Insulin Humulin NPH: malangizo, analogues, ndemanga

Limagwirira zake insulin Humulin NPH

Mphamvu ya pharmacological ndi kuchepa kwa shuga m'magazi chifukwa chakuwonjezeka kwa kutengeka kwake ndi maselo ndi minofu yogwiritsira ntchito Humulin NPH. Mu shuga mellitus, kupanga kwa pancreatic insulin timadzi kumachepetsedwa, komwe kumafunikira mankhwala othandizira. Mankhwala amalimbikitsa kugwiritsidwa ntchito kwa glucose ndi maselo omwe amafunikira zakudya. Insulin imalumikizana ndi ma receptors apadera pamaselo a cell, omwe amachititsa kuti pakhale zochitika zingapo, zomwe zimaphatikizapo, makamaka, kupanga hexokinase, pyruvate kinase, ndi glycogen synthetase. Kutumiza kwa glucose kumisempha kuchokera m'magazi kumachuluka, komwe kumakhala kocheperako.

Mankhwala

• Achire zotsatira akuyamba ola limodzi jekeseni.
• Kutsitsa kwa shuga kumatenga pafupifupi maola 18.
• Zotsatira zazikulu zimakhala pambuyo pa maola awiri mpaka maola 8 kuchokera pakukonzekera.

Kusintha kwakanthawi kwamankhwala kumadalira malo omwe amayimitsidwa ndi kuyendetsa galimoto kwa wodwalayo. Izi zimayenera kuganiziridwanso popereka dongosolo komanso kuchuluka kwa makonzedwe. Popeza kutalika kwa zotsatira zake, Humulin NPH imayikidwa pamodzi ndi insulin yochepa komanso ya ultrashort.

Kugawa ndi kutulutsa thupi:

• Insulin Humulin NPH simalowa mu chotchinga cha hematoplacental ndipo samatuluka m'matumbo a mkaka ndi mkaka.
• Inactivine mu chiwindi ndi impso kudzera enzyme insulinase.
• Kuthetsa mankhwalawa makamaka kudzera impso.

Zizindikiro, contraindication ndi mavuto

Humulin NPH adapangidwa kuti azilamulira shuga mwa odwala omwe ali ndi matenda a shuga omwe amadalira insulin, komanso ndi kupezeka koyamba kwa hyperglycemia mwa amayi panthawi yomwe ali ndi pakati.

Zoyipa:

• Hypersensitivity mankhwala ndi zida zake;
• kutsika kwa shuga m'munsi 3.3 - 5.5 mmol / l m'magazi.

Zosafunikira zoyipa zimaphatikizapo:

• hypoglycemia ndimavuto owopsa komanso osakwanira kupanga. Imadziwoneka ngati kutayika kwa chikumbumtima, komwe kumatha kusokonezeka ndi chikomokere;
• mawonetseredwe a thupi lawo m'malo a jakisoni (redness, kuyabwa, kutupa);
• kuthamangitsa;
• kupuma movutikira
• hypotension;
• urticaria;
• tachycardia;
• lipodystrophy - mankhwala a kwawo a subcutaneous mafuta.

Malamulo ogwiritsira ntchito

1. Mankhwalawa amayenera kuperekedwa pansi pa khungu la mapewa, m'chiuno, matako kapena khoma lamkati, ndipo nthawi zina jakisoni wamkati imatheka.
2. Pambuyo pa jekeseni, simuyenera kukanikiza mwamphamvu ndi kutikita minofu kumalo omwe mwalowa.
3. Ndi zoletsedwa kugwiritsa ntchito mankhwalawa.
4. Mlingo umasankhidwa payekha ndi endocrinologist ndipo umatengera zotsatira za kuyezetsa magazi kwa shuga.

Algorithm yoyendetsera insulini ya Humulin NPH

Kukonzekera:

• Humulin mu Mbale iyenera kusakanizika musanagwiritse ntchito ndikulowetsa vial pakati pa kanjedza mpaka khungu la mkaka litawonekera. Osagwedezeka, thovu, kapena kugwiritsa ntchito insulin yotsalira pamakoma a vial.
• Humulin NPH m'matakatoni osangosuntha pakati pa manja, kubwereza kayendedwe ka 10, komanso kusakaniza, modekha ndikusintha cartridge. Onetsetsani kuti insulin ndi yoyenera kuyendetsedwa poyang'anira kusasinthasintha ndi mtundu. Payenera kukhala zofanana pamtundu wa mkaka. Komanso musagwedeze kapena kufumba mankhwala. Osagwiritsa ntchito yankho ndi phala kapena phala. Ma insulini ena sangayikiridwe katiriji ndipo sangathe kudzazidwanso.
• Cholembera cha syringe chili ndi 3 ml ya insulin-isophan pa mlingo wa 100 IU / ml. Pa jakisoni 1, lowetsani osaposa 60 IU. Chipangizocho chimalola kuyimilira metro molondola mpaka 1 IU. Onetsetsani kuti singano ndiyomatirira pachidacho.

- Sambani m'manja pogwiritsa ntchito sopo, kenako muziwathandiza.

- Sankhani malo a jakisoni ndikuwathandiza khungu ndi yankho la antiseptic.

- Masamba obayira enanso kuti malo omwewo sawagwiritsanso ntchito kamodzi pamwezi.

Zomwe zimagwiritsidwa ntchito pa cholembera chida

1. Chotsani kapu poikoka m'malo mozunguliza.
2. Onani insulin, moyo wa alumali, kapangidwe kake ndi mtundu wake.
3. Konzani singano ya syringe monga tafotokozera pamwambapa.
4. Pukuta singano mpaka itakhala yolimba.
5. Chotsani zisoti ziwiri ku singano. Kunja - osataya.
6. Onani kuchuluka kwa insulin.
7. Pindani khungu ndikulowetsa singano pansi pa khungu pakona madigiri 45.
8. Yambitsani insulini pogwira batani ndi chala chanu mpaka chitayima, kuwerengetsa pang'onopang'ono m'maganizo mpaka 5.
9. Mukachotsa singano, ikani nyemba za mowa pamalo a jekeseni osapaka kapena kupwanya khungu. Nthawi zambiri, dontho la insulin limatha kukhalabe kumapeto kwa singano, koma osati kutayikira, zomwe zikutanthauza kuti mlingo wosakwanira.
10. Tsekani singano ndi kapu yakunja ndikuitaya.

Kuyanjana kwina ndi mankhwala ena

Mankhwala omwe amalimbikitsa Humulin:

• zolemba hypoglycemic;
• antidepressants - monoamine oxidase zoletsa;
• hypotonic mankhwala ochokera pagulu la ACE zoletsa ndi beta-blockers;
• kaboni anhydrase zoletsa;
• imidazoles;
• tetracycline mankhwala;
• kukonzekera kwa lithiamu;
• Mavitamini a B;
• theophylline;
• mankhwala okhala ndi zakumwa zoledzeretsa.

Mankhwala omwe amalepheretsa insulin Humulin NPH:

• mapiritsi oteteza kubala;
• glucocorticosteroids;
• mahomoni a chithokomiro;
• okodzetsa;
• ma tridclic antidepressants;
• othandizira omwe amachititsa kuti mitsempha ichite chisoni;
• calcium blockers;
• narcotic analgesics.

Zolemba za Humulin

Ndemanga ya insulin-isophan antidiabetesic mankhwala:

Ndinkafuna kukonza - ndizoletsedwa kupereka insulin nthawi yayitali!

Malangizo apadera ogwiritsa ntchito

Mankhwala ayenera kuperekedwa ndi dokotala. Chokani ku pharmacies ndi mankhwala. Pochita mankhwala ndi Humulin NPH, kuwunika pafupipafupi kuchuluka kwa shuga kumafunika. Pamaso pa matenda ophatikizika - funsani dokotala kuti musinthe mlingo.