Xelevia amatanthauza othandizira a hypoglycemic. Amagwiritsidwa ntchito ngati gawo lalikulu la zovuta kuchizira matenda amitundu iwiri. Ili ndi mphamvu yosasintha ya hypoglycemic.
Dzinalo Losayenerana
Mankhwala a INN: Sitagliptin
Dzinalo losavomerezeka mdziko la mankhwala Xelevia ndi Sitagliptin.
ATX
Code ya ATX: A10VN01
Kutulutsa mafomu ndi kapangidwe kake
Amapezeka m'mapiritsi okhala ndi filimu. Mapiritsi okhala ndi kirimu, padziko utoto wamafilimu mbali imodzi amalemba "277", mbali inayo amakhala osalala.
Chofunikira chachikulu ndi sitagliptin phosphate monohydrate mu Mlingo wa 128,5 mg. Zowonjezera: cellcrystalline cellulose, calcium hydrogen phosphate, croscarmellose sodium, magnesium stearate, magnesium stearyl fumarate. Kuphimba kwamafilimu kumakhala ndi mowa wa polyvinyl, titanium dioxide, polyethylene glycol, talc, chikasu ndi red iron oxide.
Mankhwalawa amapezeka m'matuza a mapiritsi 14. Phukusi la makatoni mumakhala matuza 2 ndi malangizo ogwiritsira ntchito.
Onaninso: Malangizo ogwiritsira ntchito mankhwalawa Chitosan.
Ndi mitundu iti ya glucometer imodzi yamkono yomwe imagwira ntchito kwambiri?
Kumene ndi momwe mungapangire insulin mu matenda a shuga - werengani m'nkhaniyi.
Zotsatira za pharmacological
Adalinganiza zochizira matenda amtundu wachiwiri. Makina ochitapo kanthu amatengera zovuta za enzyme DPP-4. Zomwe zimagwiritsidwa ntchito zimasiyanasiyana mu zochita zake za insulin ndi ena antiglycemic othandizira. Kukumana kwa glucose wodalira insulinotropic timakulitsa.
Pali kuponderezedwa kwa kubisalira kwa glucagon ndi maselo apancreatic. Izi zimathandiza kuchepetsa kapangidwe ka shuga m'chiwindi, chifukwa cha zomwe zizindikiro za hypoglycemia zimachepetsedwa. Kuchita kwa sitagliptin cholinga chake ndikulepheretsa hydrolysis ya pancreatic enzymes. Glucagon secretion imachepetsedwa, potero imalimbikitsa kutulutsa kwa insulin. Poterepa, index ya glycosylated insulin ndi kuchuluka kwa shuga m'magazi kumachepetsedwa.
Xelevia cholinga chake ndi kuchiza matenda amtundu wa 2 shuga.
Pharmacokinetics
Mutatha kumwa mapiritsiwo mkati, chogwira ntchito chimatengedwa mwachangu kuchokera m'mimba. Kudya kumakhudza mayamwidwe. Kuchuluka kwake kwa magazi kumatsimikizika patatha maola angapo. Bioavailability ndiwambiri, koma kuthekera kumangiriza ku zomanga mapuloteni ndizochepa. Metabolism imachitika m'chiwindi. Mankhwalawa amachotsedwa m'thupi limodzi ndi mkodzo pochita kusefukira kwa impso onse osasinthika komanso mawonekedwe a metabolites ofunikira.
Zizindikiro zogwiritsidwa ntchito
Pali zisonyezo zingapo zachindunji zogwiritsira ntchito mankhwalawa:
- monotherapy kusintha kagayidwe ka glycemic kwa odwala omwe ali ndi matenda a shuga a 2;
- kuyamba mankhwala ovuta ndi metformin mtundu 2 matenda ashuga;
- mankhwalawa a matenda amtundu wa 2 shuga, pamene zakudya ndi zolimbitsa thupi sizigwira ntchito;
- kuwonjezera pa insulin;
- kukonza glycemic control kuphatikiza ndi sulfonylurea zotumphukira;
- kuphatikiza mankhwala a shuga a mtundu wachiwiri ndi thiazolidatediones.
Contraindication
Contraindication mwachindunji pakugwiritsa ntchito mankhwalawa, omwe akuwonetsedwa mu malangizo ogwiritsira ntchito, ndi:
- Hypersensitivity zigawo zikuluzikulu za mankhwala;
- nthawi ya pakati ndi mkaka wa m`mawere;
- zaka mpaka 18;
- matenda ashuga ketoacidosis;
- mtundu 1 matenda a shuga;
- matenda a impso.
Xelevia amagwiritsidwa ntchito pochiza matenda amtundu wa 2 shuga, pamene zakudya ndi masewera olimbitsa thupi sizipereka zotsatira.
Ndi chisamaliro chachikulu, Xelevia imalembedwa kwa anthu omwe ali ndi vuto lalikulu laimpso komanso pakati, odwala omwe ali ndi mbiri ya kapamba.
Kutenga Xelevia?
Mlingo ndi nthawi yayitali ya chithandizo zimatengera kuopsa kwa vutoli.
Popanga monotherapy, mankhwalawa amatengedwa koyamba tsiku lililonse la 100 mg patsiku. Mlingo womwewo umawonedwa mukamagwiritsa ntchito mankhwalawa limodzi ndi metformin, insulin ndi sulfonylureas. Mukamapangira zovuta mankhwala, ndikofunikira kuti muchepetse mlingo wa insulin yomwe imatengedwa kuti mupewe kukula kwa hypoglycemia.
Osamwa kawiri mlingo wa mankhwalawa tsiku limodzi. Ndi kusintha kwakukuru pa thanzi, kusintha kwa mankhwala kungafunike. Nthawi zina, mapiritsi theka kapena kotala ndi omwe amapatsidwa, omwe amangokhala ndi zotsatira za placebo. Mlingo wa tsiku ndi tsiku umatha kusiyanasiyana ndikuwonetsa kuwonekera kwa matendawa ndikuyenda bwino kwa mankhwalawa.
Zotsatira zoyipa za Xelevia
Mukamamwa Xelevia, zotsatirazi zimakhala zotsatirazi:
- thupi lawo siligwirizana;
- kusowa kwa chakudya
- kudzimbidwa
- kukokana
- tachycardia;
- kusowa tulo
- paresthesia;
- kusakhazikika mtima.
Nthawi zina, kuchuluka kwa zotupa m'mimba kumatheka. Mankhwalawa ndi chizindikiro. Woopsa, limodzi ndi kupweteka, hemodialysis amachitidwa.
Zokhudza mphamvu pakuwongolera njira
Kafukufuku wolondola pazotsatira za mankhwalawa pazomwe zimachitika ndi kuchuluka kwa chidwi sizinachitike. Zowonongera zoyipa pakuwongolera njira zovuta ndi magalimoto sizimayembekezeredwa.
Malangizo apadera
Pali chiopsezo chokhala ndi hypoglycemia, motero ndikofunika kuti pang'onopang'ono muchepetse insulin yogwiritsidwa ntchito ndi zizindikiro zofunika. Chenjezo limaperekedwa kwa okalamba, odwala matenda a chiwindi, impso ndi mtima dongosolo.
Gwiritsani ntchito mu ukalamba
Kwenikweni, okalamba odwala safuna kusintha kwa mlingo. Koma ngati vutolo likuipiraipira kapena chithandizo sichikupereka zotsatira zomwe zikuyembekezeka, ndibwino kusiya kumwa mapiritsiwo kapena kusintha kuti muchepe.
Odwala okalamba sayenera kusintha mlingo wa mankhwala a Xelevia.
Kupatsa ana
Osagwira ntchito machitidwe a ana.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Palibe chidziwitso chokwanira chokhudzana ndi zomwe zimachitika pa mwana wosabadwayo. Chifukwa chake, kugwiritsa ntchito mankhwalawa pa gestation ndizoletsedwa.
Popeza palibe zambiri zodalirika zokhudzana ndi mankhwalawa ngati mkaka umadutsa mkaka wa m'mawere, ndi bwino kusiya kuyamwitsa ngati chithandizo chimenecho chikufunika.
The ntchito aimpso kuwonongeka
Mankhwala omwe mumalandira adzadalira mtundu wa creatinine chilolezo. Mokulira, amachepetsa mlingo wololedwa. Ngati vuto losakwanira la impso, mlingo woyambirira ungasinthidwe kukhala 50 mg patsiku. Ngati chithandizo sichimapereka chithandizo chofunikira, muyenera kuthetsera mankhwalawo.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Ndi kufooka pang'ono kwa impso, kusintha kwa mankhwalawa sikofunikira. Mlingo wa tsiku lililonse pamenepa ayenera kukhala 100 mg. Pokhapokha ngati chiwindi chikulephera kwenikweni, mankhwalawa amachitika ndi mankhwalawa.
Ndi chilema chachikulu cha chiwindi, Xelevia sichikuperekedwa.
Mankhwala osokoneza bongo a Xelevia
Palibe milandu ya bongo. Mkhalidwe wowopsa wa mankhwala poyizoni ungachitike pokhapokha kumwa limodzi mopitilira 800 mg. Pankhaniyi, zizindikiro za zoyipa zimachulukirachulukira.
Chithandizo chimaphatikizapo kuchiritsa kwam'mimba, kupititsa patsogolo mankhwala othandizira komanso kukonza. Ndikotheka kuchotsa poizoni m'thupi pogwiritsa ntchito dialysis yayitali, chifukwa muyezo hemodialysis imagwira ntchito wofatsa milandu bongo.
Kuchita ndi mankhwala ena
Mankhwalawa amatha kuphatikizidwa ndi metformin, warfarin, njira zina zakutsitsira pakamwa. Ma pharmacokinetics a yogwira ntchito sasintha pogwiritsa ntchito mankhwala ophatikizira a ACE, othandizira ma antiplatelet, mankhwala otsitsa a lipid, beta-blockers ndi calcium blockers.
Izi zimaphatikizaponso mankhwala osokoneza bongo a anti-yotupa, antidepressants, antihistamines, proton pump inhibitors, ndi mankhwala ena kuti athetse kusokonekera kwa erectile.
Akaphatikizidwa ndi Digoxin ndi Cyclosporine, kuwonjezeka pang'ono kwa kugwiritsidwa ntchito kwa plasma yamagazi kumawonedwa.
Kuyenderana ndi mowa
Simungathe kumwa mankhwalawa ndi mowa. Zotsatira zamankhwala zimachepa, ndipo zizindikiro za dyspeptic zimangokulira.
Analogi
Mankhwalawa ali ndi ma analogi angapo ofanana ndi iwo malinga ndi zomwe zimagwiritsidwa ntchito ndi zomwe zimakhala nazo. Zodziwika kwambiri pakati pawo ndi:
- Sitagliptin;
- Sitagliptin phosphate monohydrate;
- Januvius;
- Yasitara.
Kupita kwina mankhwala
Xelevia ingagulidwe ku malo ogulitsa mankhwala pokhapokha ngati mwalandira mankhwala.
Kodi ndingagule popanda kulandira mankhwala?
Zosatheka.
Mtengo
Mtengo wake umachokera ku 1500 mpaka 1700 rubles. Phukusi lililonse ndipo zimatengera magawo ogulitsa ndi ogulitsa ma pharmacy.
Zosungidwa zamankhwala
Sankhani malo owuma komanso amdima, kutali ndi ana aang'ono, ndi kutentha kosaposa + 25 ° C.
Tsiku lotha ntchito
Zaka 2 kuyambira tsiku lomwe limatulutsidwa. Osagwiritsa ntchito nthawi imeneyi.
Wopanga
Kampani yopanga: "Berlin-Chemie", Germany.
Sungani Xelevia kutali ndi ana aang'ono.
Ndemanga
Mikhail, wazaka 42, Bryansk
Dokotala adalangiza kuti atenge Xelevia ngati chithandizo chachikulu. Pambuyo pa mwezi wogwiritsa ntchito, shuga yofulumira idachulukirachulukira, isanakwanitse zaka 5, tsopano ifika pa 6-6.5. Zomwe thupi limachita pakulimbitsa thupi lasintha. M'mbuyomu, mutayenda kapena kusewera masewera, shuga adagwa kwambiri, ndipo kwambiri, chizindikirocho chinali pafupifupi 3. Mukamamwa Xelevia, shuga pambuyo pakuchita masewera olimbitsa thupi amatsika pang'onopang'ono, kenako amabwerera mwakale. Adayamba kumva bwino. Chifukwa chake ndimalimbikitsa mankhwalawa.
Alina, wazaka 38, Smolensk
Ndimavomereza Xelevia monga chowonjezera cha insulin. Ndakhala ndikudwala matenda a shuga kwa zaka zingapo ndipo ndayesera mankhwala ambiri osakanikirana. Ndimakonda kwambiri izi. Mankhwalawa amangoyankha shuga wambiri. Ngati yatsitsidwa, ndiye kuti mankhwalawo 'sangawakhudze' ndikuwukweza kwambiri. Amachita pang'onopang'ono. Palibe spikes mu shuga masana. Palinso chinthu china chabwino chomwe sichinafotokozedwe mu malangizo ogwiritsira ntchito: kusintha kwa zakudya. Kulakalaka kumachepetsedwa pafupifupi theka. Izi ndi zabwino.
Mark, wazaka 54, Irkutsk
Mankhwalawo adabwera nthawi yomweyo. Izi zisanachitike, adatenga Januvia. Pambuyo pa iye, sizinali bwino. Patatha miyezi ingapo kumwa Xelevia, sikuti shuga wokhazikika yekha, komanso thanzi labwino. Ndimamva mphamvu zambiri, osafunikira kumangodandaula. Ndinatsala pang'ono kuyiwala kuti hypoglycemia ndi chiani. Shuga samalumpha, kumira ndikukula pang'onopang'ono, pang'ono ndi pang'ono, komwe thupi limayankha bwino.
