Maninil ndi piritsi lomwe limagwiritsidwa ntchito pochiza matenda a shuga a 2. Zomwe zimagwira ndi glibenclamide. Amapezeka m'mabotolo a mapiritsi a 120 a pakamwa. 5 mg glibenclamide ali piritsi limodzi.
Zotsatira zogwiritsira ntchito
Manin amachepetsa kuchuluka kwa shuga m'magazi, a gulu la zotumphukira za sulfonylurea.
Maninil odwala matenda ashuga:
- Amachepetsa postprandial (mutatha kudya) hyperglycemia.
- Zilibe phindu lililonse pakusala kudya shuga.
- Amayambitsa kapangidwe ka maselo a b kapangidwe kake kapangidwe ka insulin.
- Lowers wachibale insulin akusowa.
- Zimawonjezera chiwopsezo cha ma receptor apadera komanso zimakhala za insulin.
- Sizikhudza kwambiri insulin kukana.
- Imachepetsa kuphwanya kwa glycogen ndi kaphatikizidwe ka shuga m'chiwindi.
- Imakhala ndi antiarrhythmic athari, imachepetsa mapangidwe am magazi.
- Amachepetsa mwayi wokhala ndi zovuta zotsatirazi za matenda ashuga: angiopathy (zotupa zam'mimba); mtima (matenda a mtima); nephropathy (matenda a impso); retinopathy (matenda a retina).
Zotsatira zake mutatha mannyl zimapitirira kwa maola opitilira 12.
Chithandizo cha matenda ashuga chiyenera kukhala chokwanira komanso kuphatikiza osati mankhwala okha, komanso zakudya
Zizindikiro
Maninil akulimbikitsidwa kuti aikidwe kwa mtundu wachiwiri wa matenda ashuga a mellitus (mawonekedwe osagwirizana ndi insulin) osakhala ndi zotsatira zosakwanira kuchokera ku mankhwala osagwiritsa ntchito mankhwala (zakudya, zolimbitsa thupi zolimbitsa thupi).
Contraindication
Mankhwalawa sagwiritsidwa ntchito mtundu wa matenda ashuga 1 (mawonekedwe a insulin), kutsitsa shuga m'magazi m'munsi mwa manambala, mawonekedwe a zotumphukira zochokera mumkodzo, magazi, kapena nthenda ya matenda ashuga. Maninil sayenera kumwedwa panthawi ya kukomoka ndi mkaka wa mkaka. Amadziwikanso kwa odwala omwe ali ndi mitundu yowonongeka ya chiwindi ndi matenda a impso, ndi tsankho la munthu payekha.
Mlingo ndi makonzedwe
Mlingo wa mankhwalawa komanso nthawi yayitali ya mankhwala amathandizidwa ndi endocrinologist kutengera mlingo wobwezeredwa kwa matendawa. Monga lamulo, mapiritsi amatengedwa 2 pa tsiku, theka la ola musanadye. Pa mankhwala, Mlingo wa mankhwalawa umasinthidwa mpaka njira yothandizidwa itakwaniritsidwa. Mlingo wochepetsetsa wa mankhwalawa ndi mapiritsi a 0,5, pazofunikira zovomerezeka tsiku lililonse ndi mapiritsi atatu.
Maninil ali ndi Mlingo wosavuta, womwe umakupatsani mwayi woti musankhe aliyense wodwala
Zotsatira zoyipa
Zotsatira zotsatirazi zitha kuoneka pakumwa maninil:
- hypoglycemia;
- kulemera;
- zotupa pakhungu;
- kuyabwa
- matenda ammimba;
- kupweteka kwa molumikizana
- magazi kapangidwe ka magazi;
- hyponatremia (kuchepa kwa mulingo wa sodium m'magazi);
- hepatotoxicity;
- mawonekedwe a mapuloteni mumkodzo.
Ndi kuopsa kwa mavuto, mankhwalawa amathetsedwa ndikuchiritsidwa kwina.
Malangizo apadera
Gwiritsani ntchito mosamala mukamatenga clonidine, b-blockers, guanethidine, reserpine chifukwa chovuta kuzindikira zizindikiro za hypoglycemia. Pa chithandizo ndi mannil, kudya ndi kuwunika shuga wamagazi ndikofunikira.
Maninil ayenera kusungidwa m'malo amdima.
Mwambiri, mankhwalawa agwira ntchito bwino pawiri pachipatala cha matenda a shuga 2, komanso kuphatikiza mankhwala ena otsitsa shuga.
