Mwa mankhwala omwe amagwiritsidwa ntchito pochiza matenda a shuga, titha kutchula yankho la Yanumet.
Nthawi zambiri amalembedwa kwa odwala matenda ashuga, ndipo ndikofunikira kudziwa momwe mankhwalawa alili odabwitsa komanso momwe angagwiritsire ntchito. Mu radar, chida ichi chimagawidwa ngati hypoglycemic. Kutulutsidwa kwake kumakhazikitsidwa ku Netherlands.
Yanumet ndi mankhwala omwe mumalandira, popeza kuikidwa ndi dokotala ndikofunikira kuti mutenge. Popanda ichi, simuyenera kugwiritsa ntchito chida ichi kuti mavuto asatuluke. Ngati muli ndi mankhwala, muyenera kutsatira malangizowo, chifukwa pali zoopsa zambiri zoyipa.
Kuphatikizika, mawonekedwe omasulidwa
Mankhwalawa amagulitsidwa m'mapiritsi okhala ndi ntchito. Zimakhazikitsidwa pazinthu 2 zogwira ntchito, chifukwa chomwe zotsatira zake zimapezeka - Metformin ndi Sitagliptin.
Kuonjezera phindu la mankhwalawa, zinthu zothandizira zotsatirazi zidawonjezeredwa pazomwe zimapangidwa:
- talc;
- macrogol;
- ma cellcose a microcrystalline;
- sodium stearyl fumarate;
- povidone;
- titanium dioxide;
- sodium lauryl sulfate;
- mowa wa polyvinyl.
Mapiritsi a Yanumet ndi amitundu itatu, kutengera zomwe zili mu Metformin (500, 850 ndi 1000 mg).
Sitagliptin m'magulu onsewa imakhala yofanana - 50 mg. Utoto wa mapiritsiwo ukhoza kukhala wopinki, wapinki komanso wofiyira.
Mankhwalawa amadzaza matuza a ma PC 14. Mapaketi amatha kukhala ndi matuza osiyanasiyana.
Kanema wokhudza katundu wa Metformin:
Pharmacology ndi pharmacokinetics
Chidacho chili ndi tanthauzo lotchedwa hypoglycemic, lomwe limachitika chifukwa chogwirana ndi magawo awiri ogwira ntchito. Chifukwa cha sitagliptin, kuchuluka kwa insulin yopanga ma cell a beta kumachuluka. Komanso, mankhwalawa amachepetsa kapangidwe ka shuga m'chiwindi.
Chifukwa cha Metformin, chiwopsezo cha thupi cha insulin chimakulitsidwa ndipo njira yolembera shuga m'magawo am'mimba imachepa. Izi zimapereka zovuta ku thupi chifukwa cha zomwe glucose imakhala yofanana. Nthawi yomweyo, Yanumet samayambitsa hypoglycemia (kupatula milandu ngati wodwala matenda ashuga ali ndi matenda osokonekera amachititsa mankhwala.
Sitagliptin
Kuyamwa kwa sitagliptin kumachitika mwachangu kwambiri. Kuchuluka kwa zinthu izi (komanso mphamvu yayikulu) zimawonedwa munthawi ya maola 1-4 mutamwa mankhwalawa.
Nambala yochepa chabe yomwe imalowa mu mapuloteni a plasma.
Chigawocho sichimapanga metabolites ndipo pafupifupi chimatulutsidwa kudzera mu impso momwe kale. Zina zonse zimathetsedwa ndi ndowe.
Mayamwidwe a Metformin amadziwikanso ndi kuthamanga kwambiri. Zotsatira zake zimafika pazokwera pambuyo pa maola awiri. Sipangokhala ngati ma protein a plasma. Kupatula kwa chinthuchi kumachitika ndi impso.
Zizindikiro ndi contraindication
Kugwiritsa ntchito mankhwalawa kumaloledwa pokhapokha ngati mukuyenera kuzindikira. Ngati sichoncho, mankhwalawo amangovulaza munthuyo. Chifukwa chake, ndikofunikira kuti Yanumet asankhe katswiri. Izi zimachitika kwa matenda ashuga amtundu wa 2.
Chithandizo chake amachitidwa m'njira zingapo. Nthawi zina amagwiritsidwa ntchito mankhwalawa (kuphatikizapo chakudya). Ndizothekanso kugwiritsa ntchito mapiritsi awa ndi mankhwala ena (mwachitsanzo, ndi insulin kapena zotumphukira za sulfonylurea). Kusankhako kumachitika chifukwa cha chithunzi cha matenda.
Popanda kuikidwa ndi dokotala, mankhwalawa saloledwa kugwiritsidwa ntchito chifukwa cha contraindication. Kukhalapo kwawo kungapangitse kukulira kwa mavuto omwe alipo.
Contraindations akuphatikiza:
- tsankho kwa zosakaniza;
- matenda oopsa a impso;
- kuphwanya kwambiri chiwindi;
- matenda opatsirana;
- zakumwa zoledzeretsa kapena zakumwa zoledzeretsa;
- ketoacidosis;
- mtundu 1 shuga;
- myocardial infarction;
- kulephera kwa mtima;
- mimba
- kudya kwachilengedwe.
Izi zimafuna kusiyidwa kwa ntchito kwa Yanumet, ngakhale kukhalapo koyenera koyenera. Dokotala ayenera kusankha njira ina yothandizira kuti asawononge moyo wa wodwalayo.
Malangizo ogwiritsira ntchito
Kuti mankhwalawa asavulaze wodwala, kutsatira malangizo ndikofunikira. Ndikofunika kudziwa za malamulo ovomerezeka ndi dokotala, chifukwa nthawi ndi mitundu ingathe kusiyanasiyana kutengera ndi matendawa.
Katswiriyo ayenera kudziwa wodwalayo ndi kudziwa kuchuluka kwa mankhwalawo omwe ali oyenera kwa iye.
Ndikofunikira ngakhale pang'ono kuti muchepetse kumayambiriro kwa mankhwala. Chifukwa chake thupi lidzatha kuzolowera kulandirira ndalama. M'tsogolomu, mlingo umatha kuwonjezereka ngati zotsatira za kuyezetsa magazi zikuwonetsa kufunikira kwa izi.
Muyenera kuyang'ana kuchuluka kwa sitagliptin. Mlingo wovomerezeka wa chinthu ichi ndi 100 mg patsiku. Mlingo wa Metformin ukhoza kukhala wosiyanasiyana. Mankhwalawa amatengedwa kawiri patsiku ndi zakudya. Pukuta mapiritsi safuna.
Odwala apadera
Contraindication sichiri chifukwa chokhacho chomwe chisamaliro chimafunikira pakugwiritsa ntchito mankhwalawa. Njira zapadera zimaperekedwa kwa wodwala payekhapayekha, chifukwa anthu awa amatha kudziwika ndi chidwi chochulukirapo pazovuta za zida.
Izi zikuphatikiza:
- Amayi oyembekezera. Kwa iwo, kutenga Yanumet ndikosayenera, popeza sizikudziwika momwe mankhwalawa angakhudzire mayendedwe apakati komanso kukula kwa mwana. Komabe, ngati pakufunika thandizo la mankhwalawa ndi mankhwalawa, adotolo akhoza kuupereka.
- Amayi oyamwitsa. Zotsatira za zinthu zomwe zimagwira pa mkaka sizinaphunzire. Pankhani imeneyi, pakubala, munthu ayenera kupewa kumwa mankhwalawa pofuna kupewa kuvulaza mwana. Ngati chithandizo ndi Yanumet chikufunikirabe, siyani kuyamwitsa.
- Anthu okalamba. Amatha kukumana ndi zovuta zingapo pakugwira ntchito kwa thupili chifukwa cha kusinthana ndi ukalamba. Komanso, pamene wamkulu ali ndi zaka zodwala, ndiye kuti zambiri zimayambitsa kuphwanya malamulo kotere. Chifukwa cha izi, zimakhala zovuta kutengera mankhwala ndikuchotsa mankhwalawa. Chifukwa chake, kwa odwala otere, ndikofunikira kusankha mosamala mlingo. Komanso, ayenera kuwunika chiwindi ndi impso pafupifupi kamodzi miyezi isanu ndi umodzi kuti azindikire zovuta zomwe zili mderali.
- Ana ndi achinyamata. Chifukwa cha kuchepa mphamvu kwa thupi la odwala otere, Janumet angawakhudze mosakonzekera. Madokotala amapewa kulandira mankhwalawa pakadali pano, amakonda mankhwala ena.
Ngati matenda a shuga akupezeka mwa oyimira m'maguluwa, akatswiri ayenera kuchita zinthu mosamala ndikutsatira malangizowo.
Malangizo apadera
Kukhalapo kwa matenda oyanjananso ndimwambo wofunsidwa bwino asanakwane Yanumet.
Izi ndizofunikira makamaka pazochitika zotsatirazi:
- Matenda a impso. Ndi kuphwanya kochepa mu ntchito ya thupi, mankhwala amaloledwa. Mikhalidwe yochepa kapena yoopsa imatanthawuza kusiyidwa kwa kugwiritsidwa ntchito kwake, chifukwa chifukwa cha iwo, mawonekedwe a zinthu zomwe zimagwira m'thupi azitha kuchepa, zomwe zingayambitse hypoglycemia.
- Kupatuka pakugwira ntchito kwa chiwindi. Mankhwalawa amakhudza chiwindi. Ngati pali zovuta ndi chiwalochi, izi zimatha kukula, zomwe zimabweretsa zovuta. Chifukwa chake, ndizoletsedwa kutenga Yanumet pankhaniyi.
Chipangizocho chiribe mphamvu yakuwongolera kuthamanga ndi chidwi, kotero kuyendetsa ndi ntchito zomwe zimafunikira kuti zitsimikizidwe sizoletsedwa. Koma mukamagwiritsa ntchito mankhwalawa limodzi ndi othandizira ena, mungayambitse vuto la hypoglycemic, chifukwa cha zovuta zomwe zingachitike m'derali.
Zotsatira zoyipa ndi bongo
Kugwiritsa ntchito mankhwalawa kungayambitse kukulitsa mavuto.
Zina mwa izo ndi:
- kutsokomola
- mutu
- kupweteka kwam'mimba
- nseru
- kugona
- matenda am'mimba thirakiti;
- kapamba
Izi sizimachitika nthawi zonse, ndipo kupezeka kwawo nthawi zambiri sikuwoneka ngati kowopsa. Nthawi zambiri mawonetseredwe awa amachotsedwa pakapita kanthawi. Izi ndichifukwa chosinthira thupi ndi mankhwalawa. Koma ndi kukula kwakukulu kwa zomwe zalembedwazo, ndikofunikira kuti m'malo mwa Yanumet mukhale njira ina.
Pakakhala mankhwala osokoneza bongo, zomwe zimachitika zimagwirizana ndi mavuto, ndizokhazo zomwe zimatchulidwa. Amatha kuchotsedwa ndikuchotsa zotsalira za mankhwalawa m'thupi ndi hemodialysis. Thandizo lothandiziranso lingakhale lofunikira.
Kuyanjana Ndi Mankhwala Ndi Analogi
Matenda opatsirana amafunika kuwongolera njira yosankhidwa ya mankhwala. Ngati akupezeka, ndikofunikira kuthana ndi ma pathologies angapo nthawi imodzi, motero, pakufunika kuphatikiza kwa mankhwala osiyanasiyana.
Kafukufuku atsatanetsatane amomwe zotsatira za Yanumet pamankhwala ena sanachitidwire. Koma ndikudziwika kuti imatha kusintha kusintha kwa mankhwala ena mukamagwiritsa ntchito limodzi.
Zina mwa izo ndi:
- Furosemide;
- Nifedipine;
- Digoxin;
- Cyclosporin;
- Januvius.
Ngati pakufunika kugwiritsa ntchito zinthu zoterezi, muyenera kusankha mosamala mankhwalawa ndikuwunika njira yochiritsira.
Mankhwalawa amadziwika kuti ndi othandizira pochiza matenda ashuga, koma siabwino kwa onse odwala. Chifukwa cha izi, zimakhala zofunikira kusankha ndalama zomwe zikufanana.
Zina mwazofanana ndi Yanumet zomwe zimapezeka ku Russia ndi izi:
- Velmetia;
- Tripride;
- Glibomet;
- Avandamet;
- Douglimax, etc.
Kusankha kwa analogi kuyenera kuperekedwa kwa adokotala, popeza kusintha kwa mankhwala kupita kwina kuyenera kuchitika molingana ndi malamulo. Kuphatikiza apo, mankhwalawa omwe ali ndi mndandanda ali ndi contraindication, kulembetsa kwake komwe kumakhala kovomerezeka.
Maganizo a madotolo ndi odwala
Malingaliro a akatswiri pankhani ya Yanumet ndi osiyana kwambiri - si madokotala onse omwe amapereka mankhwala chifukwa cha zovuta zake, odwala amachitanso mosiyanasiyana - wina adathandizira mankhwalawa, ndipo wina adazunzidwa chifukwa cha zovuta. Mtengo wokwera wa mankhwalawo umadziwikanso.
Ndimapereka mankhwala Janumet kwa odwala nthawi zambiri. Imakhala ndi zotsatira zabwino pamavuto ochepa. Koma musanapereke mankhwala, ndikofunikira kuti muwunike wodwalayo kuti awone ngati palibe zotsutsana, mwinanso wodwalayo akuipiraipira.
Maxim Leonidovich, endocrinologist
Zochita zanga, Yanumet sindiye mankhwala otchuka kwambiri. Kuchita kwake kumadalira momwe wodwalayo alili. Ngati pali contraindication, ndizowopsa kupereka. Komanso, sioyenera milandu yonse. Chifukwa chake, ndiyenera kuvomereza kuti nthawi zambiri - odwala amafunika mankhwala ena. Nthawi zina odwala amakana chifukwa cha mtengo wokwera. Ngakhale anzanga ambiri amalabadira mankhwalawa motsimikiza.
Tamara Alexandrovna, endocrinologist
Abambo anga amatenga Yanumet, ndipo akhala akuchita izi kwa chaka chimodzi ndi theka. Alibe zodandaula, kuchuluka kwa shuga kumakhala kwabwinobwino nthawi zonse, mavuto amakumana ndi kuphwanya zakudya.
Marina, wa zaka 32
Mankhwalawa ndiokwera mtengo kwambiri, koma ndikuyenera kutero. Ndinapezeka kuti ndili ndi matenda ashuga zaka 5 zapitazo, choncho ndinayesa mankhwala ambiri. Ena okha ndi omwe sanathandize, pomwe ena adabweretsa zotsatirapo zoyipa. Yanumet ndi mankhwala oyamba omwe sanayambitse zotsatira zoyipa komanso shuga.
Pavel, wazaka 49
Sindingathe kutcha Yanumet ngati mankhwala abwino - sanandithandizire. Poyamba shuga sanachepe, ndiye mwadzidzidzi adagwa kwambiri - adotowo adaganiza kuti ndachulukitsa mlingo. Kwa milungu ingapo ndinali kumwa, ndipo zizindikirazo zinali zabwinobwino, koma ndinali kuzunzidwa ndimutu, ndinayamba kugona osagona bwino, ndipo nthawi zonse ndinali ndi ludzu. Ndiponso, kuchepa kwakachepa kopanda kusintha kwa mlingo. Mavuto ena, chifukwa chake ndidapempha adotolo kuti asinthanenso ndi china chake komanso chotsika mtengo.
Elena, wazaka 42
Mtengo wa mankhwalawa ndi chinthu chofunikira kwambiri chomwe chimakhudza kusankha njira ya mankhwala. Yanumet ali m'gulu la mankhwalawa omwe ali ndi mtengo wokwera - si wodwala aliyense amene angathe kugula. Mtengo wa mankhwalawa umatha kusiyanasiyana malinga ndi kuchuluka komanso kuchuluka kwa mapiritsi omwe ali phukusi.
Mapiritsi a 56 okhala ndi Metformin 1000 mg, muyenera kugwiritsa ntchito ma ruble 2800-3000. Nambala yofanana ya zidutswa pamlingo wa 500 kapena 850 mg umawononga 2700-2900 rubles.
