Gliformin 1000 ndi mankhwala othandiza kuchiza matenda a shuga a 2 omwe samatengera insulin. Kugwiritsa ntchito bwino glycemia, kumalepheretsa zovuta za matenda ashuga.
Dzinalo Losayenerana
Metformin.
Gliformin 1000 ndi mankhwala othandiza kuchiza matenda a shuga a 2 omwe samatengera insulin.
ATX
A10BA02
Kutulutsa mafomu ndi kapangidwe kake
Piritsi lililonse lili ndi 1000 mg ya metformin hydrochloride, yogwira mankhwala. Kuphatikiza apo, zinthu zomwe zimalepheretsa kuphika ndikuphwanya kapangidwe ka mankhwalawa zimawonjezedwa pakupanga mankhwala.
Zotsatira za pharmacological
Zimalepheretsa njira ya gluconeogenesis m'matenda a chiwindi komanso amachepetsa mphamvu ya kuyamwa kwa glucose. Imawonjezera njira zophatikizira magwiridwe antchito a chinthu ichi m'magazi. Kuchulukitsa chiwopsezo cha zimakhala zathupi kuti insulin.
Metformin siyimakhudzana ndi kaphatikizidwe ka glucose ndipo sikuyambitsa zochitika za hypoglycemia. Amathandizira kuchepetsa thupi, motero mankhwalawa amagwiritsidwa ntchito moyenera pakuchepetsa thupi.
Metformin imachepetsa ntchito ya fibrin.
Pharmacokinetics
Pambuyo pakukonzekera pakamwa, mankhwalawa amayamba pang'onopang'ono kuchokera m'mimba. Bioavailability pafupifupi 60%. Kuchuluka kwa plasma ndende kumafikiridwa pafupifupi maola 2,5 atamwa. Sichigwirizana ndi mapuloteni a plasma. Mankhwala akhoza kudziunjikira tiziwalo tating'ono, minofu minofu, impso ndi chiwindi.
Amachotsa impso m'thupi. Nthawi yomwe kuchuluka kwa mankhwalawa amachepetsedwa m'thupi ndi theka ndi anthu osiyana kuchokera ola limodzi ndi theka mpaka maola 4.5. Kuvetsetsa kwa mankhwala kumatheka ndi vuto lalikulu laimpso.
Zizindikiro zogwiritsidwa ntchito
Mankhwalawa akuwonetsedwa kuti mugwiritse ntchito matenda osokoneza bongo omwe amadalira insulin (pokhapokha pakukonzedwa bwino m'thupi, kuphatikiza shuga komanso kunenepa kwambiri).
Glyformin 1000 ikuwonetsedwa kuti igwiritsidwe ntchito mu matenda osokoneza bongo omwe amadalira insulin.
Contraindication
Otsimikizika muzochitika zotere:
- ketoacidosis;
- chikomokere ndi mtengo;
- pachimake aimpso kulephera;
- matenda owopsa omwe angayambitse kuwonongeka kwa impso;
- kusowa kwamphamvu kwamadzi chifukwa cha kusanza ndi kutsegula m'mimba;
- matenda opatsirana opatsirana;
- pachimake vuto la njala;
- matenda am'mapapo ndi bronchi;
- matenda omwe amatsogolera kukulira kwa minofu ya oxygen, kuphatikiza mphumu, kupuma komanso kulephera kwa mtima;
- kulowererapo kwakukulu ndi kuvulala;
- zinthu zofunika insulin;
- pachimake chiwindi kukomoka;
- poyizoni woledzera;
- gestation ndi nthawi yoyamwitsa;
- Hypersensitivity kuti metformin;
- kugwiritsa ntchito mankhwala a radioisotope ndi othandizira kusiyanasiyana kwa x-ray ndi maginito a resonance;
- Zakudya zochepetsedwa zopatsa mphamvu
Ndi chisamaliro
Amalembedwa kwa anthu omwe ali pachiwopsezo chachikulu chokhala ndi lactic acidosis.
Momwe mungatenge Glyformin 1000?
Mankhwala a hypoglycemic amatha kugwiritsidwa ntchito pakuchepetsa thupi. Kuti muchite izi, tengani theka la piritsi (0,5 g) kawiri pa tsiku. Kugwiritsa ntchito mankhwalawa mu Mlingo waukulu kumabweretsa poyizoni. Njira ya mankhwala ndi masiku 20. Kenako amapuma kwa mwezi umodzi ndikubwereza zomwezo. Ngati mutenga nthawi yocheperako, ndiye kuti wodwalayo amayamba kuzolowera metformin, ndipo mphamvu ya mankhwalawa imachepa.
Kugwiritsa ntchito mankhwalawa sikuwotcha mafuta, koma kumagawa mphamvu mthupi.
Ndi matenda ashuga
Mlingo wa mankhwalawa umaperekedwa palokha. Amatengedwa pakamwa. Choyimira chosankhidwa ndi chizindikiro cha glycemia. Imwani piritsi lonse, osafuna kutafuna. Mlingo wokonzanso wa metformin ndi mapiritsi awiri.
Ndikofunika kuti anthu okalamba atenge piritsi limodzi la Glformin 1000.
Ndikofunika kuti anthu okalamba atenge piritsi limodzi la Glformin 1000.
Momwe zimachitikira kwambiri kagayidwe kake, mlingo wa wothandizirawa umachepa.
Zotsatira zoyipa za Gliformin 1000
Kuphwanya regimen yoyendetsera ndi kumwa, zotsatira zoyipa ndizotheka.
Matumbo
Maonekedwe a nseru komanso kusanza. Odwala amatha kusokonezedwa ndi kakang'ono kosangalatsa kazitsulo kamkati kamkamwa. Nthawi zina kutenga Gliformin kumabweretsa kugwa kwakuthwa, kusasangalala.
Zizindikiro izi zitha kuchepetsedwa ndi ma antacid ndi antispasmodics.
Hematopoietic ziwalo
Nthawi zina, kumwa mankhwalawa kumayambitsa matenda amitsempha.
Kuchokera kumbali ya kagayidwe
Metformin ikhoza kuyambitsa malabsorption a vitamini B12 (cyanocobalamin).
Nthawi zina, zimayambitsa lactic acidosis. Izi zimafuna kusiya ntchito mankhwala.
Kuchokera kwamikodzo
Osadziwika.
Dongosolo la Endocrine
Zotsatira zoyipa kwambiri za metformin, makamaka kumayambiriro kwa chithandizo, ndi hypoglycemia. Zimayamba mwadzidzidzi ndipo zimadziwika ndi pallor, nkhawa, mawonekedwe a thukuta lozizira, chisokonezo. Munthawi yoyambirira yakukula kwake, wodwalayo amatha kusiya izi pakudya lokoma pang'ono.
Ndi kwambiri hypoglycemia, wodwalayo amataya chikumbumtima. Ndizotheka kumutulutsa m'ndende zoopsa zokhazokha pokhapokha ngati akufunika kwambiri.
Matupi omaliza
Pazovuta zomwe zimachitika, khungu limakhala lotupa nthawi zambiri.
Zokhudza mphamvu pakuwongolera njira
Chifukwa mankhwalawa angayambitse hypoglycemia, munthawi ya chithandizo sikofunikira kuyendetsa galimoto komanso njira zovuta kwa anthu omwe amakonda kutsika kwambiri m'magazi a shuga.
Malangizo apadera
Pa mankhwala, impso iyenera kuyang'aniridwa mosalekeza. Ngati kupweteka kwamisempha kumachitika, ndende yamagazi imayendera. Kamodzi pa miyezi isanu ndi umodzi, kuchuluka kwa creatinine kumayendera. Ndi kuchuluka kwazinthu izi, palibe mankhwala omwe adayikidwa.
Masiku awiri asanafike ndi atatha kugwiritsa ntchito radiograph pogwiritsa ntchito mankhwala osiyanitsa, mankhwalawa sayenera kuphatikizidwa.
Pa mankhwala, munthu ayenera kupewa zakumwa zoledzeretsa komanso chilichonse chomwe chilimo.
Pa mankhwala, munthu ayenera kupewa zakumwa zoledzeretsa komanso chilichonse chomwe chilimo.
Kubzala kwa parasitic sikuti kuphwanya mankhwala.
Glyformin Prolong ilibe kusiyana kwakukulu mu pharmacodynamics ndi pharmacokinetics.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Pa nthawi ya pakati, metformin imathetsedwa, ndipo wodwalayo amapatsidwa insulin. Mankhwalawa saloledwa kwa amayi apakati chifukwa chosadziwa za chitetezo chake kwa mwana wosabadwa. Ngati ndi kotheka, kugwiritsa ntchito metformin panthawi yoyamwitsa imasinthidwa kukhala zosakanikirana zochita kupanga.
Kulembera Glformin kwa ana 1000
Kupereka mankhwala awa kwa ana sikulimbikitsidwa.
The ntchito aimpso kuwonongeka
Ndikofunikira kuyang'anira mosamala kuwerenga kwa shuga ndi mkaka wa magazi.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Chifukwa cha vuto la chiwindi, ma lactate indices amayenera kuyang'aniridwa bwino.
Gwiritsani ntchito mu ukalamba
Ndikulimbikitsidwa kuti muchepetse mulingo wochepera.
Mankhwala ochulukirapo a Glyformin 1000
Mankhwala osokoneza bongo a metformin angayambitse kwambiri lactic acidosis yokhala ndi mwayi waukulu wokufa. Chomwe chimapangitsa kuti izi zitheke ndi kudziunjikira kwa zinthu chifukwa chosagwira impso. Wodwala akapanda kuthandizidwa, amakhala atayamba kusokonezeka, kenako amakomoka.
Zizindikiro za lactic acidosis zikawoneka, chithandizo cha metformin chimathetseka mwachangu. Wodwala amagonekedwa m'chipatala. Metformin imathetsedwa mwachangu mthupi kudzera mu dialysis.
Kuchita ndi mankhwala ena
Kuchulukitsa kwa zochitika za hypoglycemic kumawonedwa pakumwa mankhwala nthawi yomweyo ndi:
- kukonzekera komwe kumachokera ku sulfonylurea zosiyanasiyana;
- insulin;
- Acarbose;
- antisteroidal anti-kutupa mankhwala;
- Mao zoletsa, ACE;
- Clofibrate ndi zotumphukira zake;
- Cyclophosphamide;
- opanga beta.
Mankhwalawa amalimbikitsa ntchito za hypoglycemic ndi kugwiritsidwa ntchito molumikizana ndi mankhwala omwe si a antiidal.
Kutsika kwa hypoglycemic zotsatira kumawonedwa pakutenga:
- glucocorticosteroid mankhwala;
- kulera kwamlomo;
- othandizira achifundo;
- Glucagon;
- ma analogu opanga a mahomoni a chithokomiro;
- diuretics ya osmotic ndi kuzungulira;
- Phenothiazine ndi zotumphukira zake;
- analogues ndi zotumphukira za nicotinic acid.
Mankhwala amatha kufooketsa zochita za anticoagulants, makamaka zotumphukira za coumarin.
Kuyenderana ndi mowa
Malangizowo akuwonetsa kuti mankhwalawa sagwirizana ndi mowa, chifukwa amachititsa lactic acidosis kuphatikiza zakumwa zoledzeretsa.
Analogi
Zofananira za mankhwalawa ndi:
- Glucophage;
- Siofor;
- Metformin;
- Fomu.
Kupita kwina mankhwala
Mankhwalawa amaperekedwa pokhapokha atapereka mankhwala.
Mtengo wa Glyformin 1000
Mtengo wapakati wa mankhwalawa ndi ma ruble 160. kwa ma PC 10.
Zosungidwa zamankhwala
Khalani m'malo amdima, kutali ndi ana.
Tsiku lotha ntchito
Yoyenera kugwiritsidwa ntchito mkati mwa miyezi 24.
Wopanga
Yopangidwa ndi Akrikhin Chemical and Pharmaceutical Combine JSC, Russia.
Ndemanga za Gliformin 1000
Madokotala
Inna, endocrinologist, wazaka 50, Moscow: "Mankhwalawa amalembedwa kwa odwala omwe ali ndi matenda a shuga a 2 omwe amavutika kuti azikhala ndi glycemia wokwanira. Mankhwalawa ali ndi zotsatira zabwino, mndandanda wa shuga wamagazi umabwereranso kwina."
Irina, wazaka 45, dokotala wamkulu, Nizhny Novgorod: "Kuti muchepetse kunenepa, ndimapereka mapiritsi a Gliformin 1000 kuphatikiza ndi zakudya zama carb ochepa komanso zama calorie ochepa. Izi zimakuthandizani kuti muchepetse kunenepa kwambiri komanso kuti muchepetse kukula kwa matenda ashuga. zotsatira zake.
Odwala
Ilya, wazaka 52, ku Moscow: "Mothandizidwa ndi mapiritsi a Gliformin, ndizotheka kuyendetsa bwino ma index a shuga. Ndinaona kuti kuyambira koyambirira kwa chithandizo chamankhwala ndimakhala bwino, ndinataya ludzu, kuthamanga kwa magazi kwandibwerera."
Svetlana, wazaka 45, Ivanovo: "Kumwa mapiritsiwa kumapangitsa kuchepetsa matenda a shuga ndikutchingira kuchuluka kwa shuga. Ndimamwa mapiritsi tsiku lililonse ndikuwathandiza."
Kuchepetsa thupi
Tamara, wazaka 38, ku St.