Flemoklav Solutab ili ndi kuphatikiza kwa antibacterial wothandizila ndi enzyme inhibitor. Ichi ndi mankhwala padziko lonse pochizira matenda opatsirana a bakiteriya.
ATX
J01CR02
Kutulutsa mafomu ndi kapangidwe kake
Fomu ya muyeso ya mapiritsi omwazika imapangidwa imakhala ndi izi:
- mawonekedwe oblong;
- mtundu woyera wokhala ndi mawanga a bulauni;
- Zolemba zokhudzana ndi kulembera;
- gawo la logo yopanga.
Zomwe zimagwiritsidwa ntchito ndizotsekedwa m'makola, zomwe zimawonjezera kuyamwa, bioavailability wa mankhwalawa.
Fomu ya Mlingo uli mu mawonekedwe a mapiritsi omaliza.
Piritsi lililonse lili ndi mawu ake:
- amoxicillin trihydrate;
- potaziyamu clavulanate;
- obwera.
Mulibe glucose, mankhwala allergenic, mankhwala ena oyipa.
Kumvera polemba mankhwalawa. Zikuwonetsa zomwe zili pazomwe zimagwira. Amoxicillin + clavulanic acid mu chidutswa chimodzi chalemba.
- "421" ikufanana ndi mlingo wa 125 mg + 31.25 mg;
- "422" akuwonetsedwa pa mlingo wa 250 mg + 62,5 mg;
- "424" anagwiritsa ntchito mlingo wa 500 mg + 125 mg;
- "425" ikufanana ndi mlingo wa 875 mg + 125 mg.
Atadzaza matuza 4 ma PC. wolemba "421", "422", "424". 7 ma PC. - cholembedwa "425". Wopezeka mukatoni kamatundu a matuza 2 ndi 5.
Atadzaza matuza 4 ma PC. wolemba "421", "422", "424".
Njira yamachitidwe
Mitundu yosiyanasiyana ya zochita zamapiritsi imapereka kulumikizana kwa antibacterial wothandizila ndi enzyme inhibitor ya wothandizira matenda.
Chifukwa cha kuletsa kwa kaphatikizidwe ka beta-lactamases, kukula ndi kukula kwama cellorganism kumasokoneza. Mwanjira ya monotherapy sagwiritsidwa ntchito.
Pamodzi ndi maantibayotiki timagwiritsa ntchito bacteria yovuta kwambiri motsutsana ndi zovuta zingapo za mabakiteriya a pathogenic.
Kuphatikiza kwa zinthu ziwiri kumapereka chithandizo chokwanira, chomwe chimadziwoneka ngati:
- onjezerani chitetezo cha antibacterial;
- kupititsa patsogolo ntchito za antimicrobial;
- kukulitsa mawonekedwe owoneka.
Kutalika kwa kugwiritsa ntchito kumawonjezeka chifukwa cha kupangika kwa zinthu zochizira kuzungulira kwazinthu zosiyanasiyana komanso ziwalo za thupi.
Kuphatikiza kwa zinthu ziwiri kumapereka chokwanira chothandizira, chomwe chimadziwonetsa mu mawonekedwe a antibacterial chitetezo chokwanira.
Pharmacokinetics
Magawo onse a mankhwalawa amakhala ndi mayamwidwe ambiri, samadziwika ndikuwonongeka kwa chilengedwe cha acid. Mafuta osungirako zakudya popanda kudya.
Kutulutsidwa kwa michere ndi zinthu zomwe zimachitika pang'onopang'ono. Zomwe zimapangidwa ndizopatukana kwathunthu ndi filler mu duodenum.
Kuthamanga kwakukulu kwa mankhwalawa kumatsimikiziridwa ndi mawonekedwe a Solutab, mosasamala kanthu za njira yoyendetsera. The bioavailability wa amoxicillin ndi 94%. Kwa choletsa ma enzyme obwera, chiwerengerochi chimafika pa 60%.
Magawo onse a mankhwalawa amakhala ndi mayamwidwe ambiri, samadziwika ndikuwonongeka kwa chilengedwe cha acid.
Amamangilira mapuloteni a plasma 20% ya zomwe zimagwira. Kukonzekera kwa pakamwa kumalola kuchuluka kwa magazi pambuyo pa maola awiri. Zizindikiro zamtundu uliwonse wamasulidwe zimawonetsedwa mu malangizo ogwiritsa ntchito.
Pang'ono ndimathiridwe ndi ndulu. Hafu ya moyo imatengera mlingo wa mankhwalawo komanso magwiridwe antchito a impso.
Chifukwa chake, pambuyo pakukonzekera pakamwa pa mlingo wa 375 ndi 625 mg wa amoxicillin, theka la moyo ndi ola limodzi ndi maola 1.3, motero. Imagawidwa ndi impso.
Imagonjetsa mosavuta chotchinga, pang'ono zimatulutsidwa mkaka wa m'mawere.
Zizindikiro zogwiritsidwa ntchito
Kapangidwira zochizira matenda opatsirana.
Matenda opatsirana pakapumidwe koyenera, matenda a pakhungu.
Amagwiritsidwa ntchito kwambiri pa matenda a sinusitis, atitis media, tonsillitis.
Kugwiritsa yotupa matenda a genitourinary gawo.
Mlingo waukulu wa mankhwalawo ndi chifukwa chomveka cha mankhwalawa osteomyelitis, matenda aularular.
Mawonekedwe apadera ndi kukhalapo kwa mankhwala awiri othandizira amalola kugwiritsa ntchito mankhwalawa, mosasamala kanthu za zovuta komanso kutengera kwazomwe zimayambitsa matenda.
Contraindication
Sichikuperekedwa pamaso pa ziwengo zamphamvu zomwe zimagwira.
Contraindified mu matenda mononucleosis.
Kugwiritsa ntchito mankhwalawa kumachepetsedwa ndi zigawo zam'mbuyomu za cholestatic jaundice.
Ndi choletsedwa mulingo woyenera wa ana osaposa zaka 12 omwe ali onenepa.
Khansa ya m'magazi ndi kuphwanya kugwiritsa ntchito mankhwalawa.
Ndi chisamaliro
Flemoklav amatchedwa ndi kusamala mu matenda akulu a chiwindi, m'mimba, matumbo.
Mlingo payekha. Mu kwambiri aimpso, ndizovomerezeka kuperekera mankhwalawa musanadye dial 1 ndi pambuyo.
Sichikuperekedwa pamaso pa ziwengo zamphamvu zomwe zimagwira.
Momwe angatenge
Kwa akulu ndi ana okalamba, mankhwala ophatikiza a antibacterial amadziwikiridwa pakapangidwe kakang'ono ndi pafupipafupi makonzedwe osapitirira katatu patsiku. Mitundu yodziyikira ndiyovomerezeka:
- sungunulani mu 50 ml ya madzi, mukumalimbikitsa mpaka mutasungunuka kwathunthu;
- kumeza lonse ndi madzi;
- sungunulani mkamwa.
Panthawi yoopsa ya matenda opatsirana, ndikubwereza pafupipafupi kwa matenda osachiritsika, kubwereza kawiri kwa mlingo ndikololedwa.
Kwa akulu ndi ana okalamba, mankhwala ophatikiza a antibacterial amadziwikiridwa pakapangidwe kakang'ono ndi pafupipafupi makonzedwe osapitirira katatu patsiku.
Musanadye kapena musanadye
Kudya sikukhudza kinetics wa mankhwalawa. Popewa zoyipa m'mimba ndi m'matumbo, ndibwino kumwa nthawi yomweyo musanadye.
Njira iyi imakhala yovuta kukhumudwitsa mucous nembanemba.
Masiku angati kumwa
Kutalika kwa kuvomerezedwa kumadalira kukula kwa mkhalidwe, zaka, kukula kwa mavuto. Kutalika kwa mankhwalawa sikuyenera kupitirira masiku 14. Ndizosatheka kupitiliza kugwiritsa ntchito mankhwalawa.
Kutalika kwa kayendetsedwe kutengera zovuta za momwe zinthu ziliri, zaka, kukula kwa zovuta, nthawi yayitali sayenera kupitirira masiku 14.
Kodi ndizotheka kumwa mankhwalawa chifukwa cha matenda ashuga
Ubwino wa mitundu yamapiritsi ndi kusapezeka mu kapangidwe kake ka gluteni, glucose, osiyanasiyana allergen. Mayamwidwe yogwira mankhwala sikukhudza glycemia. Izi zimapangitsa kugwiritsa ntchito mankhwalawa pochiza matenda a bakiteriya omwe ali ndi odwala matenda a shuga.
Zotsatira zoyipa
The zimachitika zosafunika mbali zimachitikira limodzi ndi munthu tsankho la yogwira zigawo zikuluzikulu, poika waukulu waukulu. Zotsatira zoyipa zimasinthidwa.
Hepatitis imayamba. Kuwonjezeka kwa hepatic transaminases kumadziwika kwambiri. Nthawi zina, zovuta zamtunduwu wa hepatobiliary zinali zovuta chifukwa cha kuchepa kwa chiwindi.
Mutha kugwiritsa ntchito chida pochiza matenda oyamba ndi bakiteriya omwe ali ndi matenda ashuga.
Matumbo
Osatengera zaka, kumwa mankhwala kumayendera limodzi ndi m'mimba, kusanza. Zizindikiro zotere zimachitika nthawi zambiri mukamagwiritsa ntchito Mlingo waukulu. Ndizosakhalitsa mwachilengedwe, osasiyana pakulimba.
Kutsegula m'mimba kosalekeza kumabweretsa kukula kwa nembanemba colitis. Nthawi zina, matumbo a candidiasis, hemorrhagic colitis, gastritis, ndi stomatitis amakula.
Hematopoietic ziwalo
Magulu a hematopoietic dongosolo la leukopenia, thrombocytopenia, agranulocytosis samachitika. Kutalika kotheka kwa nthawi ya magazi. Izi zimachitika ndikusinthanso.
Osatengera zaka, kumwa mankhwala kumayendera limodzi ndi m'mimba, kusanza.
Pakati mantha dongosolo
Mphamvu ya mankhwala ophatikiza antibacterial akhoza kuchitika:
- kumverera kwa nkhawa;
- Kuda nkhawa
- chizungulire
- kusintha kwamachitidwe.
Kukokana kovuta kwambiri kumayamba. Kuchotsa kuledzera, mawonekedwe onse osafunikira amatha.
Zotsatira za mankhwala ophatikiza antibacterial zitha kuwonetsedwa ndi nkhawa.
Kuchokera kwamikodzo
Osowa. Amalumikizidwa ndi kuphatikiza kwa ntchito othandizira okodzetsa, ntchito yaimpso. Kuwonetsedwa ndi kukula kwa hematuria, kuchotsa makhiristo amchere, zizindikiro za interphitial nephritis.
Matupi omaliza
Maonekedwe a kuyabwa, urticaria, erythroderma ndi mawonekedwe a thupi lawo siligwirizana. Kuyankha kwa chitetezo chathupi kumawonetsedwa ndi kukula kwa anaphylactic, hemorrhagic vasculitis. Mwinanso kukulitsa kwa khungu la mziwala, edema ya Quincke. Milandu ya fever, mankhwala osokoneza bongo, komanso edema. Zomwe zimachitika nthawi yomweyo zimafuna kusiya kwa mankhwalawo komanso kusamalidwa kwambiri.
Maonekedwe a kuyabwa, urticaria, erythroderma ndi mawonekedwe a thupi lawo siligwirizana.
Malangizo apadera
Kugwiritsa ntchito kwa mankhwala kukopa mapangidwe a magazi kumafuna kugwiritsidwa ntchito mosamala ndi anticoagulants.
Kupezeka kwa matenda am'mimba thirakiti ndi kutsegula m'mimba, nseru, ndi kusanza ndizomwe mungaletse mankhwala osokoneza bongo. Mu izi, malabsorption a mankhwalawa amayamba. Amawerengera atachotsa zizindikiro za matendawa. Pseudomembranous colitis ndiye chifukwa chothana ndi maantibayotiki.
Mavuto ndi magwiridwe antchito a chiwindi michere amachepetsa nthawi ya maphunzirowa, amafunika kuwunika pafupipafupi.
Kuchita okakamizidwa diuresis kumathandizira kuti kuchotsedwa kwachangu kwa zinthu zogwira ntchito.
Siyani kumwa mankhwalawa ndikuchita mankhwalawa ndikofunikira kuti muthe kusintha kwa anaphylactic.
Kupezeka kwa matenda am'mimba thirakiti ndi kutsegula m'mimba, nseru, ndi kusanza ndizomwe zimapangitsa kuti pakhale mankhwala osokoneza bongo.
Kuyenderana ndi mowa
Simungathe kuphatikiza maantibayotiki ndi mowa. Mowa umalepheretsa zochita za michere. Kuchita kwa mowa ndi antibacterial wothandizila kumayambitsa zovuta zingapo, kumapangitsa kuledzera.
Zokhudza mphamvu pakuwongolera njira
Zizindikiro zamavuto amanjenje omwe amachitika chifukwa chomwa mankhwalawa zimapangitsa kuti zikhale zovuta kugwira ntchito yovuta, kuyendetsa galimoto. Chizungulire, kufooka, komanso kusintha kwa chikumbumtima kumasokoneza ntchito zomwe zimafunikira chidwi chochulukirapo.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Amangotchulidwa ndi dokotala wokhazikika, poganizira zoopsa zomwe zingachitike.
Alibe mphamvu teratogenic pa mwana wosabadwayo.
Ngati ndi kotheka, mlingo woyenera wovomerezeka umapangidwira nthawi yoyamba ya mimba. Kugwiritsanso ntchito mankhwalawa kumaloledwa malinga ndi malangizo.
Kuchotseredwa mkaka wa m'mawere si kuphwanya mankhwala pakukonzekera mkaka. Mkhalidwe wa mayi ndi mwana uyenera kuyang'aniridwa.
Maonekedwe obadwa kumene mwa zizindikiro za matenda am'mimba osokoneza, kukula kwa candidiasis kumafuna kuchotsedwa kwa mankhwalawa.
Flemoklav Solutab ndi okhawo omwe amapezeka ndi adokotala omwe amawaganizira zoopsa zomwe zingachitike, samapereka mphamvu kwa mwana wosabadwayo.
Momwe mungaperekere Flemoklav Solutab kwa ana
Mlingo ndi pafupipafupi kayendetsedwe ka ana zimatsimikiziridwa ndi zaka. Kuwerengera kumachitika pa kilogalamu imodzi ya kulemera kwa thupi patsiku.
Mapiritsi okhala ndi mankhwalawa omwe ali ndi osachepera mlingo wa mankhwalawa amaperekedwa kwa ana osakwana zaka 7. Ndi thupi lochepera makilogalamu 14, mankhwalawa satchulidwa chifukwa chosatheka kupanga dosing yolondola.
Ana opitirira zaka 7 amatha kumwa mankhwalawa olembedwa "422" kawiri pa tsiku. Ana osakwana zaka 12 amafunsidwa kuchepetsedwa.
Mlingo wa "424" umaperekedwa kwa mwana wachikulire wolemera bwino. Kuchulukitsidwa kovomerezeka kumaloledwa katatu pa tsiku.
Ndi thupi la mwana lochepera makilogalamu 14, mankhwalawa satchulidwa chifukwa chosatheka kudziwa dosing yolondola.
Popewa kukula kwa zosafunika pamatumbo, ndibwino kuti ana apereke mankhwala ndi chakudya.
Ngati ndi kotheka, mlingo umatha kuwirikiza kawiri, koma osapitirira 60 mg + 15 mg pa 1 kg wolemera patsiku.
Pafupipafupi wa makonzedwe, mlingo, kuwerengera kwa zoopsa zilizonse ziyenera kutsimikiziridwa ndi dokotala.
Simungasiye kumwa nokha, simungathe kuwonjezera nthawi ya chithandizo.
Mlingo wokalamba
Kugwiritsira ntchito mankhwala ophatikizidwa a gulu la penicillin popanda kusintha kwa zovomerezeka kwa okalamba.
Mchitidwe wa hepatobiliary umayankha motsatizana masabata angapo atatha kuthandizira. Zotsatira zosafunikira zoterezi zimachitika nthawi zambiri kukalamba. Vutoli likufunika kuonetsetsa kwakanthawi kochepa kwambiri ka mankhwala, osapereka mankhwala munthawi yomweyo.
Malangizo oletsa kukalamba amasungidwa kwa anthu omwe ali ndi vuto la impso.
Malangizo oletsa kukalamba amasungidwa kwa anthu omwe ali ndi vuto la impso. Mlingo wa 1000 mg sunagwiritsidwe ntchito kuchuluka kwa kusefera kwamagetsi osakwana 30 ml / min.
Bongo
Mankhwala osokoneza bongo amachititsa kuti pakhale zovuta zoyipa zoyipa. Maonekedwe akusanza, kutsegula m'mimba kumabweretsa kusowa kwamadzi, kusokonezeka kwa ma-electrolyte. Kusokonezeka kumayamba, chikhazikitso cha matenda.
Mankhwala osokoneza bongo amafunikira kuthetsedwera kwa mankhwala, kukonza kwambiri kwa kusokonezeka kwa elekitrodi, kutulutsa kogwiritsa ntchito thupi. Woopsa aimpso kulephera hemodialysis.
Kuchita ndi mankhwala ena
Kuphatikizika kwa glycosides kumabweretsa kuwonjezeka kwa ndende zawo m'magazi, kuwonjezereka kwa poizoni.
Osagwiritsa ntchito ndi disulfiram.
Zodabwitsazi zimadziwika ndi nthawi yomweyo ya bacteriostats yamagulu ena opanga mankhwala.
Flemoklav Solutab sangagwiritsidwe ntchito ndi Disulfiram.
Kuopsa kwa magazi kumakhalapo mukamagwiritsidwa ntchito limodzi ndi anticoagulants.
Kulandiridwa kwa Allopurinol kumayambitsa kupezeka kwa khungu.
Mankhwala osapatsirana omwe amaletsa kutupa amalepheretsa impso ya impso.
Makonzedwe a methotrexate omwewo amathandizira kuwonjezeka kwake.
Kuchita bwino kwa njira zakulera za mahomoni kumachepetsedwa tikamayikidwa limodzi ndi antibacterial.
Analogi
Ma Analogs a mankhwala oyambawo ali ndi zosakaniza zomwe zimagwira. Siyanani pamtengo, zokomera.
Malangizo oyenera ndi omwe amagwiritsidwa ntchito nthawi zambiri:
- Panklav;
- Flemoxin Solutab;
- Augmentin;
- Amoxicillin;
- Ecoclave;
- Amoxiclav.
Analogue yomwe imagwiritsidwa ntchito nthawi zambiri ya flexamine solutab ndi Augmentin.
Dokotala ayenera kusankha analogue chithandizo. Wopezeka mu mawonekedwe a kuyimitsidwa ndi ufa ndiwothandiza kugwiritsa ntchito ana.
Kupita kwina mankhwala
Yoperekedwa ndi mankhwala.
Mtengo Flemoklav Solyutab
Mtengo wake umatengera mlingo wa mankhwalawo. Mtengo wake umachokera ku 298 mpaka 468 rubles. kunyamula.
Flemoklav Solutab ya mankhwala
Sungani kutentha mpaka 25 + C pamalo osavomerezeka ndi ana.
Alumali moyo wa mankhwala
Zawonetsedwa pamaphukusi.
Kwa mankhwala olembedwa "425" ndi zaka ziwiri. Mapiritsi omwazika m'milingo yaying'ono amasungidwa kwa zaka zitatu.
Pambuyo pa kumaliza ntchito sikutha kugwiritsidwa ntchito.
Ndemanga za Flemoklava Solutab
Creola, wazaka 26, Moscow
Mankhwala ndi othandiza. Zotsatira zoyipa sizimayambitsa. Khosi langa limandipweteka kwakanthawi. Sinusitis yayamba. Dokotala adamuuza Flemoklav. Anatenga kawiri patsiku. Kusungunuka m'madzi. Pambuyo masiku 5, kuchira kunabwera.
Amita, wazaka 23, Moscow
Mwanayo anali ndi atitis yokhudzana ndi mbali ziwiri. Kutentha kwambiri. Dokotala adapereka mankhwalawa pa mlingo wa 250 mg + 62,5 mg. Otitis anachiritsa masiku 10. Panalibe zoyipa.
Vella, wazaka 31, Moscow
Mwana wanga wamkazi anali ndi zilonda zapakhosi. Amatenga monga adauzidwa ndi dokotala. Kubwezeretsa kunabwera m'masiku 6.
