Amoxicillin madzi: malangizo ntchito

Ambiri molakwika amayang'ana madzi a amoxicillin mu mankhwala. Koma madzi ndi mtundu wina wa mankhwalawo. Amoxicillin amapezeka mu mawonekedwe a granules omwe cholinga chake ndi kukonzekera kuyimitsidwa pakamwa.

Mitundu yomwe ilipo ndi kapangidwe kake

Mankhwalawa amapangidwa mwanjira ya mapiritsi, makapisozi kapena granules. Mitundu yonse yomasulidwa imapangidwira kukonzekera pakamwa, popeza chinthu chogwira thupi chimalowa m'thupi kudzera m'mimba.

Amoxicillin amapezeka mu mawonekedwe a granules omwe cholinga chake ndi kukonzekera kuyimitsidwa pakamwa.

Makapiritsi ndi mapiritsi amalembedwa pa 250 ndi 500 mg. Fomu ya granular imapangidwira kukonzekera kuyimitsidwa kwa ana.

Chomwe chimagwira ndi amoxicillin trihydrate m'magulu osiyanasiyana, zomwe zimatengera mawonekedwe omwe amasulidwa.

Dzinalo Losayenerana

Dzinalo losavomerezeka padziko lonse lapansi ndi Amoxycillin (Amoxycillin).

ATX

Code ya ATX: J01CA04.

Zotsatira za pharmacological

Amoxicillin ali ndi bactericidal komanso antibacterial. Ndi penipillin ya aminobenzyl yomwe imatulutsa bactericidal chifukwa choteteza kuphatikizika kwa khoma la bakiteriya.

Pharmacokinetics

The bioavailability wa amoxicillin amasiyana malinga ndi Mlingo ndipo akhoza kukhala 75 - 90%. Ndi makonzedwe apakamwa a 500 mg, kuchuluka kwake kwa plasma kumachokera ku 6 mpaka 11 mg / L. Mukatenga Cmax, plasma imapangidwa mkati mwa 2 maola.

15-25% ya amoxicillin amapanga mgwirizano wokhala ndi mapuloteni a plasma. Amadziwika ndi kulowa mwachangu m'matumbo a m'mapapo, katulutsidwe a bronchi, mkodzo, bile ndi madzimadzi amkatikati. Ngati manitsowo sanatsitsidwe, ndiye kuti kupsinjika kwa chinthu chomwe chimagwira mu madzi am'magazi chitha kufika 20% ya kachulukidwe kake mu plasma. Thupi limatha kudutsa chimbudzi ndikudutsa mkaka wa m'mawere yaying'ono.

Kuchokera pa 60 mpaka 80% ya mankhwala omwe amagwiritsidwa ntchito amachotsedwa m'thupi ndi impso momwe iwonso adalowetsedwera.

Palibe oposa 25% ya mankhwalawa omwe amapezeka mu metabolism, amapanga penicilloic acid wosagwira. Kuchokera pa 60 mpaka 80% ya zinthu zonse zomwe zimatuluka mthupi ndi impso zimayamwa chimodzimodzi. Izi zimatha pafupifupi maola 7. Mtundu waung'ono wa chinthucho umathiridwa mu ndulu.

Zomwe amoxicillin zimathandizira

Kwa ana, mankhwalawa amalembera matenda otere:

1. Matenda opatsirana.
2. Matenda a pyelonephritis.
3. Purulent tonillitis (aakulu).
4. Mitundu yosiyanasiyana ya bronchitis.
5. Pharyngitis, laryngitis.
6. Furunculosis.

Amoxicillin imagonjetsedwa bwino ndi chotchinga cha histoeticological, ndikupanga bwino ndende ya achire.

Ndiwothandiza kwambiri matenda opatsirana a machitidwe a thupi:

• dongosolo la genitourinary;
• GIT (kupatula matumbo apansi);
• matenda a pakhungu (furunculosis, dermatitis);
• chapamwamba kupuma thirakiti (pharyngitis, pachimake otitis media, angina, bronchitis, pulmonary abscess.

Amoxicillin amagwiritsidwa ntchito pochiza pyelonephritis.

Laryngitis ndi chisonyezo chokhazikitsidwa ndi Amoxicillin.

Pharyngitis ndi chisonyezo chokhazikitsidwa ndi Amoxicillin.

Mankhwala amagwiritsidwa ntchito pochiza furunculosis.

Amoxicillin ndi mankhwala zochizira angina.

Amoxicillin amagwiritsidwa ntchito pofuna kuchiza matenda a bronchitis.

Amoxicillin amachita bwino pachimake otitis media pakati khutu.

Amalembera mankhwalawa amitundu yonse ya chinzonono, salmonellosis, matenda a Lyme. Ndi matenda otere, kudzipereka nokha koletsedwa. Mlingo wofunikira wa mankhwala mu mawonekedwe a trihydrate ungathe kutumizidwa ndi dokotala malinga ndi zotsatira za mayeso.

Ndi matenda oopsa a matenda opatsirana, Amoxicillin ayenera kugwiritsidwa ntchito limodzi ndi clavulanic acid. Pankhaniyi, phwando likhoza kuchitika yonse mu mawonekedwe a mapiritsi, ndi ma jakisoni.

Ndizovuta kunena kuchokera ku zomwe Amoxicillin ndiyothandiza kwambiri. Zonse zimatengera momwe thupi limakhalira, kuuma kwa matendawo komanso mlingo woyenera.

Contraindication

Contraindations akuphatikiza:

1. Hypersensitivity mankhwala.
2. Mankhwala osokoneza bongo a penicillin ndi cephalosporin (mtanda ziwengo).
3. Matenda mononucleosis.
4. Khansa ya m'magazi.

Zoyipa zingapo zingaphatikizeponso:

1. Zaka zosakwana 3.
2. Ine trimester wa mimba.
3. Nthawi yochepetsetsa.
4. Kulephera kwakukulu kwaimpso.
5. Kuphwanya dongosolo la chimbudzi.
6. Mphumu ya bronchial.
7. Mbiri ya anti -otic colitis (mbiri).

Amoxicillin amatsutsana mu mphumu.

Ine trimester ya mimba ndi kuphwanya kumwa mankhwala.

Kulephera kwa impso ndi kuphwanya kukhazikitsidwa kwa mankhwala opha tizilombo.

Ana osaposa zaka 3 sanakhazikitsidwe Amoxicillin.

Matenda mononucleosis ndi kuphwanya kugwiritsa ntchito Amoxicillin.

Ndi matenda a herpes, kugwiritsa ntchito Amoxicillin sikuti kungothandiza, komanso kuvulaza.

Mukamamwa amoxicillin ndi clavulanic acid, vuto la chiwindi limachitika.

Ndi kufanana kwa amoxicillin ndi clavulanic acid, kuphatikiza pa zolembedwa zotsutsana, vuto la chiwindi limatha.

Muyenera kudziwa kuti amoxicillin, komanso maantibayotiki ena, amagwiritsidwa ntchito pochiza matenda okhawo omwe amayambitsidwa ndi ntchito ya mabakiteriya. Ndi matenda opatsirana ndi ma virus (herpes, chimfine, SARS), sikuti ndi osathandiza, komanso owopsa.

Momwe mungagwiritsire amoxicillin

Njira ya achire ndi mlingo amakhazikitsidwa payekhapayekha.

Kukonzekera 100 ml ya kuyimitsidwa, onjezerani madzi oyeretsedwa pamzera wololeza (kapena 74 ml) m'botolo yokhala ndi granules ndikugwedezeka.

Akuluakulu ndi ana opitirira zaka 10 ndi masekeli oposa 40 makilogalamu amatengedwa pa 2 scoops (500 mg iliyonse) katatu pa tsiku. Woopsa matenda, mlingo ukuwonjezeka 1 g (4 scoops) katatu patsiku. Mlingo wapamwamba tsiku lililonse ndi 6 g.

Ndi matenda ashuga

Kuyimitsidwa kwakhala ndi mawonekedwe ake, omwe amayenera kukumbukiridwa kwa odwala omwe ali ndi matenda ashuga.

Kwa odwala matenda ashuga, pa chithandizo cha matenda opatsirana a genitourinary thirakiti, Amoxicillin clavulanate 500/125 mg 3 katatu patsiku amasonyezedwa pakamwa. Kutalika kwa chithandizo ndi masiku 5.

Amoxicillin angathe kumwedwa mosasamala zakudya.

Musanadye kapena musanadye

Chakudya sichimakhudza mayamwidwe. Momwemo, imatha kumwa mosasamala zakudya.

Masiku angati kumwa

Njira ya mankhwala amatenga masiku 5 mpaka milungu iwiri. Imwani mankhwalawa kwa masiku osachepera atatu atatha kuonekera kwa matendawa.

Zotsatira zoyipa za amoxicillin

Mankhwala nthawi zambiri amaloledwa. Nthawi zina, zotsatira zoyipazi zingachitike:

• conjunctivitis;
• malungo
• kusintha kwa kapangidwe ka magazi, kuchepa magazi;
• candidiasis;
• colpitis;

Chithandizo chogwira ntchito chimatha kutsitsa kuchepa kwa kapangidwe ka vitamini K.

Kugwiritsa ntchito mankhwalawa kungapangitse kuchepa kwa index ya prothrombin.

Matumbo

Mavuto monga mseru, dysbiosis, dyspepsia, kutsekula m'mimba, stomatitis imatha kuchitika.

Pakati mantha dongosolo

Zotsatira zoyipa zamkati mwa dongosolo lamanjenje zimatha kuwonetsedwa ndi kupweteka mutu, kusowa tulo, kukwiya, nkhawa, kusokonezeka.

Atamwa mankhwalawa, odwala ena amakhala ndi tachycardia.

Pambuyo pa kumwa Amoxicillin, mutu umayamba kupweteka nthawi zambiri, chomwe ndi chizindikiro cha zotsatira zoyipa.

Pa mankhwala, kusowa tulo kumachitika.

Thupi lawo siligwirizana mankhwalawa limasonyezedwa ndi urticaria.

Mukamagwiritsa ntchito mankhwalawa, mutha kukumana ndi mawonekedwe oyipa monga conjunctivitis.

Zosakwanira zimachitika mthupi la mankhwalawa.

Mukatha kugwiritsa ntchito mankhwalawa, mbali ina monga rhinitis imadziwika.

Kuchokera ku kupuma

Pa mbali ya kupuma kwamphamvu, mbali zoyipa monga rhinitis zimadziwika.

Kuchokera pamtima

Zotsatira zoyipa mwanjira ya tachycardia zitha kuchitika.

Matupi omaliza

Mankhwalawa amatha kuyambitsa mitundu yosiyanasiyana ya chifuwa, monga hyperemia, edema, urticaria, dermatitis, anaphylactic.

Malangizo apadera

Mukamamwa mankhwalawa, muyenera kutsatira malangizo ndi malingaliro a dokotala. Izi sapangira kuti zizigwiritsidwa ntchito ngati prophylactic. Ngati simutsatira malamulo a mankhwalawa, ndiye kuti mabakiteriya amatha kuzolowera zomwe zimachitika chifukwa cha mankhwalawo. Kugwiritsa ntchito kwake pambuyo pake sikungathandize.

Momwe mungaperekere ana

Nthawi zambiri, kuyimitsidwa kumalembedwa kwa ana osakwana zaka 10.

Ana osakwana zaka 2 ndi kulemera mpaka 10 makilogalamu - 0,5 kuwonjezeka katatu pa tsiku (kapena pamlingo wa 20 mg / kg patsiku la 3 waukulu). Ana a zaka zoyambira 2 mpaka 5 masekeli 10 mpaka 20 - 0,5 mpaka supuni 1 yoyesedwa (125 mpaka 250 mg / 5 ml) katatu patsiku. Ali ndi zaka 5 - 10 wazakudya zolemera makilogalamu 20 mpaka 40, makaponi 1 mpaka 2 a 2 (500 - 500 mg) ayenera kumwedwa katatu patsiku. Pafupifupi tsiku lililonse ana kwa zaka 2 mpaka 10 ndi 20-40 mg / kg pa thupi patsiku 3 waukulu.

Kwa ana akhanda ndi ana mpaka miyezi itatu, mlingo waukulu kwambiri wa tsiku ndi tsiku ndi 30 mg / kg patsiku la thupi kwa maola awiri aliwonse a 12.

Pa mkaka wa m`mawere, amoxicillin madokotala salimbikitsa kutenga.

Pankhani ya mankhwala osokoneza bongo, kutsegula m'mimba kwambiri kumachitika.

Pofuna kuthana ndi vuto la bongo, hemodialysis imagwiritsidwa ntchito.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Pa nthawi yoyembekezera, mankhwalawa amawonetsedwa molingana ndi zisonyezo, kupatsidwa zovuta zomwe zingayambitse mwana wosabadwayo. Kafukufuku wokhudza zotsatira za thupi la mwana pakukula kwa fetasi sanachitike, chifukwa chake, kusamala kuyenera kuchitika pakumwa mankhwala.

Panthawi yoyamwa, madokotala samalangiza kuti amwe mankhwalawa, chifukwa amalowa m'matumbo a mwana ndipo amatha kupweteketsa mtima kwambiri.

Bongo

Pakakhala vuto la bongo, kutsegula m'mimba kwambiri kumatha. Mankhwalawa ndi chizindikiro. Nthawi zambiri amagwiritsa ntchito hemodialysis.

Kuchita ndi mankhwala ena

Ndi zoletsedwa kuphatikiza metronidazole ndi amoxicillin panthawi ya mankhwala ali mwana. Wopanga mankhwalawa akuwonetsa kuti singagwiritsidwe ntchito osapitirira zaka 3, koma pochita ana omwe amagwiritsa ntchito mankhwalawa amagwiritsa ntchito mankhwalawa kuchiza ana a zaka zoyambirira.

Sizoletsedwa kumwa mankhwalawa nthawi imodzi ndi zinthu ndi kukonzekera:

1. Njira zakulera za pakamwa zokhala ndi estrogen.
2. Maantibayotiki (cycloserine, rifampicin, vancomycin, etc.).
3. Mankhwala a Bacteriostatic (tetracyclines, lincosamides, macrolides, etc.).
4. Maanticoagulants (mphamvu ya anticoagulants yosadziwika imatsitsidwa).
5. NSAIDs (acetylsalicylic acid, indomethacin, phenylbutazone, etc.).
6. Aminoglycosides.
7. Kaolin.
8. Allopurinol ndi ma antacid.

Amoxicillin saloledwa kugwiritsidwa ntchito molumikizana ndi njira za kulera zomwe zimakhala ndi estrogen.

Amoxicillin nthawi imodzi ndi allopurinol amaletsedwa.

Ndi zoletsedwa kugwiritsa ntchito mankhwalawa limodzi ndi mowa, popeza sizigwirizana.

Kuyenderana ndi mowa

Ndi zoletsedwa kugwiritsa ntchito mankhwalawa limodzi ndi mowa, chifukwa sizigwirizana komanso zimakhudza chiwindi, zomwe zimatha kupha. Pamapeto pa maphunzirowa, ndikofunikira kumwa mowa kwa masiku 7 mpaka 10.

Analogi

Mayina otsatirawa, omwe ali ndi mankhwala amoxicillin, angatchulidwe chifukwa cha ma analogu opangidwa ndi mayiko osiyanasiyana:

1. Amoxillate.
2. Apo-Amoxy.
3. Amosin.
4. Amoxisar.
5. Bactox.
6. Gonoform.
7. Grunamox.
8. Danemox.
9. Ospamox.
10. Tysil.
11. Flemoxin solutab.
12. Hikontsil.
13. Ecobol.
14. E-mox.

Kupita kwina mankhwala

Ndi mankhwala.

Kodi ndingagule popanda kulandira mankhwala?

Tchuthi chotsutsana ndi choletsa sichimaletsedwa.

Mtengo

Mtengo wa makapisozi pokonzekera kuyimitsidwa kumasiyana kuchokera pa 106 mpaka 177 rubles.

Zosungidwa zamankhwala

Sungani pa kutentha kosaposa 25 ° C kuchokera kwa ana. Kuyimitsidwa kwamaliridwe kumasungidwa pa kutentha kwa +2 mpaka + 8 ° C.

Tsiku lotha ntchito

Alumali moyo wa mankhwala ndi zaka 3. Kuyimitsidwa kwamaliridwe kumasungidwa osaposa sabata limodzi. Osagwiritsa ntchito tsiku lanu litatha.

Wopanga

Mankhwalawa amapangidwa m'maiko osiyanasiyana, kuphatikizapo Russia, USA, Israel, Germany, Austria, Canada, India, Egypt, ndi ena.

Omwe ali ndi magwiridwe ofananawo amaphatikizanso mankhwala a Amosin.

Ospamox imakhudzanso chimodzimodzi ndi Amoxicillin m'thupi.

Flemoxin solutab amatchulidwa pofotokozera monga mankhwala omwe ali ofanana mu thunthu.

Mapangidwe ofanana ndi Hiconcil.

Ngati ndi kotheka, mankhwalawa amatha kutha ndi Ecobol.

Ndemanga

Natalia, wazaka 24, Krasnodar

Adadwala chimfine kuyambira ali mwana. Kubwezerera kumachitika kawiri pachaka. Amoxicillin amathandizira kufika kumapazi anu mwachangu, osanama kwa sabata limodzi.

Maxim, wazaka 41, Ufa

Nthawi zambiri sinditembenukira ku maantibayotiki. Koma ngati ndilandira zinazake kuchokera kuzizira, ndiye Amoxicillin. Ili ndi mphamvu yofatsa, siyotsika mtengo. Kugwiritsa 100%.

Nelly, wazaka 38, Saratov

Mankhwalawa ndi othandizira, koma amatha kuyambitsa mavuto ambiri. Panali vuto la bacteriolysis, kutentha kunakwera, ndimayenera kuyimbira dokotala. Zinthu sizibwerera mwachangu.

Anna, wazaka 31, Samara

Mankhwalawa adathandizira kuchiza pyelonephritis. Ndikupangira.