INSULIN YOCHEPA - NDI CHIYANI? - NJIRA NDI NJIRA ZOCHIRITSIRA

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Insulin yochita ntchito mwachidule ndi njira yochepetsera shuga yomwe imayendetsa kagayidwe kake m'thupi.

Kuphatikizika kwa mankhwalawa kumaphatikizapo yankho loyera la mahomoni, lomwe mulibe zina zowonjezera zomwe zimathandizira thupi. Gulu la ochita zinthu mwachidule limachita zinthu mwachangu kuposa ena, koma nthawi yonse yomwe ntchito zawo ndi zazifupi.

Mankhwala osokoneza bongo amapezeka mu Mbale zagalasi losindikizidwa, losindikizidwa ndi zoletsa ndi ma aluminium processing.

Zotsatira za insulin yochepa m'thupi limodzi ndi:

kuponderezana kapena kusangalatsa kwa michere ina;
kutsegula kwa glycogen kaphatikizidwe ndi hexokinase;
kuponderezedwa kwa lipase yothandizira mafuta acids.

Mlingo wa secretion ndi biosynthesis zimadalira kuchuluka kwa shuga m'magazi. Ndi kuwonjezeka kwa msinkhu wake, njira zopangira insulin mu kapamba zimachulukirachulukira, komanso, ndikachepa ndende, kutulutsidwa kumachepetsa.

Gulu Lachidule la Insulin

Malinga ndi nthawi ya insulin yocheperako ndi:

Pofupikitsa (sungunuka, oyang'anira) insulin - chitani pambuyo pakatha theka la ola, motero amalimbikitsidwa kuti azigwiritsidwa ntchito mphindi 40-50 musanadye. Tizilombo tambiri tomwe timagwira mu mtsinje wamagazi timafika patatha maola awiri, ndipo titatha maola 6 okha mankhwalawa amatsalira m'thupi. Zovala zazifupi zimaphatikizira mafuta osungunuka amtundu wa anthu, mafuta osungunuka a semisynthetic ndi nkhumba zosungunulira zina zosungunulira.
Ultrashort (waumunthu, wa analog) wosungira - ayambe kusokoneza thupi pambuyo pakatha mphindi 15. Zochita zapamwamba zimapezekanso patatha maola angapo. Kuchotsa kwathunthu kwa thupi kumachitika pambuyo pa maola anayi. Chifukwa chakuti ultrashort insulin imakhudzanso zolimbitsa thupi, kukonzekera komwe amapezeka kumatha kugwiritsidwa ntchito mphindi 5-10 musanadye kapena mukangodya. Mtundu wa mankhwalawa umaphatikizapo ma insulin ndi insulin yopanga anthu.

Tiyenera kudziwa kuti insulini ya ultrafast imafanana ndi masoka amthupi la munthu ndikukula kwa shuga wamagazi atatha kudya. Chifukwa chake amayenera kumwedwa nthawi yochepa asanadye kapena akangomaliza kudya.

Insulin yochepa ya shuga

Matenda a shuga amathandizira kupewa kukula kwa zovuta, kutalikitsa moyo wa anthu odwala matenda ashuga ndikuwongolera. Komanso, jakisoni wa mankhwalawa amachepetsa katundu pa kapamba, zomwe zimapangitsa kubwezeretsa pang'ono kwa maselo a beta.

Zoterezi zimatheka ndi mtundu wachiwiri wa matenda a shuga ndikukhazikitsa pulogalamu yoyenera ndikutsatira dongosolo lomwe dokotala walimbikitsa. Kubwezeretsanso kwa ma cell a beta ndikothekanso ndi matenda a mtundu woyamba 1 pokhapokha ngati matendawo awupeza munthawi yake ndipo njira zamankhwala zimatengedwa mwachangu.
Nthawi zambiri, mankhwalawa amathandizidwa ndi intramuscularly kapena subcutaneally ndi syringe yopangidwa mwapadera. Pokhapokha ngati wodwala matenda ashuga, mtsempha wa magazi amaloledwa. Mlingo wake umasankhidwa payekhapayekha, poganizira kuopsa kwa matendawa, kuchuluka kwa shuga mthupi ndi momwe wodwalayo alili.

Jakisoni wa insulin amayikidwa pa Mlingo wa 2-3 patsiku theka la ola musanadye. Mlingo wamba wa mankhwalawa umachokera kwa 10 mpaka 40 magawo patsiku.

Ndi chifuwa cha matenda ashuga, kuchuluka kwakukulu kwa mankhwalawa kumafunikira: kwa makina osokonekera - kuchokera ku 100 PIECES, komanso kwa oyang'anira amkati - mpaka 50 PIECES patsiku. Pochiza matenda amishuga a shuga, kuchuluka kwa insulini kumawerengeredwa molingana ndi kuopsa kwa matenda oyambitsidwa. Nthawi zina, kuchuluka kwa ma horoni sikofunikira, tikulimbikitsidwa kuyambitsa milingo yaying'ono, koma nthawi zambiri.

Zochita Zosiyana ndi Zopikisana

Insulin SIYONSE kuti igwiritsidwe ntchito ndi:

kapamba
chiwindi
yade

matenda amtima owala,
matenda a impso
zilonda zam'mimba zam'mimba komanso duodenum.

Zotsatira zoyipa pambuyo pokhazikitsidwa ndi mahomoni wothandizila zimachitika pamene mulingo wotsatira osatsatiridwa. Izi zimaphatikizidwa ndi kuwonjezeka kwakukulu kwa insulin mumtsinje wamagazi.

Zotsatira zoyipa kwambiri ndizophatikizirapo:

kufooka kwathunthu;
thukuta;
palpitations
kuchuluka kwa masokosi;
chizungulire.

Milandu yakukwera kwambiri kwa mahomoni m'mitsempha yamagazi (ngati sipangakhale chakudya chamakanika panthawi yake), kukomoka kumatha kuchitika, komanso kumatha kukhala chikumbumtima komanso chikomokere.

Kukonzekera kwapafupipafupi komanso kopambana

Mankhwala onse omwe amakhala ndi ma insulin amtundu wa anthu kapena mawonekedwe awo ali ndi zofanana. Chifukwa chake, ngati kuli kotheka, zitha kusinthidwa, ndikuwona mlingo womwewo, ndi kufunsa kwa adokotala ndikofunikira. Chifukwa chake, kusankha kochepa kwa maina a insulin omwe amangokhala mwachangu komanso mwachangu

Wotchuka kwambiri komanso mankhwala kuchita mwachidule ndi:

Actrapid (mtengo wapakati pama ruble 380)

- opangidwa pogwiritsa ntchito Saccharomyces cerevisiae pogwiritsa ntchito ukadaulo wa DNA. Kutalika kwa kachitidwe ka zinthu zogwirira ntchito pa thupi kumatsimikiziridwa ndi kuyamwa kwake. Zimatengera Mlingo, dera, mtundu wa shuga ndi njira yoyendetsera. Mphamvu ya mankhwalawa imayamba patatha mphindi 30 jekeseni. Kuchuluka kwa insulin kumatheka pambuyo pa nthawi yofanana ndi maola 1.5-3,5 ndipo nthawi ya zochita zake imasiyana maola 7 mpaka 8.

Humulin (mtengo 5 ruble)

- mankhwala ndi hypoglycemic kwenikweni. Amapangidwa pamaziko a biosynthetic insulin yaumunthu ndipo amakhudzana ndi mahomoni ogwiritsira ntchito nthawi yochepa kapena yapakatikati. Mankhwalawa amayamba kugwira ntchito ukatha ola limodzi. Kuzindikira kwakukulu kumatheka pambuyo pa maola 1-3, ndipo nthawi yonse yokhala m'thupi ndi maola 5-8.

Iletin (mtengo wapakatikati kuchokera ku ma ruble 400)

- kapangidwe kake ka mankhwalawa amaphatikiza insulin-zinc pork monocomponent. Mankhwalawa amakhala ndi nthawi yayifupi komanso yapakatikati, chifukwa cha kuyamwa kwa zinthu zomwe zimagwira. Kukhazikika kwa kuwonekera kwa mankhwalawa kumachitika pambuyo pa maola a 2,5, ndipo mphamvu yayikulu imachokera ku maola 7 mpaka 15. Zitulo za insulin zimachotsedwa m'thupi tsiku limodzi pambuyo pake.

Kukonzekera kwa Ultrafast:

Novorapid (mtengo 1700 rub.)

- opangidwa pogwiritsa ntchito Saccharomyces cerevisiae ndi amino acid m'malo ndi Aspartic acid. Kutalika kwa mankhwalawa ndi kochepa kwambiri kuposa komwe kumapangitsa kuti insulini isungunuke. Pambuyo pa utsogoleri, ntchito yake imayamba pakadutsa mphindi 10-20. Mulingo wokwanira m'magazi umafikiridwa pambuyo pa maola 1-3. Chochitikacho chimatha jakisoni kwa maola atatu kapena asanu.

Humalog (mtengo wokwanira pa cartridge 550 ruble)

- Analogue ya insulin yaumunthu, yodziwika ndikuyamba mwachangu komanso kutha kwa ntchito poyerekeza ndi mankhwala osokoneza bongo. Kuthamanga kwa zotsatira zake kumachitika chifukwa cha mapangidwe a monomeric a mamolekyulu a humalogue. Pambuyo pa jakisoni, wothandizirana ndi mahomoni amayamba kukhudza thupi la munthu pakatha mphindi 15. Tizilombo totsimikizika timawonedwa patatha mphindi 30 kapena maola 2,5. Imapukutidwa pambuyo pa maola 3-4.

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