Matenda a 2 a matenda a shuga ndi matenda omwe magazi a shuga amawonjezeka mofulumira. Choyambitsa matenda ambiri ndicho kunenepa kwambiri komanso kudya moperewera.
Mankhwalawa matenda amtundu wa 2 shuga, zakudya zapadera zimasonyezedwa. Zimathandizira kuchepetsa shuga wamagazi ndi kusintha kapamba. Komabe, kudya kamodzi sikokwanira.
Odwala amawonetsedwa ngati mankhwala. M'moyo wanu wonse, muyenera kugwiritsa ntchito mankhwala apadera omwe amathandizira kuchepetsa magazi. Glibenclamide imawerengedwa kuti ndi imodzi mwazamankhwala abwino kwambiri amtunduwu (mapiritsi a Glibenclamite nthawi zina amawonetsedwa m'mabuku).
Kufotokozera ndi tanthauzo la momwe mankhwalawo amathandizira
Glibenclamide ndi nthumwi yoyimira sulfonylurea. Mankhwalawa ndi a m'badwo wachiwiri. INN (dzina lopanda tanthauzo padziko lonse lapansi) la mankhwala ndi Glibenclamide.
Kodi mankhwalawa amapangidwa kuti? Glibenclamide (nthawi zina dzina la Glibenclamite Health nthawi zina limapezeka) limapangidwa ku Ukraine. Koma m'mafakitala aku Russia, kugulitsa kwa Glibenclamite Belmed (yoperekedwa ndi Republic of Belarus) kwakhazikitsidwa. M'mbuyomu mu malo ogulitsa mankhwala ku Moscow ndi St. Petersburg adakumana ndi Glibenclamide Thailand (mtengo 5-8 $).
Koma lero, Thailand sikukupanganso chida ichi. Mankhwalawa ndi osiyana ndi amtundu wake. Posachedwa, kusanthula kwa mankhwalawa kwamankhwala kunachitidwa ndi Pankiv, MD. Ntchitoyi idachitika 2010.
Kodi machitidwe a glibenclamides omwe amapezeka pamiyala ndi iti? Mankhwalawa ndi othandizira maselo a pancreatic beta. Mankhwalawa amadziwika ndi kuchuluka kwa mayamwidwe. Micronized glibenclamide (chinthu chomwe chimagwiritsa ntchito mankhwalawa) chimayamba kuchita ngakhale pa mlingo wochepa.
Kuzindikira kwakukulu kwa zinthu kumawonedwa pambuyo pa maola 1-2. Ndizofunikira kudziwa kuti zotsatira mukamamwa mapiritsiwa zimapitirira kwa maola 8-12. Mankhwala samangokhala ndi hypoglycemic.
Malangizowo akuti mukamagwiritsa ntchito mapiritsi a Glibenclamide, kuchuluka kwa cholesterol m'magazi kumatsika. Mankhwala ena amachepetsa mphamvu za m'magazi. Chifukwa cha zovuta, mankhwalawa amayamba kuchitapo kanthu mwachangu. Ma metabolites osagwira a mankhwala amathandizidwa limodzi ndi mkodzo ndi ndulu.
Malangizo ogwiritsira ntchito mankhwalawa
Ndi munthawi ziti zomwe zikuyenera kugwiritsidwa ntchito mankhwalawa? Malangizo ogwiritsira ntchito akuti mankhwalawa amayenera kugwiritsidwa ntchito ngati munthu akudwala matenda osokoneza bongo omwe amadalira kwambiri insulin. Koma njira yothetsera vutoli imakwiririka ngati matenda a shuga akuphatikizidwa ndi zovuta zamagazi.
Pafupifupi tsiku lililonse mankhwala amasankhidwa poganizira zaka za wodwalayo. Malinga ndi malangizo a mankhwala Glibenclamide, mulingo woyenera kwambiri wa okalamba ndi 1 mg. Kwa odwala omwe ali ndi zaka zosakwana 60, mlingo wa tsiku ndi tsiku ndi 2,5-15 mg. Ngati pakadutsa masabata asanu ndi limodzi mulibe momwe mungafunire, ndiye kuti madokotala amapangira chithandizo chamankhwala ndi insulin kapena biguanides.
Kodi ndi choletsedwa kugwiritsa ntchito chiyani glibenclamide? Malangizo akusonyeza kuti zotsutsana:
- Chiwopsezo kwa zigawo za mapiritsi.
- Anthu odwala matenda ashuga komanso comatose.
- Kukhalapo kwa zowotcha zambiri.
- Kulepheretsa kwamkati.
- Kuchepa kwa chiwindi.
- Zowopsa zaimpso.
- Mimba
- Mtundu 1 wa shuga mellitus (wodalira insulin).
- Nthawi yonyamula.
- Leukopenia
- Paresis wam'mimba.
Panthawi yamankhwala othandizira, yang'anirani mosamala Zizindikiro za shuga m'magazi ndi mkodzo. Kudya sikuyenera kuchitika pasanathe ola limodzi mutadya mapiritsi.
Ndi zoletsedwa kumwa mowa nthawi yamankhwala.
Zotsatira zoyipa ndi mtengo wa mankhwala
Popanga mapiritsi a Glibenclamide, pharmacopeia imagwiritsidwa ntchito (malamulo ndi malamulo). Chifukwa chake, chiwopsezo cha zovuta zimakhala zochepa. Koma mukamagwiritsa ntchito mankhwalawa pali mwayi wocheperako.
Ngati mulingo woyenera, hyperglycemia imayamba. Chiwopsezo cha zotsatirapo zake zimakhala chachikulu makamaka ngati wodwalayo amadya kwambiri, zomwe zimapangitsa kuchepa kwakanthawi kwa caloric.
Zovuta monga:
- Kusokonekera mu ntchito yam'mimba. Amawoneka mumtundu wa mseru, matenda am'mimba, kutentha kwa mtima. Nthawi zina - kuwonongeka kwa chiwindi, cholestasis, dyspepsia.
- Chizungulire, migraine, kufooka kwa shuga, kusintha kukoma. Zisokonezo izi zimayamba ngati mumwa mapiritsi olakwika.
- Thupi lawo siligwirizana.
- Kuphwanya kwa hematopoietic dongosolo. Wodwala amatha kupeza leukopenia, thrombocytopenia, kuchepa magazi, eosinophilia, pancytopenia, agranulocytosis.
- Chakumapeto cutaneous porphyria.
- Zithunzi.
- Arthralgia.
- Thupi.
- Proteinuria
- Polyuria
Ndemanga zamakasitomala zikusonyeza kuti zotsatirapo zake ndizosowa kwambiri. Zotsatira zoyipa zilizonse zikachitika, tikulimbikitsidwa kuti musiye chithandizo ndi kulandira chithandizo chamankhwala.
Mtengo wa mapiritsi a glibenclamide ndi uti? Mtengo wa mankhwalawa omwe amachokera ku Ukraine ndi Belarus saposa ma ruble 80-100. Pogula mapiritsi, onetsetsani kuti mwapereka mankhwala oyenera.
Glibenclamide Thailand ikhoza kugulidwa ndi $ 5-8. Chidachi chimagulitsidwa pa intaneti chokha. Mukafuna kuyitanitsa mankhwala kudzera m'machiritsi a pa intaneti, sikofunikira kupereka mankhwala.
Chingagwiritsidwe ntchito bwanji mmalo mwa mankhwalawa? Ndemanga za madotolo zikuwonetsa kuti ma analogues abwino kwambiri ndi Glibamide (30-60 rubles) ndi Maninil (ma ruble a 230-250). Mankhwalawa ndi synibony Glibenclamite, chifukwa chake, ali ndi magwiritsidwe ofanana a zochita, contraindication ndi mavuto.
Ma analogu ena atha kukhala ndi:
- Amapiride (ma ruble 200-220). Mankhwalawa akuyenera kugwiritsa ntchito mankhwalawa matenda a shuga a mtundu wachiwiri. Mankhwala amathandizira kutulutsa kwa insulin kuchokera ku maselo a beta a kapamba. Analogue ya mapiritsi a glibenclamide ndi othandiza kwambiri, koma ali ndi kuchuluka kwa ma contraindication.
- Guwa (ma ruble 600-750). Mankhwalawa amachokera ku Germany. Analogue ya mapiritsi a Glibenclamide ndi othandiza kwambiri. Mankhwalawa adapangira zochizira matenda a shuga a mtundu wachiwiri. Guwa limathandiza kuchepetsa magazi, komanso kusintha kapamba.
- Glimepiride-Teva (ma ruble 200-260). Mankhwala ndi analogue abwino kwambiri a glibenclamide pamapiritsi. Glimeperid amathandizira shuga m'magazi ndi cholesterol. Mankhwalawa amapangidwira zochizira matenda osokoneza bongo omwe amadalira shuga.
Mukamasankha analogue, muyenera kulumikizana ndi madokotala. Mankhwala onse a shuga amakhala ndi zotsutsana zambiri. Pamaso pa kulephera kwa impso kapena chiwindi, kugwiritsa ntchito mawonekedwe a Glibenclamide pamwambapa ndi koletsedwa. Kanemayo munkhaniyi akukamba za kugwiritsa ntchito mankhwala pochiza matenda ashuga.
