Zotsatira zakugwiritsa ntchito Captopril-AKOS mu shuga

Captopril-Akos ndi antihypertensive mankhwala omwe amalimbikitsidwa kuti achepetse kuthamanga kwa magazi.

Dzinalo Losayenerana

Captopril.

Captopril-Akos ndi antihypertensive mankhwala omwe amalimbikitsidwa kuti achepetse kuthamanga kwa magazi.

ATX

C09AA01.

Kutulutsa mafomu ndi kapangidwe kake

Mapiritsi oyera oblong. Pofuna kuchepetsa mlingo, ali ndi chiopsezo chogawanitsa. Mapiritsi aliwonse ali ndi 12.5 mg, 25 mg, kapena 50 mg ya Captopril. Maphukusi a 20 ndi 40 zidutswa.

Zotsatira za pharmacological

Ili ndi mphamvu ya antihypertensive komanso kuthekera kupondereza ntchito ya ACE. Imachepetsa kuwonetsedwa kwa matenda oopsa. Amachepetsa kuchuluka kwa angiotensin 2 opangidwa kuchokera ku angiotensin 1, ndikuyimitsa vasoconstrictor kwenikweni. Amachepetsa kutumiza ndi kutsitsa zotengera zampweya. Zimathandizira kuchepetsa kamvekedwe ka ma arterioles ochita bwino a glomeruli a impso komanso kukonza intracranial hemodynamics. Amaletsa mapangidwe a matenda ashuga nephropathy.

Pharmacokinetics

Ikangokhala m'mimba, imagwidwa mwachangu kuchokera m'matumbo apamwamba. Mkulu kwambiri machulukitsidwe amadzimadzi am'madzi amadziwikiratu pakatha maola 0,5-1,5 mutatha kudya. Kudya munthawi yomweyo kumachedwetsa kuyamwa kwa chinthucho. Biotransformed mu chiwindi. Amayamba kusiya thupi patatha maola atatu atamwa ndi mkodzo. Ndi matenda a impso, nthawi yochotsa theka imatha kufika maola 32.

Captopril-Akos ali ndi antihypertensive kwambiri komanso amatha kupondereza ntchito ya ACE.

Kutulutsidwa - mapiritsi oyera oyera oblong, ali ndi chiopsezo chogawanitsa.

Mkulu kwambiri machulukitsidwe amadzimadzi am'madzi amadziwikiridwa mkati mwa maola 0,5-1,5 mutatha kugwiritsa ntchito mankhwalawa.

Zomwe zimathandiza

Amasankhidwa kuti aphwanye kuthamanga kwa magazi chifukwa cha pathologies monga:

• matenda oopsa;
• kulephera kwa mtima;
• myocardial infarction;
• kuchepa kwa ntchito yamanzere yamitsempha yamagazi;
• matenda ashuga nephropathy.

Contraindication

Sizikudziwika ngati mbiri yachipatala ili ndi zidziwitso pamikhalidwe monga:

• kusalolera kwa mankhwalawa ndi zina za ACE zoletsa;
• kukanika kwa aimpso, kulephera kwa impso;
• kupatsidwa impso;
• matenda a chiwindi, kulephera kwa chiwindi;
• Hyperkalemia
• angioedema;
• bilteryal aimpso mtsempha wamagazi;
• kuthamanga kwa magazi.

Mankhwala sangathe kumwa ndi chiwindi matenda.

Mankhwala sanatchulidwe ngati pali chidziwitso chokhudza kutha kwa impso m'mbiri yamankhwala.

Mankhwala amatchulidwa mosamala mu vuto monga matenda a shuga.

Mankhwalawa sanatchulidwe magazi oyenda.

Mankhwala osavomerezeka kwa anthu ochepera zaka 18.

Captopril-Akos sinafotokozeredwe nthawi yapakati.

Sichimatchulidwa pa nthawi yoyembekezera komanso nthawi yotsatsa. Simalimbikitsidwa kwa anthu ochepera zaka 18.

Amasankhidwa mosamala m'malo monga:

• ischemia;
• matenda amisala;
• hyperaldosteronism;
• matenda a zolumikizana minofu;
• matenda ashuga.

Pamafunika kusintha kusintha kwa mankhwalawa kwa odwala, komanso anthu omwe ali ndi vuto la magazi aimpso komanso akutsutsana ndi hemodialysis.

Mlingo

Njira ndi nthawi yogwiritsira ntchito zimatsimikiziridwa ndi dokotala payekhapayekha.

Ndi myocardial infaration

Lemberani pambuyo masiku awiri kuchokera kumapeto kwa siteji yovuta. Njira Yalangizidwa:

• m'masiku atatu oyamba, tengani 6.25 mg kawiri pa tsiku;
• sabata lotsatira - 12,5 mg kawiri pa tsiku;
• ndiye 2-3 milungu - 12.5 katatu patsiku.

Ndi kulolerana kwaposachedwa kwaposachedwa, chithandizo chamanthawi yayitali chimafotokozedwanso mu 25-50 mg katatu patsiku.

Popsinjika, muyeso woyambirira wa mankhwalawa ndi 12.5 mg maola 12 aliwonse.

Pakanikizidwa

Mlingo woyambirira wa mankhwalawa ndi 12,5 mg maola 12 aliwonse. Voliyumu imodzi imatha kuwonjezeka pambuyo pa masabata a 3-4 oyang'anira. Ndi kuthamanga kwambiri kwa magazi, amapatsidwa mankhwala othandiza a 0,55 g 2 kapena katatu pa tsiku. Mulingo waukulu ndi 0,15 g patsiku.

Kulephera kwamtima kosalekeza

Amawerengera mitundu yovomerezeka ya mankhwala komanso okodzetsa. Mlingo woyambirira ndi 6.25 mg katatu patsiku. Ngati ndi kotheka, mlingo umatha kukula mpaka 25-50 mg (katatu patsiku).

Ndi matenda ashuga nephropathy

Pa magawo oyambirira a mankhwalawa, odwala omwe amadalira insulin ndi omwe amapatsidwa mankhwala ochepa. Pang'onopang'ono, kuchuluka kwake kumakulitsidwa mpaka 25 mg maola 8 aliwonse kapena 0,05 g maola 12 aliwonse.

Momwe mungatenge Captopril-Akos

Amaperekedwa pakamwa ola limodzi asanadye.

Kuwongolera kwapakati kumagwiritsidwa ntchito kuthetsa vuto lalikulu kwambiri.

Pansi pa lilime kapena chakumwa

Palibe deta yovomerezeka pamayendedwe oyendetsera. Amakhulupirira kuti kuwongolera kwapakati kumathandizira kukhazikitsidwa kwa mankhwalawa. Njira iyi imagwiritsidwa ntchito pofuna kuthetsa vuto la matenda oopsa.

Zimatenga nthawi yayitali bwanji

Mulingo woyenera kwambiri umachitika mkati mwa maola 0.5-1,5 mutatha kugwiritsa ntchito.

Ndingamwe kangati

Tengani maola aliwonse 8-12.

Zotsatira zoyipa za Captopril-Akos

Kumwa mankhwalawa kumatha kupangitsa kuchepa kwa magazi, Zizindikiro za tachycardia ndi hypotension. Kuwonetsedwa kwa zovuta zina.

Matumbo

Zovuta za epigastrium, nseru, kusokonezeka mu chakudya cham'mimba, kukoma kwa receptor kukanika, kuchuluka kwa hepatic transaminases. Nthawi zina, kuyambika kwa zizindikiro za hepatitis, kapamba.

Kumwa mankhwalawa kumatha kupangitsa kuchepa kwa magazi.

Mukamwa mankhwalawa, mseru ungachitike.

Odwala ena amakhala ndi magazi m'thupi.

Mukamagwiritsa ntchito mankhwalawa, zizindikiro za tachycardia ndi hypotension zimatha kuchitika.

Mutu ndi chizindikiro cha chapakati chamanjenje.

Odwala ena amayamba kufooka atatha kumwa mankhwalawo.

Hematopoietic ziwalo

Kukula kwa neutropenia, kuchepa magazi, thrombocytopenia, agranulocytosis.

Pakati mantha dongosolo

Mutu, chizungulire, kufooka kwathunthu, kutsika kwa ndende, kuwonetsa paresthesia.

Kuchokera kwamikodzo

Kuwonjezeka kwa ndende ya urea ndi creatinine m'thupi.

Kuchokera ku kupuma

Paroxysmal chifuwa.

Pa khungu

Zotupa pakhungu, kuyabwa, kutentha kwa moto, kumva kutentha kwa thupi, lymphadenopathy.

Kuchokera ku genitourinary system

Oliguria, kusabala.

Pa khungu, zotupa pakhungu, kuyabwa,

Kuchokera pakapumidwe, pamakhala chifuwa cha paroxysmal.

Kuchokera ku genitourinary system, kusabala kungachitike.

Momwe thupi limasokoneza mankhwalawa limawonetsedwa ndi edema ya Quincke.

Mukatha kugwiritsa ntchito mankhwalawa, mumamva kutentha.

Matupi omaliza

Stevens-Johnson syndrome, edema ya Quincke, kukhumudwa kwa anaphylactic, ndi zina zambiri.

Zokhudza mphamvu pakuwongolera njira

Pamafunika kusamala m'magawo oyambira kugwiritsa ntchito.

Malangizo apadera

Hypotension ya Arterial yomwe imawoneka pambuyo pa kumwa mankhwalawa imachotsedwa ndikulipira chinyezi m'thupi.

Kutengera komwe kumamwa mankhwalawo, zimachitika modzitsutsa pakudziwona kwa matupi a ketone.

Gwiritsani ntchito panthawi yoyembekezera komanso mkaka wa m`mawere

Zosavomerezeka.

Kuyenderana ndi mowa

Zosagwirizana.

Kuchulukitsa kwa Captopril-Akos

Kuphwanya dosing regimen ya mankhwalawa kumapangitsa kuti pakhale chidwi chambiri mpaka kupangika kwadzidzidzi kwamtima kulephera (kutayika kwa chikumbumtima komanso kuopseza kufa), kulowerera m'mitsempha, kulowetsedwa kwa magazi kuubongo, kusowa kwa okosijeni, ndi zovuta zina.

Kukula kwa zinthu ngati izi kumafuna chisamaliro chachipatala mwadzidzidzi.

Captopril sigwirizana ndi mowa.

Kuphwanya milingo ya dosing ya mankhwalawa kumabweretsa kuphwanya magazi kuubongo.

Pa mkaka wa m`mawere, mankhwala osavomerezeka.

Captopril-Akos sagwiritsidwa ntchito pazophatikiza ndi mankhwala okhala ndi potaziyamu.

Kuchita ndi mankhwala ena

Musagwiritse ntchito mankhwala ophatikizira omwe ali ndi potaziyamu (odwala omwe ali ndi impso komanso odwala omwe akudalira insulin).

Kuphatikiza pa kugwiritsa ntchito ma immunosuppressants ndi cytostatics, zimatha kupangitsa kukhazikika kwa leukopenia.

Kuphatikiza ndi NSAIDs, kumawonjezera mwayi wa kusokonezeka kwa impso.

Kuphatikiza pa Azathioprine, zimathandizira kukulitsa magazi m'thupi.

Kuphatikiza ndi Allopurinol, kumawonjezera mwayi wokhala ndi zovuta zamagazi ndikuwonjezera zoyipa.

Mafuta akumwa amachepetsa kugwiritsa ntchito erythropoietins, indomethacin ndi ibuprofen.

Imathandizira kukulitsa kuchuluka kwa magazi ndi digoxin.

Zimakhumudwitsa mapangidwe a hypoglycemia limodzi ndi mankhwala a insulin komanso pakamwa.

Analogi

Substit ndi:

• Alkadil;
• Angiopril-25;
• Blockordil;
• Vero-Captopril;
• Kapoten
• Captopril;
• Catopil;
• Epsitron et al.

Kapoten ndi analogue yogwira ya Captopril-Akos.

Mutha kusintha mankhwalawa ndi mankhwala monga Epsitron.

Captopril ndi liwu lofanana ndi Captopril-Akos wokhala ndi mawonekedwe ofanana omwe amatulutsidwa ndi opanga osiyanasiyana.

Mu kapangidwe ka zoloweza mmalo pali kusiyanasiyana kwamankhwala othandizira, kotero kupanikizika kumatha kugwa mwamphamvu komanso mowonjezereka.

Kodi pali kusiyana pakati pa Captopril ndi Captopril-Akos

Masinthidwe ofanana omwe amapangidwa ndi opanga osiyanasiyana.

Kupita kwina mankhwala

Mankhwala Latin.

Kodi ndingagule popanda kulandira mankhwala?

Mankhwala ena opezeka pa intaneti atha kuyitanitsidwadi.

Mtengo wa captopril acos

Mtengo wocheperako mumafakitale aku Russia ndi ma ruble 8 ndi pamwamba.

Zosungidwa zamankhwala

Kutentha kwamtunda 0 ... + 25 ° C. Bisani ana.

Tsiku lotha ntchito

Zaka 5 kuyambira tsiku lopangira.

Wopanga

Synthesis OJSC, Russia.

Ndemanga za madotolo ndi odwala za Captopril-Akos

Telegin A.V., wothandizira, Omsk

Ndi generic wa Kapoten. Kugwiritsidwa ntchito ndi odwala omwe akupanikizika komanso kupumula kwa vuto la matenda oopsa, koma nthawi zambiri amakhala otsika kwambiri kuposa oyamba malinga ndi kugwiririra.

Alina, wazaka 26, Novosibirsk

Mayi anga ali ndi matenda oopsa. Mankhwalawa adamulimbikitsa ndi dokotala pachipatala. Atatha kumwa mankhwalawa, thanzi lake lidayamba kuyenda bwino. Tsopano amayi amangotenga ndi chiwopsezo chodzidzimutsa ndipo amakhulupirira kuti mankhwalawa amamuthandiza bwino.