Ultrashort insulin pakuwoneka ndi zinthu zowoneka bwino zamadzimadzi ndipo imachitika mwachangu. Nthawi zambiri, insulin yocheperako pang'ono imayamba kugwira ntchito mthupi la munthu yemwe akudwala matenda a shuga 1-20 mphindi pambuyo pobayidwa.
Kuchuluka kwa machitidwe a mankhwala kumachitika ola limodzi pambuyo pakukonzekera, ndipo zotsatira za mankhwalawa zimatha kwa maola atatu mpaka asanu. Ma insulin osakhalitsa pakanthawi kochepa amagwiritsidwa ntchito atangodya ndipo amapangidwira kuthana ndi hyperglycemia yomwe mosalephera imapezeka m'thupi la wodwala yemwe ali ndi matenda ashuga atatha kudya.
Ma insulin otsatirawa akupezeka pakadali pano kwa odwala:
- Apidra (insulin glulisin);
- NovoRapid (insulin aspart);
- Humalog (insulin lyspro).
Mitundu yonse ya insulini yomwe imagwira mwachangu imapangidwa kuti ikwaniritse maulamuliro a subcutaneous, kupatulapo aspart ndi lispro, omwe ali ndi mwayi wowonjezereka wobweretsedwa ndi jekeseni wa intravenous.
Insulin yothamanga kwambiri ndi imodzi mwazinthu zaposachedwa kwambiri pantchito zamankhwala. Kutalika kwake ndi kochepa kwambiri. Insulin yachilengedwe yopangidwa ndi anthu imapangidwa ngati analogue ya ultrashort insulin. Mankhwalawa adagwiritsidwa ntchito poyambirira pomwe kupumula kungayembekezere odwala.
Mankhwala osokoneza bongo amtunduwu amatha kugwiritsidwa ntchito pochiza matenda onse a shuga. M'kati mwa ntchito yake, insulini yolimbitsa thupi imatsitsa shuga m'magazi am'magazi kupita ku zikhalidwe zathupi.
Ultrafast kanthu insulin mawonekedwe
Insulin ya Ultrafast imatha kudziwika ndi zizindikiro zotsatirazi. Kukhazikitsidwa kwa mankhwalawa m'thupi la wodwalayo kumachitika m'njira ya jekeseni wamkati pamimba. Njirayi ndi yochepetsetsa kwambiri yopereka mankhwala kwa wodwala.
Insulin yothamanga kwambiri iyenera kulowetsedwa m'thupi nthawi yomweyo musanadye. Nthawi yayitali kwambiri pakati pa jakisoni ndi chakudya sayenera kupitirira mphindi 30.
Ultrashort insulin imayendetsedwa kokha malinga ndi chakudya. Pambuyo poyambitsa, chakudya chimafunika. Pakadutsa zakudya zomwe zimayambitsidwa ndi wodwalayo m'thupi la wodwala, hypoglycemia imatha kukhazikika, komwe kumachepa kwambiri kuchuluka kwa shuga m'madzi a m'magazi.
Kuphatikizika koyamba kwa insulini mwa njira zochita kupanga kunachitika mu 1921. Ndi chitukuko chowonjezereka cha makampani opanga mankhwala, mitundu ingapo ya mankhwala yatengedwa, maziko ake ndi insulin.
Insulin ya Ultrafast imagwiritsidwa ntchito kuthana ndi kusinthasintha kwa nsonga ya plasma glucose pambuyo podya.
Kuwerengera kuchuluka kwa insulini yomwe imagwiritsidwa ntchito kumachitika kokha ndi endocrinologist. Malinga ndi mawonekedwe a thupi la wodwalayo. Kodi chifukwa chiyani kugwiritsa ntchito mankhwala osokoneza bongo kuli koyenera?
Mtundu wa insulin womwe umagwira mwachangu m'thupi la munthu umapangidwa kuti ukhale wofanana ndi insulin yake pachakudya chamafuta ambiri othamanga.
Pazomwe tikuwerenga mungathe kuwerenga zambiri zokhudzana ndi insulin yofunika m'thupi.
Kugwiritsa ntchito mankhwala a insulin omwe ali ndi vuto la ultrashort
Malangizo apadera ogwiritsira ntchito kukonzekera kwa insulin mwachangu kumakhudzanso kuyambitsa kwa mankhwala panthawi inayake musanayambe kudya. Malinga ndi malangizo ogwiritsira ntchito, nthawi yomwe pakati pakubaya ndi kugwiritsa ntchito chakudya iyenera kukhala yaying'ono.
Kutalika kwa nthawi pakati pa jakisoni ndi chakudya zimadalira kwambiri pamunthu payekha. Nthawi yogwiritsira ntchito mankhwala omwe ali ndi insulin musanadye imachitika ndi endocrinologist.
Mukamawerengera dongosolo la mankhwala, mawonekedwe onse a munthu omwe ali ndi matenda a shuga 1 ayenera kuganiziridwanso.
Mukamagwiritsa ntchito kukonzekera kwa ultrashort, malangizo ogwiritsira ntchito ndi malingaliro omwe adalandira kuchokera kwa endocrinologist ayenera kuonedwa bwino. Chofunikira kwambiri ndikudziwikirana kwa nsonga za mankhwala omwe amagwiritsidwa ntchito jekeseni ndi zakudya.
Kuphatikizika kwa nsonga zakuchita kwa mankhwala mthupi ndi kuchuluka kwa kulowa kwa glucose m'madzi amwazi kumapewetsa thupi, lomwe lili pafupi ndi hyperglycemia. Kulephera kutsatira malingaliro mukamamwa mankhwala a ultrashort kungayambitse kukula kwa hypoglycemia m'thupi. Izi zimachitika pambuyo pobweretsa mankhwala osadya chakudya. Mlingo wa mankhwalawa amawerengedwa m'njira yoti glucose yemwe amalowa mthupi azitha kugwiritsidwa ntchito nthawi yomweyo.
Mukamagwiritsa ntchito insulin ya ultrafast, ndikofunikira kutsatira lamuloli - zakudya ziyenera kumwedwa pamlingo womwe mankhwala amapangidwira.
Ngati chakudya chikhala chosakwanira m'thupi la wodwalayo, vuto la hypoglycemia limayamba, ndipo pena paliponse, mkhalidwe wa hyperglycemia umayamba. Zosankha zoterezi pakukula kwa matendawa zimakhala ndi zowopsa pamthupi la wodwalayo.
Kugwiritsira ntchito insulin ya ultrafast kumangolembedwa pokhapokha ngati kukula kwa glucose m'thupi kumawonedwa pokhapokha pakudya.
Munthawi imeneyi, kumwa mankhwala amtunduwu kumakupatsani mwayi wowonjezera shuga m'thupi.
Ultrafast insulin regimen
Pogwiritsa ntchito chipangizo chamtunduwu mankhwala, zofunika zina ndi malangizo ziyenera kutsatiridwa, zomwe ndi izi:
- Jakisoni wa mankhwalawa amayenera kuchitika pokhapokha chakudya chofunikira, mosasamala mtundu wa insulin yomwe imagwiritsidwa ntchito mwachangu.
- Pobayira, gwiritsani ntchito syringe yapadera ya insulin.
- Dera lomwe mumakonda ndi jakisoni.
- Jekeseni asanafike, jakisoniyo sayenera kutenthedwa, izi zimathandizira kuti magazi ayambe kuyenda bwino m'magazi.
- Kuwerengera kwa mankhwalawa omwe agwiritsidwa ntchito pochiza mankhwalawa kuyenera kuchitika payekhapayekha. Dokotala ayenera kuphunzitsa wodwala za kuchuluka kwa mankhwalawa ofunikira jakisoni.
Mukamagwiritsa ntchito mankhwalawa, munthu ayenera kukumbukira kuti kuchuluka kwa mankhwalawo komanso nthawi yomwe insulin ingalowe mthupi, ndalamazo ziyenera kukhala zokhazikika, ndipo malo oyendetsera mankhwala ayenera kusintha.
Mukamagwiritsa ntchito mankhwala, malamulo oyang'anira mankhwalawa amayenera kusamalidwa bwino. Izi zimafunikira kuti mankhwala omwe ali ndi insulini asasinthe katundu wake ndipo mlingo wowongolera thupi umawerengeredwa molondola.
Kuchita kwa insulini wa ultrafast kumayamba kale kuposa momwe thupi limakhalira ndi nthawi yonyamula chakudya chama protein ndi kuchiyika mu glucose. Ndi zakudya zoyenera, kugwiritsa ntchito insulin yochepa kwambiri sikufunika. Mankhwalawa amayenera kumwedwa pokhapokha ngati pakufunika kusintha mwachangu kuchuluka kwa shuga m'magazi a munthu wodwala matenda a shuga.
Kuchuluka kwa glucose wa nthawi yayitali kumabweretsa zotsatirapo zoyipa, kuwonjezeka kwa shuga m'magazi kumakhala ndi zotsatira zoyipa thupi, pofuna kupewa zochitika ngati izi, mankhwala omwe ali ndi insulin ya ultrafast amagwiritsidwa ntchito.
Chifukwa chakufupika kwakanthawi, mankhwalawa amasintha msanga mthupi mwambiri, ndikuwabweretsa pafupi ndi nthawi yachilengedwe.
Ngati munthu wodwala matenda ashuga azitsata zonse zofunikira pakudya m'thupi, ndiye kuti insulini yotsiriza siyofunikira kwa iye, imagwiritsidwa ntchito pokhapokha pakuwonjezeka kwadzidzidzi mu shuga kuti mubwezeretse.
Zoyipa zamagetsi pogwiritsa ntchito ultrafast insulin
Insulin yokhala ndi ultrafast action imakhala ndi nthawi yochepa kwambiri yogwirira ntchito ndipo mulingo wake m'magazi a wodwalayo umachepa mwachangu kwambiri. Popeza chiwopsezo chochita mankhwalawa ndi chakuthwa kwambiri, kuwerengetsa kwa muyezo wa mankhwalawa kuti mugwiritse ntchito kumakhala ndi zovuta zake. Zonse zomwe zimagwiritsidwa ntchito pakugwiritsa ntchito insulin yotereyi zikuwonetsedwa mu malangizo omwe mungagwiritse ntchito.
Mchitidwe wogwiritsa ntchito mankhwala amtunduwu akuwonetsa kuti zotsatira za insulin pamthupi la wodwala yemwe ali ndi matenda osokoneza bongo a mellitus ndizosakhazikika komanso zamphamvu kwambiri poyerekeza ndi mitundu ina ya mankhwala okhala ndi insulin omwe amagwiritsidwa ntchito pochiza matenda ashuga.
Kugwiritsa ntchito mankhwalawa kumangofunikira pokhapokha. Chitsanzo cha zoterezi zitha kukhala ulendo wopita kumalo odyera kapena kuyenda pandege.
Mukamawerengera kuchuluka kwa insulin ya ultrafast, odwala ambiri amasintha kwa dokotala. Koma kuti moyo ubwerere mwakale, zimafunikanso kuti wodwala azikhala ndi vuto loti azikwaniritsa.
Sikovuta kuwerengera kuchuluka kwa insulini yothamanga kwambiri. Pachifukwa ichi, kuyang'anira shuga nthawi zonse m'madzi a m'magazi kumafunika. M'pofunika kudziwa nthawi yakumayambiriro kwa kudumpha m'magazi a glucose - mphindi iyi ndiyo nthawi yoyambitsa mankhwala a ultrafast.
Kuwerengera moyenera kuchuluka kwa mankhwala omwe amagwiritsidwa ntchito kumafuna chisamaliro chapadera. Kuwerengera koyenera, mankhwalawa amathandizira odwala matenda ashuga ndipo samapereka zovuta. Kanemayo munkhaniyi pamayimbidwe omwe mafuko amalankhula za ultrashort insulin.
