Apidra Solostar ndi mankhwala omwe ali ndi vuto la hypoglycemic. Amagwiritsidwa ntchito pochiza matenda amtundu wa 1 komanso matenda a shuga a 2 mwa akuluakulu, achinyamata ndi ana. Asanaikidwe, ndikofunikira kuchita kafukufuku wa kuchuluka kwa shuga m'magazi.
Dzinalo Losayenerana
Insulin glulisin
ATX
A10AV06
Kutulutsa mafomu ndi kapangidwe kake
Mankhwala amapezeka mu mawonekedwe a yankho la makonzedwe amkati wamafuta ochepa, okhala ndi mawonekedwe amadzimadzi osalala. Kuphatikizidwa kwa 1 ampoule kumaphatikizapo zinthu izi:
- insulin glulisin (100 PIECES);
- metacresol;
- sodium kolorayidi;
- trometamol;
- hydrochloric acid;
- madzi a jakisoni;
- polysorbate.
Apidra Solostar ndi mankhwala omwe ali ndi vuto la hypoglycemic.
Zotsatira za pharmacological
Zinthu zomwe zimagwira ndimalo opaka insulin ya anthu. Imakhala ndi mphamvu mwachangu, yomwe ndiyofupikitsa kuposa ya insulin yachilengedwe, nthawi yayitali. Mankhwala ali ndi izi:
- imayendetsa kagayidwe kazakudya;
- amatsitsa shuga wamagazi polimbikitsa kukoka kwa glucose ndi minofu yofewa;
- amalepheretsa gluconeogeneis mu chiwindi;
- amachepetsa kuwonongeka kwa mafuta mu adipocytes;
- zimalepheretsa kuwonongeka kwa mapuloteni ndikuwonjezera kupanga mapuloteni.
Pharmacokinetics
Mankhwalawa ali ndi magawo a pharmacokinetic:
- Zogulitsa. Mankhwalawa akaperekedwa kwa odwala omwe ali ndi matenda a shuga omwe amadalira insulin, achire a insulin glulisin m'magazi amapezeka pambuyo pa ola limodzi. Kwambiri kuzungulira kwa chinthu chimadziwika pambuyo mphindi 80. Kukhalapo kwa mankhwala m'magazi ndi mphindi 100.
- Kugawa. Mankhwalawa amagawidwa ngati sungunuka wa munthu.
- Kuswana. Mothandizidwa ndi subcutaneous, glulisin imachoka m'thupi mwachangu kuposa insulin yachilengedwe. Kutha kwa theka-moyo kumatha osaposa mphindi 40, pomwe insulin yaumunthu imatha theka la moyo wofanana ndi mphindi 85.
Zizindikiro zogwiritsidwa ntchito
Mankhwalawa amagwiritsidwa ntchito pochiza matenda amisempha otengera shuga.
Contraindication
Mankhwalawa ali ndi zotsutsana zotsatirazi:
- kusalolera kwa yogwira mankhwala ndi zina zothandizira;
- hypoglycemia.
Momwe mungatenge Apidra Solostar
Apidra amalowa jekeseni pang'ono ndi singano yopyapyala m'dera la minyewa yotakata kapena khoma lamkati lam'mimba musanadye kapena mutangodya. Mankhwala ayenera kukhala mu achire regimens, kuphatikizapo insulin wa sing'anga kapena nthawi yayitali kuchitira. Mtundu wachiwiri wa matenda ashuga, ungagwiritsidwe ntchito limodzi ndi omwe ali m'magulu a hypoglycemic. Mlingo wa mankhwalawa umakhazikitsidwa kutengera kutengeka kwa thupi ndi insulin.
Njira yothetsera vutoli imaperekedwa pogwiritsa ntchito cholembera kapena chipangizo chogwiritsa ntchito pampu chomwe chimapereka kulowetsedwa kosalekeza kwa zinthu m'thupi la adipose. Pakugwiritsa ntchito kwatsopano kulikonse, tsamba la jekeseni liyenera kusintha. Kuchuluka kwa mayamwidwe kumadalira malo a jakisoni, zolimbitsa thupi ndi mtundu wa chakudya chomwe chimatengedwa. Mukamayambitsa khoma lam'mimba, chinthu chogwira ntchito chimamezedwa mwachangu. Poika jakisoni, kulowetsedwa kwa mankhwalawo m'mitsempha ndi mitsempha kuyenera kupewedwa. Ndikosatheka kutikita minofu jakisoni mutachotsa singano.
Mankhwalawa amagwiritsidwa ntchito pochiza matenda amisempha otengera shuga.
Zotsatira zoyipa Apidra Solostar
Zotsatira zoyipa za Apidra sizisiyana ndi zoyipa zomwe zimachitika poyambitsa ma insulin ena osakhalitsa.
Pa khungu
Subcutaneous makonzedwe a njirayi amathanso kuyambitsa redness, kutupa komanso khungu pakhungu. Zizindikirozi zimasiya kuonekera patatha masiku angapo chiyambireni chithandizo. Nthawi zina mavuto amayambitsidwa ndi kugwiritsidwa ntchito kwa ma antiseptic othandizira kuchiza khungu lisanachitike kapena jakisoni wolakwika.
Kuchokera kumbali ya kagayidwe
Zotsatira zoyipa kwambiri za glulisin ndi hypoglycemia, momwe zizindikiro zotsatirazi zimachitikira:
- kufooka kwa minofu;
- kutopa;
- kuchepa kowoneka bwino;
- mutu
- chikumbumtima;
- kugwidwa kogwedeza;
- kumva kwamphamvu kwa njala;
- thukuta kwambiri;
- mantha
- kugwedezeka kwamiyendo;
- zokonda mtima.
Ndi pafupipafupi kuukiridwa kwambiri glypoglycemia, mitsempha imadwala, zomwe zimathandizira kukulitsa zochitika zowopsa, kuphatikizapo kupha chikomokere.
Matupi omaliza
Zizindikiro za ziwengo ku mankhwalawa ndi izi:
- kusanza khungu;
- urticaria;
- anaphylactic zimachitika;
- kukanikiza ululu kumbuyo kwa sternum;
- kuukira kwa mphumu;
- dontho la kuthamanga kwa magazi;
- kukoka kwamtima;
- malungo.
Zokhudza mphamvu pakuwongolera njira
Apidra imatha kuyambitsa matenda amitsempha omwe amachepetsa kuchuluka kwa zochitika zama psychomotor, kotero mukamachiza muyenera kukana kuyendetsa galimoto ndi zida zina zovuta.
Malangizo apadera
Gwiritsani ntchito mu ukalamba
Posankha mlingo wa odwala okalamba, adokotala ayenera kuganizira za zovuta za impso zomwe zimachepetsa kufunika kwa insulin.
Kupatsa ana
Mankhwala ali osavomerezeka chifukwa cha mpumulo wa matenda ashuga ana osakwana zaka 6.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Insulin glulisin ilibe teratogenic kapena mutagenic pa mwana wosabadwayo, komabe, panthawi yoyembekezera, mankhwalawa ayenera kugwiritsidwa ntchito mosamala. Pa yoyamwitsa, kusintha kwa mlingo kungafunike.
The ntchito aimpso kuwonongeka
Ndi kuphwanya kokwanira kwa kachitidwe ka mawonedwe, mlingo wa mankhwalawa umachepetsedwa.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Kulephera kwambiri kwa chiwindi, mankhwalawa amagwiritsidwa ntchito mosamala.
Mankhwala ochulukirapo a Apidra Solostar
Ndi kuyambitsa insulin yambiri, hypoglycemia imachitika. Zizindikiro za hypoglycemia yofatsa imatha kuchotsedwa pakudya zakudya zokhala ndi shuga.
Mu pachimake bongo, limodzi ndi mkhutu chikumbumtima, mu mnofu kapena subcutaneous makonzedwe a glucagon amafunikira.
Kuchita ndi mankhwala ena
Mphamvu ya mankhwalawa imalimbikitsidwa pakaperekedwa limodzi ndi ma hypoglycemic wothandizidwa, ACE inhibitors, fibrate ndi pentoxifylline. Kuchita kwa glulisin kumachepetsedwa ndi glucocorticosteroids, isoniazid, salbutamol, adrenaline, diuretics. Beta-blockers imatha kufooketsa ndikuwonjezera mphamvu ya mankhwalawa. Kuphatikizika kwa pentamidine kumalimbikitsa kukula kwa hypoglycemia, yomwe pang'onopang'ono imasandulika kukhala hyperglycemia.
Kukhazikitsidwa kwa mankhwalawa sikulimbikitsidwa kuphatikiza ndi mowa.
Kuyenderana ndi mowa
Ethanol amatha kusintha magawo a pharmacokinetic pazomwe zimagwira, kotero kuyambitsa kwa mankhwala sikulimbikitsidwa kuti aphatikizidwe ndi zakumwa zoledzeretsa.
Analogi
Apidra ali ndi vuto lofananalo.
Kupita kwina mankhwala
Kodi ndingagule popanda kulandira mankhwala?
Mankhwalawa sangagulidwe popanda mankhwala.
Mtengo
Mtengo wapakati wa mankhwalawo ndi ma ruble 1900.
Zosungidwa zamankhwala
Njira yothetsera vutoli imasungidwa mufiriji popanda kuzizira.
Tsiku lotha ntchito
Mankhwalawa ndi oyenera kugwiritsa ntchito mkati mwa miyezi 24.
Mankhwalawa amasungidwa mufiriji.
Wopanga
Mankhwalawa amapangidwa ndi makampani opanga mankhwala Sanofi-Aventis Vostok, Russia ndi Sanofi-Aventis Deutschland, Germany.
Ndemanga
Natalia, wazaka 52, ku Moscow: "Mphamvu ya mankhwalawa ndi yofanana ndi insulin yachilengedwe. Apidra amasiyana chifukwa jakisoni amatha kudya musanadye. Ndimamwa mankhwalawa mphindi ziwiri asanadye, izi zimathandiza kupewa kuchuluka kwambiri kwa shuga m'magazi. cholembera chomwe chimathandizira kuyikapo. Ndizotheka momwe mungathere. "
Tamara, wazaka 56, Kursk: "Mankhwalawa adalembera amayi. Popeza ndi mayi wachikulire, mlingo woyeserera unadzakhala wotsika pang'ono. Mankhwalawa amagwira ntchito mwachangu, ngati pali zovuta zina malinga ndi malangizo omwe timapereka. Tisanadye chakudyacho. "Sindimakhala ndi vuto lililonse jakisoni. Ndakhala ndikugwiritsa ntchito insulin kwa miyezi isanu ndi umodzi, tili okondwa ndizotsatira zake."
