Ofloxacin ndi mankhwala otchuka chifukwa ali ndi mawonekedwe osiyanasiyana ogwiritsira ntchito, ndipo kuthandizira kwa mankhwalawa kwatsimikiziridwa osati kokha ndi maphunziro azachipatala, komanso chifukwa cha zomwe odwala adakumana nazo.
Mayina apadziko lonse lapansi
Mankhwala opanga mankhwala amagwiritsidwa ntchito padziko lonse lapansi. Dzinali limalembedwa m'Chilatini kuti Ofloxacin.
Ofloxacin ndi mankhwala otchuka.
ATX
Malinga ndi anatomical, achire komanso mankhwala, mankhwala amatanthauza antimicrobial mankhwala a zonse zochitika. Gululi limaphatikizapo ma antibacterial othandizira a zonse zochitika. Izi zimaphatikizapo quinolones ndi fluoroquinolones, omwe amaphatikiza mankhwalawa. Anapatsidwa nambala ya ATX: J01MA01.
Kutulutsa mafomu ndi kapangidwe kake
Mankhwala ogulitsa mankhwalawa ali ndi mitundu ingapo, iliyonse imapangidwa kuti igwiritsidwe ntchito mkati kapena kwanuko. Chofunikira chachikulu pamitundu yonse ya mankhwalawa ndi chinthu chopangidwa chomwe chimafanana ndi dzina la malonda.
Ndi mankhwala othandizira owopsa. Imagwira mtima polimbana ndi tizilombo toyambitsa matenda ambiri. Zida zina zowonjezera sizikhala ndi zotsatira zochizira ndipo zimagwira ntchito zothandizira.
Mapiritsi
Mapiritsiwo amakhala ndi mawonekedwe a biconvex. Kuphimba kwamafilimu kumasungunuka mosavuta. Mtundu wa mankhwalawo uli pafupifupi woyera. Mlingo wa 1 unit ya antibayotiki akhoza kukhala 200 kapena 400 mg wa chinthu chomwe chikugwira ntchito. Mapiritsi amatengedwa pakamwa. Mankhwalawa amadzaza m'matuza ndi pamatulu a makatoni.
Njira Zothetsera
Wothandizira antibacterial amapezeka mu mawonekedwe a kulowetsedwa. Mankhwala oyera achikasu adayikidwa mumbale zamilazi 100 zamdima zakuda. Kuphatikiza pazomwe zimagwira, mawonekedwe a mankhwalawa amaphatikizapo sodium chloride ndi madzi osalala a jekeseni. 100 ml yankho lili ndi 2 g yogwira ntchito.
Mafuta
Mafutawo amapangidwira zochizira matenda amaso. Amapangidwa mu chubu cha aluminium cha 3 kapena 5. Kuphatikizika kwa mankhwalawa kumaphatikiza ndi mankhwala opangidwa ndi antiotic, komanso zotuluka: petrolatum, nipagin, nipazole. Mafutawo amakhala ndi mtundu woyera kapena wotuwa wachikaso komanso mawonekedwe ofanana.
Zotsatira za pharmacological
Wogulitsa mankhwala amatha kuyimitsa kapangidwe ka enzyme inayake yofunika pakukhazikika kwa DNA yamitundu yosiyanasiyana yothandizira. Kuwonongeka kwa zofunikira za selo la bakiteriya kumatsogolera kuimfa yake. Chifukwa chake, mankhwalawa ali ndi zotsatira zoyambitsa matenda komanso mabakiteriya.
Maantibayotiki amagwira ntchito motsutsana ndi tizilombo tating'onoting'ono tomwe timatulutsa beta-lactamases. Mankhwalawa amatha kuthana ndi kukula kwa atypical mycobacteria. Mankhwala, omwe ndi am'badwo wachiwiri wa fluoroquinolones, ali ndi mawonekedwe osiyanasiyana motsutsana ndi gram-gram komanso microflora yama gram.
Mabakiteriya a Anaerobic nthawi zambiri amakhala osagwiritsa ntchito mankhwala. Treponema pallidum sachita chidwi ndi mankhwalawa.
Pharmacokinetics
Zigawo zikuluzikulu zimatengedwa mwachangu m'magazi kuchokera m'matumbo am'mimba ndipo zimatha kulowa kwathunthu m'thupi. Zinthu zogwira zimalowa m'maselo a ziwalo zamkati, kuphatikiza zomwe zimakhudzana ndi kupuma, kwamkodzo komanso njira zoberekera.
Maantibayotiki amadziunjikira mumadzi onse a mthupi, cartilage of joints and bones.
Kuzindikira kwakukulu kumawonedwa patatha pafupifupi mphindi 60. Mpaka 5% ya mankhwalawa imapukusidwa mu chiwindi. Kuchotsa hafu ya moyo ndi maola 6-7. Pafupifupi 80-90% ya yogwira imachotsedwa m'thupi kudzera impso, gawo laling'ono - ndi bile.
Kodi chimathandiza ndi chiyani?
Chithunzithunzi chochulukirapo chimatsimikiza ntchito yothandizira antimicrobial wothandizila kulimbana ndi matenda oyambitsidwa ndi bacteria. Mankhwala amapatsidwa matenda monga:
- kutupa kwa khutu lapakati, sinusitis, sinusitis, kutsogolo sinusitis;
- chotupa chopatsirana chomwe chimaphiritsa kwamikodzo ndi impso (cystitis, urethritis, pyelonephritis);
- bakiteriya matenda am'mimba;
- yotupa matenda a pharynx ndi kupuma dongosolo (pharyngitis, laryngitis, chibayo);
- pathologies a khungu ndi kuwonongeka kwa minofu yofewa, mafupa ndi mafupa olumikizidwa ndi kukula kwa microflora ya pathogenic;
- genitourinary matenda opatsirana komanso yotupa (colpitis, endometritis, prostatitis, cervicitis, salpingitis);
- zilonda zam'mimbamo za cornea, conjunctivitis, blepharitis, dacryocystitis, balere, matenda ammaso oyambitsidwa ndi chlamydia.
Mankhwala othandizira kawirikawiri amagwiritsidwa ntchito musanachite opaleshoni kuti muchepetse zovuta pambuyo pakuchita opaleshoni.
Contraindication
Mankhwalawa sangathe kugwiritsidwa ntchito ndikuwonjezera chidwi ndi kusalolera kwaumwini pazigawo zake. Mitundu yonse yamasulidwa imaletsedwa panthawi yokhala ndi pakati, nthawi ya mkaka wa m'mawere ndi mwa ana ochepera zaka 18. Mu kupweteketsa mtima komanso kuwonongeka kwa maselo enaake, matenda oopsa a chiwindi, impso ndi mtima, maantibayotiki amatsutsana. Lactose kusalolerana ndi kuwonongeka kwa tendon mukamamwa mankhwala kuchokera ku gulu la fluoroquinolone kumafuna kusankha kwa wothandizila wina kuti athandize matendawa.
Kutenga?
Malangizo kutenga, Mlingo mawonekedwe, Mlingo ndi nthawi ya mankhwalawa mtima ndi dokotala kutengera kuopsa kwa matendawa, zaka za wodwalayo komanso njira zina zothandizira.
Asanadye kapena pambuyo chakudya?
Mapiritsi amatengedwa musanadye kapena nthawi ya chakudya, kumumeza yonse. Mlingo wa tsiku ndi tsiku wa akulu ndi 200-800 mg ndipo umagawidwa kawiri. Kutalika kwa njira ya mankhwala ndi masiku 5-10. Mankhwalawa amayenera kumwedwa patadutsa masiku atatu atatha zizindikiro zazikulu za matendawa.
Yankho la jakisoni limaperekedwa kukapumira kamodzi kwa theka la ola. Mlingo ndi 200 mg. Kusintha kwa chithunzi cha chipatala, wodwalayo amamuthandizira ku mankhwala opaka pakamwa. Ngati ndi kotheka, perekani jakisoni wa 100-200 mg 2 kawiri pa tsiku. Kwa anthu omwe ali ndi kuchepa kwamthupi, mulingo ungathe kuwonjezeka mpaka 500 mg patsiku.
Matenda a Chlamydial a maso amathandizidwa ndi mafuta: 1 cm (pafupifupi 2 mg) ya mankhwalawa amaikidwa mu conjunctival sac kuyambira katatu mpaka kasanu patsiku.
Kodi ndizotheka kumwa mankhwalawa chifukwa cha matenda ashuga?
Odwala omwe ali ndi matenda ashuga amaloledwa kumwa mankhwalawo moyenera kuwunika kuchuluka kwa shuga m'magazi. Mankhwala ochepetsa mphamvu ya mankhwala ochepetsa mphamvu ya insulin angayambitse kwambiri hypoglycemia. Musanayambe kugwiritsa ntchito, ndikofunikira kukaonana ndi dokotala ndikufotokozera zamankhwala omwe munthu amamwa mosalekeza.
Zotsatira zoyipa
Fluoroquinolones ikhoza kuyambitsa zovuta zoyipa, zizindikiro zoyambirira zomwe ziyenera kusiya kugwiritsa ntchito mankhwalawa ndikuwonana ndi dokotala kuti awonenso dongosolo la mankhwalawo chifukwa cha matendawo.
Matumbo
Mankhwalawa nthawi zina amayambitsa nseru, kusanza, kutsekula m'mimba. Kukula kwa cholestatic jaundice, pseudomembranous enterocolitis, komanso kuchuluka kwa ntchito ya hepatic transaminases sikutsutsidwa. Nthawi zambiri odwala amadandaula za kupweteka komanso kusasangalala pamimba.
Hematopoietic ziwalo
Mankhwalawa amaphwanya maupangiri amwazi ndipo angayambitse magazi, agranulocytosis, leukopenia, thrombocytopenia.
Pakati mantha dongosolo
Kuchokera kumbali ya dongosolo lamkati lamanjenje, kukulira kwa chizungulire ndi migraine, kulumikizana kwamiseche, chisokonezo, kutayika kwa makutu kumadziwika. Nthawi zina, munthu amakhala ndi nkhawa komanso mantha kwambiri. Kukhumudwa, kusowa tulo kapena zolota m'maloto, kusokonezeka kwamtundu wamtundu sikusiyidwa.
Kuchokera kwamikodzo
Wothandizila antibacterial amatha kuonjezera urea ndikupangitsa kwambiri interstitial nephritis. Mapiritsi ayenera kumwedwa mosamala, chifukwa kuwonongeka kwa impso kumatha kuchitika.
Kuchokera ku kupuma
Zotsatira zoyipa za kupuma zimawonekera mu mawonekedwe a chifuwa chowuma, bronchospasm komanso kupuma movutikira.
Kuchokera ku minculoskeletal system
Zotsatira zoyipa pamachitidwe a musculoskeletal system ndi musculoskeletal mawonekedwe a mawonekedwe a myalgia, arthralgia. Kuphulika kwa Tendon sikuchotsedwa, makamaka odwala okalamba.
Kuchokera pamtima
Chithandizo cha antibacterial chitha kusokoneza kugwira ntchito kwa mtima. Nkhani za tachycardia, bradycardia, vasculitis ndi kugwa zalembedwa.
Matupi omaliza
Zotsatira zoyipa kwambiri ndizomwe zimayambitsa thupi, monga kuyabwa, redness ya zigawo za epermermis, zotupa pakhungu, urticaria, anaphylactic kugwedezeka, edema ya Quincke.
Malangizo apadera
Chidachi sichikugwiritsidwa ntchito pochiza zilonda zapakhosi ndi chibayo chopumira ndi pneumococci. Kusintha kwa mankhwalawa kumafunika chifukwa cha matenda oopsa a mtima, chiwindi ndi impso.
Ngati mapiritsi amakhumudwitsa pseudomembranous enterocolitis, metronidazole iyenera kuperekedwa kwa wodwala.
Mankhwala osokoneza bongo sayenera kumwa kwa masiku opitilira 60. Pa mankhwala, tikulimbikitsidwa kupewa ma radiation ya ultraviolet.
Kuyenderana ndi mowa
Mankhwala sayenera kugwiritsidwa ntchito molumikizana ndi mowa. Mowa umawonjezera poizoni wazomwe zimagwira ntchito za mankhwalawa komanso zimadzetsa kuyambitsa zovuta zoyipa.
Zokhudza mphamvu pakuwongolera njira
Mankhwalawa amachepetsa ma psychomotor amakhudzana ndi thupi, amawononga mphamvu zakuyendetsa magalimoto ndi maginito ophatikizika. Chifukwa chake, anthu omwe amagwira ntchito m'makampani apamwamba omwe ali ndi zoopsa zowonjezera ndipo oyendetsa pa nthawi ya chithandizo ayenera kusamala kwambiri.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Zinthu zodutsa zimalowa mu zotchinga ndikuwononga kukula kwa mwana wosabadwayo. Zigawo za antibiotic zimachotsedwa mkaka wa m'mawere, zomwe zimatha kuvulaza thanzi la mwana. Pa mimba ndi mkaka wa m`mawere, mankhwalawa contraindified. Ngati mayi woyamwitsa akufunika kulandira chithandizo chamankhwala, mwanayo amamuthandizira zakudya zopanda pake.
Gwiritsani ntchito mu ukalamba
Mukakalamba, mankhwalawa amaperekedwa pazifukwa zathanzi. Mankhwalawa amaperekedwa moyang'aniridwa ndi dokotala. Mapiritsi nthawi zambiri amakhumudwitsa tendon mu odwala okalamba.
Bongo
Kuchulukitsa kuchuluka kwa zovomerezeka zamankhwala kumabweretsa kukula kwa mseru ndi kusanza, kusokonezeka koyanjana, kusokonezeka, kupweteka mutu komanso pakamwa pouma. Palibe mankhwala enieni, chifukwa odwala omwe ali ndi vuto la bongo amapatsidwa mankhwala opatsirana mwa m'mimba komanso othandizira.
Kuchulukitsa kuchuluka kwa zovomerezeka zamankhwala kumayambitsa kuphwanya kuyanjana kwa kayendedwe ndi mutu.
Kuchita ndi mankhwala ena
Mu matenda opatsirana opatsirana komanso otupa, amagwiritsidwa ntchito limodzi ndi Ornidazole kuti athandizire antibacterial. Sitikulimbikitsidwa kuphatikiza ndi mankhwala osagwirizana ndi anticoagulants ndi hypoglycemic, chifukwa zomwe akuchita zitha kupitilizidwa. Methotrexate imakhudzanso katulutsidwe katulutsidwe ka fluoroquinolones, ndikuonjezera poizoni.
Kugwiritsidwa ntchito mosiyanasiyana ndi glucocorticosteroids kumawonjezera chiopsezo chotumphukira kwa tendon, makamaka kwa okalamba.
Maantacid okhala ndi mankhwala okhala ndi chitsulo, potaziyamu, magnesium, aluminium ndi lithiamu, kumalumikizana ndi zigawo zogwira ntchito, amapanga mankhwala osakwanira. Kupumula kuyenera kuchitika pakati pamagawo amtundu wa mankhwalawa.
Kugwiritsa ntchito kophatikizana ndi mankhwala osagwiritsa ntchito mahomoni osavomerezeka sikuthandizidwa kuti mupewe zotsatira za neurotoxic.
Analogi
Pali mankhwala angapo amtundu womwewo, mayina omwe amasiyana kokha ndi ma prefixes omwe amawonetsa wopanga (Teva, Vero, FPO, Adalonjeza, ICN, Darnitsa). Zogulitsa zamankhwala izi ndizofanana ndimankhwala ndi 1 yogwira pophika.
Kuphatikiza apo, mankhwala ochokera ku mndandanda wa fluoroquinolone ndi fanizo la antibayotiki. Ndizotheka kusintha mankhwalawa ndi Norfloxacin, Levofloxacin, Ciprolet. Nthawi zina, antimicrobials amalembedwa pamapiritsi kapena ma ampoules ochokera m'magulu ena: Augmentin, Amoxicillin, Rulid. Koma ndikwabwino kuti musamadziyikire nokha, ndipo poyambira matenda opatsirana, pitani kuchipatala.
Kupita kwina mankhwala
Mankhwala a antibacterial amaperekedwa ndi mankhwala.
Kodi Ofloxacin ndi zingati?
Mtengo wa mankhwala umatengera mtundu wa kumasulidwa ndi wopanga. Zitsanzo zapakhomo ndizotsika mtengo kuposa zakunja. Ku Ukraine, mapiritsi angagulidwe kwa h66nias 11.55; ku Russia, mtengo wamankhwala ndi pafupifupi ruble 30 mpaka 40.
Kusunga mankhwala Ofloxacin
Mankhwalawa amayenera kusungidwa m'malo owuma komanso amdima osapezekera kwa ana firiji.
Tsiku lotha ntchito
Mankhwalawa ayenera kugwiritsidwa ntchito patadutsa zaka ziwiri kuyambira tsiku lomwe linasonyezedwatu.
Ndemanga ya Ofloxacin
Vladislav, wazaka 51, Rostov-on-Don.
Ofloxacin adalembedwa pamaso opareshoni yamiyala ya impso. Zomverera zinali zoyipa: kupweteka mutu pafupipafupi, kusakhazikika kwa magonero, nseru. Koma zovuta pambuyo pa opaleshoni sizinachitike. Sindikudziwa, jakisoni anathandiza, kapena popanda iwo zonse zimayenda bwino.
Fatima, wazaka 33, Nalchik.
Chifukwa cha kuchuluka kwa cystitis, ndinamwa mapiritsi masiku 5. Zizindikiro zadutsa kale ntchito za 2-3. Panalibe mavuto. Mankhwalawa ndi otsika mtengo, koma amagwira ntchito mwachangu komanso moyenera.
Stanislav, wazaka 25, Khabarovsk.
Maso anali amadzi komanso oyenda. Zidapezeka kuti "adagwira" matendawa. Maso akutsikira ndi Ofloxacin adalembedwa. Conjunctivitis adadutsa masiku atatu.
