Momwe mungagwiritsire ntchito Lorista 100 pa matenda ashuga

Lorista 100 ndi mankhwala othandizira antihypertensive omwe cholinga chake ndi chithandizo cha matenda oopsa.

Dzinalo Losayenerana

Dongosolo la malonda la mankhwalawa ndi Lorista, dzina lodana ndi mayiko ena onse ndi Losartan.

Lorista 100 ndi mankhwala othandiza a antihypertensive.

ATX

Malinga ndi gulu la ATX, mankhwala a Lorista ali ndi code C09CA01. Gawo loyamba la code (С09С) limatanthawuza kuti mankhwalawo ndi a gulu la njira zosavuta za angiotensin 2 antagonists (mapuloteni omwe amalepheretsa kuchuluka), gawo lachiwiri la code (A01) ndi dzina la Lorista, womwe ndi woyamba mankhwala pamndandanda wofanana wa mankhwalawa.

Kutulutsa mafomu ndi kapangidwe kake

Lorista amapezeka mu mawonekedwe a miyala, yokutidwa ndi utoto wa film yoteteza, wokhala ndi mawonekedwe ozungulira. Chofunikira chachikulu cha nyukiliya ndi potaziyamu losartan. Opezekapo ndi monga:

• cellulose 80, yophatikiza 70% lactose ndi 30% mapadi;
• magnesium wakuba;
• silika.

Kupanga mafilimu kumakhala ndi:

• propylene glycol;
• hypromellose;
• titanium dioxide.

Mapiritsi amayikidwa mu ma meshes apulasitiki, osindikizidwa ndi zojambula za aluminium, 7, 10 ndi 14 ma PC. Bokosi la makatoni limatha kukhala ndi mapiritsi 7 kapena 14 (1 kapena 2 mapaketi 7 ma PC.), 30, 60 ndi 90 mapiritsi (3, 6 ndi 9 mapaketi 10 ma PC., Motsatana).

Chofunikira chachikulu cha Lorista 100 ndi losartan.

Zotsatira za pharmacological

Angiotensin 2 ndipuloteni yomwe imapangitsa kuti magazi azitha. Zotsatira zake pamapuloteni amtundu (cell receptors) zimabweretsa:

• Kutalika kwa mitsempha yayitali ndi yolimba;
• kusungunuka kwa madzi ndi sodium, zomwe zimachulukitsa kuchuluka kwa magazi omwe amayenda mthupi;
• kuwonjezera kuchuluka kwa aldosterone, vasopressin, norepinephrine.

Kuphatikiza apo, chifukwa cha nthawi yayitali ya vasospasm ndi madzimadzi owonjezera, minofu yamtima imakakamizidwa kugwira ntchito ndi katundu wowonjezereka, zomwe zimabweretsa kukula kwa hypertrophy khoma la myocardial. Ngati sanatenge kanthu, ndiye kuti matenda oopsa ndi matenda oopsa am'mitsempha yamanzere am'mimba adzathetsa kuchepa kwa magazi ndi minyewa ya mtima, yomwe imakhudza kulephera kwa mtima, kusokonezeka kwa magazi ku ziwalo, makamaka ubongo, maso, ndi impso.

Mfundo zazikuluzikulu za chithandizo cha antihypertensive ndikuletsa zotsatira za angiotensin 2 pama cell a thupi. Lorista ndi mankhwala omwe amatchinga mokwanira zochitika zonse zathupi zamapuloteni awa.

Pambuyo pakulowetsa, Lorista amalowetsedwa ndikuwupanga m'chiwindi.

Pharmacokinetics

Pambuyo polowa m'thupi, mankhwalawa amalowetsedwa ndikuwupanga m'chiwindi, kudzipatula mu metabolites yogwira komanso yolimba. Kuphatikizika kwakukulu kwa mankhwalawa m'magazi kulembedwa pambuyo pa ola limodzi, ndipo metabolite yake yogwira pambuyo pa maola 3-4. Mankhwalawa amachotseredwa kudzera impso ndi matumbo.

Kafukufuku wa odwala wamwamuna ndi wamkazi omwe amatenga Lorista adawonetsa kuti kuchuluka kwa losartan m'magazi mwa akazi kumakhala kochulukirapo kawiri kuposa kwa amuna, ndipo kuchuluka kwa metabolite yake kuli chimodzimodzi.

Komabe, chowonadi choterocho chilibe tanthauzo lachipatala.

Kodi chimathandiza ndi chiyani?

Lorista amalembera matenda monga:

• matenda oopsa;
• kulephera kwa mtima kosatha.

Kuphatikiza apo, mankhwalawa amagwiritsidwa ntchito:

• kuteteza impso za odwala omwe ali ndi matenda amtundu wa 2 kuchokera pakuperewera kwa matenda a impso, kukula kwa nthawi yotsika ya matendawa, kufuna kufalikira kwa ziwalo, kuchepetsa proteinuria ndi kufa kwa mitundu iyi yamatenda;
• achepetse chiopsezo chokhala ndi myocardial infarction, stroke, komanso kufa chifukwa chopanga mtima kulephera.

Kodi ndiyenera kuthana ndi vuto lotani?

Lorista sakhala wa mankhwala omwe amachepetsa kuthamanga kwa magazi, koma ndi mankhwala opangira matenda oopsa kwa nthawi yayitali. Amatengedwa kwa miyezi ingapo ndipo malinga ndi momwe dokotala amafotokozera.

Lorista sinafotokozeredwe zakuphwanya kwambiri chiwindi.

Contraindication

Mankhwalawa sanatchulidwe komwe wodwala akuvutika:

• tsankho lililonse pazinthu zomwe zimapanga mankhwala;
• kuphwanya kwambiri chiwindi;
• matenda a biliary thirakiti;
• kobadwa nako lactose tsankho;
• shuga-galactose malabsorption syndrome;
• kuchepa kwa lactose;
• kusowa kwamadzi;
• Hyperkalemia
• matenda a shuga oletsa kuperewera kapena kuchepa mphamvu ku matenda aimpso kwambiri ndipo akutenga Aliskiren.

Lorista amaletsedwa kugwiritsidwa ntchito panthawi yomwe ali ndi pakati komanso mkaka wa m'mawere, komanso kwa odwala osakwana zaka 18. M'mbuyomu, palibe chidziwitso pakugwiritsa ntchito mankhwalawa.

Lorista ndi oletsedwa kugwiritsidwa ntchito panthawi yapakati.

Ndi chisamaliro

Chenjezo makamaka mukamalandira Lorista ayenera kumwedwa ngati wodwala:

• ali ndi vuto lochepa lamitsempha yama impso yonseyo (kapena 1 mtsempha wamagazi ngati impso ndiyookhayo);
• ali mkhalidwe pambuyo kumuika impso;
• odwala ndi aortic stenosis kapena mitral vala;
• ali ndi hypertrophic cardiomyopathy;
• odwala ndi mtima mtima arrhythmia kapena ischemia;
• ali ndi matenda amitsempha;
• ili ndi mbiri yakuthekera kwa angioedema;
• ali ndi matenda amphumo;
• ali ndi voliyumu yochepetsedwa yoyendayenda magazi chifukwa chotenga ma diuretics.

Kutenga Lorista 100?

Mankhwalawa amatengedwa 1 nthawi patsiku, mosasamala nthawi kapena chakudya. Ndi kuthamanga kwa magazi, mlingo woyambira ndi 50 mg. Kupanikizika kuyenera kukhazikika pambuyo pa masabata 3-6. Ngati izi sizingachitike, mlingowo umakulitsidwa mpaka 100 mg. Mlingo wambiri ndiwololedwa.

Kulephera kwa mtima kosatha, mankhwalawa amayamba ndi kuchuluka kwa 12,5 mg ndipo amachulukitsidwa sabata iliyonse, ndikubweretsa 50 kapena 100 mg.

Odwala omwe ali ndi vuto la chiwindi amalimbikitsidwa kuti agwiritse ntchito mlingo wochepetsedwa wa mankhwalawa, womwe umatsimikiziridwa ndi dokotala potengera momwe wodwalayo alili.

Ndi kuchepa kwa mitsempha ya impso zonse, muyenera kusamala mukamatenga Lorista.

Rhinitis ndi chosowa kwambiri mutatenga Lorista.

Lorista sinafotokozeredwe hyperkalemia.

Ndi matenda ashuga

Mtundu wachiwiri wa matenda a shuga, mankhwalawa amapatsidwa mlingo wa 50 kapena 100 mg, malingana ndi momwe wodwalayo alili. Lorista imatha kuthandizidwa limodzi ndi mankhwala ena a antihypertensive (okodzetsa, alpha ndi beta adrenergic blockers), insulin ndi mankhwala ena a hypoglycemic, mwachitsanzo, glitazones, zotumphukira za sulfonylurea, ndi zina zambiri.

Zotsatira zoyipa Lorista 100

Lorista imalekeredwa bwino ndipo kawirikawiri imayambitsa zovuta zoyipa. Nthawi zambiri, zimachitika kuchokera:

• kupuma dongosolo - mu mawonekedwe a kupuma movutikira, sinusitis, laryngitis, rhinitis;
• khungu - mawonekedwe a pakhungu pakhungu ndi kuyabwa;
• mtima dongosolo - mu mawonekedwe a angina pectoris, hypotension, atrive fibrillation, kukomoka;
• chiwindi ndi impso - mu mawonekedwe opuwala ziwalo;
• minofu ndi yolumikizana minofu - mu mawonekedwe a myalgia kapena arthralgia.

Palibe mavuto obwera chifukwa cha chitetezo chamthupi omwe adadziwika.

Matumbo

Ndikosowa kwambiri kwa wodwala kumva kupweteka kwam'mimba kapena kusokonezeka komwe kumagwira ntchito pamimba - m'mimba, nseru, kusanza, kudzimbidwa kapena kutsegula m'mimba.

Hematopoietic ziwalo

Matendawa nthawi zambiri amakula, ndipo kawirikawiri thrombocytopenia.

Pakati mantha dongosolo

Nthawi zambiri, chizungulire chimachitika, kawirikawiri - kupweteka mutu, kugona, kusokonezeka kwa tulo, kuda nkhawa, kusokonezeka, kukhumudwa, kulota.

Nthawi yamankhwala a Lorista, kuyendetsa kumaloledwa.

Matupi omaliza

Ndi osowa kwambiri kumwa mankhwala kungayambitse khungu vasculitis, angioedema a nkhope ndi kupuma thirakiti, anaphylactic zimachitika.

Zokhudza mphamvu pakuwongolera njira

Nthawi yamankhwala a Lorista, kuyendetsa kumaloledwa. Kusiyana kwina kungakhalepo komwe wodwalayo amathandizika ndi mankhwalawa mu mawonekedwe a chizungulire, makamaka poyambira chithandizo, pomwe thupi limazolowera mankhwalawa.

Malangizo apadera

1. Mankhwala osavomerezeka kuti agwiritsidwe ntchito ndi odwala omwe ali ndi vuto loyambirira la hyperaldrateonism, chifukwa samapereka zotsatira zabwino.
2. Odwala omwe ali ndi vuto la kusowa kwa madzi mu electrolyte ayenera kuyikidwa pa Lorista muyezo wochepetsedwa kuti asayambitse ochepa.
3. Ngati vuto la matenda oopsa ndi kusowa kwa matenda a parathyroid, ndiye kuti Lorista akuyenera kutengedwa limodzi ndi mankhwala omwe amapangitsa kuti minyewa ya m'mimba izigwira bwino komanso imathandizira impso.

Gwiritsani ntchito mu ukalamba

Palibe kusintha kwa mlingo womwe ukufunika.

Kusankhidwa kwa ana a Lorista 100

Mankhwalawa sanalembedwe kwa ana ndi achinyamata osakwana zaka 18, chifukwa palibe zambiri zosakwanira pachilichonse chomwe chikukula.

Lorista sanalembedwe kwa ana ndi achinyamata osakwana zaka 18.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Nthawi ya kubereka imasemphana ndi kugwiritsa ntchito Lorista, chifukwa izi zimatha kubweretsa zovuta zapakhomo pakukula kwa mwana wosabadwa, kuphatikiza imfa yake. Chifukwa chake, mimba ikapezeka, mankhwalawo amasiya pomwepo ndipo njira ina yochiritsira imasankhidwa.

Pokonzekera kukhala ndi pakati pa amayi omwe amatenga Lorista, muyenera choyamba kumaliza maphunziro.

Kuyesa kwa nyama kwawonetsa kuti kugwiritsa ntchito mankhwalawa pamagawo osiyanasiyana a mimba nthawi zambiri kumabweretsa ma oligohydramnios (oligohydramnios) mwa mayi ndipo, chifukwa chake, kwa fetal pathologies monga:

• mafupa matupi;
• hypoplasia yamapapu;
• hypoplasia la chigaza;
• kulephera kwaimpso;
• ochepa hypotension;
• anuria

Ngati nkotheka kuti mayi woyembekezera asankhe mankhwala ena, ndikofunikira:

1. Muchenjezeni mayi za mavuto obwera chifukwa cha mwana wosabadwa.
2. Nthawi zonse yesani mkhalidwe wa mwana wosabadwayo kuti muwone kuwonongeka kwina.
3. Lekani mankhwalawa ngati mukukula kwa oligohydramnios (madzi osakwanira amniotic). Kugwiritsa ntchito mosalekeza ndikotheka kokha ngati ndikofunikira kwa mayi

Palibe chidziwitso chokhudza kuti losperan amadutsa mkaka wa m'mawere. Chifukwa chake, panthawi yoyamwitsa, Lorista ayenera kusiyidwa, ndipo ngati izi sizingatheke, ndiye kuti kudyetsa kuyenera kusokonezedwa.

Fluconazole imachepetsa ndende ya Lorista mu plasma.

Overdose Lorista 100

Zambiri pazokhudza mankhwala osokoneza bongo sizokwanira. Mwambiri, mankhwala osokoneza bongo amatha kuonekera mu mawonekedwe a kuchepa kwambiri kwa kuthamanga kwa magazi, tachycardia kapena bradycardia. Zikatero, chithandizo chamankhwala chovomerezeka nchoyenera. Hemodialysis sichimapatula losartan ndi metabolite yake yogwira.

Kuchita ndi mankhwala ena

1. Lorista imagwirizana ndi mankhwala:
   • ndi hydrochlorothiazide;
   • ndi warfarin;
   • ndi phenobarbital;
   • ndi digoxin;
   • ndi cimetidine;
   • ndi ketoconazole;
   • ndi erythromycin;
   • ndi sulfinpyrazone;
   • ndi probenecid.
2. Fluconazole ndi rifampicin amachepetsa kuchuluka kwa Lorista m'madzi a m'magazi.
3. Kugwiritsa ntchito munthawi yomweyo mankhwala omwe ali ndi mchere wa potaziyamu komanso zinthu zina zowonjezera potaziyamu kumabweretsa kuwonjezereka kwa kuchuluka kwa potaziyamu mu seramu yamagazi.
4. Lorista amalimbikitsa kuchotsedwa kwa lifiyamu, chifukwa chake mukamamwa mankhwala mokwanira, ndikofunikira kuyang'anira kuchuluka kwa lifiyamu mu seramu yamagazi.
5. Kugwiritsidwa ntchito kwa kuphatikizira kwa Lorista ndi NSAIDs kumachepetsa hypotensive zotsatira.
6. Kulandiridwa movuta kwa Lorista ndi antidepressants ndi antipsychotic nthawi zambiri kumayambitsa hypotension.
7. Kulandila kwa Lorista ndi mtima glycosides kumatha kupangitsa arrhythmia ndi chamkati tachycardia.

Lozap ndi analogue ya Lorista.

Kuyenderana ndi mowa

Anthu omwe ali ndi vuto la matenda oopsa salimbikitsidwa kumwa mowa ngakhale pang'ono Mlingo, chifukwa mowa umathandiza kuwonjezera magazi komanso kusokoneza kugwira ntchito kwa minofu ya mtima. Kumwa kophatikizana kwa mowa ndi Lorista nthawi zambiri kumabweretsa kulephera kupuma, kusayenda bwino, kufooka ndi zotsatira zina zosasangalatsa, chifukwa chake madokotala salimbikitsa kuphatikiza mankhwalawa ndi zakumwa zoledzeretsa.

Analogi

Ma Analogs a Lorista ndi:

1. Lozap (Slovakia);
2. Presartan 100 (India);
3. Losartan Krka (Slovenia);
4. Lorista N (Russia);
5. Losartan Pfizer (India, USA);
6. Pulsar (Poland).

Kupita kwina mankhwala

Malinga ndi malangizo ogwiritsira ntchito, a Lorista amagawidwa m'mafakisoni kokha mwa mankhwala.

Presartan-100 - analogue ya Lorista.

Kodi ndingagule popanda kulandira mankhwala?

Lorista angagulidwe ku pharmacy popanda mankhwala a dokotala.

Mtengo wa Lorista 100

Mtengo wa mapiritsi 30 a mankhwalawa ku malo ogulitsa mankhwala ku Moscow ndi ma ruble 300., mapiritsi 60 - ma ruble 500., mapiritsi 90 - ma ruble 680.

Zosungidwa zamankhwala

Lorista amasungidwa kutentha kutentha kosaposa + 25 ° C.

Tsiku lotha ntchito

Alumali moyo wa mankhwala 5 zaka.

Wopanga

Makampani opanga mankhwala atulutsira Lorista:

• LLC "KRKA-RUS", Russia, Istra;
• JSC "Krka, dd, Novo mesto", Slovenia, Novo mesto.

Ndemanga pa Lorista 100

Lorista ali ndi ndemanga zambiri zabwino kuchokera kwa madokotala komanso odwala.

Omvera zamtima

Vitaliy, wazaka 48, wazaka 23, Novorossiysk: "Nthawi zambiri ndimagwiritsa ntchito Lorista pantchito zachipatala. Mankhwalawa adatsimikizira kuphatikiza kwa matenda oopsa komanso gout, chifukwa kuphatikiza pazowonjezera, amathandizira kuchepetsa uric acid m'magazi ndipo imadzetsa mtima wake. "Kuchita bwino kwa mankhwalawa kumatengera makamaka momwe mulingo wosankhidwa bwino, kuvomerezeka kwa creatinine ndi kulemera kwa thupi kumazindikiridwa."

Olga, wazaka 50, wazaka 25, ku Moscow: "Lorista ndi chida chotsika mtengo komanso chothandiza kuchiza matenda oopsa, omwe ali ndi mapindu awiri ofunika: kukhudzika wodwala komanso kusakhalapo kouma - zotsatira zoyenda zomwe zimagwirizana ndi mankhwala ambiri ochizira ofanana."

Odwala

Marina, wazaka 50, Nizhny Novgorod: "Ndakhala moyo wanga wonse kumudzi, koma sindingathe kudzitcha wathanzi: Ndakhala ndikuvutika ndi mtima kwa zaka zopitilira 10, zomwe zikupita patsogolo. Palibe njira yothandizidwira pafupipafupi - famu yayikulu yomwe singasiyidwe. Lorista ndiye chipulumutso chokha. "kumangokhala kuthinana komanso kuthamanga kwa mtima, kumawonjezera kupirira.

Victoria, wazaka 56, Voronezh: "Ndakhala ndikudwala matenda oopsa kwa zaka zoposa 10, ndinayesa mankhwala ambiri omwe amachepetsa kuthamanga kwa magazi, koma nthawi yonseyo panali zovuta zina. Lorista adabwera nthawi yomweyo: osakhosomola, kapena chizungulire, kuchuluka kwa kugwedezeka kumatha, thupi limakulirakulira. "