Momwe mungagwiritsire ntchito mankhwala a Captokana 300?

Invokana 300 - hypoglycemic wodziwika wa mankhwalawa, ndi mankhwala mankhwala a matenda a shuga a mellitus insulin.

Dzinalo Losayenerana

Kanagliflozin.

Invokana 300 - hypoglycemic wodziwika wa mankhwalawa, ndi mankhwala mankhwala a matenda a shuga a mellitus insulin.

ATX

A10BX11 - Kanagliflozin.

Kutulutsa mafomu ndi kapangidwe kake

Pali mawonekedwe amodzi okha - mapiritsi.

Mapiritsi

Mu filimu yamafuta. Gawo lalikulu ndi canagliflozin hemihydrate. Zothandiza: microcrystalline cellulose, anactrous lactose, magnesium stearate.

Mtundu wa mapiritsiwo ndi loyera kapena pafupifupi. Kumbali ina ya chipolopolo kuli cholemba "CFZ". Piritsi limodzi lili ndi 300 mg ya chinthu chachikulu. Madera a Shell: utoto oyera, titaniyumu diwokosi, mowa wa polyvinyl.

Madontho

Fomu yotulutsidwa ikusowa.

Ufa

Sipezeka.

Njira Zothetsera

Fomu yotulutsidwa ikusowa.

Makapisozi

Fomu yotulutsidwa ikusowa.

Pali mtundu umodzi wokha wa kumasulidwa kwa mankhwalawa - mapiritsi.

Mafuta

Palibe mawonekedwe oterowo.

Makandulo

Fomu yotulutsidwa ikusowa.

Zotsatira za pharmacological

Mwa anthu omwe ali ndi matenda a shuga, kuchuluka kwa glucose m'magazi kumachitika chifukwa cha kuthamanga kwa shuga mu impso. Zinthu zodalira sodium, zomwe zimanyamula shuga m'magulu a impso, ndi zomwe zimapangitsa izi.

Chosakaniza chophatikizacho ndicholetsa cha zinthu zomwe zimadalira sodium, kuchepetsa kuyamwa kwa shuga mu impso. Mankhwala amachepetsa kuchuluka kwa impso kuti pakubwera shuga, chifukwa chomwe ndende ya glucose imachepa.

Mankhwalawa amayambitsa osmotic zotsatira, amachititsa kuti mapangidwe a mkodzo apangidwe ndi kuyamwa kwambiri, kuchepetsa kuchepa kwa magazi. Kupititsa patsogolo kwa njira yochotsekera kwa glucose ndikuwonetsa kutulutsa mphamvu kumabweretsa kuchepa kwa zopatsa mphamvu komanso kuwonda.

Pharmacokinetics

Mlingo wa bioavailability ndi 65%. Mafuta ambiri omwe amalowa mthupi ndi chakudya samakhudzanso mankhwala a pharmacokinetic. Amayidulira osasintha kudzera mu impso.

Zizindikiro zogwiritsidwa ntchito

Amalembera odwala omwe ali ndi matenda a shuga a 2. Kuti mupeze mankhwala othandizira, mankhwalawa ayenera kuphatikizidwa ndi zakudya zoyenera komanso kuchita masewera olimbitsa thupi nthawi zonse.

Amagwiritsidwa ntchito ngati mankhwala odziimira okha mu monotherapy, komanso mu zovuta mankhwala osakanikirana ndi mankhwala ena a hypoglycemic sipekitiramu ya kanthu, kuphatikizapo jakisoni wa insulin.

Mankhwala amapatsidwa odwala 2 a shuga.

Contraindication

Milandu yamankhwala yomwe ilandila siingatheke:

• tsankho la munthu payekhapayekha;
• mtundu 1 matenda a shuga;
• ketoacidosis;
• kulephera kwa aimpso, pamene kuchuluka kwa kusefukira kwa impso kumakhala kochepera 45 ml pa miniti;
• kulephera kwambiri kwaimpso;
• kobadwa nako lactose tsankho;
• kulephera kwa mtima;
• mimba
• nthawi yoyamwitsa.

Contraindication wazaka - ndizoletsedwa kumwa mankhwalawa kwa anthu osakwana zaka 18.

Ndi chisamaliro

Kukhalapo kwa mbiri ya matenda ashuga ketoacidosis.

Kumwa mankhwalawa sikungatheke ndi matenda a shuga 1.

Kumwa mankhwalawa sikutheka ndi vuto la mtima.

Kumwa mankhwalawa sikutheka ndi ketoacidosis.

Kumwa mankhwalawa sikutheka ndi kulephera kwa aimpso.

Kumwa mankhwalawa sikutheka ndi kubereka kwa lactose.

Kumwa mankhwala mosamala pamaso pa mbiri ya matenda ashuga ketoacidosis.

Kodi kutenga Invocana 300?

Mlingo wovomerezeka wa mankhwalawa koyambirira kwa mankhwala ndi 100 mg patsiku. Pambuyo pa masiku 7-10 (pokhapokha ngati palibe chizindikiro cham'mbali), mlingowo ungathe kuwonjezeredwa mpaka 300 mg patsiku, womwe umalimbikitsidwa kuti uugawidwe magawo angapo.

Ngati pakufunika insulin yowonjezera, Mlingo wa Invokana uyenera kuchepetsedwa.

Ndi matenda ashuga

Mankhwala a hypoglycemic amatha kumwa onse pamimba yopanda kanthu, ndipo akangodya. Njira yotsimikizika ili m'mawa, pamimba yopanda chakudya asanadye chakudya cham'mawa.

Zotsatira zoyipa za Captokana 300

Zizindikiro zoyipa zimachitika makamaka chifukwa chamankhwala osayenera kapena chifukwa cha kuchuluka kwa mankhwala. Komanso, zovuta zoyipa zimatheka mwa anthu omwe ali ndi matenda osachiritsika omwe amakhala ndi exacerbations.

Kumwa mankhwalawa kungayambitse kuchuluka kwa potaziyamu, creatinine ndi urea, hemoglobin. Mndandanda wazovuta zomwe zimachitika umaperekedwa malinga ndi maphunziro oyendetsedwa ndi placebo.

Matumbo

Kusanza, kudzimbidwa, kuluma kowuma pakamwa.

Pakati mantha dongosolo

Chizungulire Postural, kukomoka.

Kuchokera kwamikodzo

Kukula kwa polyuria, matenda, mawonekedwe a kulephera kwa impso.

Kuchokera ku genitourinary system

Candidiasis balanitis, vulvovaginal candidiasis, vulvovaginitis.

Kuchokera pamtima

Kukula kwa orthostatic hypotension, kuchepa kwa intravascular voliyumu.

Matupi omaliza

Zotupa pakhungu, ming'oma, kuyabwa.

Zotsatira zoyipa za mankhwalawa zimatha kudzimbidwa.

Zotsatira zoyipa za mankhwala atha kukhala urticaria.

Zotsatira zoyipa za mankhwalawa zitha kutha.

Zotsatira zoyipa za mankhwalawa zingakhale ndi nseru.

Zotsatira zoyipa za mankhwala zimatha kukhala vulvovaginitis.

Zokhudza mphamvu pakuwongolera njira

Kafukufuku wazachipatala wonena za kuvuta kwa Attokana pakutha kuyendetsa galimoto kapena kugwira ntchito ndi zinthu zovuta kupanga. Wodwala aliyense ayenera kudziwa kuopsa kwa hypoglycemia, yomwe imachulukana ndi kuphatikiza mankhwala ndi jakisoni wa insulin.

Ngati kutenga wothandizirana ndi hypoglycemic kumayendera limodzi ndi kuchepa kwamitsempha yamagazi, kusakhudzidwa kosafunikira kumatha kuchitika mwa chizungulire, kupweteka kwambiri m'mutu komanso kusokonezedwa chidwi. Pankhaniyi, tikulimbikitsidwa kukana kuyendetsa.

Malangizo apadera

Odwala omwe ali ndi vuto lochepa aimpso amatenga pafupifupi mlingo wa 100 mg koyambirira kwa chithandizo ndi 300 mg nthawi yonseyi. Kuchuluka kwa matenda a impso - kuchuluka kwake tsiku lililonse ndi 100 mg. Ngati mankhwalawa akuloledwa ndi wodwala, kuwonjezeka pang'onopang'ono mpaka 300 mg ndikuloledwa.

Odwala omwe ali ndi vuto la chiwindi (ofatsa pang'ono pang'ono) - mlingo wake sukusinthidwa. Kulephera mwamphamvu kwaimpso - palibe kuvomereza.

Wodwala ataphonya muyezo umodzi, mapiritsi ayenera kumwa nthawi yomweyo akangokumbukira izi. Sizoletsedwa kumwa kawiri pa nthawi.

Pa mankhwala, kuyesa kwa mkodzo kutsimikiza kwa shuga kumakhalabe kwabwino, komwe kumafotokozedwa ndi zozizwitsa za pharmacodynamics ya mankhwala.

Kuyesedwa kwa kuyesedwa kwa glucose ndi kadzutsa kosakaniza kunawonetsa kuchepa kwa glycemia: Mlingo wa 100 mg - 1.5-2.7 mmol, mlingo wa 300 mg - 1 mmol - 3.5 mmol.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Panalibe maphunziro pa azimayi oyembekezera. Palibe chidziwitso chamankhwala omwe amapezeka pakhungu la mayi ndi mwana wosabadwa. Popeza kuipa kwa mankhwalawa pa ziwalo zoberekera, amalephera kumwa mapilitsi pakapita nthawi yayitali.

Sizoletsedwa kumwa mankhwalawa kwa anthu osakwana zaka 18.

Popeza kuipa kwa mankhwalawa pa ziwalo zoberekera, kumwa mapilitsi nthawi yotsitsimutsa ndi zotsutsana.

Odwala omwe ali ndi vuto la chiwindi (ofatsa pang'ono pang'ono) - mlingo wake sukusinthidwa.

Popeza kuipa kwa mankhwalawa pa ziwalo zoberekera, kumwa mapilitsi munthawi ya mkaka wa m'mawere kumatsutsana.

Kulembera Invocan kwa ana 300

Sizoletsedwa kulandira anthu ochepera zaka 18.

Gwiritsani ntchito mu ukalamba

Odwala azaka 75 ndi akulu sayenera kumwa zosaposa 100 mg patsiku. Palibe matenda osatha komanso kulekerera bwino kwa mankhwalawa, kuchuluka kwa mlingo wa mpaka 300 mg ndikuloledwa pazifukwa zachipatala.

Overdose wa Invocana 300

Milandu ya bongo osadziwika sadziwika. Mlingo umodzi wa mankhwala woposa 300 mg umatha kuwonetsedwa ndi kuyipa kambiri.

Chithandizo cha mankhwala osokoneza bongo chimakhala pakuchitapo kanthu pochotsa mankhwalawa mthupi - kutsuka m'mimba, kumwa ma sorbe. Onetsetsani kuti mwawongolera odwala.

Kuchita ndi mankhwala ena

Kuonjezera achire zotsatira za okodzetsa mankhwala.

Mphamvu za insulin katulutsidwe ndi insulin nthawi imodzi ndi Invocana zimatha kuyambitsa kuchepa kwamphamvu kwa plasma glucose, ndikupangitsa hypoglycemia.

Kulandila kwa enzymatic inducers - Phenytoin, barbiturates, Efavirenza, Rifampicin, amachepetsa achire zotsatira za mankhwala.

Kuyenderana ndi mowa

Zosagwirizana ndi zakumwa zoledzeretsa. Kuphatikizika kumeneku kumatha kuyambitsa zovuta zoyipa.

Analogi

Kukonzekera ndi mawonekedwe ofanana - Bayeta, Viktoza, Novonorm, Guarem.

Analogue ya mankhwala Viktoza.

Analogue osokoneza bongo a Guarem.

Analogue ya mankhwala Novonorm.

Kupita kwina mankhwala

Kugulitsa mankhwala.

Kodi ndingagule popanda kulandira mankhwala?

Ayi.

Mtengo wa Invokanam 300

Mtengo umayambira ku ma ruble 2400.

Zosungidwa zamankhwala

Kutentha kopitilira 30 ° C.

Tsiku lotha ntchito

Miyezi 24.

Wopanga

Jansen-Silag S.p.A. / Janssen Cillag S.p.A., Italy

Ndemanga za Invokane 300

Madokotala

Marina, wazaka 46, Moscow, endocrinologist: "Ndimamwa ndekha mankhwalawa. Ndizothandiza, sizikuwoneka ngati othandizira ena. Kuchulukitsa kwa zovuta zotsutsana ndi odwala ndikochepa kwambiri ngati mumamwa mankhwalawo molondola ndikuwerengedzera molondola."

Eugene. Wazaka 35, Odessa, endocrinologist: "Odwala ambiri amawopa mtengo wa mankhwalawo. Inde, mankhwala ochokera ku opanga aku Italy ndi okwera mtengo kuposa othandizira kunyumba, koma mankhwalawa ali ndi chiopsezo chochepa chotenga matenda a hypoglycemia ndipo amathandizira odwala onenepa kuti apewe zovuta, zomwe, chifukwa chake, zitha kusintha vutoli komanso kupewa "

Odwala

Anna, wazaka 37, ku St. Petersburg: "Mankhwala, ngakhale anali okwera mtengo, koma ogwira ntchito. Mankhwalawa amachepetsa shuga m'magazi. Mosiyana ndi mankhwala ambiri omwe amayi anga ankayesera matenda a shuga, sizimayambitsa hypoglycemia. "palibe mawonekedwe. Ndi njira yabwino, koma chifukwa cha mtengo wake, kugwiritsidwa ntchito kwake kumakhala kovuta."

Andrei, wazaka 45, Omsk: "Ndidamwa mankhwalawa kwa milungu itatu, nditayamba kudwala mutu, ndimadwala, ndikupsinjika. Kusintha kwa mankhwalawo kwakanthawi kochepa, koma kunawonekeranso. .

Elena, wazaka 39, Saratov: "Ndili ndi Invocana 300, ndimagwira mankhwalawa kwa nthawi yayitali, zomwe zimachitika ngati zotsatira zoyipa. Koma ngakhale matenda osasangalatsa ngati amenewa anali oyenera chifukwa mankhwalawa adapereka, ndipo ndiyofunika ndalama. Ndisanamwe mankhwala ena. koma onse omwe ali ndi mafunde osiyanasiyana adatsogolera ku hypoglycemia. Ndipo izi siziri. "