Zowonetsa ndi njira yogwiritsira ntchito insulin Glargin

Pochiza matenda a shuga, mitundu yosiyanasiyana ya mankhwala imagwiritsidwa ntchito. Amasiyana pakapangidwe kake ndi kagwiritsidwe ntchito kake.

Anthu ambiri odwala matenda ashuga amafuna insulin kuti ikhale ndi thanzi labwino. Chimodzi mwa mitundu yake yomwe imagwiritsidwa ntchito ngati jakisoni ndi insulin Glargin.

Zambiri

Mankhwala ndi a gulu la insulin. Malonda ake ndi Lantus. Wothandizira amagwiritsidwa ntchito pochiza matenda a shuga a insulin. Imapezeka ngati jakisoni. Madziwo alibe mtundu ndipo ali pafupi kuwonekera.

Insulin Glargin ndi chithunzi cha insulin ya anthu yopangidwa ndi mankhwala. Zovuta pazantchito yayitali. Mankhwalawa amathandizira kuchepetsa kuchuluka kwa shuga m'magazi a wodwala.

Gawo lalikulu la kapangidwe kake ndi Glargin insulin.

Kuphatikiza apo, yankho limaphatikizapo:

• glycerol;
• nthaka ya chloride;
• metacresol;
• hydrochloric acid;
• sodium hydroxide;
• madzi.

Mankhwalawa amaloledwa kugwiritsidwa ntchito pokhapokha ndi chilolezo cha katswiri komanso muyezo womwe wapatsidwa ndi iye, pofuna kupewa zovuta.

Mankhwala

Zotsatira zazikulu za mankhwalawa ndi kuchepa kwa shuga. Izi zimachitika kudzera pakupanga mgwirizano pakati pake ndi insulin receptors. Njira yofananira yomweyo imadziwika ndi insulin ya anthu.

Mothandizidwa ndi mankhwalawa, kagayidwe kazakudya kamapangidwa, chifukwa minofu ya m'mapazi imayamba kudya kwambiri.

Kuphatikiza apo, Glargin amalepheretsa kupanga shuga mu chiwindi. Mothandizidwa ndi iye, njira yopanga mapuloteni imathandizira kwambiri. Njira ya lipolysis, m'malo mwake, imachepetsa.

Pambuyo kulowetsedwa kwa mankhwala kulowa mthupi, sikumatha, microprecipitate imapangidwa. Pulogalamu yogwira imakhazikika mwa iwo, yomwe imamasulidwa pang'onopang'ono. Izi zimathandizira kutalika kwa mankhwalawa komanso kusalala kwake, popanda kusintha kwakukulu.

Zochita za Glargin zimayamba ola limodzi jekeseni. Imapitirira pafupifupi tsiku limodzi.

Zizindikiro, njira ya makonzedwe

Kwa chithandizo chokwanira, malangizo ogwiritsa ntchito mankhwalawa akuyenera kutsatiridwa. Malamulo akuvomerezedwa nthawi zambiri amafotokozedwa ndi adokotala.

Insulin Glargin imayikidwa pokhapokha ngati pali chifukwa. Kugwiritsidwa ntchito kwake ndikofunikira kwa mtundu wodalira inshuwaransi - izi zikutanthauza kuti matendawa ndi omwe amakhazikitsidwa.

Komabe, mankhwalawa ali osavomerezeka kwa aliyense - katswiri ayenera kupenda chithunzithunzi cha matenda nthawi zonse.

Kugwiritsa ntchito kololedwa kwa mitundu yonse yoyamba komanso yachiwiri. Mu mtundu woyamba wa matenda, mankhwalawa amagwiritsidwa ntchito ngati mankhwala akuluakulu. Kwina, Glargin akhoza kutumikiridwa onse mu mawonekedwe a monotherapy komanso kuphatikiza ndi mankhwala ena.

Mlingo nthawi zonse umawerengeredwa payekha. Izi zimakhudzidwa ndi kulemera kwa wodwalayo, zaka zake, koma chofunikira kwambiri ndi mawonekedwe a matendawa. Pa mankhwalawa, kuyezetsa magazi nthawi zina kumachitika kuti mumvetsetse momwe mankhwalawo amagwirira ntchito, ndikuchepetsa kapena kukulitsa nthawi.

Mankhwalawa amagwiritsidwa ntchito ngati ma jakisoni, omwe amayenera kuchitika mosazindikira. Pafupipafupi jakisoni kamodzi patsiku. Malinga ndi malangizo, akuyenera kuzichita nthawi yomweyo - izi zimathandiza kugwiranso ntchito komanso kusapezeka kwa zoyipa. Jakisoni amayikidwa paphewa, ntchafu kapena m'minyewa yamafuta am'mimba. Pofuna kupewa zoyipa, malo ena oyang'anira.

Maphunziro a kanema wa syringe-cholembera insulin

Contraindators ndi malire

Kugwiritsa ntchito kwa mankhwala aliwonse kuyenera kusamala chifukwa chakuti onse ali ndi zotsutsana. Kugwiritsa ntchito mankhwala osasokoneza contraindication ndi zoletsa kungayambitse zovuta.

Mankhwalawa ali ndi zotsutsana zochepa. Izi zimaphatikizapo kusalolera kwamunthu aliyense payekha pazigawozo, chifukwa cha zomwe zimayambitsa thupi.

Mlandu wina pamene kugwiritsidwa ntchito kwa mankhwalawa kutayidwa ndikufika zaka za wodwalayo zosakwana zaka 6. Poyerekeza ndi ana, kugwiritsa ntchito mankhwalawa sikunafufuzidwe, chifukwa chake palibe chidziwitso chokwanira ndikuyenerera kwa kayendetsedwe kake.

Zolephera zake zimaphatikizapo:

1. Zovuta pakugwira ntchito kwa impso. Ndi kuphwanya izi, metabolism ya insulin imatha kuchepetsedwa. Izi zikutanthauza kuti wodwala adzafunika mankhwala ochepa kuti athe kutsata shuga.
2. Ukalamba (woposa zaka 65). Odwala omwe ali ndi zaka zino, ntchito ya ziwalo zamkati, kuphatikizapo impso, imakula. Chifukwa chake, angafunike kuchepa kwamankhwala.

Kulephera kumatanthawuza kuchenjera kwa dokotala popereka mankhwala. Ngati ilipo, mankhwalawa akhoza kuvomerezedwa, koma atatsimikizika.

Mimba komanso kuyamwa

Palibe maphunziro atsatanetsatane omwe adachitika okhudzana ndi kugwiritsa ntchito mankhwala a insulin glargine pa nthawi yobereka. Zotsatira za kuyesa kwina zikuwonetsa kuwonongeka kwakuipa kwa chinthu yogwira pokhudzana ndi msambo komanso kukula kwa fetal.

Chifukwa chake, sikulimbikitsidwa kugwiritsa ntchito chida ichi mankhwalawa amayi apakati. Itha kuthandizidwa ngati phindu la mankhwala kwa mayi ndilokwera kuposa chiwopsezo cha mwana.

Nthawi yomweyo, kuyang'aniridwa mosamala kuchipatala ndikofunikira, chifukwa nthawi yomwe mayi ali woyembekezera, shuga a wodwala amatha kusiyanasiyana kutengera nthawi. Madokotala amayenera kudziwa kuchuluka kwa shuga kuti asinthe mankhwalawa.

Ndi mkaka wa m`mawere, mankhwalawa amadziwikanso ngati pakufunika. Kuchepetsa kwa insulin mkaka wa m'mawere sikunachitike.

Komabe, chinthuchi chimawonedwa ngati chotetezeka, popeza chili ndi puloteni, motero, sichitha kuvulaza mwana wakhanda. Koma mukamagwiritsa ntchito ndi mayi woyamwitsa, muyenera kusankha mlingo woyenera, komanso kutsatira malangizo pazakudya.

Zotsatira zoyipa ndi bongo

Ngakhale mutakufotokozerani mankhwala ndi dokotala, simungakhale otsimikiza kuti kugwiritsa ntchito kwake kudzachita popanda zovuta. Ngakhale kutsatira malangizo, mankhwala nthawi zina amakhala ndi vuto losayembekezereka, lomwe limalumikizidwa ndi machitidwe a thupi. Chifukwa chake, zoyipa zimachitika.

Mukamagwiritsa ntchito mankhwalawa, zovuta zimatha kukhalapo monga:

1. Hypoglycemia. Izi zimachitika ndi insulin yambiri mthupi. Nthawi zambiri, mawonekedwe ake amaphatikizidwa ndi mlingo wosankhidwa wa mankhwalawa, koma nthawi zina zifukwa zake zimachokera mthupi. Kuphwanya malamulo otere ndi koopsa, chifukwa kumakhudza kugwira ntchito kwamanjenje. Ndi hypoglycemia yayikulu komanso kusowa kwa thandizo, wodwala amatha kufa. Kupatuka uku kumadziwika ndi zizindikiro monga kutayika kwa chikumbumtima, palpitations, kukokana, komanso chizungulire.
2. Zowonongeka. Ndi mankhwala a insulin, kuchuluka kwina kwa glucose nthawi zina kumawonedwa, komwe kungayambitse retinopathy. Wodwalayo mwina sanathe kuwona, mpaka khungu.
3. Lipodystrophy. Otchedwa kuphwanya pokonza mankhwala. Izi zitha kupewedwa mothandizidwa ndi kusintha kosalekeza kwa malo a jakisoni.
4. Ziwengo. Ngati kuyesedwa koyenera kwa chidwi ndi mankhwalawa kunachitika musanagwiritse ntchito Glargin, zotere zimachitika kawirikawiri ndipo sizimasiyana pakukwiya. Kuwonetsera kwina kwambiri pamenepa: zotupa pakhungu, redness pakhungu ndi kuyabwa pamalo a jekeseni.

Ngati mungapeze zotere, mosasamala kanthu za kulimba kwake, muyenera kufunsa dokotala. Nthawi zina, mutha kuwachotsa posintha mankhwalawa. Ndipo nthawi zina kusintha msanga kwa mankhwala kumafunika.

Kutsatira malangizo a dokotala kumapewetsa mavuto omwe amabwera chifukwa cha mankhwala osokoneza bongo. Koma nthawi zina izi sizithandiza. Vuto la mankhwala osokoneza bongo, hypoglycemia nthawi zambiri limachitika. Kuchotsa kwake kumadalira kukula kwa chizindikirocho. Nthawi zina mutha kuyimitsa chiwopsezocho pomamwa chakudya chamafuta othamanga. Ndi chiwopsezo chachikulu, thandizo la dokotala ndilofunikira.

Kuchita ndi zinthu zina, analogi

Munthu akakhala ndi matenda ena kupatula matenda a shuga, pamakhala kufunikira kwamankhwala osiyanasiyana munthawi yomweyo. Kuphatikiza koteroko sikumakhala kotetezeka nthawi zonse - ichi ndi chifukwa chake sikulimbikitsidwa kudzilimbitsa.

Mukamamwa inshuwaransi ya Glargin, kusamala ndikofunikanso, chifukwa kugwiritsa ntchito nthawi yomweyo ndi mankhwala ena kungayambitse zovuta. Chifukwa chake, adotolo ayenera kudziwa zamankhwala onse omwe wodwala amagwiritsa ntchito.

Choopsa ndichakuti kumwa mankhwala ena kumatha kuwonjezera mphamvu ya mahomoni. Izi zimayambitsa kuwonjezeka kwa thupi ndikupanga chiopsezo cha hypoglycemia.

Mankhwalawa ndi monga:

• othandizira a hypoglycemic;
• ATP zoletsa;
• salicylates;
• mafupa;
• antimicrobial othandizira a sulfanilamide chiyambi;
• monoamine oxidase zoletsa.

Kugwiritsa ntchito mankhwalawa nthawi imodzi ndi insulin Glargin ndikuloledwa, koma ndikofunikira kuchepetsa kuchuluka kwa zinthu zomwe zimayendetsedwa.

Pogwiritsa ntchito mankhwala ena, kufooka kwa mphamvu ya mankhwalawa kuonedwa. Zotsatira zake ndi kuchepa kwa kuwongolera kwa glucose.

Ena mwa mankhwalawa ndi:

• estrogens;
• okodzetsa;
• glucocorticosteroids;
• antipsychotic (ena);
• mahomoni a chithokomiro.

Ngati mankhwalawa sangathe kutha, ndiye kuti muthandizike pamafunika kuonjezera mlingo wa Insulin glargine.

Zowopsa kwambiri ndikuphatikizana komwe kumapangitsa kuti thupi lizigwirizana. Mukamagwiritsa ntchito mankhwalawa limodzi ndi beta-blockers, Pentamidine, Clonidine kapena mowa, zotsatira zake zingathe kufooka ndikukula. Chifukwa chake, chisamaliro chapadera chimafunika ndi mankhwalawa komanso zinthu zina.

Zofanana poyerekeza ndi insulin Lantus ndi Levemir:

Nthawi zina zimakhala zofunikira kusintha Glargin ndi mankhwala ena. Nthawi zambiri chifukwa cha izi ndi tsankho la mankhwalawa, koma mtengo wa mankhwalawo umawonedwanso ngati chinthu china chofunikira.

Mutha kusintha m'malo mwake ndi mankhwala osangalatsa monga Lantus (mtengo kuchokera ku 690.00 rubles), Lantus SoloStar (kuchokera ma ruble 690.00), Tujeo SoloStar (kuchokera ma ruble 951.00)

Dokotala amayenera kumwa mankhwalawo ndi analogi yake atamaliza kuyesa. Kuchita izi nokha sikuletsedwa.