitika wodwalayo akakhala ndi moyo wosayenera, akudya zakudya zamafuta, palibe masewera okwanira m'moyo wake watsiku ndi tsiku. Pankhaniyi, ndikofunikira kukonza izi. kuphwanya malamulo. "
J.N. Ganchuk, yemwe ndi dokotala wamkulu, Yekaterinburg: "Mankhwalawa amakhudza kwambiri mafuta a cholesterol ndi triglycerides m'magazi a wodwala. Kutalika kwa chithandizo nthawi zambiri sikupitilira muyeso wovomerezeka."
Alina, wazaka 37, Novosibirsk: "Mankhwalawa adathandizira pakufunika kuthetseratu zovuta zaumoyo. Dokotala adandiuza. Nditazindikira kuti sizingatheke kugula mankhwalawo popanda mankhwala kuchokera kwa dokotala. Mankhwalawa adapita kunyumba, sindinayenera kupita kuchipatala, ndipo izi chinthu chofunikira kwambiri. "
Cyril, wazaka 28, Zheleznogorsk: "Ndinkamwa ma kapisozi akafunika kuthandizira matenda a metabolic. Ndikhulupirira kuti amathandizanso thupi, chifukwa palibe zotsatira zoyipa zomwe zimadziwika. Kwenikweni, zonse zidakwaniritsidwa, kotero nditha kuvomereza mankhwalawa "Anthu omwe akufunika kugwiritsa ntchito mankhwalawa.
