Insulin Lizpro ndi dzina lake lazamalonda

Lyspro insulin ndi mankhwala a ultrashort omwe amadziwika ndi kuyambika mwachangu kwa pharmacological kwenikweni komanso nthawi yochepa yochotsa m'thupi. Chida ichi chimapezeka pogwiritsa ntchito njira zamaumboni komanso njira zopangira ma genetic. Amasiyana ndi insulin wamba ya anthu m'njira inayake ya ma amino acid m'malo ofanana ndi ma CD. Izi sizimangoyipa mphamvu za mankhwalawo, koma zimapangitsa kuti zikhale zopezeka mosavuta komanso zimachulukitsa kuchuluka kwa mayamwidwe.

Zambiri

Lyspro insulin imagulitsidwa pansi pa dzina la malonda la Humalog. Mankhwalawa atha kugulidwa mu ma cartodges a hypodermic kapena mumbale za jakisoni. Iyo, mosiyana ndi mankhwalawa m'makalata, amatha kutumikiridwa osati kokha, komanso intravenly, komanso intramuscularly. Ngakhale kuti mwanjira imeneyi mankhwalawa amatha kusakanizika mu syringe imodzi ndi insulin ya nthawi yayitali, ndibwino kuti musachite izi ndikugwiritsa ntchito zida zamtundu uliwonse pakunyengerera. Chowonadi ndi chakuti zigawo zothandizira zamankhwala zimatha kulowa mosayembekezereka ndikupangitsa zovuta, chifuwa, kapena kuchepa kwa ntchito yogwira ntchito.

Ngati wodwala ali ndi matenda osachiritsika omwe mumayenera kumwa mankhwala ena pafupipafupi, muyenera kudziwitsa endocrinologist za izi. Lyspro insulin imagwirizana ndi mankhwala othamanga kwambiri a magazi komanso kuchuluka kwa ethanol. Mphamvu yake ya hypoglycemic ingachepetse kwambiri mankhwala a mahomoni pochiritsa chithokomiro, mankhwala a psychotropic komanso ma diuretics (diuretics).

Zizindikiro

Mankhwalawa amatha kugwiritsidwa ntchito pochiza odwala omwe ali ndi matenda osiyanasiyana. Monga lamulo, limalekeredwa bwino ndipo kawirikawiri silibweretsa mavuto. Zizindikiro zazikulu zagwiritsidwe ntchito:

• matenda a shuga 1 (makamaka kwa odwala omwe salola bwino kukonzekera insulin);
• kuchuluka kwa shuga mutadya, omwe sangathe kusintha njira zina zochiritsira;
• matenda oopsa a 2 shuga;
• mtundu 2 matenda ashuga owopsa, pokhapokha ngati sipangakhale chakudya chokwanira kuchokera pamapiritsi ochepetsa shuga ndi zakudya;
• kupewa mavuto a odwala matenda ashuga amtundu uliwonse omwe amachitidwa opaleshoni yayikulu.

Chifukwa cha ma molekyulu asinthidwe amtundu wa mankhwalawa mu mankhwalawa, Humalog ikuwonetsa chidziwitso chokwanira chamachuma ngakhale m'gulu ili la odwala matenda ashuga.

Mankhwalawa m'makalata amtunduwu amagwirizana ndi zolembera zomwe zimathandizira kuyika kwake ndipo ndizothandiza kwambiri pakugwiritsa ntchito tsiku lililonse.

Zolemba ntchito

Insulin Degludek ndi dzina lake lazamalonda

Mlingo wofunikira wa lyspro insulin uyenera kusankhidwa ndi dokotala, chifukwa ndi wodwala aliyense. Zowonjezera zake ndikuti mitundu yoposa 40 ya mankhwalawa singagwiritsidwe ntchito nthawi imodzi. Kuchulukanso pazomwe zimalimbikitsidwa kumayambitsa hypoglycemia, chifuwa kapena kuledzera kwa thupi.

Mankhwalawa amayenera kuperekedwa nthawi yomweyo musanadye katatu pa tsiku. Ngati wodwala amathandizidwanso ndi insulin yokhala nthawi yayitali, kuchuluka kwa mankhwala a Humalog kumatha kuchepetsedwa mpaka katatu, kutengera kuchuluka kwa shuga nthawi zosiyanasiyana masana komanso zina zomwe zimachitika pakapita nthawi ya matenda ashuga.

Contraindication ndi zoyipa

Chokhacho chotsimikizika cha lyspro insulin ndi hypoglycemia. Pa mimba ndi mkaka wa m`mawere, mankhwalawa amadziwidwa pokhapokha atakambirana ndi akatswiri omwe amadzidzimutsa. Chifukwa cha kuthupi kwa thupi la mkazi, kufunikira kwa insulini kungasinthe panthawi yomwe mwana akuyembekezera, kotero kusintha kwina kwa mankhwala kapena kusiya kwakanthawi ka mankhwala nthawi zina kumafunikira. Sizikudziwika ngati mankhwalawo akudutsa mkaka wa m'mawere, popeza palibe maphunziro omwe amawongolera pamutuwu.

Zotsatira zoyipa za mankhwalawa zimachitika pafupipafupi. Koma nthawi zina odwala amatha:

• kuchuluka kwa shuga m'munsi mwa gawo lomwe akufuna;
• kutupa ndi kusapeza bwino pa malo a jakisoni;
• lipodystrophy;
• zotupa.

Biphasic insulin

Pali mankhwala osakanikirana omwe amakhala ndi insulin lispro (mahomoni a ultrashort) komanso kuyimitsidwa kwa protamine pa chinthu ichi, chomwe chimakhala ndi nthawi yayitali. Dzina lamalonda lamankhwala awa ndi Humalog Mix.

Popeza izi zimapezeka mu mawonekedwe a kuyimitsidwa (ndiye kuti, zakumwa zokhala ndi tinthu tating'onoting'ono tambiri mkati mwake), cartridge imafunika kuti igulike m'manja mwake isanayambike kuti igawire insulini momwemonso. Osagwedeza mwamphamvu chidebe, chifukwa izi zimatha kupangitsa kuti thovu lipangidwe ndikuwonjezera kuwerengera kwa mankhwala omwe atumizidwa.

Monga mankhwala aliwonse omwe ali ndi matenda ashuga, gawo limodzi komanso gawo lachiwiri la Humalog liyenera kuyikidwa ndi dokotala. Mothandizidwa ndi kuyezetsa magazi, mutha kusankha mlingo woyenera wa mankhwalawa, omwe angakupatseni wodwalayo kukhala wathanzi ndikuchepetsa mwayi wokhala ndi zovuta za matendawa. Simungayesere mwadzidzidzi kusinthira ku mtundu watsopano wa insulin, chifukwa izi zingayambitse kupsinjika kwa thupi ndikupangitsa kuwonongeka.