Mapiritsi a Oral Tricor onse a 145 ndi 160 mg amapangidwa ndi chinthu chogwira ntchito monga fenofibrate.
Ponena za pharmacological kanthu, ndi lipid-kutsitsa (kapena kutsitsa ndende ya lipids). Mankhwala ndi a gulu la zamankhwala ena.
Makhalidwe wamba
Kwenikweni, mankhwalawa amagwiritsidwa ntchito pa pathologies omwe amagwirizanitsidwa ndi:
- ndi ma insulin onse omwe amadalira insulin komanso osadalira insulin;
- ndi hypercholesterolemia (cholesterol yayikulu m'magazi), hyperglyceridemia (triglyceridides yambiri;
- ndi hyperlipidemia yosakanikirana (kuthamanga kwa magazi kwa cholesterol komanso mafuta, komanso triglyceride);
- komanso ndi hyperlipidemia ina.
Zambiri za umembala wa Tricor mu gulu linalake lazachipatala ndi zamankhwala, opanga amalamula kuti Recipharm Monts, komanso Laboratoies Fournier S.A. sikuti kulibe.
Pharmacological zochita ndi zikuwonetsa
Panthawi ya mayeso a mankhwala a Tricor mwachindunji m'zipatalazi, kafukufuku pa odwala adawonetsa kuti mothandizidwa ndi fenofibrate, kuchuluka kwa cholesterol kwathunthu kwa odwala kumachepetsedwa ndi 20, kapena ngakhale onse 25%, ndipo pokhudzana ndi kutsitsa kwawo triglycerides, chizindikiro ichi chimachokera ku 40 mpaka 55%.
Mapiritsi Tricor 145 mg
Komanso, odwala hypercholesterolemia, chiŵerengero cha okwanira ndi LDL cholesterol amachepetsa. Tiyenera kukumbukira kuti chiwerengerochi ndi chimodzi mwazomwe chimawonjezera chiopsezo cha matenda a mtima.
Mankhwala chikuwonetsedwa ngati cholowerera kuchiza kosagwiritsidwa ntchito ndi mankhwala. Kwa masewera olimbitsa thupi osiyanasiyana, njira zolemetsa, komanso kugwiritsa ntchito zakudya zamagulu:
- kwambiri hypertriglycemia;
- hyperlipidemia yosakanikirana, ngati pali contraindication a statins (mankhwala omwe amachepetsa cholesterol m'magazi);
- Hyperlipidimia wosakanikirana. Odwala akakhala ndi chiopsezo cha mtima komanso misempha yonse;
- komanso miyala mapiritsi amalembedwera pamaso pa matenda a shuga makamaka ngati zakudya ndi zolimbitsa thupi sizingatheke.
Zochizira
Fenofibrate ndi chinthu chomwe chimachokera ku fibric acid. Amasintha chiŵerengero cha lipids m'magazi.
Pa mankhwala, zosintha zotsatirazi zimawonedwa:
- chilolezo chowonjezereka kapena kuyeretsa magazi;
- mwa odwala omwe ali ndi chiopsezo cha CHD, kuchuluka kwa atherogenic lipoproteins kumachepera (ratio, yomwe imawonjezera chiopsezo cha atherosulinosis) kapena "cholesterol" yoyipa;
- amalimbikitsa kuwonjezeka kwa cholesterol "yabwino";
- kuthekera kwa intravascular deposits kumachepetsedwa kwambiri;
- mulingo wa fibriogen umachepa;
- magazi amachepetsa zomwe zimapanga uric acid, komanso mapuloteni C omwe amathandizira m'magazi ake.
Zambiri zomwe zimapangitsa fenofibrate m'magazi zimachitika patangopita maola angapo mutatenga wodwala Tricor.
Imapukutidwa kwathunthu mkati mwa masiku 6-7 makamaka ndi mkodzo. Nthawi yomweyo, fenofibrate sinafukusidwa panthawi ya hemodialysis, chifukwa chikuwoneka kuti ndi chomangika kwambiri ku plasma albumin (puloteni yayikulu).
Contraindication
Mndandanda wazopondera zomwe zidadziwika pofufuza, komanso chifukwa chogwiritsa ntchito Treycor, ndi motere:
- kuchuluka kwa chidwi chokwanira ndi thupi kupanga fenofibrate, komanso magawo ena a mankhwalawa;
- hepatic, aimpso kulephera;
- matenda a chiwindi;
- zaka zosakwana 18;
- photosensitivity (kuchuluka kwa chidwi cha mucous nembanemba ndi khungu ku ma ultraviolet komanso mawonekedwe a radiation), komanso Phototoxicity;
- matenda a ndulu;
- mawonetseredwe a ziwengo kwa mtedza ndi mafuta ake, ku zinthu za soya, zomwe zimawululidwa pokonzekera ma anamnesis kapena kufunsa wodwala asanapereke mankhwala;
- kuyamwa.
Mosamala, Tricor amamuika wodwala:
- amamwa mowa;
- akudwala hypothyroidism kapena kuchepa kwa mahomoni a chithokomiro;
- mu kukalamba;
- ali ndi matenda obadwa nawo a minofu.
Mimba
Zambiri za mayesero azachipatala komanso momwe mungagwiritsire ntchito mankhwalawa ndi amayi apakati, sikokwanira.
Mwachitsanzo, pakuyesera ndi nyama, tetratogenic zotsatira (kukula kwa mluza pansi pa mphamvu ya mankhwala) sizinapezeke.
Kuphatikiza apo, pakumayesedwa koyesa, embryotoxicity idawonetsedwa chifukwa chogwiritsidwa ntchito ndi m'modzi mwa amayi apakati omwe ali ndi mlingo waukulu wa mankhwalawo. Komabe, chiwopsezo kwa amayi oyembekezera sichinadziwikebe kwathunthu.
Mlingo ndi Madeti
Mankhwala amatengedwa pakamwa, ndikutsuka piritsi ndi madzi. Nthawi yodyetsera imakhala yotsutsana ndipo sizidalira chakudyacho (Tricor 145). Kulandila kwa Tricorr 160 kuyenera kuchitika nthawi yomweyo ndi chakudya.
Mlingo wa odwala ndi piritsi limodzi patsiku.
Kuphatikiza apo, ngati odwala adatenga piritsi la ma milligram 160 a Tricor, atha, ngati kuli kotheka, amasinthana ndi kutenga ma milligram a 145 a mankhwalawo, komanso osasintha mlingo. Odwala okalamba ayenera kumwa muyezo - osapitirira 1 piritsi tsiku limodzi.
Mankhwalawa amakhala ndi nthawi yayitali yogwiritsira ntchito, pomwe muyenera kutsatira zakudya zomwe mumayambitsa kale. Kuwunikira kwa mphamvu ya Tricoror chithandizo kuyenera kuchitika kokha ndi adokotala popenda zomwe lipids zonse ziwiri (mafuta ndi zinthu zomwe zimafanana naye), ndi LDL, cholesterol yathunthu, komanso zomwe zili triglycerides.
Mlanduwo ngati kwa miyezi ingapo achire sichikuwoneka, ndiye kuti njira zina zochiritsidwira ziyenera kuganiziridwanso.
Zochita Zamankhwala
Fenofibrate ikaphatikizidwa ndi anticoagulants mkamwa (mankhwala omwe amachotsa thrombosis) imathandizira zotsatira zamatsenga mpaka pachiwopsezo chowonjezereka cha magazi, chifukwa chakuti mankhwala opatsirana a antithrombotic nthawi zambiri amachotsedwa pamasamba omwe amakhala ndi mapuloteni omanga ku plasma ya magazi.
Chifukwa chake, kumayambiriro kwa mankhwalawa ndi fenofibrate, munthu ayenera kuchepetsa kuchuluka kwa mankhwalawa ndi gawo limodzi mwa magawo atatu kenako ndi kusankha pang'onopang'ono mlingo woyenera molingana ndi mulingo wa INR (kuchuluka kwa mitundu yonse). Momwe mungagwiritsire ntchito molumikizana ndi mankhwala monga cyclosporine, mumakhala zochitika zingapo zovuta za kayendedwe kake limodzi ndi fenofibrate.
Ngati izi ndizofunikira, ndiye kuti ziyenera kuyang'anira ntchito za chiwindi, ndikusintha koopsa pazomwe zimawunikira zikuwoneka, nthawi yomweyo chotsani Tricor. Odwala omwe apezeka ndi hyperlipodemia, amatenga mankhwala a mahomoni kapena njira zakulera, ayenera kudziwa mtundu wa matenda awa, chifukwa amatha kukhala a mtundu woyamba kapena wachiwiri.
Ponena za mtundu wachiwiri wa matenda, amatha chifukwa cha kudya kwa estrogen, komwe nthawi zina kumatsimikiziridwa ndi anamnesis kapena kufunsa kwa odwala.
Nthawi zina, pogwiritsidwa ntchito ndi Tricor ndi mankhwala ena, kuwonjezeka kwa transaminase (awa ndi ma enzymes mkati mwa cell omwe amasamu molekyulu amino acid amawonekera m'chiwindi.
Nthawi yomweyo, pali mafotokozedwe azovuta zokhudzana ndi kutenga Tricor mu mawonekedwe a kapamba. Njira zotupa izi zimagwirizanitsidwa onse ndi kuthamanga kwa mankhwalawa, komanso kupezeka kwa miyala kapena mapangidwe amtundu wofanana ndi mawonekedwe olimba mu ndulu, zomwe zimasokoneza magwiridwe antchito a ndulu ya bile.
Odwala omwe amakonzedweratu ku myopathy (cholowa chamtundu wa minofu), komanso omwe ali ndi zaka zoposa 70, akhoza kukhala ndi mawonekedwe a rhabdomyolysis (matenda owonongera maselo a minofu) chifukwa cha zotsatira za fenofibrate.
Cholinga cha mankhwalawa chimangokhala chokhacho pomwe zotsatira za mankhwalawa zimakhala zapamwamba kwambiri kuposa zoopsa zomwe zingachitike komanso zotsatirapo za rhabdomyolysis.
Mtengo ndi fanizo
Mtengo wa Tricor m'mafakisi amatha kuyambira 500 mpaka 800 rubles, kutengera kulemera (145 kapena 160 mg) magawo, komanso kwa omwe akupanga. Kuphatikiza apo, mtengo wake weniweni ungasiyane kwambiri ndi mitengo yomwe imawonetsedwa pamasamba opangira mankhwala.
Monga fanizo la Tricor, mankhwala monga:
- Zilankhulo
- Lipofem;
- Lipicard
- Lipanorm.
Ndiwotsika mtengo kwambiri kuposa Tricor, ali ndi mndandanda wawo wa zotsutsana, komanso mlingo, womwe umayenera kutsimikiziridwa ndi dokotala. Kugwiritsa ntchito kwawo pawokha sikovomerezeka.
Tricor: ndemanga
Ndemanga pa Tricor ya mankhwala ndi yabwino:
- Yuri, Lipetsk, wazaka 46. Za shuga, sizimachepetsa, ndipo Tricor amalimbana bwino ndi cholesterol. Komabe, kuwongolera ndikofunikira pogwiritsa ntchito biochemistry;
- Elena, Belgorod, wazaka 38. Zinthu zikuyenda bwino. Ndakhala ndikumwa mapiritsi pafupifupi mwezi tsopano, zikuwoneka kuti ndachepa thupi. Posachedwa, pakuumirira kwa adotolo, andiyesa. Ndikuyembekeza nthawi yolandilidwa miyezi itatu;
- Boris, Moscow, wazaka 55. Ndimamwa Tricor wa mankhwala kumapeto kwa miyezi itatu. Kugwiritsa ntchito kwa ine kutsitsa triglycerides.
Makanema okhudzana nawo
Zomwe mukufunikira kudziwa za Tricor mu kanema:
