Diabeteson MV 60 mg: malangizo ndi kuwunika, zikuonetsa, mtengo

Diabeteson MV 60 mg; malangizo ogwiritsidwira ntchito akuwonetsa kuti mankhwalawa amaphatikizidwa pagulu lachiwiri la sulfonylurea.

Chidachi chimagwiritsidwa ntchito moyenera pothandizira matenda a shuga, ndikupanga mawonekedwe a insulin popanda kudziimira.

Zovuta za gulu ili la mankhwala mthupi la munthu zimagwirizanitsidwa ndi kayendedwe ka ma cell a pancreatic beta, omwe amasinthidwa ndikuwonetsa kwambiri insulin.

Kugwiritsa ntchito mankhwala a sulfonylurea kumachitika pamaso pa maselo a beta ogwira ntchito mokwanira m'thupi.

Amayendedwe a gulu la mankhwala awa akuwonetsa zotsatirazi:

• kukondoweza kwa maselo a pancreatic beta ndikuwonjezera kwawo kumverera kwa ma cell;
• kuchuluka kwa insulin ndi kuponderezana kwa mahomoni omwe amawononga (insulinase);
• kufooketsa ubale wa insulin ndi mapuloteni, kuchepetsa kuchuluka kwa insulin kwa ma antibodies;
• amathandizira kukulitsa chidwi cha minofu ndi lipid minofu zolandirira insulin;
• onjezerani kuchuluka kwa zolandilira m'matumbo;
• amathandizira kukonza magwiritsidwe a shuga mu chiwindi ndi minofu;
• sokoneza njira ya gluconeogeneis mu chiwindi;
• mu lipid zimakhala zimachepetsa lipolysis komanso zimachulukitsa mayamwidwe ndi oxidation wa glucose.

Mpaka pano, pali mitundu ingapo ya mankhwala ochokera ku sulfonylureas:

1. Mankhwala a m'badwo woyamba omwe sagwiritsidwa ntchito ngati mankhwala amakono - Tolazamide, Carbutamide.
2. Mbadwo wachiwiri, womwe Glibenclamide, Gliclazide ndi Glipizide ndiwo oimira.
3. M'badwo wachitatu ndi glimepiride.

Kusankha kwa mankhwala omwe agwiritsidwa ntchito kuyenera kuchitika ndi adokotala.

Kodi wothandizira hypoglycemic ndi chiyani?

Mankhwala a shuga a shuga ndi othandizira odwala matenda a shuga.

Mankhwalawa amatha kupangidwa mosiyanasiyana, kutengera kuchuluka kwa zinthu zomwe zikuchitika - 60 ndi 80 milligrams.

Chofunikira chachikulu ndi gliclazide - m'modzi mwa oyimira m'badwo wachiwiri wa sulfonylurea. Mtundu womasulidwa wa mankhwalawo ndi mapiritsi okhala ndi tulo.

Tiyenera kudziwa kuti Diabeteson MV wokhala ndi mulingo wa 60 mg amaperekedwa mwa mawonekedwe a mankhwala omwe amasulidwa.

Mapiritsi a matenda ashuga amagwiritsidwa ntchito motere:

• mu mankhwalawa achire odwala omwe amapezeka ndi shuga;
• kuteteza chitukuko cha mavuto a matenda, kuphatikizapo kuchepetsa chiopsezo cha nephropathy ndi retinopathy, stroke ndi myocardial infarction.

Gawo lomwe limagwira ndi gawo limodzi la mankhwalawa limathandizira kuchepetsa kuphatikiza ndi kuphatikizika kwa mapulosi, limalepheretsa chitukuko cha parietal thrombus ndipo limakhala ndi phindu lonjezerani ntchito ya mtima.

Kuphatikiza apo, pa mankhwala, matenda a mtima amadziwikanso.

Ubwino wa Diabeteson MV 60 mulinso:

1. Ili ndi machitidwe a antiatherogenic, omwe amadziwonetsera okha mu mawonekedwe a cholesterol komanso kuchepa kwa chiwombolo chaulere.
2. Zimalepheretsa kuwoneka ndi kukula kwa microthrombosis ndi atherosulinosis.
3. Imachepetsa mphamvu ya mtima ku adrenaline.

Pambuyo pakugwiritsira ntchito mankhwalawa, kuchuluka kwake m'madzi am'magazi kumawonjezeka kuposa maola asanu ndi limodzi, pambuyo pake kumakhalabe kwa nthawi ina kuchokera maola 6 mpaka 12.

Malangizo ogwiritsira ntchito mankhwalawa

Mankhwala a Diabeteson mr 60 amagwiritsidwa ntchito pochiza matenda a matenda okha a akulu okha.

Kwa wodwala aliyense, dokotala yemwe amapita amakhala ndi ndandanda ya kumwa mankhwalawo pakumwa.

Zofunikira za kugwiritsa ntchito mankhwalawa zimafotokozedwa mwatsatanetsatane momwe angagwiritsidwire ntchito mankhwalawa.

Malinga ndi malangizo ogwiritsira ntchito mankhwalawa, mankhwalawa amayenera kumwa potsatira dongosolo lotsatira:

1. Kamodzi patsiku, ngakhale kudya kudya. Poterepa, tikulimbikitsidwa kugwiritsa ntchito piritsi m'mawa, nthawi yam'mawa.
2. Tengani mapiritsiwo pakamwa ndi madzi okwanira.
3. Mlingo watsiku ndi tsiku umatha kukhala 30 mpaka 120 mg wa mankhwala othandizira, omwe mapiritsi a 0.5-2 panthawi imodzi.
4. Mlingo wofunikira wa mankhwalawa umayikidwa ndi dokotala aliyense payekha kwa wodwala aliyense, poganizira mawonekedwe a matendawa.
5. Ngati mwanjira iliyonse chithandizo chotsatira chanasemphana, palibe chifukwa chowonjezera mlingo wotsatira
6. Kuyamba kwa chithandizo chamankhwala ndibwino kuti muyambe ndi mlingo wotsika kwambiri, womwe ndi theka la piritsi la Diabeteson MV 60 mg. Kuphatikiza apo, mulingo womwewo ungagwiritsidwe ntchito kusunga kufunika monga chithandizo chothandizira.
7. Kuwonjezeka kwa Mlingo kuyenera kuchitika pang'onopang'ono kuchokera ku mamiligalamu makumi atatu a mankhwala othandizira. Pakapita kanthawi, katswiri wa zamankhwala asankha kuiwonjezera koyamba mpaka 60 mg, kenako mpaka 90 ndi 120 mg ya chinthu chomwe chikugwira ntchito. Dziwani kuti mutayamba kugwiritsa ntchito mankhwalawa, kuchuluka koyamba kwa mankhwalawa sikungatheke kuposa mwezi umodzi.
8. Mlingo woyenera wa mankhwala patsiku uyenera kukhala 120 mg.

Nthawi zina, kuphatikiza mankhwala kumachitika. Piritsi la diabeteson MV 60 lingagwiritsidwe ntchito molumikizana ndi mankhwala ochokera m'magulu a Biguanide, alpha glucosidase inhibitors, kapena insulin.

Kwa magulu ena a odwala, kusintha masinthidwe ofotokozedwawo kungakhale kofunikira. Izi zikuphatikiza:

• anthu omwe ali ndi vuto lalikulu la impso;
• omwe ali pachiwopsezo cha kukhala ndi hypoglycemia.

Gulu la anthu omwe ali pachiwopsezo cha kukhala ndi hypoglycemia limaphatikizapo odwala omwe alibe chakudya chokwanira, kutsatira zakudya okhwima kapena kusala, matenda a endocrine, carotid arteriosranceosis.

Piritsi imatha kugwiritsidwa ntchito ngati njira yovuta kuti ikwaniritse kukhazikika kwa hypoglycemic kapena ngati njira yodzitetezera motsutsana ndi zovuta zamatenda a matenda. Katswiri wa zaumoyo atha kukupatsirani mankhwala othandizira pogwiritsa ntchito metformin hydrochloride, alpha-glucisidase inhibitors, kapena thiazolinedione.

Kugwiritsa ntchito mankhwala, ndikofunikira kuyang'anira kuchuluka kwa shuga m'magazi kuti mupewe kukula kwa hypoglycemia.

Ndi nthawi ziti pamene ndizoletsedwa kugwiritsa ntchito hypoglycemic wothandizira?

Monga mankhwala aliwonse, a Diabeteson MV 60 ali ndi mndandanda wina wa contraindication kuti mugwiritse ntchito.

Ngakhale pali mndandanda wazakudya zabwino za mankhwalawo, ndikofunikira kuganizira mitundu yonse ya zinthu zoyipa zomwe zingachitike mutagwiritsidwa ntchito.

Choyamba, ndikofunikira kulabadira mndandanda wa zoletsa zomwe chithandizo chachipatala sichingachitike.

Zina mwazinthu zazikuluzikulu zomwe zikuphatikizidwa ndi izi:

• mankhwalawa 1 matenda a shuga;
• ngati kuwunika kwa matenda ashuga ketoocytosis kapena mkhalidwe wa kholo la odwala matenda ashuga wodwala;
• mawonetseredwe a hypoglycemia wodwala;
• pamaso pa pathologies a matenda;
• chiwindi chachikulu kapena matenda a impso amayamba;
• tsankho kapena hypersensitivity ku chimodzi kapena zingapo za mankhwala;
• leukopenia;
• boma pambuyo pancreatic resection;
• mukumwa miconazole;
• pamaso pa lactose tsankho kapena lactase akusowa.

Mpaka pano, palibe chidziwitso chokwanira chokhudza momwe mankhwalawa amagwirira ntchito pochiza matenda a shuga kwa ana. Ichi ndichifukwa chake mankhwalawa sanalembedwe kwa odwala otere (mpaka zaka khumi ndi zisanu ndi zitatu). Kuphatikiza apo, contraindication imaphatikizanso kumwa mankhwalawa kwa atsikana ndi amayi oyembekezera panthawi yoyamwitsa.

Komanso, mosamala kwambiri, mankhwalawa amalembedwera milandu motere:

1. Ngati pali chiopsezo chowonjezeka cha hypoglycemia.
2. Ngati pali zinthu zina zomwe zimafunika kuti wodwala azilowetsa jakisoni wa insulin.
3. Pambuyo pochita opaleshoni.

Kuphatikiza apo, mosamala kwambiri, mankhwalawa ayenera kugwiritsidwa ntchito ngati wodwala ali ndi matenda am'mimba.

Zotheka kukhala ndi mavuto

Ndemanga za odwala omwe amagwiritsa ntchito mankhwalawa nthawi zambiri zimakhala zabwino.

Kuunikiridwa kwa madotolo kukuwonetsa kuti kuyendetsa molakwika chipangizo chachipatala kumatha kuyambitsa zovuta zingapo, zomwe zimakhala zovuta.

Kusokonezeka pamagulu abwinobwino ka ziwalo ndi machitidwe osiyanasiyana kumatha kuchitika mosiyanasiyana komanso kuzungulira kosiyanasiyana.

Zoyipa zazikulu ndizoti:

• kuphwanya kwam'mimba kumawonekera mwa mawonekedwe amtundu wam'mimba, kupweteka pamimba, kutsekemera kwazitsulo pamkamwa, pakamwa, nseru, kusanza kapena kutsekula m'mimba;
• chitetezo cha mthupi chimatha kugwiranso ntchito poyambira njira zochizira matenda a phenura, kuyabwa kwa khungu kapena urticaria, kuchuluka kwa photosensitivity, erythema, edema ya Quincke;
• zovuta zoyipa yozungulira yozungulira imakhala ndi zizindikiro zotsatirazi - thrombocytopenia, hemolytic anemia mu shuga mellitus, leukopenia, erythropenia;
• mavuto ndi yachibadwa ntchito kwa chiwindi zitha kuwoneka ndi matenda monga chiwindi kapena cholestatic jaundice;
• kupezeka kwa kanthawi kovuta kwamankhwala owoneka;
• Kusankhidwa bwino kwa Mlingo wa mankhwalawa kumabweretsa kukula kwa hypoglycemia, zizindikiro zake zazikulu ndikuwoneka kwa kutentha, kutopa, manja akunjenjemera, kumverera kofala kwa kutopa ndi kuchuluka kwa kugona;
• kuchuluka kwambiri kwa thupi.

Mankhwala osokoneza bongo omwe amapezeka palimodzi ndi zotsatirazi:

1. Kuchulukitsa thukuta.
2. Kumva njala mosalekeza.
3. Kuyankhula molakwika komanso kuzindikira.
4. Maonekedwe a mavuto ndi tulo.

Ndi bongo wambiri, mawonekedwe ndi kupititsa patsogolo kwa zizindikiro za hypoglycemia ndizothekanso.

Ndi mankhwala ati omwe angalowe m'malo mwa mankhwala a hypoglycemic?

Mtengo wa mankhwalawa Diabeteson MV ukhoza kusiyana ndi ma ruble 280 m'masitolo osiyanasiyana amzindawu.

Wopanga wamkulu wa mankhwalawo ndi mankhwala ochepetsa shuga ndi France.

Chifukwa cha momwe mankhwalawo amachokera kunja, odwala nthawi zambiri amakhala ndi chidwi chofuna kudziwa ngati pali mankhwala okhala ndi analogue ndipo mtengo wake ndi chiyani?

M'malo mwake mankhwalawa ndi mapiritsi otsatirawa:

• Diabefarm MV;
• Glidiab ndi mawonekedwe osinthika a Glidiab MV;
• Gliclazide-acos MV;
• Glucostabil.

Mu iliyonse yamankhwala omwe ali pamwambawa, pali gawo lina la Gliclazide.

Kuyika (mapiritsi 60) Glidiab yokhala ndi Mlingo wa 80 mg umawononga pafupifupi ma ruble 120. Wopanga mankhwalawa ndi Russian Federation. Ndi chithunzi chonse cha mankhwala a shuga a 80.

Kukonzekera piritsi Gliclazide MV ndi njira yosinthira yotulutsidwa ya hypoglycemic. Mankhwalawa amakapangidwa pamaziko a gliclazide ndipo amatha kukhala ndi mitundu yosiyanasiyana ya yogwira (30 kapena 60 mg). Ntchito yake yayikulu ndikusintha magazi m'magazi chifukwa chakuchepa kwa chakudya komanso zolimbitsa thupi. Mtengo wa mankhwala ndi wotsika mtengo kuposa mtengo wa Diabeteson MV ndipo umachokera ku ma ruble 128.

Analog ya ku Russia ya Diabefarm MV ingagulidwe kuzipatala zamzindawo pafupifupi ruble 130 (mapiritsi 60). Piritsi lodziwikiratu siligwirizana pakapangidwe kenakake kamomwe kamagwira, koma kusiyana kwa ofunikira, zikuonetsa, zotsutsana ndi kuthekera kwa mavuto kuchokera ku mankhwala a Diabeteson MV.

Nthawi zina, dokotala yemwe amapezekapo akhoza kumwa mapiritsi a Diabeteson MV ndi mankhwala ena:

1. Kuchokera pagulu la sulfonylurea, koma ndi chinthu china chophatikizika компон
2. Mankhwala ochokera pagulu lina, koma ofanana ndi mankhwala (glinides) ꓼ

Komanso, kugwiritsidwa ntchito kwa Diabeteson MV kungathe kulowa m'malo mwa mankhwala omwe ali ndi mfundo yofananira (DPP-4 inhibitors).

Momwe mankhwala ochepetsera shuga amagwirira ntchito Diabeteson MV adzafotokozedwa ndi katswiri mu kanema munkhaniyi.