Insulin Humulin (Wokhazikika, NPH, M3 ndi M2)

Chimodzi mwa mankhwala abwino kwambiri a anthu odwala matenda ashuga pankhani ya mtengo ndi magwiridwe ake ndi Humulin insulin, yopangidwa ndi kampani yaku America Eli Lily ndi omwe amathandizira nawo m'maiko ena. Mitundu yambiri ya insulini yopangidwa pansi pa dzina ili imaphatikizapo zinthu zingapo. Palinso mahomoni ofupikirako omwe amapangidwira kuti muchepetse shuga mutatha kudya, komanso mankhwala osokoneza bongo apakatikati opangidwa kuti azisinthasintha glycemia.

Palinso zophatikizika zopangidwa mwama insulini awiri oyamba ndikuchita mpaka maola 24. Mitundu yonse ya Humulin yakhala ikugwiritsidwa ntchito pochiza matenda ashuga kwazaka zambiri, ndipo kuweruza ndi ndemanga, apangidwa kwa nthawi yayitali. Mankhwalawa amapereka kwambiri glycemic control, amadziwika ndi kusakhalitsa komanso kudziwikiratu kuchitidwe.

Mitundu ndi mitundu yotulutsidwa kwa Humulin

Insulin Humulin ndi mahomoni omwe amabwerezeranso insulin yopanga thupi la munthu, kapangidwe ka amino acid ndi kulemera kwa maselo. Ndizobwerezanso, kutanthauza kuti, zimapangidwa molingana ndi njira zopangira ma genetic. Mlingo wowerengeka wa mankhwalawa ukhoza kubwezeretsa kagayidwe kazakudya mwa anthu omwe ali ndi matenda ashuga komanso kupewa mavuto.

Matenda a shuga ndi kupsinjika kudzakhala chinthu chakale

• Matenda a shuga -95%
• Kuthetsa kwa mitsempha thrombosis - 70%
• Kuthetsa kwa kugunda kwamtima kwamphamvu -90%
• Kuthana ndi kuthamanga kwa magazi - 92%
• Kuwonjezeka kwa mphamvu masana, kukonza kugona usiku -97%

Mitundu ya Humulin:

1. Humulin Wokhazikika - Ili ndi yankho la insulin yoyera, amatanthauza mankhwala osakhalitsa. Cholinga chake ndikuthandizira shuga kuchokera m'magazi kuti alowe m'maselo, pomwe amagwiritsidwa ntchito ndi thupi mphamvu. Nthawi zambiri imagwiritsidwa ntchito molumikizana ndi insulin yapakatikati kapena yayitali. Itha kuthandizidwa pokhapokha ngati wodwala matenda ashuga ali ndi insulin pump.
2. Humulin NPH - kuyimitsidwa komwe kumapangidwa kuchokera ku insulin yaumunthu ndi protamine sulfate. Chifukwa cha zowonjezera izi, kutsitsa kwa shuga kumayamba pang'onopang'ono kuposa ndi insulin yayifupi, ndipo kumatenga nthawi yayitali. Jakisoni awiri patsiku ndi okwanira kuteteza matenda a glycemia pakati pa chakudya. Nthawi zambiri, Humulin NPH imayikidwa limodzi ndi insulin yocheperako, koma ndi mtundu wa 2 wodwala umatha kugwiritsidwa ntchito pawokha.
3. Humulin M3 - Ichi ndi mankhwala a magawo awiri omwe ali ndi 30% insulin Yokhazikika ndi 70% - NPH. Zomwe zimagwiritsidwa ntchito kwambiri pa Humulin M2, zimakhala ndi 20:80. Chifukwa chakuti gawo la mahomoni limayikidwa ndi wopanga ndipo siliganizira zofuna za wodwala payekha, shuga yamagazi ndi chithandizo chake silingathe kuyendetsedwa bwino ngati mukugwiritsa ntchito insulin yayifupi komanso yapakati. Humulin M3 angagwiritsidwe ntchito ndi odwala matenda ashuga, omwe analimbikitsa chikhalidwe njira ya insulin mankhwala.

Malangizo a nthawi:

Zonse zomwe zimapangidwa ndi Humulin insulin zimakhala ndi U100, motero, ndizoyenera masiku ano a insulin komanso ma syringe.

Kutulutsa Mafomu:

• mabotolo agalasi okhala ndi 10 ml;
• makatoni azitsulo, okhala ndi 3 ml, phukusi la zidutswa 5.

Humulin insulin imayang'aniridwa pang'onopang'ono, mozama - intramuscularly. Kuwongolera kwa intravenous kumaloledwa kokha kwa Humulin Regular, imagwiritsidwa ntchito kuthetsa kwambiri hyperglycemia ndipo iyenera kuchitidwa kokha moyang'aniridwa ndi achipatala.

Zizindikiro ndi contraindication

Malinga ndi malangizo, Humulin ikhoza kuperekedwa kwa odwala onse omwe ali ndi vuto lalikulu la insulin. Nthawi zambiri zimawonedwa mwa anthu omwe ali ndi matenda amtundu wa 1 kapena woposa 2 years. Kuchiza kwa insulin kwakanthawi kochepa kumakhala kotheka ngati muli ndi mwana, chifukwa mankhwala ochepetsa shuga amaletsedwa panthawiyi.

Humulin M3 amangolembera okhawo odwala achikulire, omwe kugwiritsa ntchito njira yolimbikitsira insulin kumakhala kovuta. Chifukwa cha chiwopsezo chowonjezeka cha matenda ashuga mpaka zaka 18, Humulin M3 ali osavomerezeka.

Zotsatira zoyipa:

• Hypoglycemia chifukwa cha mankhwala osokoneza bongo ambiri a insulin, osawerengeka zolimbitsa thupi, kusowa kwa chakudya mu chakudya.
• Zizindikiro za chifuwa, monga zotupa, kutupa, kuyabwa, komanso redness kuzungulira malo a jekeseni. Amatha kuchitika chifukwa cha insulin ya anthu komanso mankhwala othandizira a mankhwalawo. Ngati ziwengo zikupitilira mkati mwa sabata limodzi, Humulin adzasinthidwa ndi insulini ina.
• Kupweteka kapena kupsinjika, palpitations kumatha kuchitika pamene wodwala akusowa kwambiri potaziyamu. Zizindikiro zimatha atachotsa kuchepa kwa macronutrient iyi.
• Sinthani makulidwe amkaka ndi minofu yolowera m'malo opangira jakisoni pafupipafupi.

Odwala ambiri omwe amadziwika ndi Humulin samakumana ndi zovuta zina zina kupatula hypoglycemia.

Humulin - malangizo ogwiritsira ntchito

Kuwerengera Mlingo, kukonzekera jakisoni ndi makonzedwe a Humulin ndi ofanana ndi insulin ina yokonzekera nthawi yofanana. Kusiyanitsa kokha ndi nthawi musanadye. Mu Humulin Nthawi zonse ndi mphindi 30. Ndikofunika kukonzekera kudziwongolera koyamba kwa mahomoni isanakwane, mutawerenga mosamala malangizo ogwiritsa ntchito.

Kukonzekera

Insulin iyenera kuchotsedwa mufiriji pasadakhale kuti kutentha kwa yankho atapeza chipinda. Makatoni kapena botolo la osakanikirana la mahomoni okhala ndi protamine (Humulin NPH, Humulin M3 ndi M2) amayenera kukukhidwira kangapo pakati pa manja anu ndikuwatembenukira kumtunda kuti kuyimitsidwa kumunsi kusungunuke kwathunthu ndipo kuyimitsidwa kumapeza yunifolomu ya milky popanda kulowa. Gwedezani mwamphamvu kuti mupewe kuchuluka kwakanthawi koyimitsidwa ndi mpweya. Humulin Wokhazikika safuna kukonzekera kotero, kumakhala kowonekera.

Kutalika kwa singano kumasankhidwa mwanjira yoti muwonetsetse jakisoni wambiri komanso osalowetsa minofu. Ma cholembera a syringe oyenera insulin Humulin - Humapen, BD-pen ndi fanizo lawo.

Kuyamba

Insulin imalowetsedwa m'malo omwe amakhala ndi minofu yopanga mafuta am'mimba, ntchafu, matako ndi mikono yakumtunda. Kuthiridwa mwachangu komanso kwamayendedwe m'magazi kumayang'aniridwa ndi jakisoni m'mimba, kotero Humulin Regular imakankhidwa pamenepo. Kuti machitidwe a mankhwalawa atsatire malangizo, ndizosatheka kuwonjezera magazi mwanjira ya jakisoni: kupukuta, kukulunga, kuviika m'madzi otentha.

Mukamayambitsa Humulin, ndikofunikira kuti musathamangire: sonkhanitsani khungu lanu mwachangu popanda kumata minofu, pang'onopang'ono mankhwalawa, kenako ndikani singano pakhungu kwa masekondi angapo kuti yankho lisayambike kutayikira. Kuti muchepetse chiopsezo cha lipodystrophy ndi kutupa, masingano amasinthidwa mutatha kugwiritsa ntchito iliyonse.

Machenjezo

Mlingo woyambirira wa Humulin uyenera kusankhidwa molumikizana ndi adokotala. Mankhwala osokoneza bongo amatha kutsitsa shuga komanso kuperewera kwa hypoglycemic. Kuchuluka kwa timadzi tambiri timene timayambitsa matenda a diabetes ketoacidosis, angiopathies osiyanasiyana ndi neuropathy.

Mitundu yosiyanasiyana ya insulin imasiyana mu kuyenera, chifukwa chake muyenera kusintha kuchokera ku Humulin kupita ku mankhwala ena pokhapokha ngati pali zovuta kapena kubwezeredwa kwa shuga. Kusinthaku kumafuna kusintha kwa mlingo komanso kuonjezera, kuwongolera pafupipafupi kwa glycemic.

Kufunika kwa insulin kumatha kuwonjezeka pakusintha kwa mahomoni m'thupi, ndikumamwa mankhwala ena, matenda opatsirana, kupsinjika. Mahomoni ocheperako amafunikira kwa odwala omwe ali ndi hepatic ndipo, makamaka, kulephera kwa aimpso.

Bongo

Ngati insulin yochulukirapo yaikamo kuposa momwe iyenera kuyamwa chakudya chamafuta, wodwala matenda ashuga mosakayikira adzakumana ndi hypoglycemia. Nthawi zambiri zimayendetsedwa ndi kugwedeza, kuzizira, kufooka, ludzu, thukuta, komanso thukuta lotukwana. Mwa odwala matenda ashuga, Zizindikiro zimachotsedwa, kuchepa kwa shuga kotereku ndizowopsa, chifukwa sizingalephereke pakapita nthawi. Pafupipafupi hypoglycemia ndi matenda ashuga neuropathy zimatha kupangitsa kuti azindikire zizindikiro.

Atangochitika za hypoglycemia, imaletseka mosavuta ndi chakudya champhamvu kwambiri - shuga, msuzi wa zipatso, mapiritsi a shuga. Mlingo wamphamvu kwambiri ungayambitse kwambiri hypoglycemia, mpaka kumayambiriro kwa chikomokere. Kunyumba, amatha kutha mwachangu ndi kuyambitsa kwa glucagon, pali zida zapadera zothandizira odwala omwe ali ndi matenda a shuga, mwachitsanzo, GlucaGen HypoKit. Ngati malo ogulitsira a shuga m'chiwindi ndi ochepa, mankhwalawa sangathandize. Njira yokhayo yothandiza pamenepa ndi kupaka shuga mu chipatala. Ndikofunikira kupulumutsa wodwalayo posachedwa, chifukwa chikomacho chimakulirakulira msanga ndipo chimavulaza thupi.

Malamulo osungira a Humulin

Mitundu yonse ya insulini imafunikira malo osungirako apadera. Zomwe zimachitika m'thupi zimasintha kwambiri pakakhala kuzizira, kuwonetsedwa ndi ma radiation ya ultraviolet ndi kutentha pamwamba pa 35 ° C. Soko imasungidwa mufiriji, pakhomo kapena pashelufu kutali ndi khoma lakumbuyo. Moyo wa alumali molingana ndi malangizo ogwiritsira ntchito: zaka zitatu za Humulin NPH ndi M3, zaka 2 kwa Wokhazikika. Botolo lotseguka limatha kutentha kutentha kwa 15-25 ° C kwa masiku 28.

Zotsatira za mankhwala a humulin

Mankhwala amatha kusintha zotsatira za insulin ndikukulitsa chiopsezo cha mavuto. Chifukwa chake, popereka mahomoni, dokotala amayenera kupereka mndandanda wathunthu wa mankhwala omwe atengedwa, kuphatikizapo zitsamba, mavitamini, zowonjezera pazakudya, zowonjezera zamasewera ndi njira zakulera.

Zotsatira zake:

Zomwe zimagwiritsidwa ntchito pa nthawi yapakati

Pofuna kupewa kutaya mtima kwa mwana wosabadwayo panthawi yomwe ali ndi pakati, ndikofunikira kuti azikhala ndi glycemia wanthawi zonse. Mankhwala a Hypoglycemic ndi oletsedwa panthawiyi, chifukwa amasokoneza kaperekedwe ka chakudya kwa mwana. Njira yokhayo yovomerezeka pakadali pano ndi ya insulin yayitali komanso yochepa, kuphatikiza Humulin NPH ndi Wokhazikika. Kukhazikitsidwa kwa Humulin M3 sikofunikira, chifukwa sikutha kulipirira bwino shuga.

Pa nthawi yobereka, kufunika kwa mahomoni kumasintha kangapo: kumachepa mu trimester yoyamba, kumawonjezeka kwambiri mu 2 ndi 3, ndipo kumatsika kwambiri pambuyo pobadwa mwana. Chifukwa chake, madokotala onse omwe amayendetsa pakati ndi kubereka ana ayenera kudziwitsidwa za kupezeka kwa matenda ashuga mwa akazi.

Analogi

Chingalowe m'malo mwa Humulin insulin ngati zotsatira zoyipa:

Tebulo ili limangofanizira mndandanda wathunthu - mwanjira ya anthu opanga majini okhala ndi nthawi yayitali.