Glipizide ndi mankhwala omwe ali m'gulu la mankhwala ambiri a hypoglycemic kuti azitha kuyendetsa shuga m'magulu 2 a shuga.
Kugwiritsa ntchito kake kumakhala koyenera ngati chakudya ndi masewera olimbitsa thupi sangapereke kuchepa kwa kuchuluka kwa shuga, komanso zovuta za microangiopathy, ndiye kuti, kuwonongeka kwa mitsempha yaying'ono ya magazi.
Asanayambe kumwa mankhwalawa, wodwalayo ayenera kudziwa momwe angagwiritsidwire ntchito mankhwalawo ndipo muzochitika ziti zomwe zimatsutsana? Kuphatikiza apo, ndikofunikira kuti muphunzire ndemanga zamankhwala a odwala ndi madokotala, ndipo ngati ndi kotheka, ndikuphunziranso zomwe zikufanana ndi Glipizide.
Zambiri pazambiri
Ichi ndi chipangizo chopangira hypoglycemic.
Glipizide sangathe kusungunuka m'madzi kapena mowa, komabe, yankho la NaOH (0,1 mol / L) ndi dimethylformamide sungunulani gawo ili bwino. Izi zimapangidwa m'mapiritsi wamba ndi mapiritsi othandizira osintha.
Zinthu zikalowa m'thupi la munthu wodwala matenda ashuga, zimalimbikitsa kutulutsa insulini kuti isagwire ntchito ya beta.
Glipizide amachita motere:
- Amachepetsa shuga ndi glycosylated hemoglobin pamimba yopanda kanthu.
- Kuchuluka kwa kulolera kwa glucose, komanso pang'ono - kutulutsa kwamadzi free.
- Amachepetsa mwayi wa hyperglycemia mukatha kudya.
Gawo lochita silikukhudza kagayidwe ka lipid. Kutsegulira kwake kumayamba pambuyo pa mphindi 30 kuvomerezedwa ndikupitilira tsiku lonse. Kuzindikira kwakukulu kwa chinthu kumawonedwa pambuyo pa maola atatu ndi atatu pakumwa.
Tiyenera kudziwa kuti Glipizide ndibwino kuti musagwiritse ntchito mukamadya, popeza mayamwidwe ake onse amayamba kuchepa. Kuphatikizika kwa zinthu kumachitika m'chiwindi.
Gawolo limapukusidwa monga metabolite limodzi ndi ndowe ndi mkodzo, kuphatikizapo osasinthika - pafupifupi 10%.
Malangizo ogwiritsira ntchito
Musanagwiritse ntchito zokonzekera zomwe muli ndi glipizide, muyenera kufunsa dokotala kapena endocrinologist. Ndi dokotala yekha yemwe angawunikenso moyenera kugwiritsa ntchito njira imodzi kapena ina.
Mukamagula mankhwalawo, muyenera kuwerenga kabuku kosamalitsa mosamala. Mlingo woyambirira ndi 5 mg, womwe umaperekedwa kamodzi patsiku asanadye kapena pambuyo chakudya. Popita nthawi, mukakhala ndi thanzi labwinobwino la shuga, mulingo ungathe kuchepetsedwa mpaka 15 mg, ndikugawa makonzedwe a mankhwalawa kangapo.
Malangizowo akunena kuti ngati mankhwalawo adaphonya, koma maola ochepa adapita kuchokera pamene mulingo wofunikira, mankhwalawa amayenera kuperekedwa mwachangu. Koma ngati pafupifupi tsiku latha, njira zochiritsira zamasiku onse ziyenera kutsatiridwa.
Odwala okalamba komanso odwala matenda a chiwindi ayenera kugwiritsa ntchito mankhwalawa osachepera - 2,5 mg patsiku, ndi mapiritsi a nthawi yayitali - kuyambira 5 mpaka 10 mg kamodzi, makamaka m'mawa.
Monga mankhwala ena onse, Glipizide iyenera kusungidwa kutali ndi ana m'malo otetezedwa ndi chinyezi kutentha kwa chipinda.
Contraindication ndi zomwe zingavulaze
Mitundu ina ya odwala matenda ashuga sangathe kulandira mankhwalawa.
Malangizo omwe aphatikizidwa ali ndi contraindication okhudzana ndi kukhudzidwa ndi vuto la munthu, matenda ashuga, mtundu wodwala wa insulin, ketoacidosis, malungo, opaleshoni yaposachedwa, pakati komanso nthawi yoyamwitsa.
Muzovuta kwambiri, kugwiritsa ntchito Glipizide ndikotheka pakubala kwa mwana. Koma kugwiritsa ntchito kwake kuyenera kuti kuthetsedwe mwezi umodzi tsiku lobadwa lisanachitike.
Pa yoyamwitsa, kumwa mankhwalawa ndizoletsedwa.
Kufunsira kwa dokotala musanagwiritse ntchito Glipizide ndikofunikira, chifukwa kuperewera molakwika kwa mankhwalawa kumatha kubweretsa zotsatirapo zambiri zosavomerezeka:
- mutu, kusokonezeka kwa chikumbumtima, kutopa, kutaya mtima, chizungulire, kupsinjika, paresthesia, nkhawa, kupweteka kwa m'maso ndi conjunctivitis;
- flatulence, nseru, kusanza, zosayenera zamwazi mu ndowe, kudzimbidwa, dyspepsia ndi anorexia;
- kuyabwa, zotupa, ndi ming'oma;
- pharyngitis, rhinitis ndi dyspnea;
- mogwirizana ndi mtima dongosolo ndi magazi mapangidwe: arrhythmia, syncope, kumverera kwa kutentha kwamphamvu ndi matenda oopsa;
- komanso glycemia wa mtundu 2 wa shuga wambiri mpaka kukomoka kwa glycemic.
- zokhudzana ndi genitourinary system: utachepa chilakolako chogonana komanso dysuria.
Kuphatikiza apo, zovuta zina zingapo zimatha - kupweteka, ludzu losatha, myalgia, arthralgia, thukuta, kupweteka kwa thupi.
Mtengo, ndemanga ndi fanizo
Popeza glipizide ndi gawo logwira ntchito, mankhwala ambiri okhala ndi zoterezi amatha kupezeka pamsika wa Russia. Mwachitsanzo, Glucotrol CL ndi Glibenez Retard. Kutengera mtundu wa kumasulidwa, mtengo wa mankhwalawa Glucotrol HL umachokera ku rubles 280 mpaka 360, ndi Glibenez Retard - kuchokera ku ruble 80 mpaka 300.
Ndemanga za anthu ambiri odwala matenda ashuga omwe adamwa mankhwalawa ndiwokhutiritsa. Komabe, ambiri adazindikira kuti achire zotsatira za glipizide zimatsika pakapita nthawi, chifukwa chake nthawi zambiri zimagwiritsidwa ntchito limodzi ndi mankhwala ena a matenda ashuga. Mwa zabwino za mankhwalawa zimadziwika kuti ndizovuta kugwiritsa ntchito komanso mitengo yokhulupirika ya mankhwala omwe ali ndi glipizide.
Mu milandu ngati mankhwala amodzi sayenera chifukwa chobwerekera kapena chifukwa chosagwirizana, dokotala amalembera analogue. Mankhwalawa akuphatikizapo:
- Movoglek.
- Antidiab.
- Glibenesis.
- Minidiab.
Popanda kuvomerezedwa ndi dokotala, kudzipereka nokha sikofunika. Kukonzekera komwe kumakhala ndi glipizide kumatha kukhala osokoneza thupi. Mukamagwiritsa ntchito moyenera mankhwalawa, mutha kusintha kuchuluka kwa shuga ndikuchotsa zizindikiro za matenda ashuga. Komanso sitiyenera kuyiwala zamankhwala olimbitsa thupi a shuga ndi zakudya zoyenera.
Mu kanema munkhaniyi, adokotala azikambirana za mankhwala osokoneza bongo.
