Diabeteson MV ndimachiritso a matenda ashuga amtundu wa 2. Zomwe zimagwira ndi gliclazide. Zimapangitsa maselo a kancreatic pancreatic beta kuti apange insulin yambiri, yomwe imatsitsa shuga. Zimatanthauzira zochokera ku sulfonylurea. MB ndi mapiritsi otulutsidwa otulutsidwa. Gliclazide samamasulidwa kwa iwo, koma wogawana kwa maola 24. Izi zimapereka phindu pochiza matenda a shuga. Komabe, matenda ashuga sawoneka ngati chisankho choyambirira cha matenda amtundu wa 2. Ndikulimbikitsidwa kukhazikitsidwa pokhapokha ngati metformin. Werengani zomwe zikuwonetsedwa mwatsatanetsatane kuti mugwiritse ntchito, contraindication, mlingo, maubwino ndi zovuta za Diabeteson MV munkhaniyi. Dziwani zomwe mankhwalawa amatha kusintha kuti pasakhale zovulaza kuchokera ku zotsatirapo zake zoyipa.
Mapu osokoneza bongo
| Wopanga | Les Laboratoires Serviceier Industrie (France) / Serdix LLC (Russia) |
| Khodi ya PBX | A10BB09 |
| Gulu la mankhwala | Oral hypoglycemic mankhwala, sulfonylurea zotumphukira za m'badwo wachiwiri |
| Zogwira ntchito | Gliclazide |
| Kutulutsa Fomu | Mapiritsi Otulutsidwa Omasulidwa, 60 mg. |
| Kulongedza | Mapiritsi 15 okhala ndi chithuza, matuza awiri okhala ndi malangizo ogwiritsira ntchito kuchipatala adatsekedwa pakatoni. |
| Zotsatira za pharmacological | Mapiritsi amachepetsa shuga kuchokera pagulu la sulfonylurea. Yambitsani kupanga kwa insulin ndi maselo a beta a pancreatic mabungwe a Langerhans. Mankhwalawa samangowonjezera gawo lachiwiri la insulin katulutsidwe, komanso limabwezeretsa kuyambiranso kwake koyambirira chifukwa cha shuga. Komanso kumachepetsa chiopsezo cha chotupa chamagazi chotupa. Ma molekyulu a Diabeteson MV amawonetsa katundu wa antioxidant. |
| Pharmacokinetics | Kumwa mankhwalawa kamodzi patsiku kumathandizira kuti magazi azisungunuka kwambiri m'magazi oposa maola 24. Imafufutidwa makamaka ndi impso mu mawonekedwe a metabolites, ochepera 1% - ndi mkodzo wosasinthika. Okalamba, palibe kusintha kwakukulu pama paracminetic paraceter. Kudya sikukhudza kuchuluka kapena kuchuluka kwa mayamwa a gliclazide. |
| Zizindikiro zogwiritsidwa ntchito | Type 2 shuga, ngati kudya komanso kuchita masewera olimbitsa thupi sizithandiza kwenikweni. Kupewa mavuto a shuga mellitus: kuchepetsa chiopsezo cha microvascular (nephropathy, retinopathy) ndi macrovascular complication (myocardial infarction, stroke) powunika kwambiri shuga. |
| Mlingo | Mlingo woyambirira wa akuluakulu, kuphatikizapo okalamba, ndi 30 mg patsiku (piritsi 1/2). Imachulukanso kamodzi pakadutsa milungu iwiri iliyonse, ngati shuga sachepetsedwa mokwanira. Mlingo woyenera amasankhidwa mosiyanasiyana payekhapayekha, monga momwe amasonyezera shuga m'magazi komanso glycated hemoglobin HbA1C. Mlingo waukulu kwambiri ndi 120 mg patsiku. Itha kuphatikizidwa ndi mankhwala ena a shuga. Piritsi limodzi la mankhwala Diabeteson 80 mg lingathe kubwezeretsedwanso ndi piritsi la 1/2 ndikutulutsidwa kwa diabeteson MB 60 mg. Mukasamutsa odwala kuchokera ku mankhwala a Diabeteson 80 mg ku Diabeteson MB, tikulimbikitsidwa kuyeza shuga ndi glucometer kangapo patsiku, yang'anirani mosamala. Wonaninso, "Milandu Yamashuga a Magazi a Anthu Okhala Ndiathanzi." |
| Zotsatira zoyipa | Zotsatira zoyipa kwambiri ndi shuga wamagazi ochepa, hypoglycemia. Zizindikiro zake: kupweteka mutu, kutopa, kukwiya, zoopsa, kugona. Woopsa akamadwala, wodwalayo amatha kuzindikira. Werengani nkhani "Hypoglycemia - Zizindikiro, Chithandizo ndi Kupewa" mwatsatanetsatane. Diabeteson MV imayambitsa kwambiri hypoglycemia nthawi zambiri kuposa mankhwala ena - zotumphukira za sulfonylurea. Zotsatira zina zoyipa ndi kupweteka kwam'mimba, kusanza, kusanza, kutsegula m'mimba, kuyabwa, kuyabwa, kuchuluka kwa michere ya chiwindi (AST, ALT, alkaline phosphatase). Kumayambiriro kwa kutenga matenda a shuga, kumatha kusokonezeka kwakanthawi - chifukwa chakuti shuga m'magazi amatsika msanga. Hepatitis ndi jaundice ndizothekanso, koma kawirikawiri. Kusintha kwamphamvu pakapangidwe ka magazi ndizosowa kwambiri. |
| Contraindication | Diabeteson MV ndi zotumphukira zina za sulfonylurea zili ndi mndandanda waukulu wotsutsa:
Fotokozerani mosamala:
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| Mimba komanso yoyamwitsa | Diabeteson MV ndi mapiritsi ena a shuga sayenera kumwa panthawi yomwe ali ndi pakati. Ngati mukufuna kutsika magazi - chitani izi ndi zakudya komanso jakisoni wa insulin. Samalani kwambiri kuwongolera matenda ashuga panthawi ya bere kuti pasakhale zovuta kubadwa ndi kusokonezeka kwa fetal. Sizikudziwika ngati mankhwalawo amadutsa mkaka wa m'mawere. Chifukwa chake, pa mkaka wa m`mawere sichilamulidwa. |
| Kuyanjana kwa mankhwala osokoneza bongo | Mankhwala ambiri amalimbikitsa chiopsezo cha hypoglycemia ngati atengedwa ndi Diabetes. Izi ziyenera kukumbukiridwa ndi dokotala popereka chithandizo cha matenda ashuga omwe ali ndi acarbose, metformin, thiazolidinediones, dipeptidyl peptidase-4 zoletsa, agonists a GLP-1, komanso insulin. Zotsatira za Diabeteson MV zimatheka chifukwa cha mankhwala osokoneza bongo - beta-blockers ndi ACE inhibitors, komanso fluconazole, histamine H2-receptor blockers, MAO inhibitors, sulfonamides, clarithromycin. Mankhwala ena amatha kufooketsa mphamvu ya gliclazide. Werengani malangizo oyendetsedwa kuti mugwiritse ntchito mwatsatanetsatane. Uzani dokotala wanu za mankhwala onse, zowonjezera zakudya, komanso zitsamba zomwe mumamwa musanamwe mapiritsi anu a shuga. Mvetsetsani momwe mungadzipulumutsire nokha magazi. Dziwani zoyenera kuchita ngati zitakwera kapena mosinthanitsa ndizotsika kwambiri. |
| Bongo | Pogwiritsa ntchito mankhwala osokoneza bongo a sulfonylurea, hypoglycemia imayamba. Mwazi wamagazi umatsika pansi bwino, ndipo izi ndizowopsa. Hypoflycemia yofatsa imatha kuyimitsidwa yokha, ndipo m'malo ovuta kwambiri, chithandizo chachipatala chofunikira chimafunikira. |
| Kutulutsa Fomu | Mapiritsi osinthidwa osinthika ndi oyera, oval, biconvex, omwe ali ndi notch ndipo amalemba "DIA" "60" mbali zonse ziwiri. |
| Migwirizano ndi magwiritsidwe akusungidwa | Pewani kufikira ana, mikhalidwe yapadera siyofunikira. Moyo wa alumali ndi zaka 2. Osagwiritsa ntchito tsiku lotha ntchito likusonyezedwa pa phukusi. |
| Kupanga | The yogwira ndi gliclazide, 60 mg piritsi limodzi. Omwe amathandizira - lactose monohydrate, maltodextrin, hypromellose, magnesium stearate, anhydrous colloidal silicon dioxide. |
Kugwiritsa ntchito mankhwala a shuga
Mankhwala a Diabeteson mu mapiritsi amodzi ndi kumasulidwa kosinthika (MV) amaperekedwa kwa odwala omwe ali ndi matenda a shuga a 2, omwe kudya ndi kuchita masewera olimbitsa thupi samayendetsa bwino matendawa. The yogwira pophika mankhwala ndi gliclazide. Ndi m'gulu la omwe amachokera ku sulfonylurea. Gliclazide imapangitsa maselo a kancreatic pancreatic kuti apange ndikutulutsa insulin yambiri m'magazi, timadzi timene timatsitsa shuga.
Ndikulimbikitsidwa kuti muyambe kupatsa odwala 2 omwe si a Diabetes, koma mankhwala a Metformin - Siofor, Glucofage kapena Glformin. Mlingo wa metformin pang'onopang'ono umachulukitsidwa kuchokera 500-850 mpaka 2000-3000 mg patsiku. Ndipo pokhapokha ngati mankhwalawo amachepetsa shuga mosakwanira, zochokera ku sulfonylurea zimawonjezeredwa kwa iwo.
Gliclazide mapiritsi otulutsidwa otulutsidwa mosiyanasiyana kwa maola 24. Mpaka pano, machitidwe othandizira odwala matenda ashuga amalimbikitsa kuti madokotala azigwiritsa ntchito Diabeteson MV kwa odwala awo omwe ali ndi matenda a shuga a 2, m'malo mwa sulfonylureas yam'mbuyo. Mwachitsanzo, onani nkhani ya "Zotsatira za kafukufuku wa DYNASTY (" A Diabeteson MV: pulogalamu yowonera pakati pa odwala omwe ali ndi matenda a shuga 2 nthawi zonse azolowera kuchita ")" mu magazine "" Mavuto a Endocrinology "No. 5/2012, wolemba M. V. Shestakova, O K. Vikulova ndi ena.
Diabeteson MV amachepetsa kwambiri magazi. Odwala monga choncho ndiosavuta kutenga kamodzi patsiku. Amakhala otetezeka kuposa mankhwala akale - zotumphukira za sulfonylurea. Komabe, zimakhala ndi vuto, chifukwa ndibwino kuti odwala matenda ashuga asamamwe. Werengani pansipa zomwe zili ndi vuto la Diabetes, lomwe limafotokoza zabwino zake zonse. Tsamba la Diabetes-Med.Com limalimbikitsa chithandizo chamankhwala amtundu wa 2 wopanda mapiritsi owononga.
- Chithandizo cha matenda amtundu wa 2 shuga: njira ya sitepe ndi mnzake - popanda kufa ndi njala, mankhwala osokoneza bongo komanso jakisoni wa insulin
- Mapiritsi a Siofor ndi Glucofage - metformin
- Momwe mungaphunzirire kusangalala ndi maphunziro akuthupi
Ubwino ndi zoyipa
Chithandizo cha matenda a shuga a mtundu 2 mothandizidwa ndi mankhwala a shuga a MV amapatsa zotsatira zabwino pakanthawi kochepa:
- mwa odwala, shuga wamagazi amachepetsa kwambiri;
- chiopsezo cha hypoglycemia sichikupitilira 7%, chomwe ndi chotsika kwambiri poyerekeza ndi zina zomwe zimachokera ku sulfonylurea;
- ndikofunikira kumwa mankhwalawa kamodzi patsiku, kotero odwala samapereka chithandizo;
- mukumwa mankhwala a gliclazide pamapiritsi otulutsa, thupi la wodwalayo limakulitsidwa pang'ono.
Diabeteson MB yakhala mtundu wotchuka wa mankhwala ashuga a 2 chifukwa ali ndi zabwino kwa madotolo ndipo ndi abwino kwa odwala. Ndiosavuta nthawi zambiri kuti ma endocrinologists akulembere mapiritsi kuposa kulimbikitsa odwala matenda ashuga kuti azitsatira kudya komanso kuchita masewera olimbitsa thupi. Mankhwalawa amachepetsa shuga ndipo amalekeredwa bwino. Palibe oposa 1% ya odwala omwe amadandaula za zoyipa, ndipo ena onse amakhutira.
Zoyipa zamankhwala Diabeteson MV:
- Imathandizira kufa kwa maselo a pancreatic beta, chifukwa nthendayi imadutsa kwambiri matenda ashuga 1. Nthawi zambiri zimachitika pakati pa 2 ndi 8 zaka.
- Mwa anthu ochepa thupi komanso owonda, matenda ashuga omwe amadalira insulin amayamba makamaka - osachedwa kuposa zaka 2-3.
- Sizichotsa zomwe zimayambitsa matenda a shuga a 2 - kuchepa kwa chidwi kwamaselo kuti insulini. Vutoli limatchedwa insulin kukana. Kutenga Diabeteson kumatha kulimbikitsa.
- Amachepetsa shuga yamagazi, koma samachepetsa kufa. Izi zidatsimikiziridwa ndi zotsatira za kafukufuku wawukulu wapadziko lonse ndi ADVANCE.
- Mankhwalawa amatha kuyambitsa hypoglycemia. Zowona, kuthekera kwake ndikocheperako poyerekeza ndi kutengedwa kuchokera ku zinthu zina za sulfonylurea. Komabe, matenda ashuga amtundu wa 2 amatha kuyendetsedwa mosavuta popanda chiwopsezo cha hypoglycemia.
Akatswiri kuyambira zaka za m'ma 1970 amadziwa kuti kupezeka kwa matenda a shuga a 2 kumapangitsa kuti matenda ashuga amtundu woyamba akhale wovuta kwambiri. Komabe, mankhwalawa akupitilizabe kutumikiridwa. Cholinga chake ndikuti amachotsa mtolo kwa madokotala. Pakanakhala kuti palibe mapiritsi ochepetsa shuga, ndiye kuti madokotala amayenera kulemba zakudya, masewera olimbitsa thupi, ndi njira ya insulin kwa aliyense wodwala matenda ashuga. Iyi ndi ntchito yovuta komanso yosayamika. Odwala amakhala ngati ngwazi ya Pushkin: "Palibe zovuta kundinyenga, ndikusangalala kuti ndadzipusitsa." Alola kumwa mankhwala, koma sakonda kutsatira kadyedwe, masewera olimbitsa thupi, komanso makamaka jekeseni wa insulin.
Zowonongeka za Diabeteson pamaselo a beta a kapamba kwenikweni siziwakhudza endocrinologists ndi odwala awo. Palibe zolemba m'magazini azachipatala zokhudzana ndi vutoli. Cholinga chake ndikuti odwala ambiri omwe ali ndi matenda amtundu wa 2 alibe nthawi yopulumuka asanayambe matenda a shuga. Machitidwe awo a mtima ndi cholumikizira chochepa kwambiri kuposa kapamba. Chifukwa chake, amafa ndi vuto la mtima kapena sitiroko. Chithandizo cha matenda a shuga 2 omwe amachokera pakudya chamafuta ochepa nthawi imodzi amatulutsa shuga, kuthamanga kwa magazi, zotsatira za kuyesedwa kwa magazi chifukwa cha cholesterol ndi zina zomwe zimayambitsa mtima.
Zotsatira zakuchipatala
Momwe mayeso akulu azachipatala a Diabeteson MV anali kuphunzira VUTO: Chitetezo cha matenda a shuga komanso matenda a VAscular -
preterax ndi Diamicron MR Kuwongoleredwa Kuwunika. Idayambitsidwa mu 2001, ndipo zotsatira zake zidasindikizidwa mu 2007-2008. Diamicron MR - Gliclazide pamapiritsi osintha osinthika amagulitsidwa pansi pa dzinali m'maiko olankhula Chingerezi. Izi ndi chimodzimodzi ndi mankhwala a Diabeteson MV. Preterax ndi mankhwala ophatikiza matenda oopsa, zosakaniza zomwe zili indapamide ndi perindopril. M'mayiko olankhula Chirasha, amagulitsidwa pansi pa dzina la Noliprel. Phunziroli lidakhudza odwala 11,140 omwe ali ndi matenda a shuga 2 komanso matenda oopsa. Adawonedwa ndi madotolo kuzipatala 215 zamayiko 20.
Diabeteson MV imatsitsa shuga, koma siyimachepetsa kufa kwa odwala omwe ali ndi matenda ashuga a 2.
Malinga ndi zotsatira za kafukufukuyu, zidapezeka kuti mapiritsi opsinjika mwa odwala omwe ali ndi matenda a 2 amachepetsa kuchuluka kwa zovuta zamtima ndi 14%, mavuto a impso - mwa 21%, kufa - ndi 14%. Nthawi yomweyo, Diabeteson MV imachepetsa shuga m'magazi, imachepetsa kuchuluka kwa matenda a shuga ndi 21%, koma sizimakhudza kufa. Gwero la chilankhulo cha ku Russia - nkhani "Chitsogozo chothandizira odwala omwe ali ndi matenda a shuga 2: zotsatira zakufufuza" muzolemba System Hypertension No. 3/8, wolemba Yu. Karpov. Gwero loyambirira - "Gulu la Mgwirizano WABODZA. Kuwongolera kwa shuga wamagazi ndi zotumphukira zake mu odwala omwe ali ndi matenda a shuga a 2 ”mu New England Journal of Medicine, 2008, No. 358, 2560-2572.
Odwala a shuga a Type 2 amayatsidwa mapiritsi ochepetsa shuga ndi jakisoni wa insulin ngati zakudya ndi zolimbitsa thupi sizimapereka zotsatira zabwino. M'malo mwake, odwala safuna kutsatira zakudya zochepa zopatsa mphamvu. Amakonda kumwa mankhwala. Amakhulupirira kuti mitundu ina yothandiza, kupatula mankhwala ndi ma jakisoni akuluakulu a insulin, kulibe. Chifukwa chake, madokotala akupitilizabe kugwiritsa ntchito mapiritsi ochepetsa shuga omwe samachepetsa kufa. Pa Diabetes-Med.Com mutha kudziwa kuti ndizosavuta bwanji kuthana ndi matenda ashuga amtundu wa 2 popanda zakudya za "njala" ndi jakisoni wa insulin. Palibe chifukwa chomwa mankhwala oyipa, chifukwa mankhwalawa amathandizanso.
- Chithandizo cha matenda oopsa kwa odwala omwe ali ndi mtundu woyamba 1 ndi matenda ashuga 2
- Mapiritsi a Pressure Noliprel - Perindopril + Indapamide
Mapiritsi osinthidwa osinthidwa
Diabeteson MV - mapiritsi osinthidwa amasinthidwe.Chithandizo - gliclazide - chimamasulidwa kwa iwo pang'onopang'ono, osatero nthawi yomweyo. Chifukwa cha izi, yunifolomu ya gliclazide m'magazi imasungidwa kwa maola 24. Imwani mankhwalawa kamodzi patsiku. Monga lamulo, limayikidwa m'mawa. Common Diabeteson (wopanda CF) ndi mankhwala achikulire. Piritsi lake limasungunuka kwathunthu m'matumbo atatha maola awiri ndi atatu. Gliclazide yonse yomwe imakhala imalowa kulowa m'magazi. Diabeteson MV imatsitsa shuga bwino, komanso mapiritsi wamba, ndipo zotsatira zake zimatha msanga.
Mapiritsi amasinthidwe amasinthidwe amakono ali ndi phindu lalikulu pamankhwala okalamba. Chachikulu ndichakuti amakhala otetezeka. Diabeteson MV imayambitsa hypoglycemia (kutsitsidwa shuga) kangapo poyerekeza ndi Diabeton wokhazikika komanso zotumphukira zina. Malinga ndi kafukufuku, chiopsezo cha hypoglycemia sichidutsa 7%, ndipo nthawi zambiri chimadutsa popanda chizindikiro. Poyerekeza ndi pobwera kuti mupeze mtundu watsopano wamankhwala, matenda oopsa a hypoglycemia omwe ali ndi vuto losokonezeka samachitika kawirikawiri. Mankhwalawa amalekeredwa bwino. Zotsatira zoyipa zimadziwika mu zosaposa 1% za odwala.
| Mapiritsi osinthidwa osinthidwa | Mapiritsi ochita mwachangu | |
|---|---|---|
| Kangati patsiku kuti mutenge | Kamodzi patsiku | 1-2 patsiku |
| Mulingo wa Hypoglycemia | Otsika kwambiri | Pamwamba |
| Pancreatic beta cell depletion | Pang'onopang'ono | Mwachangu |
| Kulemera pang'onopang'ono | Zosafunika | Pamwamba |
Mu zolemba m'magazini azachipatala, adziwe kuti molekyulu ya Diabeteson MV ndi antioxidant chifukwa cha kapangidwe kake kapadera. Koma izi zilibe phindu lenileni, sizikhudza kuthandizira kwa chithandizo cha matenda ashuga. Amadziwika kuti Diabeteson MV imachepetsa mapangidwe amwazi m'magazi. Izi zimachepetsa chiopsezo cha stroke. Koma palibe komwe kwatsimikiziridwa kuti mankhwalawa amaperekadi zoterezi. Zofooka zakuchiritsa kwa matenda ashuga - zochokera ku sulfonylurea - zidalembedwa pamwambapa. Mu Diabeteson MV, kuchepa kumeneku sikumangotchulidwa kuposa mankhwala achikulire. Imakhudzanso pang'ono ma cell a beta a kapamba. Mtundu wa 1 wa inshuwaransi sukutuluka mwachangu.
Momwe mungamwe mankhwalawa
Mapiritsi a Diabeteson MV amayenera kumwedwa kuwonjezera pa zakudya ndi masewera olimbitsa thupi, osati m'malo mwake. Ngakhale odwala matenda ashuga ambiri amanyalanyaza malangizo azachipatala posintha moyo wabwino. Dokotalayo amakupatsani mlingo wa mankhwalawa tsiku lililonse, kutengera kuchuluka kwa shuga m'magazi. Mlingo womwe wakonzedwayo sungathe kupitilira kapena kuchepetsedwa. Ngati mutenga Diabeteson kuposa momwe amakonzera, ndiye kuti hypoglycemia imatha - shuga wochepa kwambiri. Zizindikiro zake ndi kusakwiya, manja akunjenjemera, thukuta, njala. Muzochitika zazikulu, kusazindikira ndi kufa kungachitike. Onaninso "Hypoglycemia - Zizindikiro, mankhwala, kupewa."
Diabeteson MV imatengedwa kamodzi patsiku, nthawi zambiri imakhala ndi kadzutsa. Piritsi la 60 mg losakhazikika litha kugawidwa m'magawo awiri kuti mupeze mlingo wa 30 mg. Komabe, sichitha kutafunidwa kapena kuphwanyidwa. Mukamamwa mankhwalawa, amwe ndi madzi. Webusayiti ya Diabetes-Med.Com imalimbikitsa mankhwala othandizira odwala matenda ashuga amtundu wa 2. Amakulolani kuti musiye Diabeteson, kuti musayang'anidwe ndi zovulaza zake. Komabe, ngati mumamwa mapiritsi, tsiku lililonse osapeza mipata. Popanda apo shuga amakwera kwambiri.
Kuphatikiza pa kutenga matenda a shuga, kulekerera mowa kumatha kukulirakulira. Zizindikiro zake ndi kupweteka mutu, kufupika, kupweteka kwam'mimba, mseru komanso kusanza.
Mitengo ya sulfonylureas, kuphatikiza Diabeteson MV, si mankhwala oyamba ashuga amitundu iwiri. Mosavomerezeka, ndikulimbikitsidwa kuti odwala azisankhidwa choyamba mapiritsi a metformin (Siofor, Glucofage). Pang'onopang'ono, mlingo wawo umakulitsidwa mpaka pazochulukirapo 2000-3000 mg patsiku. Ndipo pokhapokha ngati izi sizikwanira, onjezerani Diabeteson MV. Madokotala omwe amapereka mankhwala a shuga m'malo mwa metformin amalakwitsa. Mankhwalawa onse akhoza kuphatikizidwa, ndipo izi zimapereka zotsatira zabwino. Kupitilira apo, sinthani ku pulogalamu yachiwiri ya matenda ashuga kukana mapiritsi owononga.
Diabeteson MV ikhoza kuphatikizidwa ndi mapiritsi ena a shuga, kuphatikiza sulfonylureas ndi ironides (meglitinides). Wonaninso "Mankhwala a shuga a Type 2: nkhani yatsatanetsatane." Ngati Diabeteson sachepetsa shuga m'magazi, ndiye kuti muyenera kusamutsa wodwalayo kuti apange jakisoni wa insulin. Panthawi imeneyi, palibe mapiritsi ena omwe angakuthandizeni. Yambani kubayila insulini, musataye nthawi, apo ayi zovuta zovuta za shuga zidzawonekera.
Zomwe zimachokera ku sulfonylureas zimapangitsa khungu kumvetsetsa kwambiri ma radiation ya ultraviolet. Chiwopsezo chowonjezereka cha kutentha kwa dzuwa. Ndikulimbikitsidwa kugwiritsa ntchito ma sunscreens ndipo ndibwino kuti musayake ndi dzuwa. Ganizirani za chiopsezo cha hypoglycemia chomwe Diabeteson angayambire. Mukamayendetsa kapena kugwira ntchito yoopsa, yesani shuga yanu ndi glucometer mphindi 30-60 zilizonse.
Ndani sakukwanira
Diabeteson MV sayenera kumwa kwa aliyense, chifukwa njira zina zochizira matenda amtundu wa 2 zimathandiza komanso sizimayambitsa mavuto. Zoponderezedwa ndi boma zalembedwa pansipa. Dziwani kuti ndi magulu ati a odwala omwe akuyenera kupatsidwa mankhwalawa mosamala.
Pakakhala pakati komanso poyamwitsa, mapiritsi alionse ochepetsa shuga amatsutsana. Diabeteson MV siikuperekedwa kwa ana ndi achinyamata, chifukwa kugwira ntchito ndi chitetezo cha gululi sichinakhazikitsidwe. Musamamwe mankhwalawa ngati m'mbuyomu simunakhale nawo kapena mankhwala ena a sulfonylurea. Mankhwalawa sayenera kumwa ndi odwala omwe ali ndi matenda amtundu woyamba 1, ndipo ngati muli ndi vuto losakhazikika la mtundu 2 wa shuga, nthawi zambiri za hypoglycemia.
Zothandizira kuchokera ku sulfonylureas sizingatengedwe ndi anthu omwe ali ndi matenda owopsa a chiwindi ndi impso. Ngati muli ndi matenda ashuga nephropathy, lankhulanani ndi dokotala. Mwambiri, amalangizanso kulowetsa mapiritsiwo ndi jakisoni wa insulin. Kwa okalamba, Diabeteson MV ndiyoyenera ngati chiwindi chawo ndi impso zikugwira ntchito moyenera. Mosavomerezeka, zimapangitsa kusintha kwa mtundu wa 2 shuga kukhala mtundu wovuta kwambiri wa insulin wodalira inshuwaransi. Chifukwa chake, odwala matenda ashuga omwe akufuna kukhala ndi moyo wautali popanda zovuta, ndibwino kuti asamwe.
Kodi Diabeteson MV imalembedwa mosamala munthawi ziti:
- hypothyroidism - ntchito yofooka ya chithokomiro komanso kusowa kwa mahomoni ake m'magazi;
- kuperewera kwa mahomoni opangidwa ndi ma adrenal gland ndi pituitary gland;
- zakudya zosakhazikika;
- uchidakwa.
Diabeteson analogues
Mankhwala oyamba a Diabeteson MV amapangidwa ndi kampani yopanga mankhwala Laboratory Serviceier (France). Kuyambira mu Okutobala 2005, adasiya kupereka mankhwala am'mbuyomu ku Russia - mapiritsi a shuga a shuga a 80 mg. Tsopano mutha kugula kokha mapiritsi a Diabeteson MV - mapiritsi otulutsidwa amasinthidwe. Fomu ya Mlingo iyi ili ndi zabwino zake, ndipo wopanga adaganiza zokhazokha. Komabe, gliclazide pamapiritsi otulutsira mwachangu amagulitsabe. Izi ndi fanizo za Diabetes, zomwe zimapangidwa ndi opanga ena.
| Dzina lamankhwala | Kampani yopanga | Dziko |
|---|---|---|
| Glidiab MV | Akrikhin | Russia |
| Diabetesalong | Kaphatikizidwe OJSC | Russia |
| Gliclazide MV | LLC Ozone | Russia |
| Diabefarm MV | Kupanga kwama Pharmacor | Russia |
| Dzina lamankhwala | Kampani yopanga | Dziko |
|---|---|---|
| Glidiab | Akrikhin | Russia |
| Glyclazide-AKOS | Kaphatikizidwe OJSC | Russia |
| Diabinax | Moyo wa Shreya | India |
| Diabefarm | Kupanga kwama Pharmacor | Russia |
Kukonzekera komwe kaphatikizidwe kake ndi gliclazide pamapiritsi otulutsira mwachangu tsopano kwatha. Ndikofunika kugwiritsa ntchito Diabeteson MV kapena mawonekedwe ake m'malo mwake. Chabwinonso chithandizo ndi mtundu wa matenda a shuga a 2 malinga ndi zakudya zopatsa mphamvu pang'ono. Mudzatha kukhala ndi shuga wokhazikika wabwinobwino, ndipo simudzafunika kumwa mankhwala ovulaza.
Diabeteson kapena Maninil - zomwe zili bwino
Gwero la gawoli linali la mutu wakuti "Kuopsa kwa anthu wamba komanso kuwonongeka kwa mtima, komanso kuwonongeka kwamchiberekero komanso kuwonongeka kwa pachimake kwa odwala omwe ali ndi matenda a shuga 2 kutengera mtundu wa momwe angayambire mankhwala a hypoglycemic" munkhani ya "Matenda a shuga" 4 4 .9. Olemba - I.V. Misnikova, A.V. Dreval, Yu.A. Kovaleva.
Njira zosiyanasiyana zochizira matenda amtundu wa 2 zimachitika mosiyanasiyana pachiwopsezo cha matenda a mtima, stroko ndi kufa kwathunthu mwa odwala. Olemba nkhaniyi adasanthula zomwe zalembedwa mu mbiri ya anthu odwala matenda ashuga ku Moscow Region, yomwe ndi gawo la State Record of Diabetes Mellitus wa Russian Federation. Anawunika anthu omwe anapezeka ndi matenda ashuga a 2 mu 2004. Amayerekezera mphamvu ya sulfonylureas ndi metformin ngati amathandizidwa zaka 5.
Zinapezeka kuti mankhwalawa - mankhwala a sulfonylurea - ndizovulaza kuposa zothandiza. Momwe amathandizira poyerekeza ndi metformin:
- chiopsezo cha kufa ndi mtima - kawiri;
- chiwopsezo cha mtima - chachulukitsidwa ka 4,6;
- chiopsezo cha kumenyedwa chinakulitsidwa katatu.
Nthawi yomweyo, glibenclamide (Maninil) inali yovulaza kuposa gliclazide (Diabeteson). Zowona, nkhaniyi sichinatchule kuti ndi a Manilil ndi a Diabeteson omwe amagwiritsidwa ntchito - mapiritsi otha kuchepetsedwa kapena wamba. Zingakhale zosangalatsa kuyerekezera zomwe zimachitika ndi odwala omwe ali ndi matenda amtundu wa 2 omwe adalandira mankhwala a insulin m'malo mwa mapiritsi. Komabe, izi sizinachitike, chifukwa odwala oterowo sanali okwanira. Ambiri mwa odwala amakanika jakisoni jakisoni, motero anapatsidwa mapiritsi.
Mafunso Ofunsidwa Kawirikawiri
A Diabetes adawongolera matenda amtundu wa 2 bwino kwa zaka 6, ndipo tsopano asiya kuthandiza. Anawonjezera mlingo wake mpaka 120 mg patsiku, koma magazi a magazi akadali okwera, 10-12 mmol / l. Chifukwa chiyani mankhwalawa alephera? Kodi atichitira chiyani tsopano?
Diabetesone ndi wochokera ku sulfonylurea. Mapiritsiwa amachepetsa shuga m'magazi, komanso amakhala ndi zovulaza. Pang'onopang'ono amawononga maselo a pancreatic beta. Pambuyo pa zaka 2-9 pakuwatenga odwala, thupi limayamba kusowa kwenikweni. Mankhwalawa alephera kugwira ntchito chifukwa maselo anu a beta "atha." Izi zikanachitika kale. Kodi atichitira chiyani tsopano? Kufunika kubaya insulin, palibe njira. Chifukwa muli ndi matenda ashuga amtundu wa 2 adasanduka mtundu waukulu wa shuga. Patani diabeteson, sinthani ku chakudya chochepa chamafuta ndipo mupeze insulin yambiri kuti mukhale shuga wabwinobwino.
Wachikulire wakhala akudwala matenda ashuga amtundu wa 2 kwa zaka 8. Shuga wamagazi 15-17 mmol / l, zovuta zopangidwa. Adatenga manin, tsopano adasamukira ku Diabeteson - sizinaphule kanthu. Kodi ndiyambe kumwa amaryl?
Zomwezo ngati wolemba wa funso lakale. Chifukwa chazaka zambiri zosachiritsika bwino, mtundu 2 wa matenda ashuu wasintha kukhala mtundu waukulu wa shuga. Palibe mapiritsi omwe angapatsidwe. Tsatirani pulogalamu ya matenda a shuga 1, yambani kubayila insulin. Zochita, nthawi zambiri zimakhala zosavuta kukhazikitsa chithandizo choyenera cha odwala matenda ashuga. Ngati wodwalayo akuiwalika komanso kukhala wokhazikika - siyani chilichonse monga momwe ziliri ndikuyembekezera modekha
Kwa matenda a shuga a 2, adokotala adandiuza 850 mg tsiku lililonse kwa Siofor. Pambuyo pa miyezi 1.5, adasamukira ku Diabeteson, chifukwa shuga sizidagwere konse. Koma mankhwalawa ndiwothandizanso. Kodi ndizoyenera kupita ku Glibomet?
Ngati Diabeteson satsitsa shuga, ndiye kuti Glibomet sikhala othandiza. Mukufuna kuchepetsa shuga - yambani kubayila insulini. Pankhani ya matenda apamwamba a shuga, palibe njira yina yomwe ingapezeke. Choyamba, sinthani ku chakudya chochepa chamafuta ndikuleka kumwa mankhwala owononga. Komabe, ngati mwakhala muli ndi mbiri yakale ya matenda ashuga amtundu wa 2 ndipo mwathandizidwa molakwika pazaka zapitazi, ndiye kuti muyenera kuperekanso insulin. Chifukwa chakuti kapamba amatayika ndipo sangathe kupirira popanda kuthandizidwa. Zakudya zama carb zotsika zimachepetsa shuga, koma osazolowera. Kuti mavutowa asadzayambike, shuga sayenera kupitirira 5.5-6.0 mmol / l 1-2 patatha chakudya komanso m'mawa pamimba yopanda kanthu. Phatikizani pang'onopang'ono insulini pang'ono kuti mukwaniritse izi. Glibomet ndi mankhwala ophatikiza. Zimaphatikizapo glibenclamide, yomwe imakhala ndi zovulaza zofanana ndi Diabetes. Osagwiritsa ntchito mankhwalawa. Mutha kutenga "pure" metformin - Siofor kapena Glyukofazh. Koma palibe mapiritsi omwe angalowe m'malo mwa jakisoni wa insulin.
Kodi ndizotheka kuti matenda a shuga a mtundu wachiwiri atenge Diabeteson ndi sapxin kuti achepetse thupi nthawi yomweyo?
Momwe diabeteson ndi sapxin zimalumikizirana - palibe deta. Komabe, Diabetes imalimbikitsa kupanga insulin ndi kapamba. Insulin, nayenso, imasintha shuga kukhala mafuta ndikulepheretsa kuchepa kwa minofu ya adipose. Mokulira kwambiri m'magazi, zimakhala zovuta kwambiri kuchepetsa thupi. Chifukwa chake, odwala matenda ashuga ndi othandxin amakhala ndi zotsutsana. Reduxin amayambitsa mavuto ambiri ndipo chizolowezi chake chimayamba msanga. Werengani nkhani ya "Momwe mungachepetse thupi ndi matenda ashuga a 2." Siyani kumwa Diabeteson ndi sapxin. Sinthani ku chakudya chochepa chamafuta. Amasintha shuga, kuthamanga kwa magazi, cholesterol m'magazi, ndipo mapaundi owonjezera amathanso.
Ndakhala ndikutenga Diabeteson MV kwa zaka 2 kale, kuthamanga shuga kumakhalabe pafupifupi 5.5-6.0 mmol / l. Komabe, chidwi choyaka m'mapazi chayamba posachedwa ndipo mawonekedwe akutsika. Chifukwa chiyani zovuta za matenda ashuga zimayamba ngakhale shuga ndi abwinobwino?
Ndikofunikira kuti muchepetse shuga pakatha maola awiri mutatha kudya komanso m'mawa pamimba yopanda kanthu. Magawo a shuga musanadye nkhomaliro komanso chakudya chamadzulo ndizofunikira. Odwala ambiri omwe ali ndi matenda a shuga a 2, kuthamanga kwa shuga ndikwabwino. Komabe, mavuto amakula ngati magazi a m'magazi amatuka kwa maola angapo nthawi iliyonse atadya. Kuyeza shuga pamimba yopanda kanthu ndikusayang'ananso maola 1-2 mutatha kudya ndikudzinyenga nokha. Muyenera kulipira chifukwa cha zovuta za matenda ashuga. Onaninso - miyezo ya shuga ya magazi kwa anthu athanzi komanso odwala matenda ashuga.
Dotolo adayikira Diabeteson kuti akhale ndi shuga wambiri, komanso zakudya zochepa zama calorie komanso zosakoma. Koma sananene kuti angachepetse kuchuluka kwa zopatsa mphamvu. Ngati ndimadya zopatsa mphamvu 2000 patsiku, ndiye kuti sizachilendo? Kapena mukufunanso zochepa?
Zakudya zanjala zimathandiza kuchepetsa shuga m'magazi, koma machitidwe, ayi. Chifukwa odwala onse amamuthawa. Palibe chifukwa chokhalira ndi njala! Phunzirani ndikutsatira pulogalamu yachiwiri yothandizira odwala matenda ashuga. Sinthani ku chakudya chochepa chamafuta - chimakhala chokoma, chopatsa komanso chotsika shuga. Lekani kumwa mapiritsi owononga. Ngati ndi kotheka, jekeseni insulini ingapo. Ngati vuto lanu la shuga silikuyenda, ndiye kuti mutha kusunga shuga wabwinobwino popanda jakisoni.
Ndimatenga Diabeteson ndi Metformin kuti ndikalipire T2DM yanga. Mwazi wamagazi umagwira 8-11 mmol / L. The endocrinologist akuti izi ndi zotsatira zabwino, ndipo zovuta zanga zaumoyo zimayenderana ndi zaka. Koma ndikuwona kuti zovuta za shuga zikukula. Ndi chithandizo chiti chothandiza kwambiri chomwe mungalimbikitse?
Shuga wabwinobwino wamagazi - monga mwa anthu athanzi, osapitilira 5.5 mmol / l mutatha 1 ndi maola awiri mutadya. Nthawi zonse, matenda a shuga amakula. Kuchepetsa shuga lanu kukhala labwinobwino komanso kukhala lokhazikika, werengani ndikutsatira pulogalamu yachiwiri yothandizira anthu odwala matenda ashuga. Ulalo wa icho umaperekedwa poyankha funso lapita.
Dokotala adalamula kuti atenge Diabeteson MV usiku, kotero kuti panali shuga wabwinobwino m'mimba yopanda kanthu. Koma malangizowo akuti muyenera kumwa mapiritsiwa kuti mudye chakudya cham'mawa. Ndiyenera kukhulupirira ndani - malangizo kapena malingaliro a dokotala?
Muyenera kuchita kanthu usiku kuti shuga akhale bwino m'mawa wotsatira. Dokotala wanu akunena izi :). Koma kumwa matenda a Diabetes ndi lingaliro loipa, chifukwa awa ndi mapiritsi owononga. Zomwe mungasinthe ndikulongosola mwatsatanetsatane. Onaninso "Momwe mungapangire shuga m'mawa." Ngati mukufuna kupaka insulin yayitali kwa nthawi yayitali usiku - ichite, musakhale aulesi.
Wodwala wodwala matenda ashuga a 2 omwe ali ndi zaka 9, zaka 73. Shuga amakwera mpaka 15-17 mmol / l, ndipo manin samatsitsa. Anayamba kuchepa thupi kwambiri. Kodi ndiyenera kupita ku Diabeteson?
Ngati mannin satsitsa shuga, ndiye kuti palibe lingaliro kuchokera kwa Diabetes. Ndinayamba kuchepa thupi kwambiri - zomwe zikutanthauza kuti palibe mapiritsi omwe angathandize. Onetsetsani kuti mwabaya insulin. Matenda othamanga 2 a shuga asintha kukhala matenda ashuga amtundu woyamba, kotero muyenera kuphunzira ndikukhazikitsa pulogalamu yothandizira matenda a shuga 1. Ngati sizotheka kukhazikitsa jakisoni wa okalamba wodwala matenda ashuga, siyani zonse momwe ziliri ndikuyembekezera modekha. Wodwalayo amakhala ndi moyo wautali ngati atathetsa mapiritsi onse a shuga.
Ndemanga za Odwala
Anthu akayamba kumwa diabetes, shuga wawo wamagazi amatsika mofulumira. Odwala amadziwa izi pakuwunika kwawo. Mapiritsi osinthidwa osinthidwa nthawi zambiri samayambitsa hypoglycemia ndipo nthawi zambiri amalekeredwa bwino. Za mankhwala a Diabeteson MV palibe kubwereza komweko komwe wodwala matenda ashuga amadandaula ndi hypoglycemia. Zotsatira zoyipa zokhudzana ndi kufinya kwam'mimba sizimakhazikika nthawi yomweyo, koma patatha zaka 2-8. Chifukwa chake, odwala omwe ayamba kumwa mankhwalawa posatchulapo.
Oleg Chernyavsky
Kwa zaka 4 ndakhala ndikumwa piritsi la Diabeteson MV 1/2 m'mawa nthawi yam'mawa. Chifukwa cha izi, shuga imakhala yabwinobwino - kuyambira 5.6 mpaka 6.5 mmol / L. M'mbuyomu, idafika 10 mmol / l, mpaka idayamba kuthandizidwa ndi mankhwalawa. Ndimayesetsa kuchepetsa maswiti ndikudya moyenera, monga momwe dokotala adalangizira, koma nthawi zina ndimatsika.
Mavuto a shuga amabwera pamene shuga amasungidwira maola angapo chakudya chikatha. Komabe, kusala kwama glucose osala kudya kungakhale kwabwinobwino. Kuwongolera shuga osala kudya komanso osayeza ngati maola 1-2 mutatha kudya ndi kudzinyenga nokha. Muwalipira ndikuwoneka koyambirira kwa zovuta zovuta. Chonde dziwani kuti miyezo ya shuga ya magazi kwa anthu odwala matenda ashuga ndiochuluka. Mwa anthu athanzi, shuga atatha kudya sakwera pamwamba pa 5.5 mmol / L. Muyeneranso kuyesetsa kuzizindikira, osamvetsera nthano zomwe shuga itatha kudya 8-11 mmol / l ndiyabwino kwambiri. Kukwaniritsa kuyendetsa bwino shuga.
Svetlana Voitenko
Dokotala wa endocrinologist adandiuza kuti ndikhale ndi matenda ashuga, koma mapiritsiwa amangokulitsa. Ndakhala ndikutenga kwa zaka ziwiri, nthawi iyi ndidasanduka munthu wokalamba kwenikweni. Ndataya 21 kg. Masomphenya amagwa, khungu limakhala lakuwona pamaso, mavuto ndi miyendo idawonekera. Mwazi umakhala wowopsa kuyeza ndi glucometer. Pepani matenda ashuga amtundu wa 2 asintha kukhala mtundu waukulu wa matenda ashuga.
Odwala onenepa kwambiri omwe ali ndi matenda a shuga a 2, zotumphukira za sulfonylurea zimathetsa kapamba, makamaka pambuyo pa zaka 5-8. Tsoka ilo, anthu owonda komanso owonda amachita izi mwachangu kwambiri. Phunzirani nkhani yokhudza matenda a shuga a LADA ndikuyesa mayeso omwe alembedwamo. Ngakhale ngati pali kuchepa kwamphamvu kwa thupi, ndiye kuti popanda kusanthula zonse zili zomveka ... Phunzirani pulogalamu ya chithandizo cha matenda a shuga 1 ndikutsatira malangizowo. Patulani diabeteson yomweyo. Jakisoni wa insulin ndi ofunika, simungathe popanda iwo.
Andrey Yushin
Posachedwa, dotolo yemwe adalipo adandiwonjezera piritsi limodzi la 2/2 la metformin kwa ine, lomwe ndidali nditagula kale. Mankhwala atsopanowa adayambitsa vuto la atypical - zovuta m'mimba. Nditatha kudya, ndimamva kuwawa m'mimba mwanga, kutulutsa, nthawi zina kutentha. Zowona, kulakalaka kunagwa. Nthawi zina simumamvanso ludzu, chifukwa m'mimba mwadzaza kale.
Zizindikiro zomwe zimafotokozeredwa sizotsatira zoyipa za mankhwalawa, koma zovuta za matenda a shuga otchedwa gastroparesis, gawo la ziwopsezo zam'mimba. Imachitika chifukwa cha kuwonongeka kwa mitsempha yomwe imalowa mu kayendedwe kazinthu zamagetsi ndikuwongolera chimbudzi. Ichi ndi chimodzi mwamawonekedwe a matenda am'mimba. Njira zapadera ziyenera kuchitidwa motsutsana ndi izi. Werengani nkhani yomwe "Diabetesic gastroparesis" mwatsatanetsatane. Zimasinthidwa - mutha kuzichotsa kwathunthu. Koma chithandizo ndimavuto ambiri. Zakudya zamafuta ochepa, masewera olimbitsa thupi, komanso jakisoni wa insulin zimathandizira kuti shuga azingokhala pokhapokha ngati m'mimba mwanu likugwira ntchito. Matenda a shuga ayenera kuchotsedwa, monga onse odwala matenda ashuga, chifukwa ndi mankhwala owopsa.
Mapeto
Pambuyo powerenga nkhaniyi, mudaphunzira zonse zomwe mukufuna pa mankhwala a Diabeteson MV. Mapiritsi awa mwachangu komanso mwamphamvu amachepetsa shuga ya magazi. Tsopano mukudziwa momwe amachitira izi. Zafotokozedwera mwatsatanetsatane momwe Diabeteson MV imasiyanirana ndi zomwe zimachokera m'mibadwo yam'mbuyomu. Muli ndi maubwino, koma zovuta zake zimapezekabe. Ndikofunika kuti musinthane ndi mtundu wachiwiri wa chithandizo cha matenda ashuga kukana kumwa mapiritsi owononga. Yesani zakudya zamafuta ochepa - ndipo patatha masiku atatu mutha kuwona kuti mutha kusunga shuga wabwinobwino. Palibe chifukwa chofunikira kutengera zochokera ku sulfonylurea ndikuvutika ndi zovuta zake.
