Biosulin ndi insulin yosungunuka ya genetic engineering synthesis. Amagwiritsidwa ntchito pochiza matenda ashuga - omwe amadalira insulin komanso osadalira insulini. Kutanthauza zakufupikitsa ndi kwapakatikati kuchitapo kanthu.
Dzinalo Losayenerana
Dzinalo losavomerezeka mu Chilatini ndi Biosulin.
Biosulin ndi insulin yosungunuka ya genetic engineering synthesis.
ATX
Khodi yamankhwala ya ATX ndi A10AB01
Kutulutsa mafomu ndi kapangidwe kake
Biosulin P yomwe imayamba mwachangu ntchito yake imapangidwa mwanjira yothetsera jakisoni. 1 cm³ imakhala ndi 100 IU ml ya insulini yopangidwa pogwiritsa ntchito matekinoloje obadwa nawo. Kuphatikiza apo, mapangidwe ake a mankhwalawa amaphatikizapo glycerin, metacresol ndi madzi apadera a jekeseni. Ampoules ali mu paketi ya ma contour osiyanasiyana.
Kuyimitsidwa
Biosulin H nthawi yayitali imapangidwa mwanjira yoyimitsa jakisoni pansi pa khungu. Ndi yoyera, yoyika pang'ono nthawi yosungirako. Imabwezeretsedwa mosavuta pakamagwedezeka.
Zotsatira za pharmacological
Timadzi timene timagwira ndi ma insulin receptors a cell, chifukwa chomwe kukonzanso kwa glucose amachitika. Ndondomeko ya mayamwidwe ake ndi minofu yamatumbo imayendetsedwa, mapangidwe a glycogen amachitidwa, ndipo kupanga shuga m'magazi a chiwindi kumachepetsedwa.
Kukhazikika kwa ntchito yochita pakati pa Biosulin kuyambira 1 mpaka 2 maola. Zotsatira zazikulu zimachitika pambuyo pa maola 6-12, ndipo kutalika kwa zochitika kumafika mpaka maola 24.
Timadzi timene timagwira ndi ma insulin receptors a cell, chifukwa chomwe kukonzanso kwa glucose amachitika.
Kukhazikika kwa hypoglycemic zochita za Biosulin mwachidule kuli pafupifupi mphindi 30. Chochulukitsa chachikulu pambuyo poti jakisoni wasungidwa mu maola 2-4, nthawi yayitali yochita ndi maola 6-8.
Pharmacokinetics
Biosulin H wa sing'anga yayitali nthawi yochitikira amadzipereka kumalo opukusira. Imagawidwa mthupi mosiyanasiyana. Kupyola chotchinga, placenta sichilowa, sichidutsa mkaka wa m'mawere. Imayamba kuwonongeka m'ziwindi za chiwindi. Ambiri mwa mankhwalawa amachotsedwa m'thupi ndi impso.
Mwachidule kapena kutalika
Chipangizocho chili ndi nthawi yayifupi komanso yapakati. Cholinga chake chimatengera mtundu wa matenda aanthu.
Zizindikiro zogwiritsidwa ntchito
Biosulin H akuwonetsedwa kuti agwiritsidwe ntchito kuzindikira matenda a shuga 1. Mtundu wachiwiri, amawerengedwa kwa odwala chifukwa chokana mankhwala osokoneza bongo omwe amachepetsa shuga.
Biosulin H akuwonetsedwa kuti agwiritsidwe ntchito kuzindikira matenda a shuga 1.
Contraindication
Mankhwalawa amaletsedwa mosamala pachiwopsezo cha hypoglycemia komanso chidwi kwambiri ndi insulin.
Ndi chisamaliro
Kusamala kumafunikira kuyika mahomoni a hepatological and nephrological pathologies.
Kodi atenge biosulin?
Lowani pansi pa khungu lakukhuthala, mu minofu kapena mtsempha mphindi 30 musanadye chakudya kapena chakudya pang'ono.
Ndi matenda ashuga
Mlingo wa tsiku ndi tsiku wa mankhwala umatsimikiziridwa kutengera mawonekedwe a wodwalayo. Ndikofunikira kuwerengetsa moyenera kuchuluka kwa insulin yakulemera kwa thupi. Mlingo wamba wa mankhwalawa patsiku amachokera ku 0,5 mpaka 1 IU, kutengera thupi la munthu. Insulin yokonzekera makonzedwe iyenera kukhala kutentha kwambiri. Nthawi zambiri, imayendetsedwa katatu patsiku, ndipo nthawi zina zochulukirapo. Ngati kuchuluka kwa tsiku ndi tsiku kupitilira 0,6 IU / kg, ndiye kuti muyenera kuchita jakisoni 2 m'mbali iliyonse ya thupi.
Mlingo wa tsiku ndi tsiku wa mankhwala umatsimikiziridwa kutengera mawonekedwe a wodwalayo.
Biosulin imalowetsedwa m'mimba, ntchafu, matako, minofu yolimba - paliponse pomwe pali mafuta okwanira. Masamba a jakisoni amasinthidwa kuti ateteze kukula kwa njira ya lipodystrophy.
Intramuscularly kutumikiridwa kokha moyang'aniridwa ndi katswiri. Nthawi zina amaphatikizidwa ndi insulin yapakatikati ya dzina lomweli. Kuyambitsa koteroko kumafunikira kuwunikira pafupipafupi kuchuluka kwa glycemia.
Njira yothandizira ma Biosulin imasiyana malinga ndi mtundu wa mankhwalawa omwe amagwiritsidwa ntchito. Mukamagwiritsa ntchito mtundu umodzi wokha wa insulini, matchulidwe ake amachitika motere:
- Kuwonongeka kwa nembanemba pa botolo ndi ethanol kumachitika.
- Lowetsani mpweya mu syringe muyezo wofanana ndi mlingo womwe wapatsidwa, ndikudzaza botolo ndi mpweya wofanana.
- Mutembenuzire pansi ndi kuyimba muyeso wa Biosulin kale.
- Chotsani singano, chotsani mpweya ku syringe. Onetsetsani kuti kuyimba ndi kolondola.
- Pangani jakisoni.
Mukamagwiritsa ntchito mitundu iwiri yamankhwala, wodwala azichita motere:
- Kuwonongeka kwa utoto womwe uli pamabotolowo kumachitika.
- Muyenera kusunthira botolo ndi insulin yayitali mpaka yankho lake likhale ndi mtundu wofanana (osati loyera).
- Jambulani mpweya mu syringe molingana ndi kuchuluka kwa insulini yapakatikati kapena yayitali. Singano imayikidwa mu beseni ndi insulin, ndikutulutsa mpweya ndikutulutsa singano. Pakadali pano, insulini yapakatikati kapena yayitali simalowa syringe.
- Tengani mpweya mu syringe momwe mungapangire insulin yayifupi. Tulutsani mpweya mu botolo ili. Tembenuzani ndi kujambula kuchuluka kwamankhwala.
- Tulutsani singano, chotsani mpweya wambiri. Chongani mlingo woyenera.
- Bwerezani zomwezo, mutenge insulini yapakatikati kapena yayitali kuchokera ku vial. Chotsani mpweya.
- Pangani jakisoni kuchokera ku zosakaniza za insulin.
Pambuyo pa jekeseni, siyani singano pansi pa khungu pafupifupi masekondi 6.
Chidacho chimatha kupangidwa mu cartridge yomwe ili ndi cholembera cha syringe ndi singano, 5 ml. Cholembera chimayikidwa 3 ml ya insulin. Musanagwiritse ntchito, onetsetsani kuti ndi lopanda chilema. Kathumba katayikidwa mu syringe, Mzere uyenera kuwonekera kudzera pazenera lake la wogwirizira.
Pambuyo pa jekeseni, siyani singano pansi pa khungu pafupifupi masekondi 6. Nthawi yonseyi batani limasungidwa momwe adalowetsera, kotero kulondola kwa mlingo kumatsimikiziridwa. Pambuyo pa nthawi iyi, chogwiriracho chimatha kuchotsedwa mosamala. Katiriji sikuti adapangidwira kuti mupangidwenso;
Mapeto a insulin atatha, ayenera kutayidwa.
Zotsatira zoyipa za biosulin
Mankhwala ochepetsa nthawi yayitali komanso yapakati amakhala ndi zovuta zosagwirizana ndi kagayidwe kazachilengedwe komanso kukhudzidwa kwambiri.
Kuchokera kumbali ya kagayidwe
Zimatha kuyambitsa hypoglycemic. Munthu atha kuona zotsatirazi:
- kutsekeka kwa khungu ndi mucous nembanemba;
- kutuluka thukuta kwambiri
- kumverera kwa palpitations pafupipafupi;
- minofu ikunjenjemera;
- kumva lakuthwa kwanjala;
- chisangalalo chakuthwa, nthawi zina kupsa mtima, mkwiyo, kusokonekera ndi chisokonezo chamalingaliro;
- malungo
- kupweteka m'mutu;
- kuphwanya kwamitsempha.
Hypoglycemia yodalitsika kwa nthawi yayitali ingayambitse vuto la hypoglycemic:
- kutsekeka ndi chinyezi cha khungu;
- kuchuluka kwa mtima;
- chinyezi cha lilime;
- kuchuluka kwa kamvekedwe ka minofu;
- kupuma kosakhazikika komanso kupumira mwachangu.
Wakupweteka kwambiri, wodwalayo sakomoka. Alibe chidwi, minyewa imachepa, thukuta limaleka, mtima wake ukukhumudwa. Kulephera kupuma. Vuto lowopsa kwambiri la hypoglycemic coma ndi matenda am'mitsempha, omwe amatsogolera pakupuma.
Ndikapangidwe kazizindikirozi, ndikofunikira kupatsa munthuyo chithandizo chofunikira munthawi yake. Mwapang'onopang'ono kuperekedwa, munthu sangathenso kukhala ndi vuto loopsa la matenda oopsa. Kukhazikitsidwa kwa insulin mdziko la kuchepa kwa shuga m'magazi kumakhala ndi zotsatira zoyipa za odwala matenda ashuga.
Hypoglycemia yemwe amakhala atasungidwa nthawi yayitali kumatha kupangitsa kuti akomoke.
Matupi omaliza
Ndi jakisoni maphunziro a Biosulin mankhwala, matupi awo sagwirizana: zotupa khungu, edema, zosowa - anaphylactoid zimachitika. Zomwe zimachitika m'deralo pobayidwa jakisoni amatha - kuyabwa, redness, ndi kutupa pang'ono.
Zokhudza mphamvu pakuwongolera njira
Poikapo koyamba kantchitoyo, kusintha ndi kupsinjika, kuthekera kuyendetsa galimoto ndi kugwira ntchito ndi zida zovuta kumatha kusokonezeka. Muzochitika izi, sizikulimbikitsidwa kuchita zochitika zomwe zimafunikira chidwi chochulukirapo komanso kuchitapo kanthu mwachangu kuchokera kwa munthu.
Malangizo apadera
Ndi koletsedwa kugwiritsa ntchito mankhwalawo ngati asintha mtundu kapena tinthu tating'onoting'ono taoneka. Pa mankhwala, muyenera kuwona kuchuluka kwa glucose m'magazi. Zomwe zimawoneka ngati hypoglycemia ndi:
- kulowa kwa insulin;
- kukakamizidwa kufa ndi njala;
- kuchuluka kwakuthwa kolimbitsa thupi;
- matenda omwe amachepetsa kufunika kwa insulini (mwachitsanzo, kukanika kwa impso ndi chiwindi, kuchepa kwa adrenal ntchito, chithokomiro cha chithokomiro kapena gland pituitary);
- kusintha kwa jekeseni;
- mogwirizana ndi mankhwala ena.
Kuphwanya jekeseni wa biosulin mwa odwala matenda a shuga omwe amadalira insulin kumabweretsa kukula kwa hyperglycemia. Mawonekedwe ake:
- kamwa yowuma
- kukodza pafupipafupi;
- kusanza ndi kusanza;
- redness la pakhungu ndi mucous nembanemba;
- kuchepa kwa chakudya;
- kununkhira kwa ma acetone ndi maapulo akhathamira mumlengalenga.
Hyperglycemia yamtunduwu wa shuga popanda chithandizo chokwanira imatha kubweretsa ketoacidosis.
Kusintha kwa mlingo wa Biosulin kumachitika ndi:
- kuchuluka kwa katundu;
- matenda opatsirana;
- Matenda a Addison;
- kuphwanya kwa pituitary gland;
- matenda a chiwindi;
- kusintha kwa zakudya.
Sizoletsedwa kubaya insulini ya nthawi yayitali pakuyimitsidwa ngati, chifukwa cha kukwiya, chimayera ndipo ndi opaque. Homoni wotereyu ndi woipa ndipo amatha kuyambitsa poizoni. Kugwiritsa ntchito mankhwalawa kumapampu a insulin sikuchitika.
Gwiritsani ntchito panthawi yoyembekezera komanso mkaka wa m`mawere
Palibe umboni wa kugwiritsidwa ntchito kwa Biosulin panthawi ya kuyamwitsa ndi bere.
Kupangira Biosulin kwa ana
Mankhwalawa amatha kugwiritsidwa ntchito pochiza ana. Mlingo ndi Mlingo wa mankhwala atsimikiza mtima kumaganizira chikhalidwe cha matenda ashuga.
Gwiritsani ntchito mu ukalamba
Pamafunika kusintha kosiyanasiyana kwa anthu opitilira 65
Mankhwala osokoneza bongo a Biosulin
Ngati mulingo wambiri, hypoglycemia imatha kuchitika. Kuperewera kwa glucose ofatsa kumachotsedwa ndikugwiritsa ntchito shuga kapena zakudya zophatikiza ndi zakudya. Anthu omwe ali ndi matenda ashuga amafunika kukhala ndi maswiti kapena zakudya zilizonse zopatsa mphamvu zamagetsi nthawi zonse.
Amafuna kusintha kwamankhwala mwa anthu opitirira zaka 65.
Ndi chikomokere, Dextrose amalowetsedwa m'mitsempha, glucagon s / c, kulowa mu mtsempha kapena minofu. Wodwalayo akangochira, ayenera kudya zakudya zamafuta a shuga.
Kuchita ndi mankhwala ena
Pali mankhwala omwe amakhudza kufunika kwa odwala matenda ashuga a insulin. Kutsitsa kwa shuga kwa mankhwalawa kumatheka:
- mankhwala ochepetsa shuga ogwiritsira ntchito shuga mkati;
- Mao oletsa mankhwala;
- β-blockers;
- zinthu zomwe zimaletsa ACE;
- sulfonamides;
- ma steroid ndi anabolics;
- kaboni anhydrase ntchito zoletsa;
- Bromocriptine;
- Pyridoxine;
- Octreotide;
- Ketoconazole;
- Mebendazole;
- Theophylline;
- Tetracycline;
- othandizira okhala ndi ma lithiamu;
- mankhwala onse okhala ndi ethyl mowa.
Zotsatira zotsatirazi zimachepetsa ntchito ya Biogulin:
- mankhwala oletsa kubereka mkati;
- GCS;
- zotupa za chithokomiro;
- okodzetsa a mndandanda wa thiazide;
- Heparin;
- antidepressantant;
- othandizira achifundo;
- Clonidine hydrochloride;
- othandizira omwe amaletsa ntchito ya calcium tubules;
- Morphine;
- Phenytoin.
Kusuta kumathandizira kuchepetsa hypoglycemic zotsatira za Biosulin.
Kuyenderana ndi mowa
Imachepetsa kukana kwa thupi ndi ethanol.
Analogi
Ma Analogs amtundu wotengedwa wa insulin ndi:
- Tidzazitsogolera;
- Gensulin;
- Insulin isophane;
- Insuran;
- Protamine insulin;
- Protafan;
- Rinsulin;
- Rosinsulin;
- Humulin;
- Humulin-NPX.
Kupita kwina mankhwala
Kugulitsidwa kwa makasitomala kokha mwa mankhwala, kuwonetsa kuchuluka kwake. Mutha kuyipeza iyi mwaulere.
Kodi ndingagule popanda kulandira mankhwala?
Popanda kuthandizidwa ndi adotolo, mutha kulipeza ngati mukulipira. Sikugulitsidwa m'mafakitala onse. Kugula insulin popanda kupereka chikalata chachipatala, munthu amadziika pachiwopsezo chachikulu.
Mtengo wa biosulin
Mtengo wa botolo la Biosulin ndi ma ruble 485. Mtengo wa mabotolo 5 wokhala ndi syringe ndi cholembera, cartridge - kuyambira 1067 mpaka 1182 rubles.
Popanda mankhwala a dokotala, Biosulin imatha kupezedwa chindapusa.
Zosungidwa zamankhwala
Sungani kutentha kwa + 2 ... + 8 ° C, pamalo otetezedwa ndi kuwala. Osalola kuzizira.
Tsiku lotha ntchito
Alumali moyo wa mayankho ndi zaka 2. Mukasindikiza, mankhwalawa amatha kusungidwa kwa masabata 6, ndi makatoni kwa masiku 28. Azikhala pamoto wotentha + 15 ... + 25 ° С.
Wopanga
Yopangidwa ndi Marvel Life-Sayansi, India; Pharmstandard Ufa VITA, Russia.
Ndemanga za biosulin
Madokotala
Irina, wazaka 40, wodwala matenda a m'mimba, a Samara: "Pokonza shuga, ndimapereka mtundu wa Biosulin mwachangu komanso wapakatikati. Mankhwalawa amalekeredwa bwino ngati mulingo ndi nthawi yoyendetsera imawerengedwa molondola, zotsatira zoyipa sizinawonekere. masiku, zomwe zikuwonetsa kubwezera kwabwino matenda ashuga. "
Svetlana, wazaka 38, endocrinologist, Rostov-on-Don: "Mtundu wa insulini wothandiza odwala omwe ali ndi matenda a shuga omwe amadalira insulin. Pazomwezi, mtundu wachangu wa mankhwalawa umalembedwa, chifukwa ndikofunikira kulipiritsa kulumpha kwa glucose musanadye. Zimathandizira kuyendetsa bwino shuga patsiku lonse. "
Odwala
Sergey, wazaka 45, ku Moscow: "Ndimatenga Biosulin P ngati imodzi mwa mitundu yochepa ya insulin. Amapezeka ngati theka la ola, ndiye kuti, kuyambitsa mankhwalawa kumatha kulumikizidwa mosavuta ndi chakudya chilichonse. Nthawi zonse ndimasamala kuchuluka kwa insulini kutengera kulemera kwanga kuchuluka kwa chakudya, chifukwa chake zochitika za hypoglycemia ndizosowa. Palibe zotsatira zina zoyipa. "
Irina, wazaka 38, St. Petersburg: "Ndimatenga Biosulin H ngati imodzi mwazosokoneza bongo za insulin. Ndimakonda kugwiritsa ntchito ma syringe apadera: ndi otetezeka komanso odalirika. Nthawi zonse ndimawerengera molondola kuchuluka kwa mankhwalawo ndikuwamwetsa molingana ndi malangizo omwe aphatikizidwa. , zochitika za hypoglycemia nthawi zina zimachitika. Ndaphunzira kuzizindikira ndikuziletsa pakapita nthawi. "
Anthu odwala matenda ashuga
Igor, wazaka 50, Ivanovo: "Ndimagwiritsa ntchito Biosulin ya sing'anga komanso yochepa pakuchiza matenda osokoneza bongo. Ngati ndi kotheka, ndimapaka jekeseni imodzi. Mankhwalawa amathandizira mwachangu komanso samayambitsa shuga, ngati pakanalibe zolemetsa kapena nkhawa m'mbuyomu Poyerekeza ndi jakisoni wa insulin, ndimadya. Zonsezi zimatipatsa mwayi kuti shuga azikhala bwino. "
