Colestipol imagwiritsidwa ntchito kwambiri pochiza mabanja hypercholesterolemia.
Mankhwalawa ndi anion exchange resin, omwe adapangidwa kuti asasokoneze ndikuchotsa ma asidi a bile m'matumbo a lumen.
Yogwira pophika mankhwalawa imatha kukhala ndi nkhawa pamene kuyimitsidwa kumachitika chifukwa cha kukula kwa hyperbilirubenemia.
Kuphatikiza apo, mankhwalawa amachepetsa mkhalidwe wodwala chifukwa cha kuledzera kwa glycosidic.
Mankhwalawa ndi mankhwala othandiza kutsekula m'mimba chifukwa cha kuphwanya mayamwidwe am'mimba a bile pambuyo pokhazikika kwa ileamu.
Kutulutsa mawonekedwe ndi mankhwala
Colestipol amapangidwa mwa mawonekedwe a ufa wophatikizidwa m'matumba a magalamu asanu uliwonse komanso mawonekedwe a piritsi wokonzekera piritsi limodzi la gramu imodzi. Mapiritsi ali ndi matuza ndipo amakhala m'matumba a makatoni.
Mtengo wa mankhwala m'dera la Russian Federation ungasiyane pang'ono kutengera dera ladzikolo komanso ma ruble pafupifupi 300.
Mankhwalawa amayenera kusungidwa pamalo otetezedwa ndi dzuwa. Malo osungirako grleles a Colestipol sayenera kupezeka kwa ana ndi ziweto.
Mankhwalawa sayenera kusungidwa pachinyezi chachikulu, ndipo kutentha kwa malo osungirako kuyenera kukhala pakati pa 15 ndi 25 degrees Celsius. Kugula kwa mankhwalawa kumachitika kokha m'mafakisoni pokhapokha ngati mwalandira dokotala. Yogwira pophika mankhwala ndi Colestipol hydrochloride.
Colestipol ndi mankhwala omwe ali ndi lipid-kuchepetsa. Kukhazikitsidwa kwake mthupi kumathandizira kuchepetsa kuchuluka kwa cholesterol yonse komanso kuchepa kwa lipoproteins m'magazi a magazi. Mukadziwonetsa thupi, mankhwalawa samayambitsa kuchepa kwa lipoproteins yapamwamba mu plasma. Mafuta osinthira anion omwe amapanga mankhwalawa amalimbikitsa kumanga kwa bile acid. Zinthuzi zomwe zimakhala zomangika zimachotsedwa m'thupi limodzi ndi ndowe.
Kulumikizana kwa bile acid kumachepetsa kukula kwa njira za mayamwidwe omaliza a m'mimba. Nthawi yomweyo ndi njirayi, kaphatikizidwe ka ma asidi a cholesterol ochokera m'magazi a chiwindi amayamba, komwe kumapangitsa kutsika kwa cholesterol m'thupi.
Malinga ndi malangizo ogwiritsira ntchito mankhwalawa, chisonyezo chachikulu chogwiritsira ntchito ngati mankhwala ochiritsira ndikupezeka kwa mtundu wa 2A hyperlipoproteinemia wodwala. mtundu uwu wa matenda samatha kuwongoleredwa pakuwona zakudya zapadera zamagulu olimbitsa thupi ndikuyika mphamvu pathupi la munthu.
Matenda oyipa omwe mungagwiritsire ntchito mankhwalawa ndi othandizira matenda oopsa komanso kukhala ndi vuto la matenda ena.
Mankhwalawa angagwiritsidwe ntchito onse awiri pa monotherapy, komanso ngati gawo la chithandizo chovuta, monga chimodzi mwazinthu zomwe zimapangitsa mankhwalawo kukhudzanso thupi la wodwalayo.
Malangizo ogwiritsira ntchito mankhwalawa
Musanagule Colestipol, muyenera kudziwa bwino momwe mungagwiritsire ntchito, mtengo wake, ndemanga za mankhwalawa, akatswiri onse azachipatala ndi odwala omwe adagwiritsa ntchito mankhwalawa, tikulimbikitsidwanso kuti mukaonane ndi dokotala kuti mudziwe za kupezeka kwa ma analogu a mankhwalawa.
Malinga ndi malangizo ogwiritsira ntchito, mankhwalawa amathandizidwa kuti azigwiritsidwa ntchito pa mankhwala pa mlingo wa magalamu 5 patsiku. Mlingo woyambayo, ngati ndi kotheka, utha kuwonjezeredwa ndi dokotala. Kuchulukitsa mlingo kumayenera kukhala magalamu 5 aliwonse miyezi iwiri iliyonse.
Ngati mankhwalawa amagwiritsidwa ntchito mu Mlingo wocheperako komanso wapakati, ayenera kumwedwa kawiri pa tsiku. Ndi kuchuluka kwa magalamu opitilira 20 patsiku, mlingo umagawidwa pawiri.
Nthawi zambiri, kutchulidwa kokwanira kotenga Colestipol kumawonedwa pambuyo pa mwezi wogwiritsidwa ntchito mosiyanasiyana mankhwala.
Mlingo woyenera wovomerezeka ndi magalamu 30 patsiku.
Colestipol, monga mankhwala ena ambiri, ali ndi zotsutsana zingapo pakugwiritsa ntchito, zimawaganiziridwa mukamamwa.
Kugwiritsa ntchito mankhwalawa osavomerezeka:
- kukhalapo kwa tsankho kwa magawo a mankhwala;
- sitima;
- Ndi zaka wodwalayo mpaka zaka 6.
Pa mankhwala ndi mankhwala, zotsatirazi zoyipa zimatha kudwala:
- Kuchepetsa mseru
- Kuyimbira kusanza.
- Maonekedwe a hiccups.
- Kudzimbidwa.
- Zachisangalalo.
- Kutsegula m'mimba.
Kuphatikiza apo, nthawi zina, kupezeka kwa urticaria ndi dermatitis.
Mogwirizana ndi mankhwala, malangizo apadera ndi fanizo la mankhwala
Ngati pali contraindication wodwala, n`zotheka ntchito analogues ake achire othandizira.
Zotsatira za mankhwalawa ndi mankhwala monga Lipantil, Lipantil 200 M, Tribestan, Roxer, Vitrium Cardio Omega-3 wa cholesterol.
Malinga ndi malingaliro omwe afotokozedwa mu malangizo ogwiritsira ntchito, mukamagwiritsa ntchito Colestipol, mankhwalawa omwe amatengedwa nawo ayenera kuganiziridwa.
Mankhwala ambiri amatha kusokoneza ntchito ya Colestipola.
Mankhwala otsatirawa amakhudza ntchito ya Colestipola:
- Atorvastatin - amachepetsa ndende ndikuwonjezera mphamvu ya lipid;
- Vancomycin - limamanga ntchito yogwira;
- Gemfirozil - amachepetsa adsorption ya chinthu chogwira;
- Hydrocortisone - otsitsa adsorption.
Kuphatikiza apo, kugwiritsidwa ntchito kophatikizana kwa tetracycline, Furosemide, Pravastatin, Carbamazepine, Diclofenac ndi ena ena amathandizika pakugwira ntchito ya zigawozi.
Musanalembe mankhwala, onetsetsani kuti wodwalayo alibe:
- Hypothyroidism
- Mtundu woyamba wa shuga.
- Dysproteinemia syndrome.
- Zowopsa za thirakiti lothandiza.
Pamaso pa izi, mankhwalawa amatha kuloledwa, koma kukhazikitsa kwake kuyenera kuchitika moyang'aniridwa ndi adokotala.
Munthawi yonse ya chithandizo ndi mankhwalawa, kuyang'anira kolesterol, lipoprotein, ndi magulu a TG ndikofunikira.
Mankhwala sayenera kuthandizidwa ndi Colestipol panthawi ya bere. Izi ndichifukwa choti palibe chidziwitso chazomwe zimapangitsa kuti mankhwala azitha kugwira ntchito pa mwana wosabadwayo ndi momwe mayi alili panthawiyi. Kuphatikiza apo, mankhwalawa sayenera kugwiritsidwa ntchito pochiritsa pakumwa poyamwitsa, popeza palibe deta yodalirika yokhudzana ndi zomwe zimachitika pokhudzana ndi mkaka wamawere.
Zokhudza mankhwala a cholesterol okwanira omwe afotokozedwa muvidiyoyi.
