Pali mankhwala ambiri omwe amapangidwa kuti azisintha magazi. Metformin kapena Siofor, ndibwino komanso lothandiza kwambiri? Wodwala matenda ashuga akhoza kuyang'aniridwa ndi kusankha komwe angagule ndikugula ndi kusiyana kwake.
Tiyenera kudziwa kuti mapiritsi a Metformin Teva, Glucofage, Siofor ali m'gulu la mankhwala a greatuanide. Komanso, mukamayang'anira mawonekedwe a mankhwalawo, mutha kuwona kuti chinthu chachikulu chomwe chimagwira ndi chimodzimodzi.
Metformin yogwira ntchito ndi gawo lamankhwala ambiri ochepetsa shuga. Ndi gawo lothandizika kuchokera ku gulu la Biguanides a m'badwo wachitatu ndipo limathandizira kuchepetsa milingo yamagazi.
Wothandizira antidiabetesic amalepheretsa ntchito ya gluconeogenesis, kayendedwe ka ma elekitironi a ma kupuma ma mitochondria. Glycolysis imakhudzidwa, maselo amayamba kuyamwa bwino, ndipo mayamwidwe ake ndi makoma am'mimba amachepa.
Zisonyezo zakugwiritsa ntchito mankhwala?
Chimodzi mwazinthu zabwino zomwe zimagwira ntchito ndichakuti sizipangitsa kuti shuga achepetse kwambiri. Izi ndichifukwa choti Metformin si chinthu chosangalatsa chobisalira insulin.
Zizindikiro zazikulu zakugwiritsa ntchito mankhwala opangidwa ndi metformin ndi:
- kukhalapo kwa metabolic syndrome kapena mawonekedwe a insulin kukana;
- Monga lamulo, pamaso pa insulin kukana, kunenepa kwambiri kukukulira kwa odwala, chifukwa cha zotsatira za Metformin ndi kuyang'anira zakudya zapadera zamagulu, kuchepa thupi pang'onopang'ono kumatheka;
- ngati pali kuphwanya kwa kulolerana kwa shuga;
- scleropolicystosis wa thumba losunga mazira kukhala;
- shuga yodalira matenda a shuga monga monotherapy kapena gawo limodzi la chithandizo chokwaniraź¼
- mawonekedwe a shuga omwe amadalira insulin molumikizana ndi jakisoni wa insulin.
Poyerekeza mapiritsi okhala ndi metformin ndi mankhwala ena ochepetsa shuga, zabwino zazikulu za metformin ziyenera kufotokozeredwa:
- Zake pakuchepetsa kukana kwa insulin mwa wodwala. Metformin hydrochloride imatha kuwonjezera kukhudzika kwa maselo ndi minyewa ku glucose wopangidwa ndi kapamba.
- Kutenga mankhwalawo kumayendetsedwa ndi mayamwidwe ake ndi ziwalo zam'mimba. Chifukwa chake, kutsika pang'onopang'ono pakumizidwa kwa glucose m'matumbo kumatheka
- Amathandizira poletsa chiwopsezo cha chiwindi, chomwe chimatchedwa kuperekera shuga.
- Zimathandizira kuchepetsa kulakalaka, komwe ndikofunikira kwambiri kwa odwala matenda ashuga onenepa kwambiri.
- Zimakhala ndi phindu pa cholesterol, kuchepetsa zoyipa ndikuwonjeza zabwino.
Ubwino wamankhwala ophatikizika ndi metformin ndikuwathandizanso kuti athe kuchepetsa njira yamafuta a peroxidation.
Zochita zoyipa komanso kuvulaza komwe kungachitike ndi metformin
Ngakhale kuchuluka kwa zinthu zopangidwa ndi metformin hydrochloride, kugwiritsidwa ntchito molakwika kungayambitse kuvulaza thupi.
Ichi ndichifukwa chake azimayi athanzi omwe akufuna njira zosavuta zochepetsera thupi ayenera kuganizira za kumwa mankhwalawa?
Piritsi imagwiritsidwanso ntchito ngati mankhwala ochepetsa thupi.
Zoyipa zazikulu zomwe zimachitika chifukwa chotenga metformin hydrochloride ndi monga:
- kupezeka kwa mavuto osiyanasiyana ndi m'mimba, makamaka zizindikiro monga mseru komanso kusanza, kutsegula m'mimba, kutulutsa ndi m'mimba,
- Mankhwala amawonjezera chiopsezo cha matenda a anorexia,
- Kusintha kwakumverera kwa kuthekera ndikotheka, komwe kumawonekera pakapangidwe kazitsulo kosasangalatsa kazitsulo pamlomo wamkamwa,
- kutsika kwa kuchuluka kwa vitamini B, komwe amakukakamizani kuti muonjezere mankhwala osokoneza bongo,
- kuwonetsa magazi m'thupi,
- ndi bongo wambiri, pamakhala chiwopsezo cha hypoglycemia,
- mavuto ndi khungu, ngati pali kuwonetseredwa kwa thupi lawo siligwirizana.
Pankhaniyi, Metformin, Siofor kapena mitundu ina yazinthu zopanga zimayambitsa kukula kwa lactic acidosis ngati kuchuluka kwakukulu kwa kuchuluka kwake kumachitika m'thupi. Kuwonetsera koteroko nthawi zambiri kumawonekera ndi kusayenda bwino kwa impso.
Dziwani kuti ndizoletsedwa kumwa mankhwala akazindikira zinthu izi:
- Acidosis mu mitundu kapena pachimake.
- Atsikana pa nthawi yobereka mwana kapena yoyamwitsa.
- Odwala a zaka zopuma pantchito, makamaka atatha zaka makumi asanu ndi limodzi ndi zisanu.
- Kusagwirizana ndi gawo la mankhwalawa, chifukwa kuyambitsidwa kwa ziwengo zovuta ndikotheka.
- Ngati wodwala wapezeka ndi vuto la mtima.
- Ndili ndi myocardial infarction.
- Ngati hypoxia imachitika.
- Pakusowa kwamadzi, komwe kumayambanso chifukwa cha matenda osiyanasiyana opatsirana.
- Kugwira ntchito kwambiri.
- Kulephera kwa chiwindi.
Kuphatikiza apo, wothandizira wa hypoglycemic samasokoneza mucous.
Sizoletsedwa kumwa mankhwala pamaso pa matenda am'mimba (zilonda zam'mimba).
Kodi pali kusiyana pakati pa mankhwala?
Kodi pali kusiyana kotani pakati pa mankhwalawa Metformin, Glformin, Siofor wa matenda ashuga? Kodi mankhwala amodzi ndi osiyana ndi ena? Nthawi zambiri odwala amakakamizidwa kusankha: Glucofage kapena Siofor, Glucofage kapena Metformin, Siofor kapena Metformin ndi zina zotero. Tiyenera kudziwa kuti kusiyana kwakukulu kumangokhala mu dzina la mankhwalawo.
Monga tafotokozera pamwambapa, chinthu chomwe ndi Metformin hydrochloride chimagwiritsidwa ntchito ngati chofunikira chachikulu pazida zamankhwala zotere. Chifukwa chake, zotsatira za kumwa mankhwalawa ziyenera kukhala zofanana (mukamagwiritsa ntchito Mlingo womwewo). Mu
Kusiyanako kungakhale mu zigawo zowonjezera, zomwe zimakhalanso gawo la mapiritsi. Izi ndi zokopa zosiyanasiyana. Mukamagula, muyenera kuyang'anira zomwe ali nazo - ocheperako kuchuluka kwa zowonjezera, ndizabwino. Kuphatikiza apo, dokotala yemwe akupezekapo angalimbikitse kumwa mankhwala ena ake, kutengera mtundu wa wodwalayo.
Mwachitsanzo, Siofor 500 ili ndi mawu awa:
- gawo lalikulu ndi metformin hydrochloride,
- zotuluka - hypromellose, povidone, magnesium stearate, titanium dioxide, macrogol 6000.
Mankhwala Glucophage (kapena Glucophage nthawi yayitali) m'mapangidwe ake ali ndi zinthu izi:
- yogwira mankhwala - metformin hydrochloride,
- monga zina zowonjezera, hypromellose, povidone, magnesium stearate imagwiritsidwa ntchito.
Chifukwa chake, ngati pali kusankha pakati pa Siofor kapena Glucophage wa matenda a shuga a 2, njira yachiwiriyo, yokhala ndi zigawo zochepa, imakhala yoyenera kuphatikizidwa ndi mankhwala.
Posankha mankhwala, munthu amayeneranso kuganizira zinthu monga mtengo wa mankhwalawo. Nthawi zambiri, ma analogi achilendo amakhala ndi mtengo wokwirirapo kuposa mankhwala akwathu. Monga momwe mchitidwe umasonyezera, momwe amalandirira zilinso zosiyana. Mpaka pano, mapiritsi a Metformin ndi njira yabwino kwambiri yowerengera ndalama pakati pa zida zamankhwala zomwe zimakhala ndi metformin hydrochloride.
Ngati wodwala matenda ashuga akukayika kena kake ndipo sakudziwa ngati nkotheka kusintha mtundu wina ndi wina, muyenera kufunsa dokotala. Katswiri wazachipatala amatha kufotokozera za kusiyana pakati pa zida zingapo zachipatala, ndikufotokozanso chifukwa chake mankhwalawa ndi oyenera kwa munthu wina.
Glucophage kapena Siofor - monga momwe malangizo akugwiritsira ntchito?
Mankhwala a Glucophage ndi Siofor ndi ma analogu apangidwe.
Chifukwa chake, momwe ntchito zawo zikuyeneranso kuwonetsedwa.
Nthawi zina dokotala yemwe amapezekapo amapatsa wodwala mndandanda wa mapiritsi a analog ndi mwayi wogula imodzi ya iwo.
Zikatero, zinthu zotsatirazi ziyenera kuganiziridwa:
- Mankhwalawa ayenera kukhala otsika mtengo.
- Ngati ndi kotheka, khalani ndi zowonjezera zochepa.
- Kusiyanako kungakhale mu mndandanda wa contraindication ndi zotsatira zoyipa.
Poyerekeza, ndibwino kugwiritsa ntchito malangizo omwe amagwiritsidwa ntchito pakugwiritsa ntchito mankhwalawa, ndikusankha mankhwala omwe ali oyenera.
Metformin, Glucofage 850 imasiyana ndi Siofor pamakhalidwe awa:
- Glucophage 850 ili ndi mitundu yambiri yosiyanaku. Ndiye chifukwa chake, owerenga ena amawonetsa kuti mankhwalawo sanawakomere.
- Kuyerekeza kumawonetsa kukhalapo kwa zochulukitsa zambiri komanso milandu pomwe sizingatheke kutenga Siofor (mosiyana ndi Glucofage ndi Metformin).
- Mtengo wa Glucofage ndiwokwera pang'ono, pankhaniyi Siofor ndiyabwino.
Dziwani kuti ngati katswiri wodziwa zamankhwala amathandizira kuyang'anira mapiritsi a nthawi yayitali, mtengo wa mankhwalawo umakwera kwambiri. Mwachitsanzo, Glucofage yayitali idzawononga pafupifupi ma ruble mazana atatu ndi mulingo wochepera.
Lingaliro la akatswiri azachipatala ndilakuti mankhwalawa amachepetsa shuga yayikulu magazi, amachepetsa chiwonetsero cha insulin kukana mahomoni ndikuthandizira kuphatikiza cholesterol yabwino. Mapiritsi amatha kusinthidwa, chifukwa chomwe wodwalayo angasankhe njira yabwino kwambiri kwa iye.
Zomwe othandizira a hypoglycemic ndizothandiza kwambiri zikufotokozedwa mu kanema munkhaniyi.
