Kuonetsetsa magwiridwe antchito a ziwalo zonse ndikukhala ndi ntchito yofunika, thupi limafunikira mphamvu, yomwe imapangidwa chifukwa chakuchepa kwa glucose omwe amalowa m'maselo.
Pancreas insulin imatsimikizira kusasinthika kwa kagayidwe kachakudya. Muzochitika pamene mahomoni amalephera kuzindikirika ndi maselo am'matumbo, amalankhula za insulin kukana.
Kodi kukana insulin ndi chiyani?
Timadzi timene timatulutsidwa ndimatenda timafalikira ndi magazi mthupi lonse ndikuwongolera kuyamwa kwa glucose m'matupi. Mothandizidwa ndi zinthu zosasangalatsa, metabolic syndrome yotchedwa insulin kukana imayamba, ndipo mapuloteni, carbohydrate ndi metabolism yamafuta amasokonezeka.
Maselo amasiya kuyankha mahomoni, kulowa kwa shuga m'maselo ndikovuta, ndipo amayamba kudziunjikira m'magazi. Kasitomala amayamba kupanga kuchuluka kwa mahomoni, koma kukana kwa ma insulin sikulola kuchita bwino ndipo zotsatira zake, kuchuluka kwa shuga m'magazi kumawonjezeka. Mapeto ake, izi zimatha kudwala matenda a mtima, hyperglycemia, komanso matenda a shuga.
Kukana kwa insulin kumatha kuchitika ku mahomoni achilengedwe omwe amapangidwa ndi kapamba komanso thupi kudzera mu jakisoni.
Limagwirira ndi zomwe zimayambitsa
Kukana kwa insulin sikuwonetsa zizindikiro zotchulidwa, ndizotheka kudziwa kuchepa kwa chidwi cham'magazi ku timadzi tokha ndi zotsatira za kusanthula. Omwe atengeka kwambiri ndi matenda oterewa ndi azimayi achikulire komanso amuna okulirapo kuposa zaka 30.
Zinthu zotsatirazi zimatha kupangitsa kuti insulin ikane:
- Zinthu zoyipa. Pa gawo la majini, jini imakhudzidwa yomwe imathandizira kukula kwa zovuta za metabolic.
- Kusintha kwa mahomoni. Ma mahomoni ena opangidwa ndi ziwalo zambiri za endocrine amatha kuponderezana ndi insulin.
- Mavuto Olakwika Thupi limatulutsa ma antibodies omwe amasokoneza ntchito ya mahomoni.
- Zoyipa komanso zopweteka.
- Kupsinjika kwanthawi yayitali.
- Pafupipafupi kwambiri mahomoni amabwera m'thupi.
- Kugwiritsa ntchito mankhwala ena a mahomoni.
- Kuphatikiza kwa masewera olimbitsa thupi osakwanira ndi zakudya zosayenera, zomwe zimakhala ndi mafuta ochulukirapo komanso zakudya zamafuta.
- Kupsinjika kwambiri komanso kunenepa kwambiri.
Zotsatirazi zingakhudzenso chidwi cha ma cell receptors:
- kubereka mwana;
- zaka;
- kuperewera kwa maselo chifukwa cha kuperewera kwa mpweya mu kugona (apnea);
- chikonga ndi mowa;
- matenda opatsirana;
- zakudya zanjala.
Mothandizidwa ndi zifukwa izi, mahomoni amasiya kugwira ntchito zake, ndipo kuphatikiza kwakanthawi kwa mahomoni ndi kapamba kumawonjezera kuchuluka kwake mthupi ndi kukula kwa hyperinsulinemia, yomwe imayambitsa matenda oopsa komanso kuwonda. Glucose, osazindikira maselo, akupitilira kudziunjikira m'magazi ndipo hyperglycemia imachitika. Izi ndi zizindikiro za mtundu 2 wa shuga.
Ubale ndi matenda a shuga
Matenda a shuga a Mtundu Wachiwiri ndi zotsatira, osati chifukwa cha insulin. Matendawa amakula mwa anthu athanzi kale, pazifukwa zina ma cell receptor sakhala omvera mahomoni.
Udindo waukulu wa insulin ndikuwonetsetsa kuti glucose amalowa m'thupi pambuyo pakulowetsa, komwe shuga amawonongeka ndipo mphamvu imatulutsidwa.
Ndi kukana, maselo samayankhanso zochita za timadzi timadzi ndi kusokoneza mayamwidwe. Poyankha, kapamba amawonjezera kupanga kwa mahomoni kuti agwiritse ntchito shuga wambiri.
Zonsezi zimachitika bola ngati chindacho chimatha kutulutsa mahomoni. Munthawi imeneyi, zambiri za insulin m'thupi zimasunga shuga pamlingo wovomerezeka. Kupanga kukayamba kuchepa, shuga amawonjezera mphamvu yake. Zotsatira zake, kuchuluka kwa shuga kumayamba kuwonedwa osati mutatha kudya, komanso pamimba yopanda kanthu. Umu ndi momwe matenda a shuga amakulira.
Kodi ndimatenda ati omwe kukana insulin kumabweretsa?
Kuphatikiza pa kukula kwa matenda a shuga a 2, kukana insulini kungayambitse kukhalanso kwa ma pathologies:
- Polycystic ovary. Matendawa amapezeka motsutsana ndi kusinthika kwa mahomoni azimayi amsinkhu wobala mwana ndipo amadziwika ndi kukula kwa tsitsi kumaso ndi thupi, kuwonda kwambiri komanso kusowa kapena kusasinthika kwa mkombowo mwezi uliwonse. Hyperandrogenism imalumikizidwa ndi polycystic ovary, chifukwa chomwe testosterone imayamba kupangidwa mwamphamvu mwa iwo, yomwe imalongosola kukula kwa ndevu ndi masharubu mwa akazi.
- Chiwindi chamafuta chimapangidwa chifukwa cha kusokonezeka kwa lipid metabolism, chifukwa chomwe mafuta ochulukirapo amasonkhana m'matumbo a chiwindi ndipo izi zimatha kubweretsa pa oncology kapena cirrhosis ya gland.
- Atherosulinosis wokwiyitsidwa ndi kuphwanya komweko kwa kagayidwe kachakudya, chifukwa chomwe cholesterol imakhazikika pazitseko zamitsempha yamagazi. Fomu la cholesterol, makhoma a zotengera amayamba kulimba, zomwe zimapangitsa kuti minyewa isamachepere komanso kutsika kwa magazi. Kusakwanira kwa magazi ku ziwalo kumathandizira kuti pakhale kufa ndi njala, ndipo motsutsana ndi izi, ischemia, stroko ndi mtima, angina pectoris angayambike. Kuphatikiza pa kukana insulini, kusintha kwa ma atherosselotic m'makoma amitsempha yamagazi kumatha kukhazikitsidwa ndimphamvu ya chibadwa chamkati, chizolowezi cha chikonga komanso matenda oopsa.
- Kukula anomalies. Insulin yowonjezera m'thupi imathandizira kukulitsa mafupa ndi minofu, zomwe zimawonetsedwa ndikukula kwachangu kwa ana ndikupanga mawonekedwe akuluakulu a nkhope.
- Acrochordon ndi zotupa za khungu pakhungu lomwe limapangidwa ndi benign polyps a thupi kapena la bulauni lakuda, likuwoneka pamwamba pa khungu.
- Black acanthosis ndi kusintha kwam'mbali pakhungu, komwe kumadziwika ndi mawonekedwe akuda amtundu wakhungu kumapeto, kupindika komanso m'khosi.
Diagnostic diagnostic
Kuphwanya kwa kagayidwe kazakudya nthawi zambiri kumasonyezedwa ndikudzaza kwambiri m'chiuno ndi m'chiuno.
Mutha kuyeserera mwaulere kuyeserera kozungulira pamimba ndi m'chiuno pogwiritsa ntchito tepi ya sentimita.
Kenako muyenera kuchotsa m'mimba mwake m'chiuno kuchokera m'mimba mwake. Kusiyana kwa amuna sikuyenera kupitirira 1, mwa akazi 1.5-2.
Ngati Zizindikiro zikupitilira malire ovomerezeka, ndiye kuti izi zikuwonetsa kukhalapo kwa kulemera kwambiri ndipo, monga chotulukapo chake, chiopsezo chotenga insulin.
Pozindikira matendawa, dotolo amayang'anira wodwalayo, amayeza kukakamiza, amatenga chidziwitso cha zomwe akuwonetsa, momwe amakhalira ndi zomwe wodwala ali nazo, kupezeka kwa matenda opatsirana komanso kuthekera kwa cholowa chamtundu wa matenda.
Mtsogolomo, maphunziro azidziwitso amtundu wa mankhwala amaperekedwa:
- kuwerengetsa kuchuluka kwa thupi;
- magazi kuyesa kwa insulin kukana ndi zamankhwala amuzolengedwa;
- electrocardiogram;
- Ultrasound
Chizindikiro chachikulu ndicho kuyesa kwa magazi kwa insulin. Phunziroli limachitika pambuyo pa kusala kudya kwa maola 12, potenga zitsanzo zamagazi kuchokera kumapewa. Zinthu zovomerezeka zamafuta ndi 4-28 mcU / ml. Zizindikiro zowonjezereka zikuwonetsa kukula kwa hyperinsulinemia ndipo kumakupatsani mwayi wofufuza insulin.
Kuchiza matenda
Tsoka ilo, njira zabwino zochizira matenda sizinapangidwebe. Ndikotheka kusungitsa kuchuluka kwa mahomoni mkati mwa mtundu wokhawo wokhawo pokhapokha pakuchepetsa kufunikira kwa mahomoni kapena kuwonjezera chiwopsezo cha maselo kwa icho.
Pakukonzanso mankhwala, zakudya zamafuta zimagwiritsidwa ntchito ndi kuchepa kwa kuchuluka kwa chakudya chamafuta ambiri, kuwonjezeka kwa zochitika zolimbitsa thupi, komanso kugwiritsa ntchito mankhwala omwe amakhudza ma cell receptors.
Zakudya
Insulin yowonjezera imapangidwa poyankha kuthamanga kwa shuga. Chifukwa chake mumafunikira shuga pang'ono ndi chakudya. Ichi ndiye maziko a chakudya chokhala ndi mahomoni.
Ndikulimbikitsidwa kupatula chakudya cham'mimba chambiri chomwe chili ndi GI yayikulu (glycemic index) muzakudya, izi:
- zopangidwa ndi ufa wa tirigu;
- shuga ndi zinthu zomwe zili nazo;
- mbatata, mpunga ndi chimanga;
- Pasitala
- zakudya zamafuta ndi mchere;
- masoseji ndi marinade;
- msuzi wotentha ndi zonunkhira;
- zakumwa za gasi ndi khofi wamphamvu.
Makinawa azikhala ndi zinthu zotsatirazi:
- mbewu zonse kapena ufa wa rye;
- nsomba zodzaza ndi mafuta achilengedwe athanzi (nsomba, mackerel, hering'i);
- nsomba zam'madzi zam'madzi ndi nyama zam'madzi (kelp, seaweed, mussels, squid);
- nyama zamafuta ochepa (ng'ombe, nyama yamwana wamchere, nkhuku yoyera, nkhuku, kalulu);
- masamba omwe anali ndi CHIKWANGWANI komanso zipatso zopanda zipatso ndi ma peel (maapulo, kabichi, nkhaka, mapeyala, zukini);
- nyemba ndi mpunga wa bulauni;
- Buckwheat ndi oatmeal;
- zitsamba zatsopano ndi masamba a saladi;
- mkaka ndi mkaka wopanda mkaka wokhala ndi mafuta ochepa;
- walnuts ndi amondi;
- amaloledwa kudya dzira yophika ndi chidutswa cha chokoleti chakuda kawiri pa sabata.
Kanema pa zakudya zotsika kwambiri zamatenda a 2 shuga:
Pazakudya zolemetsa, zomwe ndiye mfundo yayikulu yokonza makhonzedwe awa:
- Zakudya siziyenera kukhala zopatsa mphamvu kwambiri, chifukwa chake ndibwino kusenda kapena chakudya chamasamba. Mutha kuphika kawiri pa sabata ndikuchotsa kwathunthu kukazinga mafuta.
- Ndikofunikira kwambiri kuti madzi azikhala osamala. Kuti muchite izi, muyenera kumwa 1.5-2 malita a madzi tsiku lililonse.
- Osatalikirana kwambiri pakudya. Idyani zabwinobwino pafupipafupi, koma pang'ono.
- Simungadye musanakagone, koma simungafe ndi njala.
Popeza kukana insulini sikungachiritsike, muyenera kutsatira mfundo za zakudya zoyenera pamoyo wanu wonse.
Mankhwala
Mwa mankhwala kuti abwezeretse chidwi cha ma cell receptors, adalembedwa:
- Metformin. Awa ndi mankhwala okhawo ovomerezeka ngati choletsa kupewa matenda a shuga 2. Ndi kutsatira mosamalitsa mlingo, Metformin imakulitsa chiwopsezo cha ma cellular receptor kuma cell a pancreatic, omwe amachepetsa kuchuluka kwa shuga m'magazi ndikulepheretsa kuchuluka kwa insulin.
- Acarbose Imatha kuletsa kuwonongeka kwa chakudya chamagulu, zomwe zimalepheretsa kukula kwa glucose mutatha kudya. Zotsatira zake, insulin yochepa ndiyofunikira.
Mankhwala osokoneza bongo monga troglitazone ndi rosiglitazone, omwe amakhudza maselo a maselo, saikidwanso kwa odwala omwe ali ndi insulin chifukwa cha zovuta pa chiwindi.
Zotsogola ndi kupewa
Kukana kwa insulin sikuchiritsidwa kwathunthu ndipo kumatha kupitilira pakapita nthawi. Kuperewera kwa mankhwalawa okwanira chifukwa cha kusintha kwa moyo komanso kusintha kwa zakudya, komanso kumwa mankhwalawa, kumabweretsa chitukuko cha matenda a shuga 2.
Matendawa amatha kupweteketsa mtima ndi ziwalo zamagulu am'mimba, ma pathologies am'mimba komanso kubereka, ndipo zimayambitsa kuphwanyidwa kwa kapangidwe kake ka minofu ndi mafupa. Matenda osalamulirika angakhudze chiyembekezo cha moyo komanso kupha.
Monga prophylaxis ya insulin kukana, tikulimbikitsidwa:
- kuwongolera kunenepa, kuletsa kukula kwa kunenepa;
- kutsatira mfundo za zakudya zoyenera;
- kusiya kusuta fodya ndi mowa;
- gawani nthawi yokhala ndi masewera komanso kuyenda;
- Osamamwa mankhwala popanda kuuzidwa ndi dokotala.
Kukwaniritsidwa kwa njira zodzitetezera kuphatikiza kuyezetsa kwapachaka ndikutsatira malingaliro onse omwe dokotala amakupatsani kuti muwongolere kuchuluka kwa insulin ndi shuga mthupi.