Mu pulogalamu "Live Healthy" Elena Malysheva adatinso kuti metformin imatalikitsa moyo.
Kodi izi zilidi choncho?
Choyamba muyenera kudziwa kuti ndi mtundu wanji wa mankhwalawo, mphamvu zake ndi chifukwa chake amagwiritsidwa ntchito.
Kodi metformin ndi chiyani?
Metformin ndi piritsi lomwe limagwiritsidwa ntchito pa matenda a shuga a 2. Ndilo gulu la Biguanides. Ndi imodzi mwakale kwambiri komanso imodzi mwa mankhwala othandiza kwambiri omwe agwiritsidwa ntchito pochiza matendawa. Kuchokera ku kalasi ya biguanides, awa ndi mankhwala okhawo omwe samakhudza odwala omwe ali ndi vuto la mtima. WHO adaziyika pamndandanda wazithandizo zofunika kwambiri.
Metformin ndi dzina la generic genant mankhwala. Mayina amalonda awa akuwonetsedwa pamsika wa pharmacological: Glucofage, Glycomet, Bagomet, Diaformin, Insufor, Langerin, Meglifort, Metamine, Metfogamma, Metformin Sandoz, Metformin-Teva, Panfor Sr, Siofor, Zukronorm.
Kwa nthawi yayitali, mankhwalawa anali kugwiritsidwa ntchito kokha pochiza matenda ashuga. Pambuyo pazakafukufuku wazaka zambiri, zidapezeka kuti zimachepetsa mafuta. Pamaso pa prediabetes, itha kugwiritsidwa ntchito kuchepetsa mwayi wokhala ndi matendawa. Amagwiritsidwanso ntchito ngati thumba losunga mazira la polycystic ndi ma pathologies ena angapo omwe kukana insulini ndikofunikira.
Ubwino wa metformin umawonedwa:
- ndi matenda ashuga;
- ndi kagayidwe kachakudya matenda;
- popewa matenda amtima;
- popewa khansa.
Mphamvu yovuta ya mankhwalawa polimbana ndi ukalamba imatsimikiziridwa. Kufunika kofunikira - kutsitsa chitseko chaimfa kuchokera ku zovuta zamtima. Zimatsimikizidwanso kuti zimachepetsa chiopsezo chokhala ndi oncology mwa odwala matenda a shuga, metabolic syndrome. Kukana kwa mahormoni ndi imodzi mwamaopsezo opanga zotupa. Insulin imathandizira kukula kwa minofu, kuphatikiza osati yabwino kwambiri.
Kodi mankhwalawa amagwira ntchito bwanji?
Mankhwalawa amachepetsa kuchuluka kwa shuga m'magazi ndi kaphatikizidwe ka shuga m'chiwindi. Kuphatikiza pa zotsatira za hypoglycemic, zimakhudza zovuta za lipid. Lowers triglycerides ndi cholesterol yoyipa (LDL). Ndiwokhawo mankhwala, malinga ndi maphunziro, omwe amachepetsa kuchuluka kwa matenda a mtima ndi stroko.
Chimodzi mwazabwino za mankhwalawa ndikuti samachulukitsa thupi poyerekeza ndi mankhwala ena a hypoglycemic. Kwa odwala matenda ashuga, amathandiza kutalikitsa komanso kukhala ndi moyo komanso kukhala wapamwamba. Zochita zake zimapangidwa kuti muchepetse kunenepa. Amawonetsera kunenepa, ngati chithandizo cha zakudya sichinabweretse zotsatira zoyenera.
Mankhwalawa amachepetsa kudya komanso kuyamwa kwa shuga m'mimba. Kutsegula kwa insulin sikumachitika, zotsatira za hypoglycemic zimachitika mwa kusintha kukhudzidwa kwa mahomoni ndi kuphatikizira kwakukulu kwa shuga. Chifukwa chomwa mankhwalawa, njira zamatenda zomwe zimayamba motsutsana ndi maziko a matendawa zimayamba kuchepa. Itha kugwiritsidwa ntchito ma pathologies omwe amawonetsa insulin kukana. Kuchita bwino kwa mankhwalawa kumawonetsedwa m'mimba lama polycystic, prediabetes, matenda ena a chiwindi, komanso kunenepa kwambiri.
Metformin imachepetsa kaphatikizidwe kagayidwe kachakudya ka chiwindi ndikuwonjezera kaphatikizidwe ka glycogen. Mothandizidwa ndi mankhwalawa, magazi mu chiwindi amachitidwa, mulingo wa triglycerides ndi cholesterol amachepetsa. Kutenga kwa glucose minofu, wogwiritsa ntchito mphamvu zazikulu, kumathandizidwa. Kuchulukitsidwa kwa shuga wokonzedwa kumafotokozedwa ndikuti ndikosavuta kulowa minofu.
Zotsatira za kumwa mankhwalawa:
- kuchepetsa shuga;
- Kuchepetsa kufunika kwa amkati insulin;
- kutsekeka kwa insulin kukana;
- Kuchepetsa kupita patsogolo kapena kukula kwa atherosulinosis;
- kuchepa kwa triglycerides ndi LDL;
- kutsika kwa kupanikizika, kuchepa kwa shuga wa mapuloteni;
- kutsekereza ma enzyme omwe amawononga maselo;
- kuteteza mtima.
Contraindication
Mwa contraindication ntchito:
- kukanika kwa impso;
- Hypersensitivity mankhwala;
- matenda opatsirana pachimake;
- ketoacidosis;
- kukanika kwa chiwindi;
- vuto la mtima;
- isanayambe komanso itatha mayeso a radiographic ndikuyambitsa kusiyana;
- isanachitike kapena itatha ma opaleshoni;
- ukalamba;
- malabsorption B12.
Chithandizo cha matenda ashuga
M'mbuyomu, Metformin idagwiritsidwa ntchito kokha pochiza matenda ashuga. Kafukufukuyu adawonetsa kuti mankhwalawa akuwonetsa katundu wina. Amagwiritsidwa ntchito ngati thumba losunga mazira la polycystic, kunenepa kwambiri, komanso kupewa matenda ashuga.
Komabe, cholinga chachikulu cha metformin ndicho chithandizo cha matenda a shuga amitundu iwiri. Amachepetsa shuga komanso gluconeogenesis, amachepetsa triglycerides ndi LDL, ndipo amachepetsa chilakolako chofuna kudya. Kuchepa kwa glucose kumachitika pamimba yopanda kanthu ndikatha kudya. Minofu minofu imalandira shuga wambiri chifukwa cha kuwonjezeka kwa kumwa kwake. Kuyamwa kwa shuga m'matumbo amachepetsa.
Mankhwalawa samalimbikitsa kupanga mahomoni. Kuchepetsa mphamvu ya shuga kumachitika mwa kukonza mayamwidwe a shuga ndi minofu. Panthawi ya chithandizo ndi Metformin, kufunika kwa insulin kumachepetsedwa. Chidachi chimachepetsa kuopsa kwa zovuta ndi kufa ndi 35% poyerekeza ndi mankhwala ena a hypoglycemic ndi insulin.
Mulingo wokwezeka wamafuta nthawi zonse umakhala wowopsa pamtima. Mtundu wa mawonekedwe a scum pamakoma a zotengera, ma microcirculation amasokonekera. Kuchokera pano pali zotupa za m'maso, mitsempha yamagazi ya muubongo ndi mtima, ziwiya zamiyendo ndi zina zotero.
Mukamamwa mankhwalawo, mphamvu ya hypoglycemic imawonedwa. Kutengera ndi kuchuluka kwa shuga ndikuletsa glycemia, wodwalayo angafunenso kumwa chinthu china. Koma atalemba mankhwalawo, ndizotheka kuchepetsa kuopsa kwa matenda amtima ndi gawo limodzi.
Metformin sikumatsogolera pakukula kwa hypoglycemia ikatengedwa molondola. Amawonedwa kawirikawiri ndi zolimbitsa thupi kapena kugwiritsa ntchito mankhwalawo ndi othandizira ena a hypoglycemic. Mwa odwala athanzi, samachepetsa shuga.
Kukalamba
Monga tafotokozera pamwambapa, Elena Malysheva adati mu pulogalamu yake kuti Metformin imalepheretsa ukalamba. Adanenanso za kuthekera kokulitsa moyo wathunthu komanso wapamwamba. Tsopano mwatsatanetsatane wazambiri.
"Ukalamba" ndi lingaliro lophiphiritsa. Kutanthauza kukalamba msanga chifukwa cha matenda. Mwanjira ina, uwu ndi m'badwo wachilengedwe wa thupi, womwe sugwirizana ndi chizindikirochi.
Pa pulogalamu "Live Healthy", adayikamo dongosolo la masikelo amagetsi, omwe amayeza zaka zaka.
Chinsinsi cha kukalamba kotereku ndi kuchuluka kwa glucose m'magazi. Zotsatira zake, mapuloteni amaswedwa (izi zimaphatikizapo mapuloteni amkhungu), zomwe zimatsogolera pakupanga makwinya. Ming'alu mawonekedwe mu ziwiya motsogozedwa ndi shuga wowonjezera.
Kuchokera mu molekyu yoyamba ya glucose, mamolekyulu a 2 a triglyceride amapezeka, i.e. mafuta. Mafuta amadziunjikira muming'alu, ndikupanga zomwe zimatchedwa atherosranceotic malo. Mankhwala amapangidwa kuti aletse njirazi zomwe zimachitika m'matumbo.
M'zaka zonse zapitazi, maphunziro osiyanasiyana a mankhwala akhala akuchita. Kumapeto kwa chaka cha 2015, kafukufuku wasayansi (wazaka 25) wa Metformin ku University of England adamalizidwa.
Ophunzirawo anali anthu omwe anali ndi matenda ashuga amitundu iwiri. Malinga ndi zoneneratu, anali ndi zaka 8 zokha zokhala ndi moyo. Koma palibe amene anamwalira pa kuyesayesaku. Anazindikira kuti mankhwalawo amakankhira mwachindunji kuyamba kwa kufa ndi ukalamba.
Vidiyo yomwe inakambidwa ndi Dr. Malysheva wokhudza Metformin:
Zokhudza thupi
Metformin sichimakhudza kulemera kwakukulu poyerekeza ndi sulfonylureas. M'malo mwake, amagwiritsidwa ntchito mu zovuta kuchitira kunenepa. Zinapezeka kuti mankhwalawa amachepetsa mafuta.
Anthu athanzi omwe ali ndi shuga athanzi omwe akufuna kuchepetsa thupi amatha kumwa mankhwala. Kudya pafupipafupi kumatha pafupifupi 2,5-3 kg ndikuchepetsa kuchuluka kwa chakudya chomwe mumadya. Mwa munthu wathanzi, mankhwalawa samachepetsa shuga, kotero angagwiritsidwe ntchito Mlingo woyenera.
Pulogalamu ya Malysheva imati Metformin imathandiza kuchepetsa kunenepa.
Kufunsira kwa ovary ya polycystic
Metformin ndi mankhwala othandizira omwe amagwiritsidwa ntchito pakuchiritsa kovuta kwa kubereka. Akatswiri ena amati kugwiritsa ntchito mankhwalawa kukhala mankhwala oyambira, ena ngati mzere wachiwiri.
Zimathandizira ovulation ndikuthandizira mkazi kutenga pakati. Ndipo monga mukudziwa, ovary ya polycystic ndi endocrinological matenda omwe amatsogolera ku kubereka. Mkaziyo ali ndi insulin kukana.
Chifukwa chake, Metformin ndiyofunikira kwambiri pochiza matenda. Amatchulidwa mu regimen wokhala ndi mahomoni ndi mankhwala ena.
Zotsatira zoyipa
Ndi zabwino zonse za mankhwala, simuyenera kupita kuchipatala. Amatengedwa pazifukwa zachipatala komanso monga adanenera dokotala. Choyamba, ndikofunikira kumvetsetsa kuti Metformin ndi mankhwala. Ndipo mankhwala aliwonse, monga mukudziwa, amayambitsa mavuto.
Zotsatira zoyipa zomwe zimadziwika zimawonetsedwa ndi m'mimba. Nusea iyamba, kulumikizana kwachitsulo kumapezeka mkamwa, tulo tosokosera. Mankhwalawa amatha kusokoneza kuyamwa kwa B12, zomwe zimapangitsa kuti azigwirizana komanso azikumbukira.
Zotsatira zachilendo koma zowopsa za kugwiritsidwa ntchito kosalamulirika kwa Metformin ndi lactic acidosis, vuto limodzi limachitika pa 10,000.
Komabe, kusamala kuyenera kuchitidwa:
- kuloledwa amaloledwa impso wathanzi ndi ntchito yoyenera kusefera;
- osagawiridwa ndi okalamba kwambiri;
- mulingo wa creatinine uzikhala wopyola malire;
- pachipatala chilichonse, kulandila kumayimitsidwa, makamaka ndi maphunziro a x-ray.
Metformin ili ndi zabwino zambiri pakuchiritsa kwake, koma sikuti ndi vuto lenileni. Amatengedwa monga momwe dokotala amafotokozera komanso chifukwa cha zamankhwala. Koma ngati munthu wapezeka ndi matenda a shuga, kumwa mankhwalawa ndikofunikira komanso kothandiza.