Lyspro insulin ndi chinthu chofanana ndi insulin ya anthu. Amapangidwira anthu omwe akuvutika ndi glucose. Mu mkhalidwe wa pathological uwu, hyperglycemia imayamba chifukwa cha kuchepa kwa insulin.
Dzinalo Losayenerana
Humalog - dzina lamalonda la mankhwala ku Russia.
Lyspro insulin ndi mankhwala a INN.
Insulin lispro - dzina la latini.
Lyspro insulin ndi chinthu chofanana ndi insulin ya anthu. Amapangidwira anthu omwe akuvutika ndi glucose.
ATX
Ndondomeko mu anatomical ndi achire mankhwala gulu gulu ndi A10AB04. Khodi ya gulu ndi A10AB (omwe amangotenga ma insulin ndi ofanana nawo).
Kutulutsa mafomu ndi kapangidwe kake
Mankhwalawa amapangidwa mwa mawonekedwe amadzimadzi kulowa jakisoni kapena pansi pa khungu. Mankhwalawa amagulitsidwa m'mitundu iwiri:
- mu phukusi la makatoni okhala ndi ma syringe a 5 Quick Pen (3 ml iliyonse, 100 IU / ml), okonzeka kugwiritsa ntchito;
- mu katoni wamakalata ndi makatoni 5 (3 ml iliyonse, 100 IU / ml).
Yogwira ntchito ya mankhwala amatchedwa lyspro insulin. Zowonjezera: metacresol, glycerol, madzi a jakisoni, 10% yankho la hydrochloric acid, etc.
Zotsatira za pharmacological
Mankhwalawa ali ndi vuto la hypoglycemic. Pambuyo pokonzekera intravenous kapena subcutaneous, shuga m'magazi amachepetsa. Zotsatira zake zimachitika pafupifupi mphindi 10-20 pambuyo pa kugwiritsa ntchito mankhwalawa.
Mankhwalawa ali ndi vuto la hypoglycemic. Pambuyo pokonzekera intravenous kapena subcutaneous, shuga m'magazi amachepetsa.
Pharmacokinetics
Mankhwala omwe amagwira ntchito amakhala othamanga mwachangu, chifukwa amakhala ndi mafuta ambiri ochulukirapo (ndi gawo la gulu lama insulin). Chifukwa cha izi, munthawi yochepa kwambiri kuchuluka kwa plasma kumatheka (osachepera theka la ola pambuyo pake).
Mankhwalawa amatha kubayidwa m'mitsempha kapena pansi pa khungu pakudya. Amaloledwa kuyika jekeseni pasadakhale, kupitilira mphindi 15 asanadye. Kuchuluka kwa zochitika kumachitika pambuyo pa maola 1-3, ndipo nthawi ya mankhwalawa imachokera ku maola atatu mpaka asanu. Kuchotsa theka-moyo pafupifupi ola limodzi.
Zizindikiro zogwiritsidwa ntchito
Madokotala amapereka mankhwala kwa odwala awo omwe ali ndi matenda ashuga. Mothandizidwa ndi mankhwalawa, mankhwala a insulin amachitidwa, omwe amakupatsani mwayi wokhala ndi shuga m'magazi pamlingo woyenera.
Contraindication
Mankhwala sangathe kugwiritsidwa ntchito:
- ndi hypersensitivity pazogwira ntchito kapena zowonjezera kuchokera ku Humalogue;
- ndi kuchepa kwa shuga m'magazi m'munsi mwa mulingo woyenera (3.5 mmol / l).
Ndi chisamaliro
Ndikofunikira kupaka jakisoni mosamala kuti musalowe mumtsempha wamagazi. Pambuyo pa jekeseni, khungu silifunikira kuti lizipukutidwa.
Momwe mungatengere insulin lyspro
Zomwe mungagwiritse ntchito ndi mlingo wake ziyenera kutsimikiziridwa ndi ogwira ntchito zachipatala payekhapayekha. Nthawi zambiri, insulin imayendetsedwa mosavomerezeka. Kuwongolera kwamitsempha kungakhale kofunikira nthawi zina (mwachitsanzo, pakatikati pa kuchitapo kanthu kwa opaleshoni kapena pambuyo pawo, ndi matenda omwe amapezeka mumitundu yambiri, kuperewera kwa insulini komanso kuchepa kwa chakudya cha metabolism).
Mukamagwiritsa ntchito mankhwalawa, ndikofunikira kutsatira malangizo oyambitsa jakisoni. Wodwala amafunikira:
- Konzani mankhwala. Iyenera kuyenerana ndi mawonekedwe monga mawonekedwe, mawonekedwe. Kubweretsa yankho kumatayidwa ngati kuli kwamtambo, kokhazikika. Mankhwala ayenera kukhala ndi kutentha kwa chipinda.
- Sambani manja anu ndikusankha malo a jakisoni wothira pokonza.
- Phatikizani singano ku cholembera ndikuchotsa kachipewa kotchinga.
- Musanalowetse khungu m'malo osankhidwa kuti musonkhe, kuti khola lalikulu lipezeke, kapena kutambalala.
- Ikani singano m'malo osakonzeka ndikudina batani.
- Chotsani singano mosamala pakhungu ndikuikamo swab ya thonje kumalo a jekeseni.
- Pogwiritsa ntchito chipewa choteteza, chotsani singano. Nthawi ina mukadzagwiritsa ntchito mankhwalawa, mufunika singano yatsopano.
Chizindikiro chodziwika bwino chakamagwiritsa ntchito insulin lyspro ndi hypoglycemia.
Zotsatira zoyipa za insulin lyspro
Chizindikiro chodziwika bwino cha mbali ndi hypoglycemia. Woopsa milandu, hypoglycemia kumabweretsa kukomoka. Komanso, ndi shuga wochepa wamwazi pali chiopsezo cha kufa.
Mukamagwiritsa ntchito mankhwalawa, mungakumane ndi ziwengo. Mawonekedwe ake amawonetsedwa kawirikawiri pamalo opangira jekeseni. Odwala, khungu limafupika ndikutupa, kuyabwa kumachitika. Zizindikiro zimachoka pakapita kanthawi. Kaŵirikaŵiri thupi siligwirizana. Kuchita kwa thupi koteroko kumatha kukhala pangozi. Zizindikiro za thupi lawo siligwirizana:
- totupa thupi lonse;
- kuyabwa
- Edema ya Quincke;
- thukuta;
- dontho la kuthamanga kwa magazi;
- kuchuluka kwa mtima;
- kupuma movutikira
- malungo.
Chothekera china chowopsa ndikusowa kwa mafuta obwerera m'mimba (lipodystrophy). Izi ndizotengera kwanuko. Itha kuwoneka mbali ya thupi momwe jekeseni wa mankhwala adayendetsera.
Zokhudza mphamvu pakuwongolera njira
Mankhwala amatha kuvulaza kuyendetsa galimoto komanso njira zingapo zovuta zomwe zimafuna chidwi chochulukirapo komanso mosamala, pazochitika ziwiri:
- ndi kuyambitsa mlingo wowonjezera kapena wochepetsedwa komanso kukula kwa hyperglycemia kapena hypoglycemia chifukwa cha izi;
- ndi mawonekedwe a hypoglycemia ngati mbali yotsatira.
M'magawo onse awiri, kuthekera kwakukuru kumayipa, ndipo zochitika zama psychomotor zimachepetsa. Kuyendetsa ndi kugwira ntchito ndi makina ovuta kumalimbikitsidwa mosamala.
Malangizo apadera
Poyang'aniridwa ndi akatswiri, wodwala amayenera kupita ku insulin ina. Kusintha kwa Mlingo kungafunike pakusintha wopanga, mtundu wa mankhwala, njira yopangira, ndi zina zambiri.
Gwiritsani ntchito mu ukalamba
Insulin iyi imatha kuperekedwa kwa anthu okalamba. Malangizo ofunikira kwa gulu la odwala - Mlingo wofotokozedwa ndi dokotala amayenera kuonedwa mosamala kuti achepetse vuto la hypoglycemia. Mkhalidwe uwu ndiwowopsa mukakalamba. Mphamvu ya hypoglycemic imatha kubweretsa vuto lalikulu, kupanikizika kwa ziwiya zam'mimba ndi kulowetsedwa kwa myocardial, kuwonongeka kwa masomphenya.
Kupatsa ana
Humalogue imatha kulembedwa kwa mwana ngati ali ndi matenda ashuga.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Pa nthawi yoyembekezera komanso mkaka wa m'mawere, Humalog ingagwiritsidwe ntchito. Akatswiri omwe adapereka mankhwalawa kwa odwala awo sanawulule zosafunikira. Kafukufuku wasonyeza kuti analogue ya insulin ya anthu:
- samadutsa placenta;
- sizimayambitsa kubadwa mwatsopano;
- sizimayambitsa kulemera kwa akhanda.
Humalogue imatha kulembedwa kwa mwana ngati ali ndi matenda ashuga.
Pa nthawi yoyembekezera, ndikofunikira kutsatira malangizo a dokotala, onani mlingo wake. M'miyezi itatu yoyambirira, kufunafuna insulini kumakhala kotsika. Kuyambira kuyambira miyezi 4, zimachuluka, ndipo pakubala komanso pambuyo pawo zimatha kuchepa kwambiri. Panthawi yoyamwitsa, mlingo wake umasinthidwa ndipo / kapena zakudya zimayikidwa.
The ntchito aimpso kuwonongeka
Ndi ziwalo zosokonekera zamkodzo, kufunika kwa mahomoni kumatha kuchepa.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Ndi ntchito ya chiwindi chovuta, kuchepa kwa kufunika kwa insulin ndikotheka.
Lyspro insulin kwambiri
Kugwiritsa ntchito molakwika mankhwalawa. Mwanjira imeneyi, zizindikiro za hypoglycemia zimawonekera:
- ulesi;
- thukuta kwambiri;
- kulakalaka;
- kuchuluka kwa mtima;
- mutu;
- chisokonezo cha kugona;
- Chizungulire
- kuwonongeka kwamawonekedwe;
- kusanza
- chisokonezo;
- kusokonezeka kwa galimoto, yodziwika ndi kuyenda mwachangu kwa thunthu kapena miyendo.
Panthawi yapakati, Humalog ingagwiritsidwe ntchito, popeza akatswiri sanawulule zotsatira zosafunikira.
Hypoglycemia imayenera kuthetsedwa. Muzochepa, muyenera kumwa shuga kapena kudya zina zomwe zili ndi shuga. Pazovuta kwambiri komanso ndi chikomokere, thandizo la akatswiri likufunika. Madokotala omwe ali ndi odwala omwe ali ndi zizindikiro za hypoglycemia amapaka jakisoni (m'misempha kapena pansi pa khungu) kapena yankho la glucose (mu mtsempha). Pambuyo pochita zithandizo zotere, umafunika kudya chakudya chokhala ndi chakudya chambiri.
Kuchita ndi mankhwala ena
Ndi munthawi yomweyo makonzedwe a insulin ndi pakamwa kulera, glucocorticosteroids, ma tridclic antidepressants, thiazide diuretics ndi mankhwala ena, zotsatira za hypoglycemic zitha kuchepa. Tetracyclines, sulfanilamides, angiotensin kutembenuza ma enzyme zoletsa, etc. zimapangitsa kuchuluka kwa pharmacological.
Sizoletsedwa kusakaniza insulin iyi ndi mankhwala okhala ndi insulin ya nyama.
Kuyenderana ndi mowa
Kumwa zakumwa zoledzeretsa zam'kati mwa matenda a shuga sikulimbikitsidwa. Ndi kuphatikiza kwa mowa ndi insulin, zotsatira za hypoglycemic zimatheka.
Gulu lina la ma insashins a ultrashort amathandizidwa ndi insulin.
Analogi
Gulu lodziwika bwino kwambiri la insulin limaphatikizapo osati Humalog zokha, komanso mawonekedwe ake - Humalog Remix 25 ndi Humalog Remix 50. Mankhwalawa amapezeka mwanjira yoyimitsidwa pakhungu.
Gulu lina la ma polashort insulins limathandizidwa ndi insulin aspart (mankhwala: NovoRapid Flexpen, NovoRapid Penfill) ndi insulin glulizin (mankhwala: Apidra, Apidra SoloStar).
Palinso insulin za nthawi yanji yochitapo kanthu:
- Zochita zazifupi. Mankhwala ochokera pagululi: Rinsulin R, Humulin Regular, etc.
- Magawo awiri (insulin biphasic - "bifazik"). Kukonzekera: Humodar K25-100, NovoMix 50, Flexpen, NovoMix 30, Penfill, etc.
- Kutalika kwapakati. Gululi limaphatikizapo Biosulin N, etc.
- Kuchita motalika. Mankhwala ena: Lantus, Levemir Penfill.
- Kuchita kwanthawi yayitali. Gululi limakhala ndi mankhwala a nthawi yayitali komanso nthawi yayitali.
Kupita kwina mankhwala
Kodi ndingagule popanda kulandira mankhwala?
Mankhwalawa amagulitsidwa m'mafakisoni okha ndi mankhwala.
Lyspro insulin mtengo
Paketi ya Humalog yokhala ndi cholembera cha syringe imakhala pafupifupi ma ruble 1690. Mtengo pafupifupi wa phukusi wokhala ndi ma cartridge 5 ndi 1770 rubles.
Zosungidwa zamankhwala
Mankhwala omwe sanasindikizidwe amayenera kusungidwa mufiriji kutentha osagwa pansi pa 2 ° C (yankho siyenera kuzizira).
Mankhwala omwe amagwiritsidwa ntchito tsiku lililonse ayenera kusungidwa kutentha (osapitirira 30 ° C). Iyenera kukhala kutali ndi dzuwa ndi zida zamagetsi. Kutalika kwa yosungirako sikuyenera kupitilira masiku 28.
Mankhwala omwe sanasindikizidwe amayenera kusungidwa mufiriji kutentha osagwa pansi pa 2 ° C (yankho siyenera kuzizira).
Tsiku lotha ntchito
Ngati mankhwalawo sanatsegulidwe, amatha kusungidwa kwa zaka 3 kuyambira tsiku lopangira.
Wopanga
Wopanga insulin pansi pa dzina la amalonda Humalog ndi kampani yaku France ya Lilly France.
Malonda a Lyspro insulin
Stanislav, wazaka 55, Tyumen: "Pafupifupi zaka 10 zapitazo ndidapezeka ndi matenda ashuga.Mapiritsi adalembedwa koyambirira kwamankhwala. Posachedwa, katswiri adalimbikitsa kusintha kwa Humalog yankho laukadaulo wapadera, popeza mapiritsi sanaperekepo chidwi chake. Malangizo a adotolo. Ndinagula mankhwalawo ku pharmacy ndipo ndinayamba jekeseni katatu patsiku musanadye. Ndikumva bwino ndikuyerekeza ndi nthawi yomwe mapiritsi sanathandizenso. "
Elena, wazaka 52, Novosibirsk: "Ndili ndi matenda a shuga. Kuti ndisungunuke shuga, ndimadzipaka jakisoni. Malinga ndi malangizo a dotolo wanga, ndimagula Humalog m'mapensulo opindulitsa. Nditengera zolakwira kwambiri zolakwika. "
Anastasia, wazaka 54, Khabarovsk: "Mankhwalawa amagwiritsidwa ntchito moyenera. Sindinatsatire malangizo a dotolo, chifukwa chake nthawi zambiri ndimakhala ndi zovuta. Anthu omwe ali ndi matenda osokoneza bongo salangiza kulakwitsa chimodzimodzi. Tonsefe timazolowera kuchiritsa patokha. , chimfine. Matenda a shuga ndi matenda omwe amafunikira njira yoyenera. M'mathandizidwe ake, ndikofunikira kutsatira mosamalitsa kuikidwa kwa akatswiri. "
