Trental 100 mg imathandizira kuyendetsa magazi ndi kukonza mkhalidwe wamitsempha yamagazi. Izi zimakhala ndi phindu pazinthu zosiyanasiyana ndipo zimaloleza kugwiritsa ntchito mankhwalawa osati monga angioprotector, komanso kuphatikizidwa ndi zovuta mankhwala othandizira kukonza minofu trophism, kuwonjezera kusintha kwa mpweya, komanso kuwonjezera kayendedwe ka mafupa amitsempha. Chidachi chimagwiritsidwa ntchito pothana ndi matenda angapo, kuthetsa matenda ena osachiritsika komanso pofuna kupewa.
Dzinalo Losayenerana
Trental ndi dzina lamalonda lamankhwala. INN yake malinga ndi malamulo a WHO ndi Pentoxifylline.
Trental imapangidwa mwanjira ya zinthu zam'mapiritsi ndi kuzimitsa kwamadzi kwa kulowetsedwa.
ATX
Gulu la mankhwala a vasodilators okhala ndi code ya ATX AC04A D03.
Kutulutsa mafomu ndi kapangidwe kake
Trental imapangidwa mwanjira ya zinthu zam'mapiritsi ndi kuzimitsa kwamadzi kwa kulowetsedwa.
Mapiritsi
Mapiritsi oyera oyera ali ndi mawonekedwe a convex. Pamaso pawo amaphimba zokutira zonunkhira zomwe zimalepheretsa kukoma kwa mankhwalawa ndikuchepetsa zovuta zoyipa za Trental pamimba. Zochita za mankhwala zimaperekedwa ndi gawo lalikulu la pentoxifylline. Piritsi lililonse lili ndi kuchuluka kwa 100 mg. Kukonzekera kwakutulutsidwa kotulutsidwa kumakhala komwe kumapezeka zomwe zili pazipangizo zapakati pa 400 mg. Zowonjezera zinalembedwera:
- wowuma chimanga;
- talcum ufa;
- mawonekedwe amadzimadzi a colloidal silicon dioxide;
- magnesium wakuba;
- lactose mfulu.
Mapiritsi amayikidwa mu ma PC 10. m'matuza.
Kuphimba kwamafilimu kumapangidwa ndi methacrylate, polyethylene glycol, sodium hydroxide, talc, zowonjezera E 171 (titanium dioxide).
Mapiritsi amayikidwa mu ma PC 10. m'matuza. Phukusi lakunja ndi makatoni, lili ndi matuza 6 ndi kapepala kamalangizo.
Njira Zothetsera
Mafuta mawonekedwe a mankhwalawa ndi njira yopanda utoto, womwe umapezeka m'mililita 5 yagalasi, yolongedzedwa m'makatoni ama 5 a ma PC. Zomwe zimagwira pano ndi pentoxifylline. Kuphatikizika kwake ndi 2% (20 mg mu 1 ml ya mankhwala). Gawo lothandiza ndi yankho la sodium chloride.
Mankhwalawa amaperekedwa nthawi zambiri ngati gawo la dontho, koma lingagwiritsidwenso ntchito ngati jakisoni wamkati. Kukhazikitsidwa kwa Trental intramuscularly ndikuloledwa.
Zotsatira za pharmacological
Trental ali ndi njira zingapo zochizira:
- kuphatikiza:
- vasodilating;
- adenosinergic;
- angioprotective;
- kukonzanso kwam'manja.
Trental ali ndi vasodilating achire kwenikweni.
Zonsezi zimachitika chifukwa cha ntchito ya pentoxifylline, yomwe imalepheretsa phosphodiesterase (PDE), yomwe imapangitsa kuti cAMP ikhale m'magazi amitsempha yamagazi ndi makoma amitsempha. Zotsatira zake, ziwiya zimakulirakulira, kukana kwa maofesi othandizira magazi kumachepa, miniti ndikuwonjezeka magazi kuchuluka kwake ndikumasunga kugunda kwa mtima. Kuzunza kwa ATP kumakulanso. Izi zimathandiza pa ntchito ya ubongo ndi kugwiririra ntchito kwa ubongo kwamkati.
Komabe pentoxifylline imakulitsa kuchepa kwa maselo ofiira a magazi ndi kutuluka kwa magazi. Amachepetsa ndende ya fibrinogen, amachepetsa ntchito ya leukocyte komanso kuthekera kwa kudziphatikiza kwa mapulateleti. Chifukwa cha kuchuluka kwa ziwiya zam'mapapu komanso kuwonjezeka kwa kamvekedwe ka minofu ya kupuma, kusinthana kwa mpweya pamlingo wamaselo, minofu ndi chamoyo chonse chimakulitsidwa.
Pharmacokinetics
Patatha ola limodzi mutamwa mankhwala, umangodutsa plasma. Pambuyo kusefera koyambirira mu chiwindi, bioavailability wa pentoxifylline pafupifupi 19%. Komabe, zida zake zowola, makamaka metabolite I, zimawonetseranso zochitika zambiri zamachitidwe am'magawo poyambira. Pachifukwa ichi, akukhulupirira kuti bioavailability ya mankhwalawa ndi apamwamba kuposa mtengo womwe wafotokozedwayo.
Mu thupi, pentoxifylline imapukusidwa kwathunthu. Kwa maola 4, pafupifupi mlingo wonse wotengedwa (mpaka 96%) umachotsedwa kudzera mu impso. Ndi kulephera kwambiri kwaimpso, nthawi imeneyi imawonjezeka, ndipo ndi kuwonongeka kwambiri kwa chiwindi, kukhudzana kwambiri kwa mankhwalawa.
Patatha ola limodzi mutamwa mankhwala, umangodutsa plasma.
Zizindikiro zogwiritsidwa ntchito
Trental imapangidwira kusintha minofu trophism ndikubwezeretsa ma microcirculation ndi ma pathologies awa:
- kuwononga atherosulinosis ziwiya zamiyendo, mosalekeza kukomoka;
- matenda ashuga angiopathy;
- kuphwanya kutumphuka kwa magazi chifukwa cha kutupa;
- angiotrophoneurosis;
- matenda a angioneuropathic, paresthesia;
- kuwonongeka kwa minofu chifukwa cha kulephera kwa microcirculatory (frostbite, gangrene, trophic ulceration, varicose veins);
- zovuta zamagazi chifukwa cha osteochondrosis;
- matenda a hemodynamic mu retina ndi choroid;
- matenda kupuma kugwirizana ndi zopinga phenthena (mphumu, emphysema, mitundu yayikulu ya bronchitis);
- ischemia, mkhalidwe wa pambuyo pake;
- otossteosis, kumva kuchepa kwa mtima chifukwa cha mtima;
- microcirculation yokhala ndi vuto la m'matumbo ndi zotulukapo (chizungulire, migraines, luntha ndi mnemonic);
- kusokonezeka kwa kugonana komwe kumayambitsidwa ndi zotupa zam'mimba.
Mankhwalawa angagwiritsidwenso ntchito kupewa kuti mwadzidzidzi pasakhale zovuta za ubongo.
Contraindication
Trental imakhala ndi zotsutsana zambiri:
- Kutengeka kwakukulu kwa pentoxifylline kapena zinthu zina za xanthine.
- Kusagwirizana ndi mankhwala othandizira.
- Kukhalapo kwa magazi kapena chizolowezi chake, hemorrhagic diathesis, kukha magazi muubongo kapena retina la owonera.
- Zilonda zam'mimba.
- Porphyria.
- Matenda a mtima pachimake.
- Nthawi yapakati.
- Kuyamwitsa.
- Zaka mpaka 18.
Mankhwalawa sagwiritsidwa ntchito pochiza ana osakwana zaka zambiri.
Komanso, mankhwala sayenera kuperekedwa kulowetsedwa pamaso pa arrhythmia, ochepa ochepa hypotension, atherosulinosis ya zotengera za mtima ndi ubongo (kupatula gawo loyambalo).
Ndi chisamaliro
Odwala omwe ali ndi vuto laimpso komanso kwa chiwindi ndi odwala omwe akuchira opaleshoni amafunika chisamaliro chapadera. Trental imalembedwa mosamala mu mtima kulephera komanso kugwiritsa ntchito mankhwala ena.
Momwe mungatenge Trental 100?
Dongosolo la mankhwala ndi mlingo wake amatsimikiziridwa ndi dokotala payekhapayekha. Mapiritsi sayenera kulumwa. Amadyedwa mukatha kudya, kutsukidwa ndi kuchuluka kwa madzi. M'pofunika kuchepetsa mlingo wocheperako mu matenda aimpso kapena kwa chiwindi. Ndi maziko a kuchepa kwa magazi, pazovuta zovuta za matenda a m'mimba ndi ischemia, chithandizo chiyenera kuyambitsidwa ndi mlingo wochepa, pang'onopang'ono kuwonjezera kuchuluka kwa mankhwalawa.
Imwani mapiritsi mutatha kudya, kumwa madzi oyenera.
Monga zosungunulira zolimbitsa kulowetsedwa ntchito:
- 0,9% sodium kolorayidi njira;
- shuga 5%;
- yankho la ringer.
Kuphatikiza pamodzi ndi zakumwa zina ndizotheka kokha ngati yankho lomveka lipezeka. Kuzungulira kwa pentoxifylline mu osakaniza kumatsimikiziridwa ndi zizindikiro za aliyense.
Kulowetsedwa kwa mtsempha wa mkati kumatha kukhala kwa ndege kapena kukokana. Panthawi ya ndondomeko, wodwalayo ayenera kugona. Kuyendetsa pang'onopang'ono ndikofunikira: nthawi ya jakisoni ndi mphindi 5, dontho la mankhwalawa liyenera kusungidwa osadutsa 100 mg mu 1 ora. Mukusokonezeka kwakukulu kwa magazi, nthawi ya kulowetsedwa ikhoza kukhala maola 24. Kuwerengeredwa kwa mankhwalawa pamenepa kumachitika chifukwa cha kuchuluka kwa thupi la wodwala mkati mwa kuchuluka kwa tsiku lililonse kwa mankhwalawo.
Ndi matenda a impso kapena chiwindi, kuyambitsa kulowetsedwa kumachepetsedwa. Ngati wodwalayo ali ndi vuto lotenga magazi, mankhwalawa amayamba ndi Mlingo wochepa, akuwonjezera pang'onopang'ono, poganizira zomwe akuchita.
Ndi makulidwe amtundu wa impso, kukhazikitsa njira yothetsera kumachepetsedwa.
Trental ikhoza kutumikiridwa intramuscularly, njirayi imafuna kuyambitsa kokhazikika. Kuphatikiza kwa pakamwa komanso kwa makolo a Trental amaloledwa kuganizira kuchuluka kwa pentoxifylline. Pofuna kupewa komanso kukonza, pali piritsi lokhalo lomwe limagwiritsidwa ntchito.
Kumwa mankhwala a shuga
Kuphatikiza ndi Trental, machitidwe a Insulin ndi mankhwala ena antidiabetes amathandizidwa. Chifukwa chake, pamaso pa matenda a shuga, mitundu yayikulu ya pentoxifylline iyenera kutumikiridwa ndi kuchepa kwa kuchuluka kwa othandizira a hypoglycemic pansi pazoyenera kuwongolera zodwala.
Kodi shuga abwinobwino mwa amuna ndi otani? Werengani zambiri mu nkhaniyi.
Kodi chiwonetsero cha matenda ashuga ndichani mwa akazi?
Kodi parsley ndi othandiza ku matenda a shuga a 2? Werengani zambiri mu nkhaniyi.
Masiku angati?
Kutalika kwa mankhwala kumatsimikiziridwa ndi dokotala kutengera chithunzi chonse, mawonekedwe a munthu payekha komanso mphamvu zake. Magawo okhathamiritsa magazi amathandizidwanso. Njira yochizira imatha kukhala masiku 10 mpaka miyezi ingapo.
Kutalika kwa mankhwala kumatsimikiziridwa ndi dokotala kutengera chithunzi chonse, mawonekedwe a munthu payekha komanso mphamvu zake.
Zotsatira zoyipa za Trental 100
Mankhwala nthawi zambiri amaloledwa. Koma pamakhala zinthu zina zosiyanasiyana zoyipa zomwe zimachitika mthupi.
Matumbo
Kuchepa kudya, kuchuluka kwa malovu kapena ma mucous nembanemba, kusanza, matumbo, kumva kukhuta m'mimba, kugaya chakudya m'mimba.
Zotsatira zoyipa za m'mimba thirakiti zimatha kusowa chakudya.
Hematopoietic ziwalo
Kusintha kwakuchepa kwa kapangidwe ka magazi, kuchepa kwa micrinogen.
Pakati mantha dongosolo
Chizungulire, migraine, mawonekedwe owonetsa, kusokonezeka kwakanthawi, nkhawa, kugona.
Kuchokera kwamikodzo
Kutupa.
Kuchokera ku kupuma
Kutuluka kwammphuno, bronchospasm.
Zotsatira zoyipa za kupuma - magazi ammphuno.
Pa khungu
Zingwe, kuyabwa, Hyperemia, kuchuluka kwa misomali.
Kuchokera ku genitourinary system
Kuwaza malo.
Kuchokera pamtima
Ululu mumtima, tachycardia, utachepa mavuto, arrhythmia, angina pectoris, magazi kuchokera mucous nembanemba kapena mtsempha wamagazi a pakhungu.
Kuchokera pamtima, zochitika za mawonekedwe a arrhythmia ndi tachycardia sizachilendo.
Kuchokera ku chitetezo chamthupi
Kukula kwa angioedema, anaphylactic mantha.
Pa mbali ya chiwindi ndi biliary thirakiti
Kuchulukitsa kwa cholecystitis, mawonekedwe amkati mwa cholestasis.
Matupi omaliza
Zochita monga urticaria, kupuma movutikira, kutupa, anaphylaxis.
Nthawi zina, thupi limakhala ngati urticaria.
Zokhudza mphamvu pakuwongolera njira
Mphamvu ya Trental pa ndende siinadziwike. Komabe, kusamala kuyenera kuchitidwa chifukwa cha kuthekera kwa chizungulire.
Malangizo apadera
Mukamamwa mankhwalawa, muyenera kuthana ndi magazi. Munthawi ya ntchito, ndikofunikira kuwongolera index ya hematocrit ndi hemoglobin. Ngati matenda amitsempha yam'mimba amachitika panthawi ya chithandizo, kugwiritsa ntchito Trental kuyenera kuyimitsidwa nthawi yomweyo. Osuta amatha kuona kuchepa kwa mankhwalawa.
Gwiritsani ntchito panthawi yoyembekezera komanso mkaka wa m`mawere
Panthawi yobala mwana, Trental sanalembedwe. Pakutalika kwa chithandizo, kuyamwitsa kuyenera kusiyidwa.
Panthawi yobala mwana, Trental sanalembedwe.
Kulembera Trental kwa ana 100
Palibe deta yotsimikizika yokhudza momwe mankhwalawa amathandizira thupi la ana, motero sikulimbikitsidwa kupereka mankhwalawa kwa odwala osakwana zaka 18.
Gwiritsani ntchito mu ukalamba
Chifukwa cha kuwonongeka kwa chiwindi komanso mawonekedwe aimpso, odwala okalamba ayenera kuyikidwa mankhwala ochepetsedwa ndikuwonetsetsa momwe alili.
The ntchito aimpso kuwonongeka
Kulephera kwapa kumabweretsa kuwonjezeka kwa nthawi ya chimbudzi cha pentoxifylline, kuwerengetsa ndikotheka. Mlingo wa trental uyenera kuchepetsedwa.
Kulephera kwa renal kumabweretsa kuwonjezeka kwa nthawi ya chimbudzi cha pentoxifylline, kuwerengetsa ndikotheka, mlingo wa Trental uyenera kuchepetsedwa.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Kuwonongeka kwa chiwindi kumapangitsanso kuchuluka kwa mankhwalawa. Pankhaniyi, tikulimbikitsidwa kuchepetsa mlingo ndi 30-50%.
Kuchulukitsa kwa Trental 100
Zizindikiro za kuchuluka kwa mulingo:
- kufooka
- kusanza
- kuzizira;
- kukomoka
- hyperemia;
- arrhythmia;
- kuchuluka kwa mtima;
- dontho la kuthamanga kwa magazi;
- kuphwanya Reflex zimachitika;
- kukokana
- magazi m'mimba.
Chizindikiro chimodzi cha kuphwanya Mlingo ndi kufooka.
Muzimutsuka m'mimba ndi kupita kuchipatala.
Kuchita ndi mankhwala ena
Ndikofunikira kuganizira kuyanjana kwa Trental ndi mankhwala ena. Nthawi zina, pamakhala kuwonjezeka kwa gawo limodzi mwa mankhwalawo kapena chiwopsezo chosafunikira chikuwonjezeka. Zochita Zamankhwala:
- Ndi mankhwala a antihypertensive (nitrate, ACE zoletsa, etc.) - chiwopsezo cha hypotension.
- Ndi ma anticoagulants ndi maantibayotiki - mwayi wokhetsa magazi.
- Ndi Theophylline, kuwonjezereka kwa ndende yake.
- Ndi cimetidine ndi ciprofloxacin - kuchuluka kwa plasma ya pentoxifylline.
- Ndi xanthines - kuchulukaonjezeka wamanjenje.
- Ndi mankhwala a anti-glycemic - onenepa kwambiri ndi hypoglycemia.
Kuyenderana ndi mowa
Pa mankhwala, tikulimbikitsidwa kuti musamwe mowa.
Pa mankhwala, tikulimbikitsidwa kuti musamwe mowa.
Analogi
Analogs of Trental pazogwira ntchito:
- Pentoxifylline;
- Agapurin;
- Pentilin;
- Maluwa;
- Pentohexal;
- Arbiflex;
- Flexital ndi ena.
Flowerpot - analogue ya Trental yogwira ntchito.
Mankhwala ena a gulu lomwelo la mankhwala, mwachitsanzo, Duzofarm, nawonso ali ndi vuto lofananalo.
Kupita kwina mankhwala
Trental sikugulitsidwa.
Kodi ndingagule popanda kulandira mankhwala?
Mankhwalawa amaperekedwa malinga ndi mankhwala.
Mankhwalawa amaperekedwa malinga ndi mankhwala.
Mtengo Trental 100
Mtengo wa kulowetsedwa uli pafupi ma ruble 147. Mtengo wa piritsi la mankhwalawa umachokera ku ma ruble 450.
Zosungidwa zamankhwala
Chochita chimasungidwa kutali ndi ana pa kutentha kosaposa + 25 ° C.
Tsiku lotha ntchito
Mapiritsiwa ndi oyenera zaka 4 kuyambira tsiku lotulutsidwa. Alumali moyo wa yankho ndi zaka 5.
Wopanga
Mankhwalawa amapangidwa ndi kampani yopanga mankhwala ku India Aventis Pharma Limited.
Ndemanga za 100
Trental ali ndi malingaliro abwino kuchokera kwa onse odwala ndi madokotala.
Madokotala
Otavin P.N., katswiri wa zamitsempha, Novosibirsk.
Trental ndi wabwino kwambiri pakuchiza matenda osokoneza bongo komanso othandizira. Odwala ambiri ali ndi malingaliro abwino. Ndikufuna kuzindikira kusowa kwa hepatotoxicity ndi kulekerera bwino kwa mankhwalawa.
Odwala
Semen, wazaka 41, mzinda wa Penza.
Ndinkakhala ndi vuto losamva. Atatenga Trental, sikuti adangoyamba kumva bwino, komanso adalimbikitsidwa. Masiku angapo oyambilira, mutu wanga sunazizire pang'ono, ndipo panali zovuta zina zoyipa.
Alice, wazaka 26, Samara.
Agogo anga aakazi ankayikiridwa ndi matenda a dementia, koma panali dotolo waluso yemwe adapereka Trental. Pambuyo pa chithandizo, sanazindikiridwe. Agogo aamuna adakhalanso ndi moyo, adasekedwa ndipo adasinthanso zojambulajambula.