Mankhwala Mepharmil: malangizo ntchito

Mepharmil amadziwika ndi zotsatira za hypoglycemic. Amagwiritsidwa ntchito pochiza matenda a shuga mellitus wachiwiri. Ngati mutsatira zakudya, zimapangitsa mwachangu komanso mosatha kupanga shuga.

Dzinalo Losayenerana

Metformin.

ATX

Khodi ya ATX: A10V A02.

Mepharmil amagwiritsidwa ntchito pochiza matenda a shuga a mtundu wachiwiri.

Kutulutsa mafomu ndi kapangidwe kake

Amapezeka m'mapiritsi omwe amakhala ovomerezeka. Chofunikira chachikulu ndi metformin hydrochloride, mlingo wa 500, 850 kapena 1000 mg piritsi limodzi. Zowonjezera:

1. 500 ndi 850 mg mapiritsi: sodium wowuma glycolate, chimanga wowuma, povidone, magnesium stearate, silicon dioxide. Ulusi wa kanema umakhala ndi hypromellose, polyethylene glycol, talc, propylene glycol ndi titanium dioxide. Mapiritsiwo ndi ozungulira, oyera kapena zonona, opakidwa mozungulira m'mbali.
2. Mapiritsi 1000 mg: magnesium stearate, povidone. Utoto wa kanema umapangidwa ndi hypromellose, polyethylene glycol 6000 ndi 400. Mapiritsi okhala ndi kapisozi ndi zoyera kapena zonona mu utoto, wokhala ndi mzere mbali zonse.

Zotsatira za pharmacological

Amatanthauzanso ma biguanides okhala ndi antihyperglycemic. Glucose amatsitsidwa pamimba yopanda kanthu ndikatha kudya. Katemera wa insulini samachuluka, kutchulidwa kwa hypoglycemic sikumawonedwa.

Kuletsa kwa gluconeogenesis njira kumachitika, pomwe shuga secretion mu chiwindi amachepetsa. Kuzindikira kwamapangidwe amtundu wa minofu kuti insulin iwonjezeke, kugwiritsidwa ntchito kwa glucose mu zotumphukira zimakhala bwino. Kuyamwa kwa shuga m'matumbo kumachepera.

Chithandizo chogwira mtima chimapangitsa kapangidwe ka glycogen mkati mwa maselo. Metformin imasintha kagayidwe ka lipid. Zomwe zili triglycerides ndi cholesterol zimachepa. Pogwiritsa ntchito odwala nthawi yayitali, thupi limachepa pang'onopang'ono.

Mankhwalawa amapezeka pamapiritsi, omwe amaphatikizidwa ndi zokutira filimu.

Pharmacokinetics

Kuzindikira kwakukulu kumawonedwa patatha maola awiri mutamwa mapiritsi. Metformin imadziunjikira m'chiwindi, tiziwopsezo toterera, impso, ndi minofu. The bioavailability ndi kuthekera kumangiriza kupangira mapuloteni ndizosatheka. Chidacho chopopera chimapukusidwa pafupifupi maola 6 ndi mkodzo, osasinthika. Ma metabolabol sapanga.

Zizindikiro zogwiritsidwa ntchito

Zowonetsa mwachindunji pakugwiritsa ntchito mankhwalawa ndi:

• lembani matenda ashuga a shuga 2 (omwe samatha kudya komanso kuchita masewera olimbitsa thupi);
• mankhwala a mono-kapena zovuta ndi insulin pochizira akuluakulu, ana kuyambira zaka 10 ndi achinyamata;
• kumasuka kwamavuto amtundu wa 2 wa shuga mwa anthu onenepa kwambiri.

Nthawi zambiri mankhwalawa amagwiritsidwa ntchito pakuchepetsa thupi. Koma ndikulimbikitsidwa kuti muzitenga mosamalitsa malinga ndi momwe zikuwonetsedwera komanso mulingo wofotokozedwa bwino.

Contraindication

Sizoletsedwa kupereka mankhwala a:

• Hypersensitivity ku zigawo zikuluzikulu;
• matenda ashuga ketoacidosis;
• precom
• matenda aimpso;
• kusowa kwamadzi;
• matenda opatsirana opatsirana;
• mtima wosakhazikika;
• kupuma movutikira;
• infarction waposachedwa waposachedwa;
• kulephera kwa chiwindi;
• poyizoni woledzera.

Mankhwala ndi contraindicated kwambiri matenda opatsirana.

Mankhwala ali contraindised mu mtima kulephera.

Mankhwala contraindicated mu myocardial infarction.

Mankhwalawa amadziwikiridwa ndi zakumwa zoledzeretsa.

Momwe mungatenge mefarmil?

Mlingo woyambirira wa akuluakulu ndi 500 kapena 850 mg kawiri tsiku lililonse mutatha kudya. Popereka mankhwala okwanira, mapiritsi awiri a 500 mg amatha kuthandizidwa ndi 1000 mg. Mlingo wambiri watsiku ndi tsiku sayenera kupitirira 3000 mg, womwe umagawidwa pazigawo zitatu.

Ndi matenda ashuga

Mlingo wa tsiku ndi tsiku si oposa 1000 mg. Ngati ndi kotheka, imatha kuwonjezeredwa ku 2000 mg patsiku, yogawidwa pawiri. Nthawi zina, mlingo umatha kuchepetsedwa kapena kuchuluka (izi zimachitika chifukwa cha kusinthasintha kwa glucose m'magazi).

Zotsatira zoyipa za Mepharmila

Kumayambiriro kwa mankhwalawa, kupatsirana kumatha kuchitika mwanjira ya mseru, kusanza, kutsegula m'mimba, kusowa chilimbikitso, komanso kupweteka kwam'mimba. Nthawi zambiri, zizindikirozi zimangokhala zokha ndipo sizifuna chithandizo chilichonse.

Kuphatikiza apo, mankhwalawa amayambitsa zovuta izi:

• kagayidwe kachakudya matenda;
• kuphwanya kukoma;
• lactic acidosis;
• kuchepa mayamwidwe ndi kuchuluka kwa vitamini B12 m'magazi;
• yotupa chiwindi;
• chiwindi ntchito;
• zotupa pakhungu limodzi ndi kuyabwa;
• urticaria.

Urticaria ndi chimodzi mwanjira zoyipa za kumwa mankhwalawa.

Zambiri mwa izi zimachitika pazokha, koma nthawi zina zimakhala zofunikira kusintha mankhwalawo kapena kusiya mankhwala onse.

Zokhudza mphamvu pakuwongolera njira

Monotherapy yokhala ndi metformin siyimapangitsa kukula kwa hypoglycemia, motero, ndipo sikutanthauza kuchepa kwa ndende. Magalimoto amatha kuyendetsedwa ndi mankhwalawa, ndipo kuchuluka kwakeko sikuchepetsa.

Chenjezo liyenera kuchitika mukamamwa mankhwalawa ndi mankhwala ena a hypoglycemic m'njira yovuta chifukwa chotheka kukhala ndi hypoglycemia, yomwe imakhudza ndende.

Malangizo apadera

Zotsatira za kuchuluka kwa metformin, lactic acidosis imachitika. Imadziwoneka yokha mwa kupweteka kwakukulu, mavuto a dyspeptic, asthenia. Chenjezo liyenera kuonedwa kwa anthu omwe ali ndi vuto la impso ndi kwa chiwindi. Kusintha kulikonse kwaumoyo wathanzi, kusintha kwamankhwala kwa mankhwala kumafunika. Nthawi zambiri megaloblastic anemia ndi lactic acidosis imayamba.

Chenjezo liyenera kuchitika mukamagwiritsa ntchito mankhwalawa kwa anthu okalamba.

Kugwiritsira ntchito pamodzi kwa maphikidwe a vegan ndi mankhwala achikhalidwe omwe ali ndi metformin ndikotheka, koma kokha ndikuyang'aniridwa ndi achipatala. Maphikidwe enanso amangothandiza kuti mankhwalawo akhale abwino, koma sizingakhale maziko ake.

Gwiritsani ntchito mu ukalamba

Chenjezo liyenera kugwiritsidwa ntchito ngati mugwiritsa ntchito mankhwalawa mu okalamba, chifukwa atha kukhala ndi hypoglycemia. Ndikofunikira kuyang'anira kusintha kulikonse pazotsatira zoyesa kuti musinthe mankhwalawa panthawi.

Kupatsa ana

Ngakhale palibe umboni kuti chinthucho chikugwiririka mwanjira iliyonse chimakhudza kutha, sibwino kupereka mankhwala kwa ana. Chithandizo chotere chimagwiritsidwa ntchito pokhapokha atatsimikizira kuti ali ndi matenda a shuga a 2.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Chiwopsezo chachikulu kwa mwana wosabadwayo chimapezeka mwa amayi apakati omwe ali ndi matenda ashuga, chifukwa chifukwa cha ichi, ena obadwa mwatsopano amayamba. Komabe, kudya kwa mapiritsi a Mefarmil sikukukhudza kukula kwawo. Chithandizo pa gestation n`chotheka pokhapokha kuyangʻaniridwa ndi dokotala mosamala kuyang'anira shuga.

Kutenga mapiritsi a Mefarmil sikukhudza mwana wam'tsogolo.

Ngakhale mankhwalawa samakhudza mwana movutikira, amalowa mkaka wa m'mawere ochuluka, chifukwa chake ndibwino kukana kuyamwitsa nthawi yayitali ndi mankhwalawa.

The ntchito aimpso kuwonongeka

Ndi matenda a impso, kusinthasintha kwa Mlingo wofunikira kumafunika kukumbukira kusinthasintha kwa shuga m'magazi.

Gwiritsani ntchito ntchito yolakwika ya chiwindi

Ngati chiwindi sichitha, kusintha kwa mankhwalawa kumafunika. Ndi kuwonongeka kwakanthawi pazotsatira zoyesa kwa chiwindi, mlingo woyenera wofunikira umayikidwa. Ngati siyikupereka chithandizo chokwanira, ndibwino kukana chithandizo chotere.

Mankhwala ochulukirapo a Mefarmil

Ndi kumwa kamodzi pamankhwala oposa 850 mg, zizindikiro za hypoglycemia sizinawoneke. Mwina kukula kwa lactic acidosis. Izi ndi zochitika zadzidzidzi zomwe zimangofunika chithandizo chamankhwala. Ndikotheka kuchotsa metformin ndi lactate kuchokera mthupi kudzera hemodialysis.

Ndikotheka kuchotsa metformin ndi lactate kuchokera mthupi kudzera hemodialysis.

Kuchita ndi mankhwala ena

Kugwiritsa ntchito palimodzi ndi ayodini komwe kumakhala mankhwala kumabweretsa kuoneka ngati kulephera kwa impso. Othandizira pamagalimoto a X-ray amasokoneza kukula kwa lactic acidosis.

Mosamala, tikulimbikitsidwa kumwa mapiritsi limodzi ndi antihyperglycemic othandizira ndi sympathomimetics, komanso nicotinic acid. Pankhaniyi, muyenera kuyang'anira kuchuluka kwa shuga m'magazi, kusintha mlingo womwe umaganizira kusintha kwazomwe mukukhala ndi thanzi limodzi.

Ma diuretics amathandizira kukulitsa lactic acidosis ndipo amatsogolera kuchepa kwamphamvu kwa impso.

Kuyenderana ndi mowa

Kulumikizana ndi mafuta acids, ethanol imayambitsa kukula kwa lactic acidosis ndipo imabweretsa kukula kwa chiwindi cholephera. Chifukwa chake, mankhwalawa sagwirizana ndi mowa.

Mankhwalawa sagwirizana ndi mowa.

Analogi

Pali zithunzi zambiri zomwe zimafanana ndi zomwe zikuchitika komanso zomwe zaperekedwa. Izi zikuphatikiza:

• Bagomet;
• Glycometer;
• Glucovin Xr;
• Glucophage;
• Glumet;
• Dianormet;
• Diaformin;
• Insufor;
• Langerin;
• Meglifort;
• Methamine;
• Metfogamm;
• Metformin Hexal;
• Metformin Zentiva;
• Metformin Astrapharm;
• Metformin Teva;
• Metformin Sandoz;
• Metformin MS;
• Panfort;
• Siofor;
• Zukronorm.

Kupita kwina mankhwala

Imapezeka pokhapokha ngati mwalandira chithandizo chamankhwala.

Kodi ndingagule popanda kulandira mankhwala?

Zosatheka.

Mtengo wa Mepharmil

Mtengo wake umachokera ku ma ruble 120 mpaka 280. kunyamula.

Zosungidwa zamankhwala

Sungani kokha phukusi loyambirira, m'malo amdima komanso owuma kumene ana sangathe kufikira, kutentha kusapitirire + 25 ° C.

Tsiku lotha ntchito

Zaka 3 kuyambira tsiku lopangira lomwe lasonyezedwa pazomwe zidapangidwira koyambirira. Osagwiritsa ntchito kumapeto kwa nthawi ino.

Alumali moyo wa mankhwalawa ndi zaka 3 kuyambira tsiku lopangira lomwe lasonyezedwa poyambitsidwa koyambirira.

Wopanga

PJSC "Kievmedpreparat", Kiev, Ukraine. Ku Russia, chida ichi sichipangidwa.

Ndemanga za Mepharmil

Lyudmila, wazaka 45, Arkhangelsk

Kwa nthawi yayitali ndakhala ndikuvutika ndi matenda ashuga a 2. Ndayesapo kale mankhwala ambiri, koma sanathe. Dokotala adalangiza kuti atenge mapiritsi a Mefarmil. Zotsatira zake za mankhwalawa zidakhutira. Kumwa mankhwalawa sikubweretsa zovuta zilizonse, chifukwa simukufunika jakisoni, ndipo izi ndizothandiza, makamaka kwa munthu wogwira ntchito. Ndinkamwa piritsi ndipo ndili phee. Sindinamvepo mavuto ena pandekha.

Ruslan, wazaka 57, Omsk

Mankhwalawa sanakwane. Mwina chifukwa amatenga okodzetsa, koma kufooka thupi kwambiri. Zinthu zikuipiraipiraipira. Tsiku lotsatira, kupweteketsa mtima kunayamba, kudwala mutu kwambiri, kupweteka m'mimba, zizindikiro zonse za kuledzera zidayamba. Dotoloyo akuti ndi momwe ndawonetsera lactic acidosis. Ndinafunika kusintha mankhwalawo.

Sergey, wazaka 34, Samara

Posachedwa, ndidapezeka kuti ndili ndi matenda ashuga a 2. Ndanenepa kwambiri, zomwe zakhala chimodzi mwazomwe zimayambitsa matendawa. Dokotala adalemba mapiritsi a Mepharmil. Ndi zakudya ndi mapiritsi, kulemera kunayamba kuchepa. Tsopano ndikofunikira kuti zizisungidwa nthawi zonse. Mkhalidwe wofanananso tsopano wakhala wabwinoko. Mphamvu ndi mphamvu zambiri zidawonekera. Kuphatikiza apo, kumwa mapiritsi ndikosavuta kuposa jakisoni. Ngakhale ndimakhutira ndi chithandizo ndi mankhwalawa.