Chida chimathandizira kuchepa kwa kuthamanga kwa magazi. Zovomerezeka kwa odwala akuluakulu okha. Yogwira gawo la lisinopril imachepetsa mitsempha ya magazi, imachepetsa kuthamanga kwa magazi ndi kuteteza minofu yamtima. Mankhwala amatha kuyeretsa thupi la sodium owonjezera.
Dzinalo Losayenerana
Lisinopril
Chida chimathandizira kuchepa kwa kuthamanga kwa magazi.
ATX
S09AA03
Kutulutsa mafomu ndi kapangidwe kake
Mankhwala amamasulidwa pamapiritsi. Apakikeni zidutswa 20, 30. Lisinopril (lisinopril) ndi chigawo chomwe chimazindikira zotsatira za mankhwala.
Zotsatira za pharmacological
Chosakaniza chophatikizacho ndi ACE inhibitor (chinthu chofunikira kwambiri pakukhazikitsa magazi). Lisinopril amalepheretsa kutembenuka kwa biiology yogwira angiotensin ine oligopeptide kukhala angiotensin ii octapeptide. Pali kuchepa kwa zotumphukira zamitsempha, kutsika kwa mtima, komanso kuchuluka kwamkodzo. Chifukwa chake, chidachi chimachepetsa kuthamanga kwa magazi kukhala milingo yabwinobwino.
Pharmacokinetics
30% odzipereka kuchokera kumimba. Mutha kudya mosasamala za mankhwalawa. Kuchuluka kwazinthu zogwira ntchito m'madzi a m'magazi kumafika pambuyo pa maola 6-7. Nthawi imawonjezeka mpaka maola 8-10 poyerekeza ndi nthawi ya chidziwitso cha pambuyo pakukula. Pafupifupi sizimangiriza mapuloteni amwazi. Hafu ya moyo wa mankhwalawa osasinthika ndi mkodzo ndi maola 12.
Mankhwalawa amachokera 30% pamatumbo.
Zizindikiro zogwiritsidwa ntchito
Wodwala amafunikira chithandizo ngati zotsatirazi zamkati mwa mtima zimachitika:
- patency yowonongeka imodzi kapena zingapo aimpso;
- wodwala anavutika ndi myocardial infarction, koma hemodynamic magawo ndi abwinobwino;
- kuchuluka kwa magazi kwa nthawi yayitali kumadziwika;
- impso zimakhudzidwa ndi odwala omwe amadalira insulin;
- kulephera kwa mtima.
Ndi kuphwanya izi mthupi, adokotala amawona kutalika kwa mankhwalawa komanso kufunika kwa mankhwala ena.
Contraindication
Ndi zoletsedwa kumwa mapiritsi otsatirawa:
- Anachepetsa lumen ya m'mitsempha yamagazi yomwe imadyetsa impso (a impso artery stenosis);
- impso zimayeretsa magazi kuchokera ku creatinine osakwana 30 ml / min;
- anapeza kupweteka kwaimpso;
- pali ziwopsezo zamagulu kapena mankhwala omwe amaphwanya ntchito ya ACE;
- chizolowezi cha angioedema;
- hemodialysis;
- hypertrophic cardiomyopathy, mitral kapena aortic stenosis yokhala ndi vuto la magazi;
- kulephera kwa thupi kupanga lactase;
- pa mkaka wa m'mawere kapena pakati;
- hemodynamic magawo sakhazikika pambuyo pachimake myocardial infarction;
- kuphwanya kutembenuka kwa galactose kukhala glucose;
- shuga-galactose malabsorption syndrome.
Mankhwalawa ali contraindicated mu pachimake aimpso kulephera.
Mphamvu za lisinopril paubwana sizimamveka bwino, chifukwa chake mapiritsi samamwa mpaka zaka 18.
Momwe angatenge
Mankhwalawa amaperekedwa m'mawa. Kuphatikiza apo, muyenera kumwa madzi ambiri. Dokotala azitha kukhazikitsa mtundu wa mankhwalawa atazindikira. Malangizowo akuwonetsa izi:
- Matenda oopsa. Choyamba, imwani 5 mg patsiku. Pambuyo pa masiku 20-30, mutha kuwonjezera kuchuluka kwa tsiku mpaka 10-20 mg. Amaloledwa kutenga 40 mg nthawi imodzi.
- Hypovolemia, matenda amchere amchere, odwala okalamba. Kuchuluka kwa lisinopril ndi 2.5 mg patsiku.
- Pachimake m`mnyewa wamtima infarction ndi khola venous anzawo. 5 mg aledzera masana ndi 5 mg kachiwiri patsiku. Patsiku lachitatu, mlingo umakwera kufika pa 10 mg. Ndi otsika systolic kupanikizika masiku oyamba a 2-3 amapatsa wodwalayo 2.5 mg.
- Matenda ogwirizana. Kuti mukhale ndi khola, tengani 2.5 -5 mg patsiku. Ngati mulingo wochepa kwambiri, ndipo kuthamanga kwa magazi kumapitirira, siyani kumwa mankhwalawa.
- Kulephera kwa mtima. Ndikofunikira kumwa 2.5 mg tsiku lililonse. Pakatha mwezi umodzi, mutha kuwonjezera mlingo mpaka 5 mg.
Pazovuta za mtima, muyenera kumwa 2,5 mg patsiku.
Piritsi lirilonse limakhala ndi magawanidwe ofunika kuwongolera. Ngati ndi kotheka, mutha kugawa piritsi mosavuta. Kutalika kwa kukonza mankhwala sayenera kupitirira 6 milungu.
Ndi matenda ashuga
Ngati motsutsana ndi maziko a matenda ashuga, albuminuria imachitika kapena kuthamanga kwa magazi kukwera, tengani 2 mg. Mlingo wapangidwira mlingo umodzi m'mawa. Ndi ochepetsetsa aimpso ntchito, mankhwalawa akukonzanso akhoza kukhala 5-10 mg patsiku. Zimatengera kuchuluka kwa kuthamanga kwa magazi. Kutalika kwa 20 mg kungatengedwe.
Zotsatira zoyipa
Mankhwalawa amatha kuyambitsa zovuta zomwe zimachokera ku ziwalo ndi machitidwe osiyanasiyana. Nthawi zina, ntchito ya hepatic transaminases imachulukirapo, kuchuluka kwa creatinine ndi urea m'magazi a seramu kumawonjezeka.
Matumbo
Nthawi zambiri odwala amasokonezedwa ndi chopondapo, mseru. Kupweteka kumachitika m'mimba, nseru. Kugwiritsa ntchito nthawi yayitali kungayambitse kutupa kwa kapamba, kulephera kwa chiwindi, kuchuluka kwa bilirubin m'magazi.
Mukamamwa mankhwalawa, mseru ungachitike.
Hematopoietic ziwalo
Mothandizidwa ndi lisinopril, kuthamanga kwa magazi kumachepa. Nthawi zina, kugunda kwamtima kwamphamvu kumamveka, tachycardia imachitika, ndipo mitsempha ndi ma arterioles am'mphepete amakhudzidwa (matenda a Raynaud). Yogwira pophika mankhwala ingayambitse kuphwanya kwa magazi kupita ku minofu ya mtima ndi matenda a mtima, ngati kulandilidwa sikukonzedwa.
Pakati mantha dongosolo
Nthawi zambiri mutatha chizungulire, kupweteka kwa mutu kumawonekera, kutopa kumawonjezeka, ndipo chidwi chachikulu chimachepa. Kusokonezeka kwa malingaliro, paresthesia, kugona, kapena kugona.
Kukhumudwa, kukomoka, ndi chisokonezo zimachitika pambuyo pogwiritsa ntchito nthawi yayitali komanso mosalamulirika.
Kuchokera ku kupuma
Pambuyo pa makonzedwe, zizindikiro zimatha kuchitika zomwe zimafanana ndi chimfine: chifuwa chowuma, zilonda zapakhosi ndi kuwuma, mphuno ya mphuno ndi paranasal sinuses. Nthawi zambiri, bronchospasm imachitika.
Mukatha kumwa, mutha kupeza zizindikiro zofanana ndi chimfine: chifuwa chowuma, zilonda zapakhosi.
Pa khungu
Allergies amatha kuoneka ngati kutupa kwa nkhope ndi mbali zina za thupi, urticaria. Odwala ena amakhala ndi matenda a Stevens-Jones, mphamvu ya thupi kumaonera kuwala kwa ultraviolet imawonjezeka, kupweteka kwa minofu kumamveka.
Kuchokera ku genitourinary system
Ntchito yeniyeni nthawi zambiri imasokonekera ndi lisinopril. Nthawi zina, mumakhala uremia, proteinuria, kusowa kwa mkodzo.
Malangizo apadera
Pa chithandizo, ndikofunikira kuwongolera kuthamanga kwa magazi. Asanatenge, ma diuretics amachotsedwa kuti muchepetse chiopsezo chochepetsera kupanikizika. Chithandizo cha lisinopril sichiyenera kuyamba ngati, ndi kupweteka kwambiri kwa myocardial infarction, kuwonedwa. Kulowerera kolowera kulephera kwa mtima nkoletsedwa, chifukwa zizindikiro zimatha kuonekanso patapita kanthawi.
Gwiritsani ntchito mu ukalamba
Mukakalamba, zotsatira za lisinopril zitha kutchulidwa kwambiri. Chithandizo chikuyenera kuchitika mosamala.
Mukakalamba, zotsatira za lisinopril zitha kutchulidwa kwambiri.
Zokhudza mphamvu pakuwongolera njira
Chifukwa cha kutopa kwambiri, mawonekedwe a chizungulire komanso kupweteka kwa mutu mwa odwala ena, ndikofunikira kuwongolera magalimoto mosamala.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Pa nthawi yoyembekezera, kugwiritsa ntchito mankhwalawa ndizoletsedwa. Lisinopril angayambitse kusokoneza kwa fetal, komwe mwina sikungagwirizane ndi moyo. Palibe umboni woti kulowerera mkaka wa m'mawere, koma tikulimbikitsidwa kusiya kuyamwitsa pamene mukumwa mankhwalawa.
Kulembera Lisinopril Stad kwa ana
Mpaka wazaka 18, mankhwalawa sanalembedwe, chifukwa chitetezo ndi kuchita bwino muubwana sizimamveka bwino.
Mpaka wazaka 18, mankhwalawa sanalembedwe, chifukwa chitetezo ndi kuchita bwino muubwana sizimamveka bwino.
Bongo
Kumwa mapiritsi osalamulirika kumabweretsa mawonekedwe a ochepa hypotension, mantha, bradycardia, ndi kulephera kwa aimpso. Wodwalayo amasokonezeka ndi malire a electrolyte.
Kuchita ndi mankhwala ena
Ntchito munthawi yomweyo mankhwala ena amayambitsa zotsatirazi:
- okodzetsa ndi mankhwala ena omwe amachititsa kutsika kwa magazi kuthamanga kungalimbikitse zotsatira za mankhwalawa;
- potaziyamu kuteteza okodzetsa kungayambitse hyperkalemia;
- mothandizidwa ndi ma pinkiller ndi mankhwala omwe si a antiidalidal anti-yotupa, zotsatira za hypotensive sizimachitika mwachangu;
- ngati mchere wa lithiamu umagwiritsidwa ntchito, ndikofunikira kuyang'anira kuchuluka kwa mankhwala m'magazi;
- kuchuluka kwa mankhwalawa kwa lisinopril kumalimbikitsidwa pakumwa mapiritsi ogonetsa ndi mankhwala oletsa kupweteka;
- othandizira omwe amawonjezera kutulutsa kwa norepinephrine amatha kufooketsa mphamvu ya lisinopril;
- munthawi yomweyo makonzedwe ndi Allopuronol, Procainamide, cytostatics, immunosuppressants, systemic glucocorticoids amatsogolera kuchepa kwa maselo oyera amwazi m'magazi;
- mphamvu ya kumwa mankhwala antidiabetes imafooka;
- sodium chloride imatha kuchepetsa zotsatira za antihypertensive mankhwala.
Kuyenderana ndi mowa
Mowa umawonjezera mphamvu ya mankhwalawa, kotero kumwa zakumwa sizikulimbikitsidwa.
Mowa umawonjezera mphamvu ya mankhwalawa, kotero kumwa zakumwa sizikulimbikitsidwa.
Ndi chisamaliro
Chenjezo liyenera kuchitidwa kupweteka pachifuwa komwe kumayamba chifukwa cha kusakwanira kwa magazi ku minofu ya mtima. Ndikofunikira kufunsa dokotala ndi kuwonongeka kwa ziwiya zaubongo, kuti musayambitse stroke. Ngati vuto la aimpso lofooka, mulingo wake umakhala wochepa.
Analogi
Mankhwalawa ali ndi ma analogu omwe amatha kusintha chida ichi. Izi zikuphatikiza:
- Lisinopril. Mtengo wake saposa ma ruble 80 pamapiritsi 30. Kuchuluka kwa zinthu zomwe zikugwiritsidwa ndi mapiritsi zimatha kukhala zosiyana.
- Lisinotone. Zimapezeka mzidutswa 28 pakompyuta. Mtengo wake ndi ma ruble a 120-200. Muli sodium. Ndi masanzi ndi kutsekula m'mimba ziyenera kugwiritsidwa ntchito mosamala. Mu ukalamba ndizoletsedwa kutenga.
- Lysigamm. Mtengo wa zidutswa 30 ndi ma ruble 130. Monga gawo la osinopril ndi othandizira pazinthu. Ndikulimbikitsidwa kuti musamale mosamala pazinthu zina kapena matenda.
- Diroton. Amatulutsa zidutswa 14, 56 pa paketi iliyonse. Mtengo wa mankhwalawa umasiyanasiyana kuchokera ku 200 mpaka 700 rubles. Zofanana ndi Lisinopril Stad. Amagwiritsidwanso ntchito kuti azisungunuka magawo a hemodynamic mu infarction ya myocardial.
Musanagule mankhwala ndi analogue, funsani katswiri. Malangizo akuwonetsa zoyipa zoyipa ndi zotsutsana.
Kupita kwina mankhwala
Muyenera kupereka mankhwala kuchipatala kuti mugule mankhwalawo.
Kodi ndingagule popanda kulandira mankhwala?
Tchuthi chotsutsana ndi chipinda chamankhwala ndizotheka.
Mtengo wa Lisinopril Stada
Mtengo wamapiritsi ku Russia ndi wochokera ku ruble 100 mpaka 170.
Zosungidwa zamankhwala
Sungani phukusi la piritsi pamalo amdima mpaka kutentha + mpaka 25 ° C.
Sungani phukusi la piritsi pamalo amdima mpaka kutentha + mpaka 25 ° C.
Tsiku lotha ntchito
Mutha kusunga zaka 3.
Wopanga
MAKIZ-PHARMA LLC kapena Hemofarm LLC, Russia.
Ndemanga za Lisinopril Stad
Mankhwalawa ndiokwera mtengo, koma pali zingapo zoyipa ndimomwe zimachitikira. Ambiri amakana kulandira chifukwa mankhwalawo samayamba nthawi yomweyo.
Pa nthawi yoyembekezera, kugwiritsa ntchito mankhwalawa ndizoletsedwa.
Madokotala
Egor Konstantinovich, katswiri wamtima
Ndimapereka mankhwala a Lisinopril Stad ndi mankhwala ena kuti ndikwaniritse bwino. Kuphatikiza apo, wodwalayo ayenera kukhazikitsa zakudya. Mankhwala osokoneza bongo, mankhwalawa amatsogolera pakupuma kwamitsempha ya mtima komanso kuchepa kwa kuthamanga kwa magazi.
Julia Makarova, wamisala
Ndi kuchuluka kwa nthawi yayitali kukakamizidwa, mankhwalawa amathandiza. Mankhwalawa amayamba kuchita pakadutsa mphindi 40-60. Ndikofunika kutenga pafupifupi mwezi umodzi, kutsatira upangiri wa adokotala. Potenga chithandizo, ndikofunikira kuwunika momwe impso zimayendera. Kumbukirani kuti sikofunikira kuphatikiza kutenga mapiritsi ndi hemodialysis kudzera mumagwira bwino kwambiri.
Odwala
Sergey Viktorovich, wazaka 45
Anamuthandizanso mankhwalawa ndipo patatha masiku 10 anali kumva bwino. Kupanikizika kumawuka, koma kawirikawiri. Mutu unasiya kuvutika. M'masiku oyamba kukamwa, mucous nembanemba mkamwa anali wouma ndipo amamva kupweteka. Zotsatira zake zidasowa patatha sabata limodzi. Kukhutitsidwa ndi zotsatira za kumwa mankhwalawo.
Egor, wazaka 29
Pambuyo pa kudya kwa nthawi yayitali, kudwala chifuwa komanso zilonda. Dotolo yemwe adakhalapo adathetsa izi ndipo adalangiza kuti atenge mankhwala ena. Chenjezo liyenera kuchitika pakapita nthawi yayitali.
Anastasia Romanovna, wa zaka 32
Mankhwalawa anathandizira kuchepa kwa magazi pamagazi. Njira yothandiza yomwe agogo anga adalandira atadwala sitiroko. Wopanga wabwino komanso mtengo wololera.
