Captopril Sandoz ndiwothandiza, wogwira ntchito mwachangu pochiza matenda oopsa. Amawonetsedwa kumatenda omwe ali ndi chiopsezo cha mtima.
Dzina losalolera
Captopril
Atkh
S09AA01
Captopril Sandoz ndiwothandiza, wogwira ntchito mwachangu pochiza matenda oopsa.
Kumasulidwa mafomu ndi kapangidwe
Amapezeka m'mapiritsi, ali ndi izi:
- mawonekedwewo ndi ozungulira kapena mawonekedwe a tsamba lamasamba anayi;
- khungu ndi loyera;
- pamtunda ndi homogeneous;
- chiwopsezo cha mtanda.
Zimapangidwa ndizosiyanasiyana pazoyambira. Maunitsi amasulidwe, omwe ali pa 6.25, 12,5, 100 mg, ali ndi mawonekedwe ozungulira. Mwanjira ya tsamba lokhala ndi masamba anayi, mafomu okhala ndi 50 ndi 25 mg pazomwe zimagwira.
Atadzaza matuza kwa 10 mlingo. Amamasulidwa m'matumba a makatoni. Malangizowo akuphatikizidwa.
Chigawo chilichonse chomasulidwa chimakhala ndi yogwira pophika ndi zosakaniza zothandizira. Kapangidwe kazinthu zina:
- wowuma chimanga;
- lactose monohydrate;
- ma cellcose a microcrystalline;
- stearic acid.
Mulibe mankhwala osokoneza bongo, imapereka chofunikira chothandizira.
Pharmacological kanthu
Ili ndi tanthauzo lotsogolera. Imalepheretsa kaphatikizidwe ka vasoconstrictor angiotensin II kuchokera ku hemodynamically ofooka angiotensin I. Amachepetsa kubisika kwa aldosterone.
Imalimbikitsa kukonzekera kwa bradykinin, yomwe imakhudza kapangidwe ka vasodilating prostaglandins.
Kugwiritsa ntchito nthawi yayitali kumakhala ndi zotsatira zamtima:
- amachepetsa chisanachitike;
- Amayenda ndi magazi kulowa kwa ischemic mabacteria myocardium;
- kumawonjezera nkhokwe;
- Imachepetsa mapangidwe a hypertrophy, kuchepa kwa lamanzere kumanzere;
- amatanthauzira diastolic ntchito.
Sichimayambitsa Reflex tachycardia. Imalimbitsa magazi othamangitsana, imachepetsa kuphatikizika kwa ma cell.
Mlingo wokwanira wa mankhwalawa chifukwa cha kulephera kwa mtima sayambitsa kusinthasintha kwa magazi. Thandizani kuwonjezera kuchuluka kwa miniti, kukulitsa kulolerako zolimbitsa thupi.
Mopanda tsankho. Ili ndi potaziyamu-woteteza. Zimakhudzanso insulin sensitivity.
Ili ndi nephroprotective kwenikweni. Kuchepetsa mphamvu ya impsontere amathandizira kuchepetsa kukakamira kwa mphamvu. Imalepheretsa kuphatikizika kwa mitsempha yambiri, imagwirizanitsa kapangidwe ndi ntchito ya epithelium.
Zochita za renin-angiotensin zimalengeza kukula kwa thupi poyambanso kumwa mankhwalawo.
Mankhwala
Mankhwala ali mwachindunji kwachilengedwe. Zisakhudze machitidwe a minye renin-angiotensin. Mphamvu ya hemodynamic imalumikizidwa ndi vasodilation, sizitengera kuchuluka kwa renin m'magazi.
Captopril Sandoz amatchulidwa kuti ndi gawo la zovuta kuchitira matenda oopsa.
Kuchotsa msanga. Kukhazikika kwa zochita kumadziwika pambuyo pa mphindi 30. Bioavailability wa mankhwalawa ndiwambiri. Kukonzekera kwa pakamwa kumapereka zotsatira zambiri pambuyo pa ola limodzi. Kutalika kwa kuchitapo kanthu kuchokera pa maola 4 mpaka 12.
Zimapukusidwa mu chiwindi, ndikupanga metabolites osagwira. Wosangalatsa ndi impso. Gawo limodzi la mankhwala limapukusidwa kuchokera m'thupi. Itha kudziunjikira vuto laimpso. Hafu ya moyo wotere umakula tsiku limodzi ndi theka.
Zomwe zimathandiza
Nthawi zambiri amatchulidwa ngati gawo la zovuta chithandizo cha matenda otsatirawa:
- matenda oopsa
- matenda ashuga nephropathy;
- kulephera kwa mtima;
- pachimake coronary thrombosis.
Monga monotherapy imagwira ntchito poyambira magawo a matenda oopsa, kumatha popanda zovuta.
Contraindication
Contraindated mu mimba, yoyamwitsa. Sikugwiritsidwa ntchito mwa ana ochepera zaka 18.
Simungathe kugwiritsa ntchito mankhwalawa ndi:
- mbiri ya angioedema yoyambira kulikonse;
- Hypersensitivity kuti constituent zinthu kapena mankhwala ena a gululi;
- matenda a seramu;
- aldosteronism yoyamba;
- lactose tsankho, lactase akusowa mu thupi;
- Mgwirizano wamitsempha wamagazi wamanjenje kapena steriosis ya impso imodzi.
Wothandizila chifukwa chopsa sangathe kugwiritsidwa ntchito pambuyo pothana ndi impso.
Captopril sagwiritsidwa ntchito mwa ana ochepera zaka 18.
Ndi chisamaliro
Chenjezo liyenera kuchitika mu matenda otsatirawa:
- hypertrophic obstriers cardiomyopathy;
- matenda a shuga;
- scleroderma, systemic lupus erythematosus;
- mitral valavu stenosis, machitidwe orortice;
- chikhalidwe cha hypovolemia;
- chiwindi ndi kulephera kwa impso.
Popereka mankhwala, muyenera kuganizira kugwiritsa ntchito zakudya zopanda mchere, zopatsa thanzi.
Mlingo
Mlingo wothandizila ndi munthu payekha. Ndi matenda a impso, ndikofunikira kuyang'ana kuzidziwitso za creatinine clearance. Zikatero, Mlingo wogwira ntchito bwino umagwiritsidwa ntchito, nthawi yayitali pakati Mlingo.
Ndi myocardial infaration
Mankhwala okhazikika amakupatsani mankhwalawa chifukwa cha kukhazikika kwa wodwala. Yambani kulandira chithandizo chamankhwala ochepa kwambiri a 6.25 mg patsiku. Kuchulukitsa kuvomereza kumachulukitsidwa pang'onopang'ono, kukwaniritsa zoyenera.
Pa kukakamizidwa
Ndikofunikira kuyamba ndi mankhwalawa pogwiritsa ntchito mlingo wochepetsetsa, kuwongolera kulekerera kwa mlingo woyamba. Gawani 12,5 mg kawiri pa tsiku. Kukula kwapang'onopang'ono kwa mlingo kumalimbikitsidwa kuti mukwaniritse zomwe mukufuna. Odwala okalamba amapatsidwa mlingo woyenera wa mankhwalawa.
Matenda osalephera a mtima, musanayambe chithandizo, okodzetsa amathetsedwa kapena mlingo wawo umachepetsedwa.
Kulephera kwamtima
Asanayambe chithandizo, okodzetsa amathetsedwa kapena kuti mlingo wawo umachepetsedwa. Yambirani ndi milingo yovomerezeka yocheperako, yomwe imakula pang'onopang'ono. Kusowa kwa malingaliro oyipa kumakupatsani mwayi wogwiritsa ntchito mankhalawo kwa nthawi yayitali. Mlingo wa tsiku ndi tsiku umagawidwa pawiri.
Ndi matenda ashuga nephropathy
Mlingo woyambirira ndi 75-100 mg wa mankhwala patsiku. Pafupipafupi kugwiritsa ntchito mankhwala ndi madokotala. Kuti mukwaniritse bwino, kusankhidwa monga gawo la mankhwala ophatikizidwa kumasonyezedwa.
Momwe mungatenge Captopril sandoz
Ndi bwino kumwa mankhwalawa 1 ola limodzi musanadye. Mlingo amasankhidwa payekha kutengera matenda.
Pansi pa lilime kapena chakumwa
Njira yothira mankhwalawa imatsimikizika mwakuya kwa vutoli. Ndi chithandizo chomwe mwakonza, mankhwalawa amayenera kumezedwa kwathunthu, kutsukidwa ndi madzi okwanira.
Panthawi yamavuto, mankhwala ochepa amaloledwa.
Zochita za mankhwala zimachitika mwachangu, pakatha mphindi 30. Kuchuluka kwakukulu ndi kukonzekera kwa pakamwa kumawonedwa mu ola loyamba.
Imagwira ntchito nthawi yayitali bwanji?
Zochita za mankhwala zimachitika mwachangu, pakatha mphindi 30. Kuchuluka kwakukulu ndi kukonzekera kwa pakamwa kumawonedwa mu ola loyamba.
Ndingamwe kangati
Ndi njira yochepa. Mlingo umodzi umatengedwa kawiri pa tsiku. Pakuganiza kwa dotolo, kuvomerezedwa patatu ndikololedwa. Kulimbikira kwamankhwala othandizirana kumatheka chifukwa chogwiritsidwa ntchito mwadongosolo komanso kwa nthawi yayitali.
Mavuto a Captopril sandoz
Zotsatira zoyipa ndizosowa, koma zimabweretsa zovuta. Zotsatira zoyipa zambiri sizikufuna kulowerera, zimazimiririka ndi kusiya mankhwala.
M'mimba
Kumwa mankhwalawa kumatha kutsatiridwa ndi kusintha kwa kulawa, kusowa kwa chilimbikitso. Nthawi zambiri pamakhala ululu wam'mimba, mavuto a dyspeptic. Nthawi zina pamakhala kuwonjezeka kwa kuchuluka kwa bilirubin ndi hepatic transaminases.
Ziwalo za hematopoietic
Kugwiritsa ntchito mankhwalawa kwa nthawi yayitali kumayendetsedwa ndi chitukuko cha neutropenia, thrombocytopenia, ndi kuchepa kwa hemoglobin. Izi zimachitika kawirikawiri, sizimangochitika zokha.
Kugwiritsa ntchito mankhwalawa kwa nthawi yayitali kumayendetsedwa ndi kuchepa kwa hemoglobin. Izi zimachitika kawirikawiri, sizimangochitika zokha.
Dongosolo lamkati lamanjenje
Chizungulire, kupweteka mutu nthawi zambiri kumakhala kokwanira masiku oyamba. Chithandizo chapadera sichofunikira. Zotsatira za mankhwalawa zimatha kukhala limodzi ndi kumva kutopa, kusilira, kukula kwa paresthesia, asthenia.
Kuchokera kwamikodzo
Mankhwala angayambitse kuchepa kwa kusefera kwa glomerular. Zoterezi zimafuna kuchepetsa mlingo kapena kusiya mankhwala, kuyang'aniridwa mosamala kuchipatala.
Kuchokera ku kupuma
Kukhosakhota kowuma kumawonekera nthawi zambiri. Mwinanso kukulitsa kwa rhinitis, kumverera kosowa kwa mpweya. Zotsatira zoyipa kwambiri zimaphatikizapo bronchospasm. Ndi osowa.
Pa khungu
Kumwa mankhwalawa nthawi zambiri kumayendetsedwa ndi kuyabwa khungu, kuwoneka ngati zotupa. Kugwiritsa ntchito mankhwala kwa nthawi yayitali kumayambitsa kukula kwa lymphadenopathy. Zomwe zimakonda kwambiri ndi dermatitis ndi urticaria.
Chifuwa
Pali chiopsezo chotukula Quincke edema. Maonekedwe a angioedema mu larynx amawopseza mpweya wabwino. Mankhwalawa amathetsedwa, epinephrine amaperekedwa nthawi yomweyo, ndipo mpweya umapezeka mosavuta.
Mukamayendetsa ndege, muyenera kupewa kuyendetsa magalimoto.
Kukopa pa luso lotsogolera njira
Pewani kuyendetsa magalimoto. Osamachita nawo ntchito yolumikizana ndi chidwi chowonjezeka komanso kulondola kwambiri pophedwa.
Malangizo apadera
Kuchita mankhwala kumafuna kuwunika pafupipafupi magawo a hemodynamic ndi ntchito ya impso.
M'pofunika kuganizira momwe mungakhalire hypovolemia mukamagwiritsa ntchito okodzetsa. Zofanana ndi izi zimawopseza ndi mavuto owopsa a mtima, ngakhale kufa.
Kupewa kukula kwa zovuta kumathandiza:
- kusintha kwa mlingo;
- kuyimitsidwa koyambirira kwa okodzetsa;
- masanjidwewo hemodynamic magawo.
Mitsempha yamkati imayambitsa kukoka kwa mankhwalawa, kuwunika kwamikodzo.
Proteinuria mukamagwiritsa ntchito milingo yayikulu imachepetsedwa kapena imapita yokha.
M'pofunika kupewa nthawi yomweyo makonzedwe a mankhwala okhala ndi potaziyamu.
Mosamala zotchulidwa matenda a zosakanikirana minofu, kuphunzitsa immunosuppressive mankhwala. Ndikofunikira kuwongolera zomwe zili m'maselo oyera ndi maselo ena amwazi.
Kuwunikira pafupipafupi kuchuluka kwa shuga m'magazi kumafunika.
Kukula kwa cholestatic jaundice, kuwonjezereka kwa gawo la hepatic transaminases kumafuna kuchotsedwa kwa mankhwalawa.
Kuchiza ndi mankhwalawa kuyimitsidwa tsiku lisanayambike opaleshoni yokonzekera.
Pa nthawi yapakati, captopril sangathe kugwiritsidwa ntchito.
Ntchito pa mimba ndi mkaka wa m`mawere
Mankhwala ali teratogenic kwenikweni. Pa nthawi yomwe mayi ali ndi pakati sangathe kugwiritsidwa ntchito.
Kutalikirana ndi mkaka wa m'mawere kumalepheretsa kugwiritsa ntchito mankhwalawa panthawi yoyamwa.
Kuyenderana ndi mowa
Kuchita ndi zakumwa zoledzeretsa kumawonjezera mphamvu ya antihypertensive ya mankhwala, zomwe zimayambitsa kuphwanya kwa magazi kwa ziwalo ndi minofu. Zofanana zimawopseza kukula kwa zotupa zam'mimba.
Kugwiritsa ntchito zakumwa zoledzeretsa kumathandizira kuti potaziyamu wachotse thupi mosavuta, kumatha zotsatira zabwino za mankhwalawa pamisempha yamtima.
Mowa umathandizira kuchepa kwamitsempha yamagazi, umakhala ndi poizoni. Mwina kukula kwa orthostatic kugwa.
Bongo wa Captopril sandoz
Kumwa Mlingo waukulu wa mankhwalawa kumayambitsa kusokonezeka kwa ziwalo, ndi chiopsezo ku moyo. Kutsika kowopsa pantchito ya kupopa kwa mtima kumayendera limodzi ndi kusowa kwa mbali yamanzere, kutsika kwa hemodynamics, ndi kukhazikika kwa boma. Zizindikiro zakulephera kwa impso zimawonekera.
Izi zimafuna chithandizo chamankhwala mwadzidzidzi. Tsuka m'mimba. Apatseni achifwamba. Bwezeretsaninso magazi, chitani mankhwala ogwirira ntchito.
Kugwiritsira ntchito kolumikizana ndi okodzetsa kungayambitse kukula kwa hypotension, kuchepa kwa zomwe zili potaziyamu mu seramu yamagazi, ndi hypovolemia.
Mogwirizana ndi mankhwala ena
Kugwiritsira ntchito kolumikizana ndi okodzetsa kungayambitse kukula kwa hypotension, kuchepa kwa zomwe zili potaziyamu mu seramu yamagazi, ndi hypovolemia.
Kugwiritsira ntchito kukonzekera kwa potaziyamu, zowonjezera zakudya zimagwirizanitsidwa ndi chitukuko cha hyperkalemia ndi zovuta zamagulu a impso.
Hypotension yayikulu imayamba chifukwa cha mankhwala omwe amagwiritsidwa ntchito ngati opaleshoni.
Ndizosatheka kuphatikiza kulandila ndi Aliskiren ndi zoletsa zina za ACE.
Kugwiritsa ntchito ndi allopurinol kumabweretsa mawonekedwe a neutropenia, kumawonjezera chiopsezo cha zovuta zoyipa.
Kutsitsa kwa mankhwalawa kumapangidwira ndi beta-blockers, othandizira calcium, ma nitrate, mapiritsi ogona, antipsychotic.
Mankhwala amawonjezera kuchuluka kwa digoxin m'magazi.
Pali chiopsezo cha hypoglycemia mukamayanjana ndi othandizira a hypoglycemic.
Imachepetsa kuchotsedwa kwa kukonzekera kwa lifiyamu, ndikuwonjezera ndende yawo ya plasma.
Mukamalumikizana ndi kukonzekera golide, zotsatirapo zake zimakhala zabwino.
Indomethacin, ibuprofen amachepetsa mphamvu ya mankhwalawa. Kusintha kofananako kumadziwika ndi kugwiritsa ntchito estrogen, kulera kwapakamwa, corticosteroids.
Gwiritsani ntchito ma antacid ndipo chakudya chimachepetsa bioavailability ya mankhwalawa ndi 40%.
Analogi
Mitu ya mankhwala, ofanana ndi kapangidwe kake:
- Kapoten;
- Captopril-Akos;
- Alkadil;
- Epsiron
- Captopril Hexal.
Siyanitsani m'dziko lomwe mudachokera, mayina, mtengo. Sankhani analogue mutatha kufunsa dokotala.
Malonjezo a tchuthi kuchokera ku mankhwala
Yoperekedwa ndi mankhwala.
Kodi ndingagule popanda kulandira mankhwala?
Choletsedwa kuti mugulitse kwaulere.
Mtengo wa Captopril sandoz
Mtengo umasiyana kuchokera ku ma ruble 83 mpaka 135 phukusi lililonse.
Kusungidwa kwa mankhwala
Sungani pamalo otetezedwa ku kuwala ndi chinyezi. Pewani kufikira ana. Kutentha kosungiramo zosaposa + 25˚С.
Tsiku lotha ntchito
Zaka 2 kuyambira tsiku lotulutsa, zomwe zikuwoneka phukusi.
Wopanga
"Salutas Pharma GmbH" (Germany).
Sandoz, Switzerland.
Wopanga Captopril sandoz ndi kampani ya Sandoz, Switzerland.
Ndemanga za madokotala ndi odwala za Captopril sandoz
Eugene, wamtima wazaka 46, Krasnodar
Mankhwalawa amagwira ntchito mwachidule, kulolera bwino. Mtengo wake ndi wololera. Ndikupangira pokhapokha pachitika ngozi. Pazifukwa zina, ndibwino kugwiritsa ntchito zinthu zazitali.
Natalia, wazaka 46, Novosibirsk
Kwa nthawi yoyamba ndidagwiritsa ntchito mankhwala kuti ndisiye matenda oopsa. Imagwira mwachangu, palibe mavuto. Tsopano ndimatenga monga adokotala adanenera.
Lika, wazaka 53, Rybinsk
Ndakhala ndikuvutika ndi matenda oopsa kwa zaka zambiri. Ndinkayesetsa m'njira zosiyanasiyana. Mankhwalawa ndiye abwino kwambiri. Ndimavomereza moyang'aniridwa ndi dokotala. Mogwira mtima pamavuto oopsa, amasintha msanga zinthu zake. Zosachita zoyipa sizimayambitsa.
