Zotsatira za thrombo ACC mu shuga

Mankhwala omwe amayendetsa mamasukidwe a magazi amagawika m'magulu awiri: ma anticoagulants (owonda magazi) ndi ma antiplatelet agents (othandizira omwe amalepheretsa kuphatikiza kwa maselo am'magazi). Thrombo ACC ndi m'gulu lomaliza la mankhwalawa ndipo cholinga chake ndi kuthandiza odwala omwe ali ndi vuto la mafuta osokoneza bongo, shuga mellitus kapena kuthamanga kwa magazi.

Mayina apadziko lonse lapansi

Acetylsalicylic acid. Mu Latin - Acidum acetylsalicylicum.

Thrombo ACC idapangidwa kuti ichiritse odwala omwe ali ndi vuto la mafuta metabolism, shuga mellitus kapena kuthamanga kwa magazi.

ATX

B01AC06

Kutulutsa mafomu ndi kapangidwe kake

Mankhwala amapezeka mu mawonekedwe a kuzungulira kwa mapiritsi oyera a biconvex okhala ndi filimu. Gawo la mankhwalawa limakhala ndi 50 kapena 100 mg yogwira ntchito - acetylsalicylic acid. Monga zigawo zothandiza ndi:

• shuga mkaka;
• ma cellcose a microcrystalline;
• colloidal silicon dioxide;
• wowuma mbatata.

Kuphimba kwa enteric kumakhala ndi talc, ethyl acrylate Copolymer, triacetin ndi methaconic acid. Mapiritsi amapezeka m'matumba a blister a zidutswa 14 kapena 20. Mukatoni kamatakiti 14 a mankhwalawo ali ndi matuza awiri, magawo 20 - matuza 5.

Mankhwala amapezeka mu mawonekedwe a kuzungulira kwa mapiritsi a biconvex oyera.

Zotsatira za pharmacological

Acetylsalicylic acid (ASA) ili ndi chinthu chosunga ma antiplatelet chomwe chimalepheretsa kuphatikizika kwa magazi. Pulogalamu yogwira ntchito ili m'gulu la mankhwala omwe si a anti -idalidal anti-yotupa (NSAIDs), popeza kuti ndi omwe amachokera ku salicylic acid. Zotsatira zakuchizira zimachitika chifukwa cha kuponderezana kosasinthika kwa cycloo oxygenase. Enzyme ikakhala kuti ikulephera, kupanga kwa ma prostaglandins, thromboxane ndi uhule. Chifukwa cha kuponderezedwa kwa katulutsidwe a thromboxane A2, mapangidwe a maselo, kuphatikiza (kupondaponda) ndi kupendekera maselo.

Mphamvu ya antiplatelet imapitirira kwa sabata litatha kamodzi. Kukhalitsa kotere kwa acetylsalicylic acid kumagwiritsidwa ntchito pochiza komanso kupewa ischemic, matenda a varicose, kulowetsedwa kwa myocardial.

Pharmacokinetics

Pakaperekedwa pakamwa, acetylsalicylic acid imatenga mofulumira 100% m'matumbo aang'ono. Mapiritsi sasokoneza mucosa wam'mimba chifukwa cha mawonekedwe a filimu. Pa mayamwidwe, pang'ono kagayidwe kwa salicylic acid kumachitika. Mankhwala awa amasinthidwa m'chiwindi kupanga salicylates.

Ikalowa m'magazi, ASA imamanga ku 66-98% ndi mapuloteni a plasma ndipo imagawidwa mwachangu ku minofu. Kukopeka kwa Serum sikuchitika. Kutha kwa theka moyo kumafika mphindi 15-20. Njira ya kwamikodzo imangotulutsa 1% yokha ya mlingo wovomerezeka mu mawonekedwe ake oyambira. Zotsalira zimasiya thupi mu mawonekedwe a metabolites. Ndi mawonekedwe abwinobwino a nephrons, 80-100% ya mankhwalawa amathandizidwa kudzera mu impso kwa masiku 1-3.

Pakaperekedwa pakamwa, acetylsalicylic acid imatenga mofulumira 100% m'matumbo aang'ono.

Zizindikiro zogwiritsidwa ntchito

Mankhwalawa amathandizira kupewa matenda oopsa a m'matumbo a mtima pamene wodwala ali pachiwopsezo (kuthamanga kwa magazi, kunenepa kwambiri, msinkhu wokalamba kuposa zaka 50, zizolowezi zoipa, matenda a shuga. Mu zamtima, akatswiri azachipatala amayenera kupereka mankhwalawa potsatira zotsatirazi:

• Monga kupewa kupewa thromboembolism pambuyo zosokoneza zochitika ndi opaleshoni ntchito ziwiya: coronary artery bypass grafting, stenting, angioplasty;
• ndi mitsempha yakuya;
• kuchiritsa kupweteka kwa malungo chifukwa cha chimfine;
• kupewa kufalikira kwamkati muubongo;
• mankhwalawa a angina okhazikika ndi mtundu wosakhazikika;
• kuteteza chitukuko cha kubwereza kwa mtima;
• monga kupewa matenda a sitiroko, kuphatikiza pa zochitika za ubongo.

Mankhwalawa amagwiritsidwa ntchito kuti ateteze pulmonary embolism itatenga nthawi yayitali, yomwe imafunikira pakatha nthawi yothandizira.

Thrombo ACC imafotokozedwa ngati njira yoteteza matenda a thromboembolism.

Mankhwala amathandizidwa kuti apangidwe kwamitsempha.

Thrombo ACC nthawi zina imalembedwa kuti ipulumutse ululu panthawi ya malungo.

Mankhwala a Thrombo ACC amadziwika kuti aletse kufalikira kwakanthawi mu ubongo.

Zochizira khola losakhazikika ndi losakhazikika la angina pectoris, Trombo ACC ndi mankhwala.

Thrombotic ACC imatengedwa kuti alepheretse kubwerezanso kwa vuto la mtima.

Monga kupewa kukanika, pali chizolowezi kupatsa Thrombo ACC.

Contraindication

Mankhwala saloledwa kapena amaletsedwa kugwiritsidwa ntchito mu milandu yotsatirayi:

• kuchuluka kwa tiziwalo timene timakhala ndi acetylsalicylic acid ndi ma NSAID ena;
• kutaya magazi;
• lactase tsankho, malabsorption a monosaccharides;
• zilonda zam'mimba zotupa;
• hemorrhagic diathesis;
• kuphatikiza ndi methotrexate Mlingo wa 15 mg ndi ntchito imodzi pa sabata;
• kwambiri aimpso kapena kwa chiwindi kusakwanira;

Chida sichikulimbikitsidwa kuti chizigwiritsidwa ntchito kwa odwala omwe ali ndi vuto la mtima ndi kalasi la IV.

Ndi chisamaliro

Kusamala kumafunika munthawi ya mankhwala ochiritsira odwala omwe ali ndi matenda otsatirawa, mikhalidwe ndi ma pathologies:

• mphumu ya bronchial;
• gout
• zilonda zam'mimba ndi duodenum;
• matenda opumira kwambiri;
• impso ya creatinine chilolezo chochepera 30 ml / min;
• II trimester ya mimba;
• kukanika kwa chiwindi;
• esophagus Reflux esophagitis;
• hay fever;
• kuphatikiza painkillers, anti-yotupa, anti-rheumatic mankhwala.

Ndikulimbikitsidwa kukambirana ndi dokotala za kuthetsa mankhwalawa mankhwala asanapangidwe opareshoni.

Ndi zilonda zam'mimba, thrombo ACC iyenera kumwedwa mosamala.

Thrombotic ACC imatengedwa mosamala mu mphumu ya bronchial.

Matenda a kupuma kwamatenda a mawonekedwe akulu, mankhwalawa ayenera kumwedwa mosamala.

Reflux esophagitis ya esophagus - chizindikiritso chomwe thrombo ACC iyenera kumwedwa mosamala.

Chenjezo liyenera kugwiritsidwa ntchito pophatikiza ma painkiller, anti-kutupa, anti-rheumatic mankhwala ndi Thrombo ACC.

Momwe angatenge

Mapiritsiwo adapangira pakamwa. The achire zotsatira zimawonekera pokhapokha nthawi yayitali. Mlingo ndi nthawi yayitali ya chithandizo chimatsimikiziridwa ndi katswiri wa zamankhwala, yemwe amadalira machitidwe a wodwala (zaka, kulemera kwa thupi), mayeso a labotale komanso mayeso akuthupi. Kuchuluka kwa zovuta ndi mtundu wa matenda zimakhudza njira yochizira.

M'mawa kapena madzulo

Mukasankha kugwiritsa ntchito kamodzi patsiku, tikulimbikitsidwa kumwa mankhwalawa usiku musanagone. Mukamagwiritsa ntchito mapiritsi a 2 kapena kupitilira apo, ndikofunikira kuti muzisamala pakatikati pa Mlingo wa maola 12. Poterepa, munthu amamwa mankhwala m'mawa ndi madzulo.

Musanadye kapena musanadye

Ndi bwino kumwa mankhwalawa musanadye kuti muchepetse zilonda zam'mimba. Pankhaniyi, ndikofunikira kumwa mapiritsi ndi madzi ambiri.

Kumwa mankhwala a shuga

Cholesterol imayikidwa mu mawonekedwe amipanda yamafuta pamakoma amitsempha. Chifukwa chake, odwala matenda ashuga ali pachiwopsezo - kwa anthu omwe amakonda kupezeka ndi matenda amtima (kunenepa kwambiri, kusuta, kukalamba, matenda oopsa). Ndi matenda a shuga, 100 mg patsiku ndi mankhwala.

Ndi matenda a shuga, 100 mg patsiku ndi mankhwala.

Kutenga nthawi yayitali bwanji

Odwala omwe ali ndi vuto losagwirizana ndi mtima wamtima amalangizidwa kuti atenge antiplatelet othandizira pamoyo wonse. Mankhwalawa athandizira kuchepetsa ngozi ya magazi m'zipinda zamtima. Gulu ili la anthu limaphatikizapo anthu omwe akudwala matenda a mtima, coralillation, angina pectoris, mtima.

Odwala omwe ali ndi mitsempha ya varicose, amakonda kuchuluka kwa magazi, imwani mankhwalawo mkati mwa masabata 1-2 mpaka mapulogalamu okhomerera amatha.

Zotsatira zoyipa

Zotsatira zoyipa zikachitika, funsani dokotala wanu yemwe athetse mankhwalawa kapena kusintha mlingo wa tsiku ndi tsiku.

Matumbo

Kuchokera pamimba yogaya, mawonekedwe a mseru komanso kusanza. Nthawi zina, kumwa mankhwalawa kumabweretsa zilonda zam'mimba ndi duodenum, limodzi ndi magazi. Kusokonezeka kwa chiwindi chifukwa cha kuchuluka kwa ntchito za aminotransferases mu hepatocytes zalembedwa.

Kutenga Thrombo ACC kungayambitse kuchepa kwa maonedwe owoneka.

Lopirel imatha kupweteketsa mutu.

Chizungulire ndi mbali imodzi ya mankhwala Lopirel.

Mukutenga Thrombo ACC, kutulutsa magaziamu kumatha kuchitika.

Kutulutsa magazi muubongo ndi chimodzi mwanjira zoyipa za mankhwalawa.

Pa mankhwala ndi Lopirel, nseru ndi kusanza zitha kuchitika.

Hematopoietic ziwalo

Mawonetsero otsatirawa akuti.

• zotupa m'mimba;
• magazi mu kwamkodzo thirakiti;
• magazi m`kamwa;
• hemolytic anemia;
• epistaxis, magazi a postoperative.

Kukha magazi kwobisika kumayendera limodzi ndi cyanosis ndi asthenia.

Pakati mantha dongosolo

Kusokonezeka kochokera mu ubongo wamanjenje (tinnitus, chizungulire, kupweteka mutu, kutsika kwamaso komanso kumva) zitha kukhala zizindikilo za bongo.

Matupi omaliza

Ndi chidwi champhamvu cha zigawo zikuluzikulu za mankhwalawa, zotupa, kuyabwa, edema, Quincke, edema, anaphylactic, Rhinitis, bronchospasm, kutupa kwa mphuno ndi pharynx.

Chifukwa cha kutupa kwa chifuwa, gulu la ambulansi liyenera kutchedwa.

Malangizo apadera

The yogwira mankhwala otsika Mlingo angayambitse kumayambika kapena kuchuluka kwa gout pamaso pa chidwi, pamene pa mlingo waukulu hypoglycemic akhoza kuyamba. Katundu womaliza ayenera kukumbukiridwa ndi odwala omwe ali ndi matenda ashuga.

The yogwira mankhwala otsika Mlingo angayambitse isanayambike kapena kuchulukitsa kwa gout.

Acetylsalicylates amakhala ndi mphamvu yayitali yomwe imatha kwa masiku 6-7 pambuyo pa makonzedwe, zomwe zimapangitsa kuti magazi azituluka magazi nthawi zambiri. Popewa, mankhwalawa amathetsedwa sabata latha opaleshoni isanachitike.

Kuyenderana ndi mowa

Ethanol okhala ndi mowa kumawonjezera mwayi wa zotupa zam'mimba zowonongeka m'matumbo.

Zokhudza mphamvu pakuwongolera njira

Munthawi yamankhwala omwe mumalandira mankhwalawa, ndikofunikira kuti musayendetse kuyendetsa galimoto, kugwiritsa ntchito njira zovuta, komanso zochitika zina zomwe zimafuna kuti anthu aziganiza bwino komanso aziganiza mwachangu.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Chipangizocho chimalowa mosavuta mu zotchinga, ndichifukwa chake mu nthawi yayitali ya embryonic kukula kumatha kusokoneza kuyika kwa ziwalo zazikulu ndi machitidwe. Pobadwa, mwana amatha kukhala ndi vuto la mtima kapena mkamwa.

Mu trimester ya III, mankhwalawa amayamba kuchepetsedwa kubadwa ndipo amatha kuyambitsa kulowetsedwa kwamtundu wa mluza. Chifukwa chake, wothandizira antiplatelet amagwiritsidwa ntchito pokhapokha pangozi pamene chiwopsezo ku moyo wa amayi chikupita pachiwopsezo cha intrauterine pathologies mwana wosabadwayo.

Pakati trimester, kugwiritsa ntchito mankhwala osokoneza bongo osaposa 150 mg patsiku amaloledwa. Ndi chithandizo chakanthawi, tikulimbikitsidwa kuletsa kuyamwitsa.

Mu odwala okalamba omwe ali ndi zaka zopitilira 50, pamakhala chiopsezo cha bongo.

Kukhazikitsidwa kwa thrombo ACC kwa ana

Muubwana, ndizoletsedwa kugwiritsa ntchito mpaka zaka 18. Zotsalira zake ndi rickets ndi Kawasaki syndrome.

Gwiritsani ntchito mu ukalamba

Mu odwala okalamba omwe ali ndi zaka zopitilira 50, pamakhala chiopsezo cha bongo.

Bongo

Ndi kugwiritsa ntchito mankhwala molakwika, ndikotheka kukulitsa chithunzi cha matenda osokoneza bongo ofanana ndi zizindikiro za kuledzera kwambiri:

• mutu ndi chizungulire;
• kulira m'makutu;
• chisokonezo ndi kutayika kwa chikumbumtima;
• thukuta;
• kupuma kwambiri chifukwa cha kuchepa kwa magazi, edema ya m'mapapo;
• arrhasmia, hypotension, kumangidwa kwamtima;
• kuphwanya kagayidwe kamchere wamadzi;
• kutulutsa magazi m'mimba ;;
• kugona, chikomokere;
• chikomokere, minofu kukokana.

Pakakhala vuto la bongo, kugonekedwa kuchipatala mwachangu ndi mawonekedwe a m'mimba ndi adsorbent ndikofunikira. Kuchiza kumapangidwira kuti azisamalira ntchito zofunikira komanso kuthandizira acid-base, madzi-electrolyte bwino. Ndi mawonekedwe a mawonekedwe, mawonekedwe a chithandizo amachitika.

Pakakhala vuto la bongo, kugonekedwa kuchipatala mwachangu ndi chifuwa cham'mimba ndikofunikira.

Kuchita ndi mankhwala ena

Ndi munthawi yomweyo kugwiritsa ntchito acetylsalicylic acid ndi mankhwala ena, zotsatirazi zimatheka:

1. Kutsika kwa plasma ndende ya methotrexate chifukwa cha kuchoka kwa mapuloteni.
2. Kuchepa kwa magazi kumawonjezeka, synergism (kuchuluka kwachulukidwe ka mankhwala onse awiri) kumawonedwa ndikuphatikizidwa ndi anticoagulants, clopidogrel, othandizira a thrombolytic.
3. Mankhwala osokoneza bongo amatha kuchitika pakumwa mankhwala a Digoxin.
4. Kuopsa kwa valproic acid kumatheka chifukwa chakuchoka kwawo kumapuloteni.
5. Ibuprofen amachepetsa mphamvu yothandizira mankhwalawa, chifukwa ndiwotsutsana ndi mankhwala.

Kuphatikiza ndi glucocorticosteroids, kuwonjezeka kwa kuphipha kwa salicylates ndi kufooka kwa mphamvu ya antiplatelet kulembedwa.

Analogi

Ngati kuli koyenera kusiya mankhwalawo, dokotala ali ndi ufulu wopereka mankhwala ena mwanjira ina, monga:

• Cardiomagnyl;
• Kubwereranso
• Aspenorm;
• Thrombogard;
• Wopatsa Mulungu;
• Detralex

Cardiomagnyl amadziwika kuti ndi analogue ya mankhwala a Thrombo ACC.

Aspenorm nthawi zina imasankhidwa m'malo mwa Trombo ACC.

Supombogard nthawi zina imafotokozedwa m'malo mwa mankhwala a Thrombo ACC.

Nthawi zina m'malo mwa Trombo ACC, Detralex imasankhidwa.

Aspirin Cardio, yemwe amalowetsedwa mokwanira mthupi, amatchulidwa ndi fanizo la mankhwala omwe amagwira ntchito.

Aspirin Cardio, yemwe amalowetsedwa mokwanira mthupi, amatchulidwa ndi fanizo la mankhwala omwe amagwira ntchito.

Kupita kwina mankhwala

Mankhwalawa amagulitsidwa ku pharmacies popanda mankhwala.

Mtengo wa Thrombo ACC

Mtengo wapakati wamankhwala umasiyanasiyana kuchokera ku ruble 37 mpaka 160, kutengera kuchuluka kwa mapiritsi omwe amakhala pabokosi lamakalata.

Kusungidwa kwa mankhwala a Thrombo ACC

Zimafunikira kuti phukusi lizikhala louma, lopanda malire kuchokera pamalo owala mpaka kutentha +25 + C. Musalole kuti mankhwalawo agwere m'manja mwa ana.

Tsiku lotha ntchito

Zaka zitatu

Ndemanga za madotolo ndi odwala za Thrombo ACC

Evgeny Filippov, katswiri wa zamtima, Rostov-on-Don

Ndimapereka mankhwala a TromboAss pokhapokha mutayang'anitsitsa wodwala yemwe ali ndi vuto la kayendedwe ka magazi. Kuchita bwino kwa mankhwalawa kwatsimikizika pakukonzekera mayesero azachipatala. Machitidwe anga, ndikuwona kusinthika kwa thanzi la odwala atatha milungu iwiri ya 1-2. Sindikupangira kupangira wekha mankhwala.

Valery Krasnov, wazaka 56, Ryazan

Ndakhala ndikutenga TromboAss zaka 5, chifukwa othandizira amatchulidwa chifukwa cha matenda amitsempha. Asanayambe kumwa mapiritsiwo, opaleshoni yovala magazi idachitidwa kangapo. Pambuyo pakuonda magazi, zinthu zinayamba kuyenda bwino ndipo palibe njira zina zowonjezera zomwe zidachitidwa. Kutsatira malangizo ogwiritsa ntchito, sanazindikire zoyipa.

Maria Utkova, wazaka 34, Yekaterinburg

Pokhudzana ndi thrombosis ya zotupa m'mimba, ThromboAss adayikidwa pambuyo pa opaleshoni yochotsa magazi. Panalibe kukhathamiritsa kwa zotupa, komanso kupezeka kwa thrombosis. Ngakhale machitidwe asintha. Kungodyetsa mwana mkaka sikunaloledwa. Madotolo adati mankhwalawa amawonekera kudzera m'mitsempha ya mammary ndipo amatha kuvulaza thupi lomwe likukula.