Rinsulin R ndi Rinsulin NPH - malangizo ogwiritsira ntchito

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Gawo lalikulu la chithandizo cha matenda a shuga ndikuwongolera kuchuluka kwa shuga m'magazi a wodwala. Kusinthasintha kwakuthwa kwa chizindikiro ichi ndi zovuta zowopsa komanso zizindikiro zazikulu.

Kuti mupewe, mankhwalawa omwe ali ndi insulin amagwiritsidwa ntchito nthawi zambiri. Zina mwa izi ndi mankhwala a Rinsulin R. Odwala ayenera kudziwa momwe imagwirira ntchito kuti igwiritsidwe ntchito moyenera.

Kupanga ndi mawonekedwe a kumasulidwa

Mankhwalawa amatanthauza mankhwala omwe amagulitsidwa ndi mankhwala, chifukwa kugwiritsa ntchito mosalamulirika kungavulaze thupi.

Ndi yankho la jakisoni, chinthu chachikulu chomwe ndi insulin yaumunthu, chopangidwa pogwiritsa ntchito tekinoloje ya DNA.

Zothandiza pa mankhwalawa ndi:

  • glycerol;
  • metacresol;
  • madzi.

Kutulutsidwa kwa Rinsulin kumachitika ku Russia. Njira yothetsera vutoli ndi yowonekera ndipo ilibe mtundu. Amayikidwa m'mabotolo agalasi a 10 ml.

Makhalidwe a pharmacological

Mankhwala amadziwika ndi zotsatira za hypoglycemic. Kutsika kwa shuga m'magazi kumachitika chifukwa cha zomwe zimapangitsa. Insulin, yomwe ilowa m'thupi la wodwalayo, imapangitsa kuti glucose ayambe kugwira ntchito yake ndikugawa maselo. Rinsulin amachepetsa nawonso shuga.

Chida ichi chili ndi nthawi yayitali yochitapo kanthu. Zimayamba kukhudza thupi theka la ola pambuyo pobayira. Imagwira kwambiri pakati pa maola 1-3 mutatha kugwiritsa ntchito. Mphamvu yake imatha patatha maola 8.

Kuchita bwino komanso nthawi yayitali ya Rinsulin zimatengera Mlingo ndi njira yoyendetsera. Kuchotsa izi m'thupi kumachitika ndi impso.

Malangizo ogwiritsira ntchito

Tikulimbikitsidwa kugwiritsa ntchito mankhwalawa mtundu 1 komanso matenda a shuga 2 ngati sizotheka kutulutsa shuga ndi mankhwala a pakamwa. Rinsulin ndi jekeseni yomwe imatha kuchitidwa intramuscularly, subcutaneally and intravenous. Njira yoyenera kwambiri yogwiritsira ntchito imatsimikiziridwa payekhapayekha.

Mlingo wa mankhwalawa amawerengedwa potengera mawonekedwe azachipatala. Nthawi zambiri, 0,5-1 IU / kg ya kulemera kwa odwala amayenera kuperekedwa tsiku lililonse.

Mankhwalawa amaloledwa kugwiritsidwa ntchito limodzi ndi mankhwala ena a hypoglycemic, ngati pakufunika.

Nthawi zambiri, rinsulin imayang'aniridwa mosavuta. Zingwe ziyenera kuperekedwa kwa ntchafu, phewa, kapena khomo lam'mimba lakunja. Ndikofunikira kusinthana mawebusayiti enanso, momwe mungadziwire lipodystrophy.

Intramuscular makonzedwe amachitika kokha malinga ndi dokotala. Mitsempha, mankhwalawa amatha kuperekedwa ndi othandizira azaumoyo. Izi zimachitidwa m'njira zovuta.

Phunziro la kanema pakukhazikitsa insulin pogwiritsa ntchito cholembera:

Zotsatira zoyipa

Kumwa mankhwala aliwonse kungayambitse zovuta zina. Kuti mudziwe zovuta zomwe Rinsulin imayambitsa, muyenera kuphunzira malangizo ndi kuwunika pamabungwe kuchokera kwa odwala.

Nthawi zambiri ndi kugwiritsidwa ntchito kwake, zotsutsana zotsatirazi zimachitika:

  • hypoglycemic state (imayendera limodzi ndi zizindikiro zambiri zosasangalatsa, monga chizungulire, kufooka, nseru, tachycardia, chisokonezo, ndi zina zambiri);
  • ziwengo (zotupa pakhungu, mantha anaphylactic, edema ya Quincke);
  • kuwonongeka kwamawonekedwe;
  • redness la pakhungu;
  • kuyabwa

Nthawi zambiri, mavuto amayamba kugwiritsa ntchito mankhwalawa ngakhale osagwirizana ndi kapangidwe kake. Kuti muthane ndi zovuta izi, muyenera kulumikizana ndi katswiri. Zotsatira zina zoyipa zimatha mukangomwa kumwa; ena amafunikira chithandizo chamankhwala.

Nthawi zina kuwonekera kwa matenda kumapangitsa kuti wodwalayo asokonezeke, kenako amafunika kulandira chithandizo chachikulu kuchipatala.

Kuyanjana kwa mankhwala osokoneza bongo

Rinsulin nthawi zina amagwiritsidwa ntchito popanga zinthu zovuta, koma amayenera kukhala mwadongosolo. Pali magulu a mankhwalawa chifukwa chomwe chidwi cha thupi pakupanga insulini chimakulitsidwa kapena kufooka. Muzochitika izi, ndikofunikira kusintha kuchuluka kwa mankhwalawa.

Iyenera kuchepetsa gawo la Rinsulin pomwe mukuigwiritsa ntchito motere:

  • mankhwala a hypoglycemic;
  • salicylates;
  • beta-blockers;
  • MAO ndi ACE zoletsa;
  • tetracyclines;
  • mankhwala antifungal.

Kuchita bwino kwa Rinsulin kumachepa ngati kugwiritsidwa ntchito limodzi ndi mankhwala monga:

  • okodzetsa;
  • antidepressants;
  • mankhwala a mahomoni.

Ngati pakufunika kugwiritsa ntchito nthawi yomweyo Rinsulin ndi mankhwalawa, Mlingo uyenera kuchuluka.

Osasintha mosaganizira dongosolo la mankhwalawa. Ngati gawo lalikulu la insulin likulowa m'thupi, mankhwala osokoneza bongo amatha kuchitika, chiwonetsero chachikulu chomwe ndi hypoglycemia. Ngati mumagwiritsa ntchito mlingo wochepa wa mankhwalawo, chithandizo sichingathandize.

Malangizo apadera

Njira zapadera za kumwa mankhwala nthawi zambiri zimaperekedwa kwa ana, amayi oyembekezera komanso okalamba.

Kuchiza ndi Rinsulin kumatanthauza kutsatira malamulo otsatirawa:

  1. Amayi oyembekezera. Palibe chifukwa chosinthira kuchuluka kwa mankhwalawa, chifukwa zomwe zimagwira sizikhudza mayiyo. Koma nthawi yomweyo, ndikofunikira kuwongolera msanga wamagazi a mkazi, chifukwa chizindikiro ichi chimatha kusintha mwana akabadwa.
  2. Amayi oyamwitsa. Insulin siyidutsa mkaka wa m'mawere, motero, sichikhudza mwana. Chifukwa chake, simukuyenera kusintha mlingo. Koma mayi akuyenera kuwunika zakudya zake, kutsatira malangizo ake.
  3. Anthu okalamba. Chifukwa chakusintha kokhudzana ndi ukalamba, matupi awo amatha kutengeka ndizovuta zamankhwala. Izi zimafuna kupenda wodwalayo ndikuwerengera Mlingo wosankhidwa asanafike Rinsulin.
  4. Ana. Amaloledwa kulandira mankhwala ndi mankhwalawa, koma moyang'aniridwa ndi katswiri. Mlingowo umaperekedwa palokha.

Malangizo apadera amaperekedwanso kwa odwala omwe ali ndi matenda a chiwindi ndi impso. Mankhwalawa amakhudza chiwindi, ndipo impso zimathandizira kuchotsa mankhwalawa m'thupi. Ngati pali zovuta ndi ziwalo izi, mlingo wa Rinsulin uyenera kuchepetsedwa kuti musayambitse hypoglycemia.

Analogi

Ngati pali tsankho kwa wothandizila wodwalayo, ndikofunika kusintha m'malo mwake ndi linanso. Dokotala angakuthandizeni kusankha.

Nthawi zambiri, cholowa m'malo chimalembedwa:

  1. Khalid. Maziko a mankhwalawa ndi insulin yaumunthu. Amapezeka mu mawonekedwe a yankho la jekeseni, omwe amachitika kudzera m'mitsempha ndi subcutaneous.
  2. Gensulin. Mankhwalawa amatha kukhala amitundu iwiri: Gensulin N (yankho lautali wa jekeseni) ndi Gensulin M30 (kuyimitsidwa pang'ono). Tulutsani m'mabotolo amagalasi mumakatoni.
  3. Protafan. Maziko a chida ichi ndi insulin isophan. Protafan imazindikira mwa kuyimitsidwa, komwe kumadziwika ndi nthawi yayitali yochitapo kanthu.
  4. Tidzatero. Mankhwalawa ali ndi zochitika zazifupi. Vozulim ilipo mu njira yothetsera jakisoni, chinthu chachikulu chomwe ndi insulin yaumunthu.
  5. Biosulin. Amakhala mu mawonekedwe a kuyimitsidwa ndi yankho. Mankhwalawa amathandizira kuyamwa kwa shuga m'thupi, zomwe zimathandiza kuchepetsa kuchuluka kwake m'magazi.
  6. Gansulin. Imayikidwa ngati kuyimitsidwa komwe chinthu chogwira ntchito ndi insulin isophan. Mukamagwiritsa ntchito, muyenera kutsatira malangizo ndikumvera zomwe zingachitike.
  7. Humulin. Mankhwalawa amachokera ku insulin ya anthu ndipo amawoneka ngati kuyimitsidwa. Jekeseni wothandizirana ndi mankhwalawa amathandizira kuti magazi asungunuke. Ndi zoletsedwa kugwiritsa ntchito ndi hypoglycemia komanso tsankho pazigawo zake.
  8. Rosinsulin. Chida ichi chimagulitsidwa ngati yankho la jakisoni. Amayikidwa m'makalata atatu a 3 ml. Chofunikira chake chachikulu ndi insulin yaumunthu.
  9. Insuran. Mankhwalawa ndi kuyimitsidwa komwe kumagwiritsidwa ntchito poyambira. Zimasiyanasiyana pakatikati pochitika. Wopangidwa ndi Insuran kutengera isophan insulin.

Mankhwalawa amadziwika ndi zotsatira zofanana, koma ali ndi kusiyana komwe kumayenera kuganiziridwa. Muyeneranso kudziwa momwe mungasinthire molondola kuchokera ku mankhwala ena kupita ku wina.

Rinsulin NPH

Mankhwalawa amafanana kwambiri ndi Rinsulin R. Muli ndi isofan insulin. Mankhwalawa amakhala ndi nthawi yayitali ndipo amayimitsa jakisoni.

Amagwiritsidwa ntchito pokhapokha, omwe amathandizira kupanga cholembera cha Rinsulin NPH.

Ndikofunikira kukhazikitsa mankhwalawa m'mimba khoma, ntchafu kapena phewa. Kuti zinthu zamankhwala zimidwe mosavuta, jakisoni amayenera kupangidwa m'magawo osiyanasiyana a thupi mkati mwa gawo lomwe linanenedwa.

Zothandiza zotsatirazi ndi gawo la Rinsulin NPH:

  • phenol;
  • glycerin;
  • protamine sulfate;
  • sodium hydrogen phosphate;
  • metacresol;
  • madzi.

Mankhwalawa amamasulidwa m'mabotolo agalasi 10 ml. Kuyimitsidwa ndi koyera;

Mankhwalawa amagwira ntchito mofanananira ndi Rinsulin R. Amalimbikitsa kuthamanga kwa shuga ndi maselo ndikuchepetsa kupanga kwake ndi chiwindi. Kusiyanako kukugona pakukhalitsa kwakutali - kumatha kufikira maola 24.

Mtengo wa Rinsulin NPH umasinthasintha kuzungulira ma ruble 1100.

Mutha kudziwa kuti mankhwalawa ndi othandiza bwanji popenda ndemanga za wodwala za Rinsulin P ndi NPH. Amasiyana. Odwala ambiri amalabadira mankhwalawa, koma pali ena omwe chithandizo chotere sichinawakomere. Kusakhutira kumachitika chifukwa cha zotsatira zoyipa zomwe zingayambitse mankhwala okhala ndi insulin.

Nthawi zambiri, zovuta zinkachitika mwa anthu odwala matenda ashuga omwe sanatsatire malangizo kapena kwa iwo omwe thupi lawo linali logontha. Izi zikutanthauza kuti mphamvu ya mankhwalawa imatengera zochitika zambiri.

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