Kukhala wonenepa kwambiri ndi vuto lodziwika bwino la matenda ashuga. Komabe, kafukufuku waposachedwa akuwonetsa kuti ndikofunikanso kuganizira kuti ndi momwe mafuta amasungidwira m'thupi ndi momwe.
Madokotala adziwa kale mikhalidwe yomwe imakhala kuti chiopsezo chotenga matenda a shuga chikuwonjezereka: zaka kuyambira zaka 45 ndi kupitirira apo, kuthamanga kwa magazi, kukhumudwa, matenda amtima komanso cholowa (milandu ya matenda mwa achibale). Mwinanso choopsa chodziwika bwino ndicholemera kapena kunenepa kwambiri. Koma malinga ndi kafukufuku waposachedwa ndi asayansi aku Britain ndi aku America, ndi mafuta, ngakhale ndiyotani yomwe ili pachiwopsezo, sichosavuta.
Kugawa Mafuta
Pakatikati pa kafukufuku yemwe atchulidwa kale anali mtundu wotchedwa KLF14. Ngakhale sizikhudza kulemera kwa munthu, ndi mtundu womwe umasankha komwe malo ogulitsa mafuta azikasungirako.
Zinapezeka kuti mwa azimayi, mitundu yosiyanasiyana ya KLF14 imagawa mafuta kumasamba amafuta kapena m'chiuno kapena m'mimba. Amayi amakhala ndi maselo ochepa am'mafuta (zodabwitsa!), Koma ndiwokulirapo ndipo kwenikweni "odzaza" mafuta. Chifukwa cha kulimba uku, mafuta osungirako amasungidwa ndikuwadyedwa ndi thupi mosavomerezeka, zomwe mwina zimapangitsa kuti pakhale zovuta zama metabolic, makamaka matenda ashuga.
Ofufuzawo akuti ngati mafuta ochulukirapo amasungidwa m'chiuno, samangokhala mu njira za metabolic ndipo samachulukitsa chiopsezo chokhala ndi matenda ashuga, koma ngati "malo ake" amasungidwa pamimba, izi zimawonjezera kwambiri chiopsezo chomwe chatchulidwa pamwambapa.
Ndikofunika kudziwa kuti kusinthika kotere kwa mtundu wa KLF14, komwe kumapangitsa kuti malo ogulitsa mafuta azikhala m'chiuno, kumawonjezera mwayi wokhala ndi matenda a shuga okha mwa azimayi omwe adawalandira kuchokera kwa amayi. Zowopsa zawo ndizokwera 30%.
Chifukwa chake, zidadziwika kuti pakupanga shuga, osati chiwindi ndi kapamba zomwe zimapanga insulin zimathandizanso, komanso maselo amafuta.
Chifukwa chiyani izi ndizofunikira?
Asayansi sanadziwebe chifukwa chomwe jiniyi imakhudzira ma metabolism okha mwa azimayi, komanso ngati zingatheke kuyika mwambowu kwa abambo.
Komabe, zikuwonekeratu kuti kupezeka kwatsopano ndi gawo limodzi pachitukuko cha mankhwala omwe ali ndi munthu, ndiye kuti, mankhwala potengera mawonekedwe amtundu wa wodwalayo. Mayendedwe awa akadali achichepere, koma olimbikitsa kwambiri. Makamaka, kumvetsetsa gawo la jini la KLF14 kumathandizira kuti adziwe matenda oyambilira kuti awone kuopsa kwa munthu winawake komanso kupewa kuteteza matenda ashuga. Gawo lotsatira likhoza kukhala kusintha mtunduwu kuti muchepetse zoopsa zake.
Pakadali pano, asayansi akugwira ntchito, ifenso, titha kuyambitsa ntchito yodziteteza ku matupi athu. Madokotala amalankhula mosatopa za kuopsa kwa kunenepa kwambiri, makamaka ikafika pa kilogalamu ya kilogalamu, ndipo tsopano tili ndi mkangano umodzi wosatinyoza kulimbitsa thupi ndi kuchita masewera olimbitsa thupi.