Lizoril mankhwala: malangizo ntchito

Lysoril, kapena lisinopril dihydrate, ndi mankhwala apiritsi omwe amagwiritsidwa ntchito kutsitsa kuthamanga kwa magazi akakwera (matenda oopsa).

Dzinalo Losayenerana

Lisinopril.

Lysoril, kapena lisinopril dihydrate, ndi mankhwala omwe amagwiritsidwa ntchito kutsitsa magazi akakwera.

ATX

Mankhwalawa ali ndi C09AA03 Lisinopril.

Kutulutsa mafomu ndi kapangidwe kake

Amapezeka m'mitundu monga mapiritsi okhala ndi 2.5; 5; 10 kapena 20 mg aliyense.

Monga gawo la mankhwalawa, chinthu chachikulu chomwe chimagwira ndi lisinopril dihydrate. Zina zowonjezera ndi mannitol, calcium hydrogen phosphate dihydrate, magnesium stearate, wowuma chimanga, E172, kapena iron ironide.

Mapiritsiwo ndi ozungulira, a biconvex, apinki okongola.

Zotsatira za pharmacological

Amatanthauzanso mankhwala omwe amakhudza mtima wamtima. Mankhwala amalepheretsa kusintha kwa angiotensin 1 mpaka angiotensin 2, wokhala ndi vasoconstrictor zotsatira ndipo amaletsa mapangidwe a adrenal aldosterone. Amachepetsa zotumphukira zamitsempha, kuthamanga kwa magazi, kupanikizika kwa ma capillaries am'mapapo, preload. Zimakonza kutulutsa kwamtima ndi mtima ndipo zimathandizira kulolerana kwamtima mwa anthu omwe ali ndi vuto la mtima.

Kutsitsa magazi kumachitika ola limodzi mutatha kumwa mankhwalawo.

Pogwiritsa ntchito Lizoril kwa nthawi yayitali, kuchepa kwa myocardial hypertrophy ndi makoma ochepa a mtundu wotsalira. Kutsitsa magazi kumachitika ola limodzi mutatha kumwa mankhwalawo. Kupambana kwakukulu kumatheka pambuyo pa maola 6, kutalika kwa zotsatira kumakhala pafupifupi tsiku. Zimatengera mlingo wa chinthu, momwe thupi limagwirira ntchito, impso ndi chiwindi.

Pharmacokinetics

Kwambiri ndende amawona maola 7 pambuyo makonzedwe. Wapakati womwe umalowa m'thupi ndi 25%, wocheperako ndi 6%, ndipo wokwera ndi 60%. Odwala omwe ali ndi vuto la mtima, bioavailability amachepetsedwa ndi 15-20%.

Adatulutsidwa mkodzo wosasinthika. Kudya sizimakhudza mayamwidwe. Kuchuluka kwa malowedwe kudzera mu chotchinga ndi magazi-chotchinga cha magazi ndi kotsika.

Zizindikiro zogwiritsidwa ntchito

Mankhwalawa amalembedwa motere:

• yochepa mankhwala a pachimake myocardial infarction (mpaka milungu 6);
• matenda oopsa;
• matenda ashuga nephropathy (kuchepetsa mapuloteni mu mkodzo mwa odwala matenda ashuga omwe ali ndi magazi abwinobwino komanso okwera).

Contraindication

Sizoletsedwa kutenga ngati atchulidwa:

1. Hypersensitivity ku gawo lililonse la mankhwala kapena mankhwala ochokera ku gulu limodzi la pharmacological.
2. Edema m'mbiri ya mtundu wa angioneurotic.
3. Osakhazikika hemodynamics pambuyo pachimake myocardial infaration.
4. Kukhalapo kwa milingo yayikulu ya creatinine (yoposa 220 μmol / l).

Mankhwalawa amadziwikiritsa kwa odwala omwe akudwala hemodialysis, komanso azimayi omwe ali ndi pakati ndi kumwitsa.

Mankhwalawa amalembedwa kwa odwala omwe akudwala hemodialysis.

Mankhwalawa amakwiriridwa kwa amayi panthawi yapakati.

Mankhwalawa amaperekedwa kwa azimayi omwe akuyamwitsa.

Ndi chisamaliro

Mankhwalawa amatchulidwa mosamala pamaso pa arstial stenosis kapena ma valve - mitral ndi aortic, matenda a impso ndi chiwindi, vuto la mtima, kukhathamiritsa potaziyamu, pambuyo pochita opaleshoni komanso kuvulala, ndi matenda a shuga, matenda a m'magazi, matupi awo sagwirizana.

Momwe mungatenge Lizoril?

Mu nthawi 1 patsiku. Mlingo wa mankhwalawa amasankhidwa mosiyanasiyana. Nthawi zambiri, chithandizo chimayamba ndi 10 mg. Kenako sinthani ngati pakufunika kutero.

Ndi matenda ashuga

Odwala omwe ali ndi matenda a shuga a 2, muyeso woyamba wa mankhwalawa ndi 10 mg 1 nthawi patsiku.

Zotsatira zoyipa za Lizoril

Mankhwala amatha kuyambitsa mavuto, ena amachoka okha, ena amafuna chithandizo.

Matumbo

Pakamwa pakamwa ndi mseru, kusanza, kupweteka kwam'mimba, kutsegula m'mimba, kudzimbidwa, kutupa kwa kapamba, kuchepa kwa chakudya, kufooka kwa chiwindi, jaundice, cholestasis, angioedema wamatumbo, hepatocellular mtundu wa hepatitis.

Kuchokera m'matumbo am'mimba, zotsatira zoyipa zimatha kupezeka mwa kusanza.

Kuchokera m'matumbo, zovuta zoyambira m'mimba zimatha kuchitika.

Kuchokera m'matumbo, zoyipa zamkati mwa kufooka kwa chiwindi zimatha kuchitika.

Kuchokera pamimba, m'mimba zimayambitsa kupweteka kwa kapamba.

Hematopoietic ziwalo

Kuchepetsa hematocrit ndi hemoglobin, chopinga cha kufupika kwa mafupa, kusintha kwamitsempha yamagazi, thrombocytopenia, agranulocytosis, neutropenia, leukopenia, matenda a autoimmune, lymphadenopathy, hemolytic.

Pakati mantha dongosolo

Vuto la kusokonezeka kwa thupi, kukomoka, kupindika kwa minofu, kumva kununkhira, kuchepa kwa chidwi, kutsekemera, kusamva bwino ndi kukoma, mavuto ogona, kusinthasintha kwa mutu, kupweteka kwa mutu komanso chizungulire.

Kuchokera ku kupuma

Kupepuka kupuma thirakiti matenda, chifuwa, kupindika, kupuma komanso kuphipha, kufupika, kutulutsa zamkono zamkati, chifuwa.

Kuchokera pamtima

Orthostatic phenomena (ochepa hypotension), stroko, myocardial infarction, matenda a Raynaud, palpitations, Cardiogenic mantha, mtima block 1-3 madigiri, kukhathamira kwa mapapu.

Matupi omaliza

Zotheka khungu ndi subcutaneous wosanjikiza monga totupa, kuyabwa, kuchuluka mphamvu - angioedema, kutupa kwa zimakhala ndi nkhope ndi khosi, hyperemia, urticaria, eosinophilia.

Zotheka kusintha pakhungu ndi subcutaneous wosanjikiza, monga totupa, kuyabwa.

Zokhudza mphamvu pakuwongolera njira

Chifukwa mukamamwa Lizoril, pakhoza kukhala chizungulire, kusowa kolowera, ndiye mukamagwira ntchito ndi njira zovuta komanso magalimoto oyendetsa galimoto, kusamala kwakukulu kuyenera kuchitika kapena mtundu uwu wa ntchito uyenera kusiyidwa ngati kuli kotheka.

Malangizo apadera

Mlingo wa mankhwalawa ungasiyane, kutengera zaka, magwiridwe antchito a ziwalo (mtima, chiwindi, impso, mtsempha wamagazi).

Ndi matenda a mtima, matenda a mtima. Chifukwa chake, kusintha kwa mankhwalawa ndikuwonetsetsa momwe odwala alili pamafunika.

Gwiritsani ntchito mu ukalamba

Kusintha kwa magazi kuyenera.

Kupatsa ana

Mankhwala contraindised ana, chifukwa palibe maphunziro azachipatala omwe adachitidwapo.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Osasankha.

The ntchito aimpso kuwonongeka

Popereka mankhwala kwa odwala omwe amalephera kupweteka kwa aimpso, muyezo wake umatsimikiziridwa ndi mulingo wa creatinine m'magazi ndi momwe thupi limayankhira chithandizo.

Popereka mankhwala kwa odwala omwe amalephera kupweteka kwa aimpso, muyezo wake umatsimikiziridwa ndi mulingo wa creatinine m'magazi ndi momwe thupi limayankhira chithandizo.

Ndi a mafupa a minyewa ya m'magazi, mankhwala amatha kuyambitsa magazi mu urea ndi milingo ya creatinine, matenda oopsa a impso, kapena matenda oopsa kwambiri. Ndi anamnesis otere, ndikofunikira kupereka mosamala kuchuluka kwa okodzetsa ndikuwunika bwino mlingo, kuwongolera mulingo wa potaziyamu, creatinine ndi urea.

Ndi chitukuko cha myocardial infarction mwa odwala mkhutu aimpso, Lizoril ndi contraindicated.

Gwiritsani ntchito ntchito yolakwika ya chiwindi

Kugwiritsa ntchito mankhwala sikamayambitsa matenda a hepatobiliary system. Komabe, nthawi zina okhala ndi chiwindi chokhazikika, jaundice, hyperbilirubinemia / hyperbilibinemia, komanso kuwonjezeka kwa hepatic transaminase ntchito kumatha. Pankhaniyi, mankhwalawa adathetsedwa.

Mankhwala ochulukirapo a lizoril

Zizindikiro zimawonekera mu mawonekedwe a kuchepa kwa kuthamanga kwa magazi, kusasamala mu ma elekitirodi, kulephera kwa impso, tachy kapena bradycardia, chizungulire, chifuwa, nkhawa. Chithandizo cha Syndrome chimachitika.

Chizungulire ndi chimodzi mwazizindikiro za bongo.

Ndikofunika kutsuka m'mimba, kutsuka, kupereka mafinya kapena kufinya. Woopsa milandu, kulowetsedwa mankhwala zotchulidwa, catecholamines kutumikiridwa m`nsinga.

Kuchita ndi mankhwala ena

Ma diuretics: pali kuwonjezeka kwa zotsatira za kutsitsa magazi.

Lithium: Kugwiritsa ntchito mosavomerezeka sikulimbikitsidwa. Kuopsa kumawonjezeka. Ngati ndi kotheka, onetsetsani mulingo wa lithiamu m'magazi.

NSAIDs: zotsatira za zoletsa za ACE zimachepa, pali kuwonjezereka kwa potaziyamu m'magazi, zomwe zimawonjezera chiopsezo cha kuwonongeka kwa impso.

Mankhwala osokoneza bongo a shuga: kuchepa kwamphamvu kwa shuga m'magazi, chiopsezo cha hypoglycemia ndi chikomokere zimachuluka.

Estrogens: kusunga madzi mthupi, motero amatha kuchepetsa mphamvu ya mankhwalawo.

Mankhwala ena ochepetsa kuthamanga kwa magazi ndi ma antidepressants: chiwopsezo cha kuchepa kwambiri kwa magazi.

Kuyenderana ndi mowa

Ndikusowa. Mwina kuwonjezeka kwa hypotensive zotsatira za lisinopril, ochepa hypotension angayambe.

Analogi

Zofananira za Lizoril ndi Lisinoton, Lisinopril-Teva, Iramed, Lisinopril, Diroton.

Kupita kwina mankhwala

Kuperekera kwa mankhwala kuchipatala ndikofunikira.

Kodi ndingagule popanda kulandira mankhwala?

Ayi.

Mtengo

Mtengo wa phukusi limodzi ndiwosiyana kutengera kuchuluka kwa mapiritsi ndi kipimo. Chifukwa chake, mtengo wa mapiritsi 28 a 5 mg a chinthucho ndi ma ruble 106.

Zosungidwa zamankhwala

Ndikulimbikitsidwa kusunga malonda m'malo omwe ana sangathe. Ulamuliro wa kutentha suyenera kupitirira 25 ° C.

Tsiku lotha ntchito

Osapitilira zaka zitatu.

Wopanga

Kampani ya India Ipka Limited Laboratories.

Mankhwala contraindised ana, chifukwa palibe maphunziro azachipatala omwe adachitidwapo.

Ndemanga

Oksana, wazaka 53, Minsk: "Lizoril adayikidwa zaka 3 zapitazo chifukwa cha kuthamanga kwa magazi. Madontho munthawi imeneyi adayamba kukhala ocheperako. Ngakhale mulingo wothinana ukakweza, siwokwera kwambiri (asanafike 180). Ndidasiya kuwopa kuwopsa. palibe chowonekera. "

Maxim, wazaka 28, Krymsk: "Ndakhala ndikudwala matenda oopsa kuyambira ndili mwana. Ndinayesa mankhwala ambiri panthawiyi, koma kupanikizika kumachitika kawirikawiri. Zaka ziwiri zapitazo, adotolo adapanga maphunziro a Lizoril. Zizindikiro tsopano sizikuvutitsa, koposa zonse, palibe kugwa kwakukulu. kupanikizika, ndipo izi zisanachitike ndimakhala wosazindikira chifukwa cha izi. Matenda oopsa amathodwa. Ndakhuta. "

Anna, wazaka 58, St. Petersburg: "Ndakhala ndikugwiritsa ntchito mankhwalawa kwa miyezi isanu ndi umodzi (ndikuwongolera kwa creatinine). Matenda oponderezedwa abwerera mwakale. Vuto limakhalapo chifukwa ndimakhala ndi nephropathy poyerekeza ndi maziko a matenda a shuga a 2, kotero ndimakonda kuyesedwa ndipo nthawi zina adotolo Amasintha mankhwalawa. Koma ndimakonda mankhwalawa chifukwa palibe zotsatira zoyipa ndipo ndiwothandiza kumwa kamodzi patsiku. "